Page last updated: 2024-11-03

procainamide and Pregnancy

procainamide has been researched along with Pregnancy in 32 studies

Procainamide: A class Ia antiarrhythmic drug that is structurally-related to PROCAINE.
procainamide : A benzamide that is 4-aminobenzamide substituted on the amide N by a 2-(diethylamino)ethyl group. It is a pharmaceutical antiarrhythmic agent used for the medical treatment of cardiac arrhythmias.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"Emergencies include arrhythmias, acute coronary syndrome, peripartum cardiomyopathy and hypertensive disorders."2.44[Arrhythmias during pregnancy]. ( Trappe, HJ, 2008)
" Special consideration, however, must be given with regard to drug selection and dosage in order to avoid adverse effects on the mother and fetus."2.36Antiarrhythmic drug therapy during pregnancy. ( Elkayam, U; Frishman, W; Rotmensch, HH, 1983)
"Extensive serologic changes occur in systemic lupus erythematosus (SLE) which are probably secondary to unknow primary cause(s)."2.35Serologic abnormalities in spontaneous and drug-induced systemic lupus erythematosus. ( Dubois, EL, 1975)
"The management of arrhythmias during pregnancy is, in principle, similar to that in nonpregnant patients, however, special consideration must be given, to avoid adverse fetal effects."1.31[Treatment of cardiac arrhythmia in pregnant women]. ( Halawa, B, 2000)
"A 25-week fetus with severe hydrops fetalis secondary to supraventricular tachycardia was treated with fetal intramuscular injections of digoxin in conjunction with maternal intravenous digoxin, followed by oral digoxin and subsequently by oral procainamide therapy."1.28Fetal supraventricular tachycardia and hydrops fetalis: combined intensive, direct, and transplacental therapy. ( Hallak, M; Huhta, JC; Nazir, M; Neerhof, MG; Perry, R, 1991)
"Fetal cardiac arrhythmias are usually first suspected on the basis of auscultatory findings during routine examination in pregnancy."1.27Treatment of fetal cardiac arrhythmias. ( Stewart, PA; Wladimiroff, JW, 1985)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199025 (78.13)18.7374
1990's3 (9.38)18.2507
2000's4 (12.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Trappe, HJ1
Meyer, K1
Zhang, H1
Zhang, L1
DE CECCO, L1
CIMELLARO, M1
PINE, HL1
FOX, L1
SHOOK, DM1
Ognio, E1
Chiavarina, B1
Peterka, M1
Mariggiò, MA1
Viale, M1
Lesch, M1
Lewis, E1
Humphries, JO1
Ross, RS1
Kelle, L1
Bota, L1
Rotmensch, HH1
Elkayam, U1
Frishman, W1
Runge, M1
Pittard, WB1
Glazier, H1
Williams, BJ1
Abreu, ME1
Given, BD1
Phillippe, M1
Sanders, SP1
Dzau, VJ1
Ueland, K1
McAnulty, JH1
Ueland, FR1
Metcalfe, J1
Dumesic, DA1
Silverman, NH1
Tobias, S1
Golbus, MS1
Allen, NM1
Page, RL1
Simpson, LL1
Marx, GR1
D'Alton, ME1
Halawa, B1
Dubois, EL2
McCrum, ID1
Guidry, JR1
Lima, JJ1
Kuritzky, PM1
Schentag, JJ1
Jusko, WJ1
Cowan, RH1
Waldo, AL1
Harris, HB1
Cassady, G1
Brans, YW1
Hallak, M1
Neerhof, MG1
Perry, R1
Nazir, M1
Huhta, JC1
Polak, PE1
Stewart, PA2
Hess, J1
Weiner, CP1
Thompson, MI1
Wladimiroff, JW1
Strain, L1
Saheta, NP1
Kewitz, H1
Tuffanelli, DL1
Shore, RN1
MacLachlan, TB1
Fries, D1
Zech, P1
Brunat, N1
Bouletreau, P1
Traeger, J1
Ledwich, JR1
Fay, JE1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
"Automated External Defibrillator (AED) Use in Out-of-Hospital Cardiac Arrest: A New Algorithm Named One Shock Per Minute"[NCT00139542]Phase 35,107 participants (Actual)Interventional2005-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

7 reviews available for procainamide and Pregnancy

ArticleYear
[Arrhythmias during pregnancy].
    Deutsche medizinische Wochenschrift (1946), 2008, Volume: 133, Issue:36

