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procainamide and Lupus Erythematosus, Systemic

procainamide has been researched along with Lupus Erythematosus, Systemic in 286 studies

Procainamide: A class Ia antiarrhythmic drug that is structurally-related to PROCAINE.
procainamide : A benzamide that is 4-aminobenzamide substituted on the amide N by a 2-(diethylamino)ethyl group. It is a pharmaceutical antiarrhythmic agent used for the medical treatment of cardiac arrhythmias.

Lupus Erythematosus, Systemic: A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.

Research Excerpts

ExcerptRelevanceReference
"Procainamide (PA) has been a mainstay of treatment against acute and chronic supraventricular and ventricular arrhythmias for more than 30 years."8.76Procainamide: clinical pharmacology and efficacy against ventricular arrhythmias. ( Giardina, EG, 1984)
"A 61-year-old man developed clinical lupus syndrome with positive antinuclear antibody, positive lupus erythematosus (LE) cell preparation, and diffuse proliferative glomerulonephritis following 26 months of procainamide therapy."8.76Glomerulonephritis in procainamide induced lupus erythematosus: report of a case and review of the literature. ( Erickson, DG; Foucar, E; Tung, KS, 1979)
"Procainamide hydrochloride-induced thrombocytopenia has infrequently been reported in the past."7.67Thrombocytopenia following sustained-release procainamide. ( Carlson, RJ; Gottlieb, AJ; Meisner, DJ, 1985)
"We report a case of the nephrotic syndrome occurring in a patient with procainamide induced LE."7.66Nephrotic syndrome in procainamide induced lupus nephritis. ( Bernheim, J; Blanc-Brunat, N; Colon, S; Labeeuw, M; Zech, P, 1979)
"A rare case of constrictive pericarditis in procainamide-induced lupus erythematosus syndrome is reported."7.65Constrictive pericarditis in procainamide-induced lupus erythematosus syndrome. ( Shah, A; Sunder, SK, 1975)
"A 63-year-old man developed an asymptomatic pleural effusion following the administration of 500 gm of procainamide hydrochloride over a six-month period."7.65Lupus erythematosus cells in pleural effusion: the initial manifestation of procainamide-induced lupus erythematosus. ( Carel, RS; Gutman, A; Shapiro, MS; Shoham, D, 1977)
"Prednisolone was administered."5.30[Procainamide-induced lupus in a patient with bilateral pleural effusion]. ( Hisauchi, K; Mitunaga, K; Miyake, S; Ohtani, Y; Sawada, M; Sumi, Y; Yamashita, Y; Yoshizawa, Y, 1998)
"Pericarditis has been reported to occur in from 14 to 18 per cent of the cases of procainamide-induced lupus erythematosus, and occasional reports of massive pericardial effusion, pericardial tamponade and constrictive pericarditis have appeared in the literature."5.26Procainamide-induced lupus erythematosus pericarditis encountered during coronary bypass sugery. ( Goldberg, MJ; Husain, M; Rubenfire, M; Wajszczuk, WJ, 1980)
"Procainamide (PA) has been a mainstay of treatment against acute and chronic supraventricular and ventricular arrhythmias for more than 30 years."4.76Procainamide: clinical pharmacology and efficacy against ventricular arrhythmias. ( Giardina, EG, 1984)
"A 61-year-old man developed clinical lupus syndrome with positive antinuclear antibody, positive lupus erythematosus (LE) cell preparation, and diffuse proliferative glomerulonephritis following 26 months of procainamide therapy."4.76Glomerulonephritis in procainamide induced lupus erythematosus: report of a case and review of the literature. ( Erickson, DG; Foucar, E; Tung, KS, 1979)
"Procainamide hydrochloride-induced thrombocytopenia has infrequently been reported in the past."3.67Thrombocytopenia following sustained-release procainamide. ( Carlson, RJ; Gottlieb, AJ; Meisner, DJ, 1985)
"An 82-year-old woman developed symptomatic reactive hypoglycemia in the same year she developed a lupus-like syndrome, probably secondary to the administration of procainamide or hydralazine."3.66Reactive hypoglycemia and insulin autoantibodies in drug-induced lupus erythematosus. ( Blackshear, PJ; Kahn, CR; Kriauciunas, KA; Rotner, HE, 1983)
"We report a case of the nephrotic syndrome occurring in a patient with procainamide induced LE."3.66Nephrotic syndrome in procainamide induced lupus nephritis. ( Bernheim, J; Blanc-Brunat, N; Colon, S; Labeeuw, M; Zech, P, 1979)
"Renal failure secondary to crescentic glomerulonephritis developed in a patient who had typical serologic features of drug-induced systemic lupus erythematosus after two years of therapy with procainamide."3.66Renal manifestations of drug-induced systemic lupus erythematosus. ( Charron, RC; Katz, A; Sheikh, TK, 1981)
"A rare case of constrictive pericarditis in procainamide-induced lupus erythematosus syndrome is reported."3.65Constrictive pericarditis in procainamide-induced lupus erythematosus syndrome. ( Shah, A; Sunder, SK, 1975)
"A 63-year-old man developed an asymptomatic pleural effusion following the administration of 500 gm of procainamide hydrochloride over a six-month period."3.65Lupus erythematosus cells in pleural effusion: the initial manifestation of procainamide-induced lupus erythematosus. ( Carel, RS; Gutman, A; Shapiro, MS; Shoham, D, 1977)
"Further study of drug-induced systemic lupus erythematosus is necessary in order to resolve these problems regarding pathogenesis."2.36Drug-induced systemic lupus erythematosus. ( Weinstein, A, 1980)
"Extensive serologic changes occur in systemic lupus erythematosus (SLE) which are probably secondary to unknow primary cause(s)."2.35Serologic abnormalities in spontaneous and drug-induced systemic lupus erythematosus. ( Dubois, EL, 1975)
"We analysed all ICSRs classified as 'systemic lupus erythematosus' according to the Medical Dictionary for Drug Regulatory Activities term (preferred term level) in VigiBase."1.51Drug-induced systemic lupus: revisiting the ever-changing spectrum of the disease using the WHO pharmacovigilance database. ( Arnaud, L; Chasset, F; Gavand, PE; Lambert, A; Lebrun-Vignes, B; Martin, T; Mertz, P; Muller, C; Salem, JE; Sibilia, J; Tebacher-Alt, M, 2019)
"Procainamide is a competitive DNA methyltransferase (Dnmt) inhibitor, hydralazine inhibits ERK pathway signaling thereby decreasing Dnmt expression, and in lupus T cells decreased ERK pathway signaling causing a similar Dnmt decrease."1.33Demethylation of the same promoter sequence increases CD70 expression in lupus T cells and T cells treated with lupus-inducing drugs. ( Lu, Q; Richardson, BC; Wu, A, 2005)
"Necrosis was induced by heating."1.33Quinidine and procainamide inhibit murine macrophage uptake of apoptotic and necrotic cells: a novel contributing mechanism of drug-induced-lupus. ( Ablin, J; Metzger, S; Mevorach, D; Trahtemberg, U; Verbovetski, I, 2005)
"Procainamide (PA) may cause drug-induced lupus, and its reactive metabolites, hydroxylamine-PA (HAPA) and nitroso-PA, are held responsible for this."1.30Procainamide, a drug causing lupus, induces prostaglandin H synthase-2 and formation of T cell-sensitizing drug metabolites in mouse macrophages. ( Abel, J; Degen, G; Gleichmann, E; Goebel, C; Mittmann, S; Sachs, B; Schraa, S; Uetrecht, J; Vogel, C; Wulferink, M, 1999)
"Prednisolone was administered."1.30[Procainamide-induced lupus in a patient with bilateral pleural effusion]. ( Hisauchi, K; Mitunaga, K; Miyake, S; Ohtani, Y; Sawada, M; Sumi, Y; Yamashita, Y; Yoshizawa, Y, 1998)
" Long term administration of this compound may induce a variety of immunological abnormalities, including antinuclear antibodies."1.28Pulmonary thromboembolism associated with procainamide induced lupus syndrome and anticardiolipin antibodies. ( Asherson, RA; Hughes, GR; Zulman, J, 1989)
"Though there are analogies to the systemic lupus erythematosus, we must take into consideration a diversity of diseases."1.27[Drug-induced lupus erythematosus syndrome. Pathogenesis and relation to systemic lupus erythematosus]. ( Wollina, U, 1984)
"Procainamide has a high propensity for the induction of an autoimmune response."1.27Autoallergic reactions induced by procainamide. ( Rubin, RL; Tan, EM, 1984)
"The sera of patients with systemic lupus erythematosus (SLE) and drug-induced lupus (DIL) were used to study the antigenic regions of histone 1 (H1) that bind antibodies in these sera."1.27Antibodies in procainamide-induced and systemic lupus erythematosus bind the C-terminus of histone 1 (H1). ( Fritzler, MJ; Gohill, J, 1987)
"Procainamide-induced lupus is a well-recognized syndrome, but the events leading up to clinical symptoms are obscure."1.27Serologic changes during induction of lupus-like disease by procainamide. ( Curd, JG; Johnson, AD; Nusinow, SR; Rubenson, DS; Rubin, RL; Tan, EM, 1986)
"Five drugs associated with systemic lupus erythematosus were studied for their effect on the salt-induced right-handed (B) to left-handed (Z) transition of poly(dG-me5dC) X poly(dG-me5dC)."1.27Effects of lupus-inducing drugs on the B to Z transition of synthetic DNA. ( Messner, RP; Thomas, TJ, 1986)
"Hydralazine was shown to interact with a soluble DNA-histone complex, and the resulting interaction rendered the histone moiety resistant to trypsin digestion."1.26The role of histones as nuclear autoantigens in drug-related lupus erythematosus. ( Portanova, JP; Tan, EM, 1981)
"Procainamide has become the most frequent cause of the drug-induced lupus syndrome."1.26SLE: idiopathic or drug-induced? ( Condemi, JJ, 1980)
"The procainamide group was compared with patients with spontaneous systemic lupus erythematosus (n = 15) and a normal control population (n = 40)."1.26Immune regulatory abnormalities produced by procainamide. ( Miller, KB; Salem, D, 1982)
"Approximately 8% of patients with systemic lupus erythematosus have drug induced disease."1.26[New aspects of drug induced lupus erythematosus (author's transl)]. ( Robinson, HM, 1978)
"Procainamide-induced systemic lupus erythematosus (SLE) is a well recognized clinical syndrome believed to be characterized by normocomplementemia."1.26Procainamide-induced systemic lupus erythematosus with hypocomplementemia. ( Diaz, R; Quigley, TJ; Rao, KV, 1977)
"These data suggest that systemic lupus erythematosus and procainamide-induced lupus may differ in the relative reversibility of a regulatory defect associated with a Con A responsive population of peripheral blood mononuclear (PBM) cells."1.26Inhibition of Con A mitogenesis by serum from procainamide-treated patients and patients with systemic lupus erythematosus. ( Cunningham-Rundles, S; Tannen, RH, 1982)
"To assess the efficacy, plasma drug concentrations and adverse effects of a new sustained release preparation of procainamide, 33 patients with heart disease were studied in an acute dose-ranging protocol and a chronic treatment protocol."1.26Efficacy, plasma concentrations and adverse effects of a new sustained release procainamide preparation. ( Bigger, JT; Fenster, PE; Giardina, EG; Marcus, FI; Mayersohn, M; Perrier, D, 1980)
"Pericarditis has been reported to occur in from 14 to 18 per cent of the cases of procainamide-induced lupus erythematosus, and occasional reports of massive pericardial effusion, pericardial tamponade and constrictive pericarditis have appeared in the literature."1.26Procainamide-induced lupus erythematosus pericarditis encountered during coronary bypass sugery. ( Goldberg, MJ; Husain, M; Rubenfire, M; Wajszczuk, WJ, 1980)
"Treatment with prednisone produced impressive amelioration of the pericarditis with no recurrence of the lupus erythematosis syndrome during a prolonged period of observation following cessation of corticosteroid therapy."1.25Pericardial tamponade. A presenting manifestation of procainamide-induced lupus erythematosus. ( Ghose, MK, 1975)

