procainamide has been researched along with Myasthenia Gravis in 3 studies
Procainamide: A class Ia antiarrhythmic drug that is structurally-related to PROCAINE.
procainamide : A benzamide that is 4-aminobenzamide substituted on the amide N by a 2-(diethylamino)ethyl group. It is a pharmaceutical antiarrhythmic agent used for the medical treatment of cardiac arrhythmias.
Myasthenia Gravis: A disorder of neuromuscular transmission characterized by fatigable weakness of cranial and skeletal muscles with elevated titers of ACETYLCHOLINE RECEPTORS or muscle-specific receptor tyrosine kinase (MuSK) autoantibodies. Clinical manifestations may include ocular muscle weakness (fluctuating, asymmetric, external ophthalmoplegia; diplopia; ptosis; and weakness of eye closure) and extraocular fatigable weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles (ocular myasthenia). THYMOMA is commonly associated with this condition.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Respiratory failure was induced secondary to procainamide alone since no N-acetyl-procainamide level was detectable." | 1.28 | Procainamide-induced myasthenic crisis. ( Godley, PJ; Karboski, JA; Morton, TA; Tami, JA, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yeh, TM | 1 |
| Tami, JA | 2 |
| Krolick, KA | 1 |
| Godley, PJ | 1 |
| Morton, TA | 1 |
| Karboski, JA | 1 |
| Drachman, DA | 1 |
| Skom, JH | 1 |
3 other studies available for procainamide and Myasthenia Gravis
| Article | Year |
|---|---|
Exacerbated muscle dysfunction by procainamide in rats with experimental myasthenia gravis.
Topics: Animals; Antibodies; Autoimmune Diseases; Disease Models, Animal; Dose-Response Relationship, Drug; | 1992 |
Procainamide-induced myasthenic crisis.
Topics: Aged; Humans; Injections, Intravenous; Male; Myasthenia Gravis; Procainamide; Respiratory Insufficie | 1990 |
Procainamide---a hazard in myasthenia gravis.
Topics: Acetylcholine; Aged; Animals; Arrhythmias, Cardiac; Cats; Humans; Male; Muscles; Myasthenia Gravis; | 1965 |