    Topics: Adenosine; Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Defibrillators, Impla

2008
Antiarrhythmic drug therapy during pregnancy.
    Annals of internal medicine, 1983, Volume: 98, Issue:4

    Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Breast Feeding; Digitalis

1983
[Therapy of arrhythmia during pregnancy].
    Deutsche medizinische Wochenschrift (1946), 1984, Jun-15, Volume: 109, Issue:24

    Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Biotransformation; Coumar

1984
Special considerations in the use of cardiovascular drugs.
    Clinical obstetrics and gynecology, 1981, Volume: 24, Issue:3

    Topics: Anti-Arrhythmia Agents; Anticoagulants; Cardiac Glycosides; Cardiovascular Agents; Disopyramide; Diu

1981
Serologic abnormalities in spontaneous and drug-induced systemic lupus erythematosus.
    The Journal of rheumatology, 1975, Volume: 2, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Antibodies, Anti-Idiotypic; Antibodies, Antinuclear; Anticonvulsants

1975
Iatrogenic cardiovascular disease (an aspect of preventive cardiology).
    Indian heart journal, 1968, Volume: 20, Issue:4

    Topics: Abnormalities, Drug-Induced; Analgesics; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Antidepressi

1968
A primer of collagen disease.
    Minnesota medicine, 1974, Volume: 57, Issue:10

    Topics: Administration, Topical; Adult; Anti-Inflammatory Agents; Antibodies; Central Nervous System Disease

1974

Other Studies

25 other studies available for procainamide and Pregnancy

ArticleYear
Direct effect of cocaine on epigenetic regulation of PKCepsilon gene repression in the fetal rat heart.
    Journal of molecular and cellular cardiology, 2009, Volume: 47, Issue:4

    Topics: Animals; Azacitidine; Base Sequence; Binding Sites; Cocaine; DNA Methylation; Enzyme Repression; Epi

2009
[The association of procainamide and succinylcholine in anesthesia for cesarean section].
    Quaderni di clinica ostetrica e ginecologica, 1961, Volume: 16

    Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Cesarean Section; Female; Pain Management; Pregnanc

1961
PAROXYSMAL VENTRICULAR TACHYCARDIA COMPLICATING PREGNANCY.
    The American journal of cardiology, 1965, Volume: 15

    Topics: Adolescent; Drug Therapy; Electrocardiography; Female; Humans; Pregnancy; Pregnancy Complications; P

1965
Study of feasibility of the treatment with procainamide hydrochloride and cisplatin in pregnant mice.
    Chemico-biological interactions, 2006, Dec-15, Volume: 164, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Embryo Loss; Embryo, Mammalian;

2006
Paroxysmal ventricular tachycardia in the absence of organic heart disease. Report of a case and review of the literature.
    Annals of internal medicine, 1967, Volume: 66, Issue:5

    Topics: Adolescent; Adult; Child; Electrocardiography; Female; Humans; Male; Pregnancy; Pregnancy Complicati

1967
[Efficacy of drug therapy in atrial fibrillation].
    Zeitschrift fur arztliche Fortbildung, 1981, May-15, Volume: 75, Issue:10

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Atrial Fibrillation; Coronary Vessel Anomalies; Digitalis

1981
Procainamide excretion in human milk.
    The Journal of pediatrics, 1983, Volume: 102, Issue:4

    Topics: Acecainide; Adult; Arrhythmias, Cardiac; Female; Humans; Infant, Newborn; Male; Milk, Human; Postpar

1983
Cardiotoxicity of perinatal lead exposure.
    Progress in clinical and biological research, 1983, Volume: 140

    Topics: Adenylyl Cyclases; Aging; Animals; Animals, Newborn; Arrhythmias, Cardiac; Calcium; Drug Interaction

1983
Procainamide cardioversion of fetal supraventricular tachyarrhythmia.
    The American journal of cardiology, 1984, May-15, Volume: 53, Issue:10

    Topics: Adult; Echocardiography; Female; Fetal Diseases; Humans; Pregnancy; Prenatal Diagnosis; Procainamide

1984
Transplacental cardioversion of fetal supraventricular tachycardia with procainamide.
    The New England journal of medicine, 1982, Oct-28, Volume: 307, Issue:18

    Topics: Digoxin; Echocardiography; Female; Fetal Diseases; Fetal Heart; Humans; Infant, Newborn; Injections,