Research

Studies (286)

TimeframeStudies, this research(%)All Research%
pre-1990235 (82.17)18.7374
1990's31 (10.84)18.2507
2000's15 (5.24)29.6817
2010's4 (1.40)24.3611
2020's1 (0.35)2.80

Authors

AuthorsStudies
He, Y1
Sawalha, AH1
Arnaud, L1
Mertz, P1
Gavand, PE1
Martin, T1
Chasset, F1
Tebacher-Alt, M1
Lambert, A1
Muller, C1
Sibilia, J1
Lebrun-Vignes, B1
Salem, JE1
Pan, Q1
Guo, Y1
Guo, L1
Liao, S1
Zhao, C1
Wang, S1
Liu, HF1
Vedove, CD1
Del Giglio, M1
Schena, D1
Girolomoni, G1
Marzano, AV1
Vezzoli, P1
Crosti, C1
Katz, U1
Zandman-Goddard, G1
Wong-Baeza, C1
Hernández-Pando, R1
Reséndiz, A1
Tescucano, A1
Bustos, I1
Ibáñez, M1
Wong, C1
Baeza, I1
Lu, Q5
Kaplan, M1
Ray, D2
Zacharek, S1
Gutsch, D1
Richardson, B6
Deng, C2
Zhang, Z1
Rao, T1
Attwood, J1
Yung, R2
LADD, AT1
HAHN, AL1
KAPLAN, JM1
WACHTEL, HL1
CZARNECKI, SW1
SAMPSON, JJ1
KINGERY, FA1
COLMAN, RW1
STURGILL, BC1
Oelke, K1
Richardson, D1
Wu, A2
Hanash, S1
Richardson, BC4
Suwa, A1
Ablin, J1
Verbovetski, I1
Trahtemberg, U1
Metzger, S1
Mevorach, D1
Ohnishi, A1
Nonaka, Y1
Takei, S1
Zhou, Y1
Skipworth, GB1
Morris, JB1
Goldstein, N1
Rosin, JM1
Hanlon, TM1
Binkiewicz, A1
Feingold, M1
Necheles, TF1
McDevitt, DG1
Glascow, JF1
Compton-Smith, RN1
Fawcett, JW1
Siegel, M1
Lee, SL2
Peress, NS1
Giardina, EG2
Russell, PJ1
Doolan, TJ1
Webb, J1
Carr, GA1
DeSwarte, RD1
Ahmad, S1
Goldberg, MJ1
Husain, M1
Wajszczuk, WJ1
Rubenfire, M1
Fenster, PE2
Bigger, JT1
Mayersohn, M1
Perrier, D1
Marcus, FI1
González, ER1
Reidenberg, MM6
Bluestein, HG3
Redelman, D1
Zvaifler, NJ3
Uetrecht, JP1
Freeman, RW1
Woosley, RL2
Edwards, RL1
Rick, ME1
Wakem, CJ1
Tannen, RH3
Cunningham-Rundles, S1
Miller, KB1
Salem, D1
Jacobs, RP1
Blackshear, PJ1
Rotner, HE1
Kriauciunas, KA1
Kahn, CR1
Tan, EM10
Rubin, RL13
Klajman, A4
Kafri, B1
Shohat, T1
Drucker, I1
Moalem, T1
Jaretzky, A1
Goldberg, SK1
Lipschutz, JB1
Ricketts, RM1
Fein, AM1
Browning, CA1
Bishop, RL1
Heilpern, RJ1
Singh, JB1
Spodick, DH1
Wollina, U1
Sanfelippo, MJ1
Drayna, CJ1
Harmon, CE1
Portanova, JP3
Schifman, RB1
Garewal, H1
Shillington, D1
van Pham, C1
Noguchi, J1
Quismorio, FP1
Haywood, LJ1
Condemi, JJ4
Greenspan, AM1
Horowitz, LN1
Spielman, SR1
Josephson, ME1
Seligmann, H1
Potasman, I1
Bassan, H1
Weber, WW2
Wanner, WR1
Irvin, WS1
Holborow, EJ1
Weinstein, A1
Chubick, A1
Sheikh, TK1
Charron, RC1
Katz, A1
Schoen, RT1
Trentham, DE1
Cohen, MN1
Hess, EV4
Chokron, R1
Robert, A1
Rozensztajn, L1
Abuaf, N1
Dumoulin, P1
Valty, J1
Gupta, AK1
Porwal, P1
Nuwal, NK1
Gagrani, MR1
Porwal, K1
Healey, LA2
Parker, CW1
Fontiveros, ES1
Cumming, WJ1
Hudgson, P1
Yung, RL3
Quddus, J2
Chrisp, CE2
Johnson, KJ2
Alloway, JA1
Salata, MP1
Pauls, JD3
Edworthy, SM1
Fritzler, MJ5
Gavalchin, J1
Amento, EP1
Uetrecht, J3
Burlingame, RW1
Arnott, JE1
Totoritis, MC3
McNally, EM3
Johnson, AD2
Jiang, X1
Khursigara, G1
Cohen, MG1
Adams, LE2
Roberts, SM2
Donovan-Brand, R2
Zimmer, H1
McDonald, E1
Marino, C1
Muramatsu, M1
Nakajima, M1
Mori, M1
Sobashima, H1
Sano, H1
Katao, K1
Miyasaka, N1
Kretz-Rommel, A2
Duncan, SR1
Williams, R1
Johnson, K1
Phillips, C1
Stoolman, L1
Chang, S1
Ohtani, Y1
Sumi, Y1
Hisauchi, K1
Sawada, M1
Miyake, S1
Yamashita, Y1
Mitunaga, K1
Yoshizawa, Y1
McLaughlin, K1
Gholoum, B1
Guiraudon, C1
Jevnikar, A1
Muirhead, N1
Kameda, H1
Mimori, T1
Kaburaki, J1
Fujii, T1
Takahashi, T1
Akaishi, M1
Ikeda, Y1
Lau, CC1
Clos, TD1
Goebel, C1
Vogel, C1
Wulferink, M1
Mittmann, S1
Sachs, B1
Schraa, S1
Abel, J1
Degen, G1
Gleichmann, E1
Amano, K1
Takeuchi, T1
Mongey, AB1
Hess, E2
Salomon, DR1
Guerrero, RS1
Drayer, DE4
Jones, WN1
Trinca, CE1
Walson, PD1
Weiller, PJ2
Lammy, S1
Weiller, M1
Gabriel, B1
Sayag, J1
Mongin, M2
Novack, MA1
Paine, R2
Dubois, EL4
CHase, PH1
Henningsen, NC1
Cederberg, A1
Hanson, A1
Johansson, BW1
Warner, WA1
Carel, RS2
Shapiro, MS2
Shoham, D1
Gutman, A2
Kaplan, AI1
Zakher, F1
Sabin, S1
Cordoba, O1
Taragan, R1
Weisman, MH1
Shapiro, RF1
Bernstein, RE1
Lahita, R1
Kluger, J1
Koffler, D1
Sonnhag, C1
Karlsson, E1
Hed, J1
Foucar, E1
Erickson, DG1
Tung, KS1
Geltman, EM1
Gelfand, ML1
Kahn, MF3
Manicacci, M1
Segresta, JM1
Caulin, C1
Montagne, A2
Weiss, RB1
Simpson, PB1
Oppenheim, RC1
Oka, M1
Räsänen, J1
Häkkinen, P1
Pinnas, JL1
Dandavino, R1
Bach, JF1
Nies, AS1
Carr, K1
Oates, JA1
Stec, GP1
Lertora, JJ1
Atkinson, AJ1
Nevin, MJ1
Kushner, W1
Jones, C1
Schmid, FR1
Askenazi, J1
Homma, M1
Michalevicz, R1
Many, A1
Ramot, B1
McLain, DA1
Hahn, BH1
Hoff, BH1
Zech, P2
Colon, S1
Labeeuw, M1
Bernheim, J1
Blanc-Brunat, N1
Schwarz, JA1
Sahenk, Z1
Mendell, JR1
Rossio, JL1
Hurtubise, P1
Goldman, P1
Ingelfinger, JA1
Robinson, HM1
Nick, J1
Combrisson, A1
Reignier, A1
Verdy, E1
Gally, AM1
Bakouche, P1
Dudognon, P1
Dray, C1
Davis, S1
Furie, BC1
Griffin, JH1
Furie, B1
Willey, R1
Wierzchowiecki, M1
Rybicka, K1
Whittle, TS1
Ainsworth, SK1
Rao, KV1
Diaz, R1
Quigley, TJ1
Schubothe, H1
Maas, D1
Bell, WR1
Boss, GR1
Wolfson, JS1
Levo, Y1
Pick, AI1
Avidor, I1
Ben-Bassat, M1
Cohmen, G1
Ghose, MK1
Sunder, SK1
Shah, A1
Falko, JM1
Thomas, FB1
Utsinger, PD1
Stevens, MB2
Zacharias, W1
Koopman, WJ1
Gohill, J3
Smith, PR1
Nacht, RI1
Sim, E2
Sheikh, S1
Seggev, JS1
Abu-Shakra, M1
Shoenfeld, Y2
Arndt, RE1
Kotzin, BL1
Craft, JE1
Radding, JA1
Harding, MW1
Bernstein, RM1
Hardin, JA1
Clyne, LP1
Farber, LR1
Chopyk, RL1
Asherson, RA1
Zulman, J1
Hughes, GR1
Sanders, CE1
Budinsky, RA1
Meisner, DJ1
Carlson, RJ1
Gottlieb, AJ1
Vivino, FB1
Schumacher, HR1
Mohindra, SK1
Udeani, GO1
Abrahamson, D1
Ninos, NP1
Tomura, T1
van Lancker, JL1
Lovisetto, P1
Mairano, D1
Cargnino, M1
Biarese, V1
Marchi, L1
Lerda, R1
Agudelo, CA1
Wise, CM1
Lyles, MF1
Forrester, J1
Golbus, J1
Brede, D1
Hudson, J1
Chan, EK2
Sullivan, KF1
Kucharz, EJ1
Nishikai, M1
Sugimoto, M1
Sato, A1
Honda, M1
Naito, M1
Nagoshi, H1
Weisbart, RH1
Yee, WS1
Colburn, KK1
Whang, SH1
Heng, MK1
Boucek, RJ1
Vilner, Y1
Reshef, T1
Skibin, A1
Kooperman, O1
Kennedy, RC1
Nusinow, SR2
Rubenson, DS1
Curd, JG1
Vitas, B1
Eror, L1
Muhvić, R1
Pozar, B1
Polović, A1
Thomas, TJ1
Messner, RP1
Tang, FL1
Pollard, KM1
Tsay, G1
Harlé, JR1
Weiller, C1
Durand, JM1
Francoeur, AM1
Robinson, CA1
Epstein, A1
Barland, P1
Gorsulowsky, DC1
Bank, PW1
Goldberg, AD1
Lee, TG1
Heinzerling, RH1
Burnham, TK1
Kale, SA1
Cush, JJ1
Goldings, EA1
Amadio, P1
Cummings, DM1
Dashow, L1
McCormack, GD1
Barth, WF1
Hopkins, BE1
Whittingham, S2
Mackay, IR2
Camin-Belsky, N1
Kimchi, A1
Ben-Efraim, S2
Golochevskaia, VS1
Strain, L1
Rasmussen, K1
Hope, RR1
Bates, LA1
Dorfmann, H2
de Sèze, S2
Farkas, R1
Peltier, AP1
Estes, D1
Blumenkrantz, N1
Asboe-Hansen, G1
Ullman, S1
Wiik, A1
Kobayasi, T1
Halberg, P1
Harpey, JP1
McEwen, J1
Losada, M1
Meruane, J1
Carabia, AG1
Fortney, TG1
Fakhro, AM1
Ritchie, RF1
Lown, B1
Lappat, EJ1
Cawein, MJ1
Atkins, CJ1
Hamilton, EB1
Blomgren, SE3
Bignall, MC1
Vaughan, JH2
Günther, R1
Asamer, H1
Dittrich, P1
Waagstein, F1
Sheldon, PJ1
Williams, WR1
Cohen, AI1
Ehrlich, L1
Eldredge, NT1
van Robertson, WB1
Jiller, JJ1
Auerbach, RC1
Snyder, NE1
Bragg, DG1
Tuffanelli, DL2
Lambert, PH1
Creighton, D1
Goodman, R1
Bankhurst, A1
Mischer, PA1
Manigand, G1
Foulon, D1
Perrigot, M1
Deparis, M1
Lee, MM1
Frislid, K1
Hansteen, V1
Hart, FD1
Swarbrick, ET2
Gray, IR2
Bareis, RJ1
Anastassiades, TP1
Miliiken, JA1
Whitworth, JA1
Sloman, G1
Sokol, SA1
Winkler, JW1
Eberl, R1
Altmann, H1
Klein, W1
ten Veen, JH2
Feltkamp, TE1
Monson, RA1
Kewitz, H1
de la Baart Faille-Kuyper, EH1
Grossman, J1
Callerame, ML1
Durand, JP1
Simonin, JL1
Deshayes, P1
Taleb, N1
Mamo, A1
Ghorra, F1
Hannouche, G1
Uthman, SM1
Tabbara, RA1
Artinian, B1
Reesal, M1
Galea, G1
Geavlete, A1
Alarcón-Segovia, D1
Baker, H1
Moore-Robinson, M1
Puech, P1
Latour, H1
Hertault, J1
Grolleau, R1
Balmes, P1
Robert, M1
Tojo, T1
Friou, GJ1
Spiegelberg, HL1
Maxon, HR1
Zipes, DP1
Donlan, CJ1
Forker, AD1
Györkey, F1
Sinkovics, JG1
Min, KW1
Györkey, P1
Anderson, RJ1
Genton, E1
Levine, HD1
Rutherford, BD1
Wehr, KL1
Watts, E1
Russel, AS1
Ziff, M2
Habberstad, J1
Heymans, G1
Tenzer, C1
Dabrowska, B2
Lapińska, K2
Blaszczyk, M2
van de Merwe, JP1
Sawaya, J1
Hunt, WH1
Fries, D1
Brunat, N1
Bouletreau, P1
Traeger, J1
Petersen, BN1
Kok-Jensen, A1
Russell, AS1
Byrd, RB1
Schanzer, B1
Prockop, LD1
Paul, O1
Leigh, CG1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Monitoring the IMmUological TOXicity of Drugs[NCT03480529]662 participants (Actual)Observational [Patient Registry]2018-03-01Completed
Fasting Hypoglycemia: Diagnosis and Treatment[NCT00001276]1,500 participants (Anticipated)Observational1991-05-21Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