1982
Procainamide administration during pregnancy.
    Clinical pharmacy, 1993, Volume: 12, Issue:1

    Topics: Acecainide; Administration, Oral; Adult; Cardiac Pacing, Artificial; Female; Humans; Pregnancy; Preg

1993
Management of supraventricular tachycardia in the fetus.
    Current opinion in obstetrics & gynecology, 1995, Volume: 7, Issue:5

    Topics: Adult; Digoxin; Female; Fetal Diseases; Humans; Pregnancy; Procainamide; Tachycardia, Supraventricul

1995
[Treatment of cardiac arrhythmia in pregnant women].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2000, Volume: 9, Issue:50

    Topics: Adrenergic beta-Antagonists; Alcohol Drinking; Arrhythmias, Cardiac; Digoxin; Electric Countershock;

2000
Procainamide-induced psychosis.
    JAMA, 1978, Sep-15, Volume: 240, Issue:12

    Topics: Arrhythmias, Cardiac; Bipolar Disorder; Female; Humans; Male; Middle Aged; Placebos; Pregnancy; Proc

1978
Fetal uptake and neonatal disposition of procainamide and its acetylated metabolite: a case report.
    Pediatrics, 1978, Volume: 61, Issue:3

    Topics: Acetylation; Adult; Arrhythmias, Cardiac; Female; Fetus; Humans; Infant, Newborn; Maternal-Fetal Exc

1978
Neonatal paroxysmal supraventricular tachycardia with hydrops.
    Pediatrics, 1975, Volume: 55, Issue:3

    Topics: Digoxin; Edema; Electrocardiography; Female; Fetal Diseases; Furosemide; Heart Ventricles; Humans; I

1975
Fetal supraventricular tachycardia and hydrops fetalis: combined intensive, direct, and transplacental therapy.
    Obstetrics and gynecology, 1991, Volume: 78, Issue:3 Pt 2

    Topics: Adult; Digoxin; Female; Fetal Diseases; Fetus; Humans; Hydrops Fetalis; Injections, Intramuscular; I

1991
Complete atrioventricular dissociation and His bundle tachycardia in a newborn: problems in prenatal diagnosis and postnatal management.
    International journal of cardiology, 1989, Volume: 22, Issue:2

    Topics: Atrioventricular Node; Bundle of His; Cesarean Section; Diagnosis, Differential; Digoxin; Echocardio

1989
Direct treatment of fetal supraventricular tachycardia after failed transplacental therapy.
    American journal of obstetrics and gynecology, 1988, Volume: 158, Issue:3 Pt 1

    Topics: Adult; Digoxin; Female; Fetal Diseases; Fetus; Humans; Maternal-Fetal Exchange; Pregnancy; Procainam

1988
Treatment of fetal cardiac arrhythmias.
    British journal of hospital medicine, 1985, Volume: 34, Issue:3

    Topics: Amiodarone; Arrhythmia, Sinus; Arrhythmias, Cardiac; Chromosome Aberrations; Chromosome Disorders; D

1985
Failure of procainamide to induce a systemic lupus erythematosus-like disease in animals.
    Toxicology and applied pharmacology, 1972, Volume: 21, Issue:2

    Topics: Animals; Antibodies, Antinuclear; Blood Cell Count; Blood Volume Determination; Body Weight; Criceti

1972
[Drugs as cause of diseases].
    Der Internist, 1974, Volume: 15, Issue:1

    Topics: Abnormalities, Drug-Induced; Berlin; Contraceptives, Oral; Cortisone; Drug-Related Side Effects and

1974
Pregnancy with myotonic dystrophy: course, complications and management.
    Obstetrics and gynecology, 1971, Volume: 38, Issue:3

    Topics: Abortion, Habitual; Adult; Contraception; Electromyography; Female; Fetal Death; Hemorrhage; Humans;

1971
[Lupus nephropathy. Diagnosis, evolution and treatment].
    Lyon medical, 1968, Sep-15, Volume: 220, Issue:37

    Topics: Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Female; Humans; Kidney Diseases; Lupu

1968
Idiopathic recurrent ventricular fibrillation.
    The American journal of cardiology, 1969, Volume: 24, Issue:2

    Topics: Adult; Electrocardiography; Female; Humans; Injections, Intravenous; Pregnancy; Pregnancy Complicati

1969