45 reviews available for procainamide and Lupus Erythematosus, Systemic

ArticleYear
Drug-induced lupus erythematosus: an update on drugs and mechanisms.
    Current opinion in rheumatology, 2018, Volume: 30, Issue:5

    Topics: Autoimmunity; Genetic Predisposition to Disease; Humans; Hydralazine; Immunologic Factors; Lupus Ery

2018
Mechanistic Insights of Chemicals and Drugs as Risk Factors for Systemic Lupus Erythematosus.
    Current medicinal chemistry, 2020, Volume: 27, Issue:31

    Topics: Autoimmune Diseases; Female; Humans; Hydralazine; Lupus Erythematosus, Systemic; Procainamide; Risk

2020
Drug-induced lupus erythematosus.
    Archives of dermatological research, 2009, Volume: 301, Issue:1

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Arrhythmia Agents; Antibodies; Antifungal Ag

2009
Drug-induced lupus: an update on its dermatologic aspects.
    Lupus, 2009, Volume: 18, Issue:11

    Topics: Anti-Arrhythmia Agents; Anti-Bacterial Agents; Antihypertensive Agents; Antitubercular Agents; Autoa

2009
Drug-induced lupus: an update.
    Autoimmunity reviews, 2010, Volume: 10, Issue:1

    Topics: Anti-Arrhythmia Agents; Humans; Hydralazine; Lupus Erythematosus, Systemic; Procainamide; Tumor Necr

2010
DNA methylation and autoimmune disease.
    Clinical immunology (Orlando, Fla.), 2003, Volume: 109, Issue:1

    Topics: Animals; Autoimmune Diseases; Autoimmunity; Azacitidine; Cell Communication; DNA Methylation; Humans

2003
[Immunologic tests: Anti-histone antibodies].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 7

    Topics: Antibodies, Antinuclear; Biomarkers; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Techniq

2005
[Drug-induced pericarditis].
    Nihon rinsho. Japanese journal of clinical medicine, 2007, Sep-28, Volume: Suppl 5 Pt 2

    Topics: Adrenal Cortex Hormones; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Antineopla

2007
[Drug-induced lupus erythematosus].
    Nihon rinsho. Japanese journal of clinical medicine, 2007, Oct-28, Volume: 65 Suppl 8

    Topics: Anti-Arrhythmia Agents; Antihypertensive Agents; Drug-Related Side Effects and Adverse Reactions; Hu

2007
DNA methylation in T cells from idiopathic lupus and drug-induced lupus patients.
    Autoimmunity reviews, 2008, Volume: 7, Issue:5

    Topics: Autoantibodies; B-Lymphocytes; CD4-Positive T-Lymphocytes; Cytokines; Cytotoxicity, Immunologic; DNA

2008
Procainamide: clinical pharmacology and efficacy against ventricular arrhythmias.
    Annals of the New York Academy of Sciences, 1984, Volume: 432

    Topics: Acecainide; Administration, Oral; Animals; Arrhythmias, Cardiac; Electrocardiography; Heart; Humans;

1984
Drug-induced lupus: clinical and serological studies.
    Clinics in rheumatic diseases, 1982, Volume: 8, Issue:1

    Topics: Acetyltransferases; Adult; Antibodies, Antinuclear; Anticonvulsants; Arthritis; Chlorpromazine; Cros

1982
Drug-induced systemic lupus erythematosus.
    Progress in clinical immunology, 1980, Volume: 4

    Topics: Antibodies, Antinuclear; Anticonvulsants; Chlorpromazine; Humans; Hydralazine; Isoniazid; Lupus Eryt

1980
DNA antibodies in systemic lupus erythematosus and pseudolupus syndrome.
    Advances in internal medicine, 1980, Volume: 26

    Topics: Animals; Antibodies; Antibody Specificity; Antigen-Antibody Complex; Counterimmunoelectrophoresis; C

1980
Drug-induced lupus: an adjuvant disease?
    The American journal of medicine, 1981, Volume: 71, Issue:1

    Topics: Adjuvants, Immunologic; Animals; Autoimmune Diseases; Humans; Hydralazine; Lupus Erythematosus, Syst

1981
Role of T cell DNA methylation in lupus syndromes.
    Lupus, 1994, Volume: 3, Issue:6

    Topics: Azacitidine; DNA; Humans; Lupus Erythematosus, Systemic; Lymphocyte Function-Associated Antigen-1; M

1994
Quinidine-induced rheumatic syndromes.
    Seminars in arthritis and rheumatism, 1995, Volume: 24, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Antinuclear; Atrial Fibrillation; Child; Diagnosis, Diff

1995
Procainamide-induced lupus in the elderly.
    Hospital practice (Office ed.), 1993, Jun-15, Volume: 28, Issue:6

    Topics: Aged; Antibodies, Antinuclear; Diagnosis, Differential; Female; Humans; Lupus Erythematosus, Systemi

1993
Drug-induced lupus.
    Internal medicine (Tokyo, Japan), 1996, Volume: 35, Issue:7

    Topics: Antibodies, Antinuclear; Anticonvulsants; Ethosuximide; Female; Humans; Hydralazine; Lupus Erythemat

1996
[Drug-induced lupus erythematosus].
    Ryoikibetsu shokogun shirizu, 2000, Issue:31

    Topics: Autoimmunity; Diagnosis, Differential; Drug-Related Side Effects and Adverse Reactions; Humans; Hydr

2000
Serologic abnormalities in spontaneous and drug-induced systemic lupus erythematosus.
    The Journal of rheumatology, 1975, Volume: 2, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Antibodies, Anti-Idiotypic; Antibodies, Antinuclear; Anticonvulsants

1975
Drug-induced systemic lupus erythematosus: a critical review.
    Seminars in arthritis and rheumatism, 1975, Volume: 5, Issue:1

    Topics: Adult; Allopurinol; Anti-Arrhythmia Agents; Anticonvulsants; Antithyroid Agents; Antitubercular Agen

1975
Glomerulonephritis in procainamide induced lupus erythematosus: report of a case and review of the literature.
    Journal of clinical & laboratory immunology, 1979, Volume: 2, Issue:1

    Topics: Azathioprine; Biopsy; Glomerulonephritis; Humans; Kidney Glomerulus; Lupus Erythematosus, Systemic;

1979
[Antinuclear antibodies in connective tissue diseases (author's transl)].
    Ryumachi. [Rheumatism], 1978, Volume: 18, Issue:3

    Topics: Adolescent; Adult; Aged; Animals; Antibodies, Antinuclear; Antigen-Antibody Complex; Autoantigens; C

1978
Drug-induced immune complex disease.
    Biochemical Society transactions, 1991, Volume: 19, Issue:1

    Topics: Amino Acid Sequence; Antigen-Antibody Complex; Complement Activation; Complement C4; Humans; Hydrala

1991
Metabolism of drugs by activated leukocytes: implications for drug-induced lupus and other drug hypersensitivity reactions.
    Advances in experimental medicine and biology, 1991, Volume: 283

    Topics: Antibody Formation; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions; Humans;

1991
Human anti-DNA idiotype (16/6 idiotype): pathogenic role in autoimmunity.
    Human antibodies and hybridomas, 1990, Volume: 1, Issue:1

    Topics: Animals; Antibodies, Anti-Idiotypic; Antibodies, Antinuclear; Antibodies, Monoclonal; Autoantibodies

1990
Drug-induced immune-complex disease.
    Complement and inflammation, 1989, Volume: 6, Issue:2

    Topics: Humans; Hydralazine; Immune Complex Diseases; Isoniazid; Lupus Erythematosus, Systemic; Penicillamin

1989
[Drug-induced lupus].
    Recenti progressi in medicina, 1985, Volume: 76, Issue:2

    Topics: Acetylation; Adrenergic beta-Antagonists; Antibodies, Antinuclear; Anticonvulsants; B-Lymphocytes; D

1985
Pure red cell aplasia in procainamide induced systemic lupus erythematosus. Report and review of the literature.
    The Journal of rheumatology, 1988, Volume: 15, Issue:9

    Topics: Aged; Humans; Lupus Erythematosus, Systemic; Male; Procainamide; Red-Cell Aplasia, Pure

1988
Antinuclear antibodies (ANAs): diagnostically specific immune markers and clues toward the understanding of systemic autoimmunity.
    Clinical immunology and immunopathology, 1988, Volume: 47, Issue:2

    Topics: Antibodies, Antinuclear; Autoantigens; Autoimmune Diseases; Cell Nucleus; Connective Tissue Diseases

1988
[Pathogenesis of drug-induced collagenosis-like syndrome].
    Przeglad lekarski, 1987, Volume: 44, Issue:5

    Topics: Humans; Hydralazine; Lupus Erythematosus, Systemic; Procainamide

1987
Connective tissue disease in the elderly.
    Clinics in rheumatic diseases, 1986, Volume: 12, Issue:1

    Topics: Aged; Connective Tissue Diseases; Dermatomyositis; Female; Giant Cell Arteritis; Humans; Hydralazine

1986
Drug-induced systemic lupus erythematosus. Differentiating it from the real thing.
    Postgraduate medicine, 1985, Feb-15, Volume: 77, Issue:3

    Topics: Diagnosis, Differential; Female; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Male

1985
Drug-induced lupus: clinical spectrum and pathogenesis.
    The American journal of the medical sciences, 1985, Volume: 290, Issue:1

    Topics: Acetylation; Adult; Aged; Antibodies, Antinuclear; Antibody Specificity; Autoimmune Diseases; Black

1985
[Side effects of anti-arrhythmic agents].
    Klinicheskaia meditsina, 1971, Volume: 49, Issue:10

    Topics: 1-Propanol; Adrenal Cortex Hormones; Agranulocytosis; Anorexia Nervosa; Anti-Arrhythmia Agents; Anti

1971
Systemic lupus erythematosus.
    JAMA, 1973, Apr-30, Volume: 224, Issue:5 Suppl

    Topics: Antibodies, Antinuclear; Arthritis, Rheumatoid; Female; Hepatitis; Humans; Hydralazine; Immunoglobul

1973
[Iatrogenic lupus: present status of the problem. II. Physiopathology of induced lupus].
    La Nouvelle presse medicale, 1972, Dec-09, Volume: 1, Issue:44

    Topics: Animals; Antibodies, Antinuclear; Disease Models, Animal; DNA, Viral; Drug-Related Side Effects and

1972
Antinuclear antibodies.
    Pathobiology annual, 1972, Volume: 2

    Topics: Animals; Antibodies, Antinuclear; Antibody Formation; Arthritis, Rheumatoid; Autoantigens; Cytotoxic

1972
Lupus-like syndromes induced by drugs.
    Annals of allergy, 1974, Volume: 33, Issue:5

    Topics: Antibodies, Antinuclear; Antibody Formation; Arthritis, Rheumatoid; Chlorpromazine; DNA, Single-Stra

1974
[Generalized lupus erythematosus caused by methyl-phenyl-ethyl-hydantoin].
    Revista medica de Chile, 1967, Volume: 95, Issue:7

    Topics: Adult; Autoimmune Diseases; Female; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; M

1967
Lupus erythematosus.
    Archives of dermatology, 1972, Volume: 106, Issue:4

    Topics: Antibodies, Antinuclear; Contraceptives, Oral; DNA; Female; Fluorescent Antibody Technique; Humans;

1972
A primer of collagen disease.
    Minnesota medicine, 1974, Volume: 57, Issue:10

    Topics: Administration, Topical; Adult; Anti-Inflammatory Agents; Antibodies; Central Nervous System Disease

1974
Drug-induced lupus syndromes.
    Mayo Clinic proceedings, 1969, Volume: 44, Issue:9

    Topics: Antibodies, Antinuclear; Anticonvulsants; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Syste

1969
Procaine amide-induced systemic lupus erythematosus.
    The British journal of dermatology, 1970, Volume: 82, Issue:3

    Topics: Kidney Diseases; Lupus Erythematosus, Systemic; Lymph Nodes; Procainamide

1970

Trials

1 trial available for procainamide and Lupus Erythematosus, Systemic

ArticleYear
Anti-[(H2A/2B)-DNA]] IgG supports the diagnosis of procainamide-induced arthritis or pleuritis.
    Arthritis and rheumatism, 1999, Volume: 42, Issue:6

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Antibodies, Antinuclear; DNA; Enzyme-Linked Immunosorbent Assay

1999

Other Studies

240 other studies available for procainamide and Lupus Erythematosus, Systemic

ArticleYear
Drug-induced systemic lupus: revisiting the ever-changing spectrum of the disease using the WHO pharmacovigilance database.
    Annals of the rheumatic diseases, 2019, Volume: 78, Issue:4

    Topics: Adalimumab; Adult; Antirheumatic Agents; Databases, Factual; Etanercept; Female; Humans; Hydralazine

2019
Molecular organization of the non-bilayer phospholipid arrangements that induce an autoimmune disease resembling human lupus in mice.
    Molecular membrane biology, 2012, Volume: 29, Issue:2

    Topics: Animals; Antibodies; Antibodies, Monoclonal; Cardiolipins; Cattle; Chlorpromazine; Kidney Glomerulus

2012
Demethylation of ITGAL (CD11a) regulatory sequences in systemic lupus erythematosus.
    Arthritis and rheumatism, 2002, Volume: 46, Issue:5

    Topics: Adult; Autoimmunity; Azacitidine; Cells, Cultured; DNA Methylation; Enzyme Inhibitors; Female; Gene

2002
Hydralazine may induce autoimmunity by inhibiting extracellular signal-regulated kinase pathway signaling.
    Arthritis and rheumatism, 2003, Volume: 48, Issue:3

    Topics: Animals; Autoimmunity; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-

2003
Procainamide-induced lupus erythematosus.
    The New England journal of medicine, 1962, Dec-27, Volume: 267

    Topics: Humans; Lupus Erythematosus, Systemic; Procainamide

1962
SYSTEMIC LUPUS ERYTHEMATOSUS ASSOCIATED WITH PROCAINAMIDE THERAPY.
    Missouri medicine, 1964, Volume: 61

    Topics: Humans; Lupus Erythematosus, Systemic; Procainamide; Toxicology

1964
LUPUS-LIKE ILLNESS PRECIPITATED BY PROCAINAMIDE HYDROCHLORIDE.
    JAMA, 1965, May-10, Volume: 192

    Topics: Arrhythmias, Cardiac; Autoimmune Diseases; Coombs Test; Diagnosis; Digoxin; Drug Therapy; Geriatrics

1965
PROCAINAMIDE AND LUPUS ERYTHEMATOSUS.
    JAMA, 1965, May-10, Volume: 192

    Topics: Humans; Lupus Erythematosus, Systemic; Procainamide

1965
LUPUS-LIKE SYNDROME INDUCED BY PROCAINE AMIDE: ASSOCIATION WITH ANTI-DNA ANTIBODY.
    Archives of internal medicine, 1965, Volume: 115

    Topics: Antibodies; Antibodies, Anti-Idiotypic; Antibodies, Antinuclear; Diagnosis; DNA; Drug Hypersensitivi

1965
Overexpression of CD70 and overstimulation of IgG synthesis by lupus T cells and T cells treated with DNA methylation inhibitors.
    Arthritis and rheumatism, 2004, Volume: 50, Issue:6

    Topics: Adult; Aged; Antigens, CD; Azacitidine; B-Lymphocytes; CD27 Ligand; DNA Methylation; Enzyme Inhibito

2004
Demethylation of the same promoter sequence increases CD70 expression in lupus T cells and T cells treated with lupus-inducing drugs.
    Journal of immunology (Baltimore, Md. : 1950), 2005, May-15, Volume: 174, Issue:10

    Topics: 5' Flanking Region; Adult; Antigens, CD; Base Sequence; CD27 Ligand; Cells, Cultured; DNA Methylatio

2005
Quinidine and procainamide inhibit murine macrophage uptake of apoptotic and necrotic cells: a novel contributing mechanism of drug-induced-lupus.
    Apoptosis : an international journal on programmed cell death, 2005, Volume: 10, Issue:5

    Topics: Animals; Apoptosis; Flow Cytometry; Lupus Erythematosus, Systemic; Macrophages, Peritoneal; Mice; Mi

2005
Bilateral Mondor's disease.
    Archives of dermatology, 1967, Volume: 95, Issue:1

    Topics: Adult; Breast Diseases; Female; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Procainami

1967
Vasculitis following procaine amide therapy.
    The American journal of medicine, 1967, Volume: 42, Issue:4

    Topics: Autoimmune Diseases; Drug Hypersensitivity; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged

1967
Procainamide HCl-induced lupus syndrome in a child with myotonia congenita.
    American journal of diseases of children (1960), 1967, Volume: 113, Issue:4

    Topics: Child, Preschool; Female; Humans; Lupus Erythematosus, Systemic; Myotonia Congenita; Procainamide

1967
Lupus-like syndrome induced by procainamide.
    British medical journal, 1967, Sep-23, Volume: 3, Issue:5568

    Topics: Arrhythmias, Cardiac; Female; Humans; Lupus Erythematosus, Systemic; Middle Aged; Procainamide; Prop

1967
Systemic lupus erythematosus associated with procainamide.
    The British journal of clinical practice, 1967, Volume: 21, Issue:5

    Topics: Aged; Heart Block; Humans; Lupus Erythematosus, Systemic; Male; Myocardial Infarction; Procainamide

1967
The epidemiology of drug-induced systemic lupus erythematosus.
    Arthritis and rheumatism, 1967, Volume: 10, Issue:5

    Topics: Adolescent; Adult; Aged; Child; Epilepsy; Female; Heart Diseases; Humans; Hydralazine; Hypertension;

1967
Studies of autologous mixed lymphocyte reactions in patients with systemic lupus erythematosus.
    Pathology, 1983, Volume: 15, Issue:1

    Topics: Adult; Aged; Antibodies; DNA; Female; Humans; Immunosuppressive Agents; Liver Cirrhosis, Biliary; Lu

1983
Drug allergy--problems and strategies.
    The Journal of allergy and clinical immunology, 1984, Volume: 74, Issue:3 Pt 1

    Topics: Anaphylaxis; Anemia, Hemolytic; Antigen-Antibody Complex; Desensitization, Immunologic; Dose-Respons

1984
Procainamide, NAPA and systemic lupus.
    Circulation, 1980, Volume: 61, Issue:4

    Topics: Acecainide; Animals; Dogs; Humans; Lupus Erythematosus, Systemic; Procainamide

1980
Procainamide-induced lupus erythematosus pericarditis encountered during coronary bypass sugery.
    The American journal of medicine, 1980, Volume: 69, Issue:1

    Topics: Biopsy; Coronary Artery Bypass; Humans; Intraoperative Complications; Lupus Erythematosus, Systemic;

1980
Efficacy, plasma concentrations and adverse effects of a new sustained release procainamide preparation.
    The American journal of cardiology, 1980, Volume: 46, Issue:5

    Topics: Acecainide; Acetylation; Adult; Aged; Anti-Arrhythmia Agents; Antibodies, Antinuclear; Arrhythmias,

1980
Alter drug structure--avert induced lupus.
    JAMA, 1981, Oct-09, Volume: 246, Issue:15

    Topics: Acecainide; Arrhythmias, Cardiac; Female; Humans; Lupus Erythematosus, Systemic; Male; Procainamide;

1981
The chemical induction of systemic lupus erythematosus and lupus-like illnesses.
    Arthritis and rheumatism, 1981, Volume: 24, Issue:8

    Topics: Acecainide; Acetylation; Adult; Female; Humans; Hydralazine; Hydrazines; Isoniazid; Lupus Erythemato

1981
Procainamide-lymphocyte reactions. A possible explanation for drug-induced autoimmunity.
    Arthritis and rheumatism, 1981, Volume: 24, Issue:8

    Topics: Aged; Animals; Antibody-Producing Cells; Antilymphocyte Serum; Autoimmune Diseases; Epitopes; Female

1981
The implications of procainamide metabolism to its induction of lupus.
    Arthritis and rheumatism, 1981, Volume: 24, Issue:8

    Topics: Acecainide; Acetylation; Animals; Antibodies, Antinuclear; Antibody Formation; Humans; Hydroxylamine

1981
Studies on a circulating anticoagulant in procainamide-induced lupus erythematosus.
    Archives of internal medicine, 1981, Volume: 141, Issue:12

    Topics: Aged; Blood Coagulation; Blood Coagulation Tests; gamma-Globulins; Humans; Immunoglobulin M; Immunog

1981
Inhibition of Con A mitogenesis by serum from procainamide-treated patients and patients with systemic lupus erythematosus.
    Immunological communications, 1982, Volume: 11, Issue:1

    Topics: Acecainide; Antibodies; Binding, Competitive; Concanavalin A; Humans; Immunoglobulin G; In Vitro Tec

1982
Aromatic amines and the pathogenesis of lupus erythematosus.
    The American journal of medicine, 1983, Volume: 75, Issue:6

    Topics: Acecainide; Acetylation; Amines; Anti-Arrhythmia Agents; Humans; Hydrazines; Lupus Erythematosus, Sy

1983
Immune regulatory abnormalities produced by procainamide.
    The American journal of medicine, 1982, Volume: 73, Issue:4

    Topics: Adolescent; Adult; Aged; Antibodies, Antinuclear; Autoantibodies; Concanavalin A; DNA, Single-Strand

1982
Drug-induced rheumatic diseases.
    Comprehensive therapy, 1984, Volume: 10, Issue:8

    Topics: Adrenal Cortex Hormones; Anticonvulsants; Antineoplastic Agents; Diuretics; Gout; Heparin; Humans; H

1984
Reactive hypoglycemia and insulin autoantibodies in drug-induced lupus erythematosus.
    Annals of internal medicine, 1983, Volume: 99, Issue:2

    Topics: Aged; Autoantibodies; Autoimmune Diseases; Female; Glucose Tolerance Test; Humans; Hydralazine; Hypo

1983
Autoallergic reactions induced by procainamide.
    The Journal of allergy and clinical immunology, 1984, Volume: 74, Issue:4 Pt 2

    Topics: Acetylation; Antibodies, Antinuclear; Antibody Formation; Antibody Specificity; Autoantibodies; Auto

1984
The prevalence of antibodies to histones induced by procainamide in old people, in cancer patients, and in rheumatoid-like disease.
    Clinical immunology and immunopathology, 1983, Volume: 27, Issue:1

    Topics: Adolescent; Adult; Aged; Aging; Antibodies, Antinuclear; Arthritis; Female; Histones; Humans; Lupus

1983
Procainamide-induced lupus lung disease characterized by neutrophil alveolitis.
    The American journal of medicine, 1984, Volume: 76, Issue:1

    Topics: Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Neutrophils; Pneumonia; Procainamide; Pulm

1984
Accelerated constrictive pericarditis in procainamide-induced systemic lupus erythematosus.
    The American journal of cardiology, 1984, Jan-15, Volume: 53, Issue:2

    Topics: Cardiac Catheterization; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Pericarditis, Con

1984
[Drug-induced lupus erythematosus syndrome. Pathogenesis and relation to systemic lupus erythematosus].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1984, Mar-01, Volume: 39, Issue:5

    Topics: Diagnosis, Differential; Drug-Related Side Effects and Adverse Reactions; Humans; Hydralazine; Lupus

1984
Prekallikrein inhibition associated with the lupus anticoagulant: a mechanism of thrombosis.
    American journal of clinical pathology, 1982, Volume: 77, Issue:3

    Topics: Adolescent; Adult; Autoimmune Diseases; Blood Coagulation Factors; Female; Femoral Vein; Fibrinolysi

1982
Reticulocytopenic, coombs' positive anemia induced by procainamide.
    American journal of clinical pathology, 1983, Volume: 80, Issue:1

    Topics: Anemia, Hemolytic; Coombs Test; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Procainami

1983
Low-dose procainamide: low risk of complications with long-term use.
    Journal of the National Medical Association, 1983, Volume: 75, Issue:7

    Topics: Adult; Aged; Coronary Disease; Female; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Pro

1983
SLE: idiopathic or drug-induced?
    Geriatrics, 1980, Volume: 35, Issue:3

    Topics: Adult; Aged; Antibodies, Antinuclear; Autoantibodies; Central Nervous System Diseases; DNA; Drug-Rel

1980
Large dose procainamide therapy for ventricular tachyarrhythmia.
    The American journal of cardiology, 1980, Volume: 46, Issue:3

    Topics: Adult; Aged; Anorexia; Antibodies, Antinuclear; Arrhythmias, Cardiac; Dose-Response Relationship, Dr

1980
[Procainamide-induced lupus erythematosus].
    Harefuah, 1980, Oct-01, Volume: 99, Issue:7

    Topics: Adult; Aged; Antibodies, Antinuclear; Female; Humans; Lupus Erythematosus, Systemic; Male; Middle Ag

1980
Antinuclear antibodies related to acetylator phenotype in mice.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 213, Issue:3

    Topics: Acetylation; Acetyltransferases; Animals; Antibodies, Antinuclear; Female; Lupus Erythematosus, Syst

1980
Disopyramide and antinuclear antibodies.
    American heart journal, 1981, Volume: 101, Issue:5

    Topics: Adult; Aged; Antibodies, Antinuclear; Disopyramide; Female; Humans; Lupus Erythematosus, Systemic; M

1981
Drug effects on autoantibodies and immune complexes.
    Agents and actions. Supplements, 1980, Volume: 7

    Topics: Acetylation; Antibodies, Antinuclear; Antigen-Antibody Complex; Arthritis, Rheumatoid; Autoantibodie

1980
Pharmacokinetic studies on the drug-related lupus syndrome. Differences in antinuclear antibody development and drug-induced DNA damage in rapid and slow acetylator animal models.
    Arthritis and rheumatism, 1981, Volume: 24, Issue:8

    Topics: Acetylation; Animals; Antibodies, Antinuclear; Antibody Formation; Disease Models, Animal; DNA Repai

1981
Renal manifestations of drug-induced systemic lupus erythematosus.
    American journal of clinical pathology, 1981, Volume: 75, Issue:5

    Topics: Biopsy; Fluorescent Antibody Technique; Glomerulonephritis; Humans; Kidney; Lupus Erythematosus, Sys

1981
The role of histones as nuclear autoantigens in drug-related lupus erythematosus.
    Arthritis and rheumatism, 1981, Volume: 24, Issue:8

    Topics: Animals; Antibodies, Antinuclear; Antibody Formation; Antibody Specificity; Antigens; Autoantigens;

1981
Update on quinidine and procainamide.
    Angiology, 1982, Volume: 33, Issue:7

    Topics: Arrhythmias, Cardiac; Digestive System; Drug Interactions; Heart; Humans; Lupus Erythematosus, Syste

1982
Drug-related lupus.
    Arthritis and rheumatism, 1982, Volume: 25, Issue:7

    Topics: Humans; Hydralazine; Lupus Erythematosus, Systemic; Procainamide

1982
[Procainamide-induced lupus with circulating anticoagulant].
    La Nouvelle presse medicale, 1982, Sep-04, Volume: 11, Issue:34

    Topics: Blood Coagulation; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Procainamide

1982
Systemic lupus erythematosus during treatment with procainamide.
    Indian journal of dermatology, 1982, Volume: 27, Issue:3

    Topics: Female; Humans; Lupus Erythematosus, Systemic; Procainamide

1982
Drug history is important.
    Medical times, 1981, Volume: 109, Issue:2

    Topics: Adult; Female; Humans; Lupus Erythematosus, Systemic; Medical History Taking; Procainamide; Tachycar

1981
Introduction to drug-related lupus.
    Arthritis and rheumatism, 1981, Volume: 24, Issue:8

    Topics: Acetylation; Acetyltransferases; Animals; Anticonvulsants; Autoimmune Diseases; Child; Chlorpromazin

1981
Hapten immunology and allergic reactions in humans.
    Arthritis and rheumatism, 1981, Volume: 24, Issue:8

    Topics: Animals; Autoimmune Diseases; Carrier Proteins; Drug Hypersensitivity; Environmental Health; Haptens

1981
Procainamide-induced myositis.
    Journal of the neurological sciences, 1980, Volume: 45, Issue:1

    Topics: Aged; Humans; Lupus Erythematosus, Systemic; Male; Muscles; Myositis; Procainamide

1980
Mechanism of drug-induced lupus. I. Cloned Th2 cells modified with DNA methylation inhibitors in vitro cause autoimmunity in vivo.
    Journal of immunology (Baltimore, Md. : 1950), 1995, Mar-15, Volume: 154, Issue:6

    Topics: Animals; Autoantibodies; Azacitidine; Cell Line; Cytokines; Cytotoxicity, Immunologic; DNA; Enzyme-L

1995
Epitope mapping of histone 5 (H5) with systemic lupus erythematosus, procainamide-induced lupus and hydralazine-induced lupus sera.
    Molecular immunology, 1993, Volume: 30, Issue:8

    Topics: Amino Acid Sequence; Antibody Specificity; Autoantibodies; Blotting, Western; Epitopes; Histones; Hu

1993
Treating activated CD4+ T cells with either of two distinct DNA methyltransferase inhibitors, 5-azacytidine or procainamide, is sufficient to cause a lupus-like disease in syngeneic mice.
    The Journal of clinical investigation, 1993, Volume: 92, Issue:1

    Topics: Animals; Antigen-Presenting Cells; Azacitidine; CD4-Positive T-Lymphocytes; DNA (Cytosine-5-)-Methyl

1993
Arty-crafty fact of life?
    Human & experimental toxicology, 1995, Volume: 14, Issue:3

    Topics: Acetaminophen; Cytotoxins; Humans; Lupus Erythematosus, Systemic; Neutrophils; Pharmaceutical Prepar

1995
IgG but not other classes of anti-[(H2A-H2B)-DNA] is an early sign of procainamide-induced lupus.
    Journal of immunology (Baltimore, Md. : 1950), 1995, Mar-01, Volume: 154, Issue:5

    Topics: Antibodies, Antinuclear; Arrhythmias, Cardiac; B-Lymphocytes; DNA; Histones; Humans; Immunoglobulin

1995
Transformation of lupus-inducing drugs to cytotoxic products by activated neutrophils.
    Science (New York, N.Y.), 1994, Nov-04, Volume: 266, Issue:5186

    Topics: Animals; Biological Assay; Biotransformation; Cell Death; Chlorpromazine; Humans; Hydralazine; Hydro

1994
Antibodies to dsDNA in drug induced lupus erythematosus.
    The Journal of rheumatology, 1994, Volume: 21, Issue:3

    Topics: Antibodies, Antinuclear; Artifacts; DNA; Humans; Hydralazine; Lupus Erythematosus, Systemic; Nucleic

1994
Study of procainamide hapten-specific antibodies in rabbits and humans.
    International journal of immunopharmacology, 1993, Volume: 15, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Animals; Antibody Specificity; Autoantibodies; Collagen; Female; Hap

1993
[A case of primary antiphospholipid antibody syndrome associated with procainamide induced systemic lupus erythematosus].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1995, Oct-10, Volume: 84, Issue:10

    Topics: Aged; Anti-Arrhythmia Agents; Antibodies, Antiphospholipid; Antiphospholipid Syndrome; Female; Human

1995
Autoimmunity caused by disruption of central T cell tolerance. A murine model of drug-induced lupus.
    The Journal of clinical investigation, 1997, Apr-15, Volume: 99, Issue:8

    Topics: Adoptive Transfer; Animals; Antibodies, Antinuclear; Autoimmunity; Disease Models, Animal; Female; H

1997
A metabolite of the lupus-inducing drug procainamide prevents anergy induction in T cell clones.
    Journal of immunology (Baltimore, Md. : 1950), 1997, May-01, Volume: 158, Issue:9

    Topics: Animals; Clonal Anergy; Immune Tolerance; Lupus Erythematosus, Systemic; Lymphocyte Activation; Mice

1997
Mechanisms of drug-induced lupus. III. Sex-specific differences in T cell homing may explain increased disease severity in female mice.
    Arthritis and rheumatism, 1997, Volume: 40, Issue:7

    Topics: Adoptive Transfer; Animals; Antibodies, Antinuclear; Autoantibodies; Autoimmune Diseases; Chemical a

1997
[Procainamide-induced lupus in a patient with bilateral pleural effusion].
    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 1998, Volume: 36, Issue:6

    Topics: Aged; Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Autoantibodies; Enzyme-Linked Immunosorbent

1998
Rapid development of drug-induced lupus nephritis in the absence of extrarenal disease in a patient receiving procainamide.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1998, Volume: 32, Issue:4

    Topics: Aged; Anti-Arrhythmia Agents; Biopsy; Diagnosis, Differential; Humans; Kidney; Lupus Erythematosus,

1998
Systemic sclerosis complicated by procainamide-induced lupus and antiphospholipid syndrome.
    British journal of rheumatology, 1998, Volume: 37, Issue:11

    Topics: Anti-Arrhythmia Agents; Antiphospholipid Syndrome; Arrhythmias, Cardiac; Foot Diseases; Gangrene; Hu

1998
Procainamide, a drug causing lupus, induces prostaglandin H synthase-2 and formation of T cell-sensitizing drug metabolites in mouse macrophages.
    Chemical research in toxicology, 1999, Volume: 12, Issue:6

    Topics: Animals; Arylamine N-Acetyltransferase; Enzyme Induction; Female; Isoenzymes; Lupus Erythematosus, S

1999
In vitro production of antibodies to histones in patients receiving chronic procainamide therapy.
    The Journal of rheumatology, 2001, Volume: 28, Issue:9

    Topics: Adult; Aged; Antibodies, Antinuclear; Arrhythmias, Cardiac; Autoantibodies; Autoimmunity; Cells, Cul

2001
Thymus function in drug-induced lupus.
    Lupus, 2001, Volume: 10, Issue:11

    Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Autoantibodies; Base Sequence; Chromatin; Female

2001
Clinical consequences of polymorphic acetylation of basic drugs.
    Clinical pharmacology and therapeutics, 1977, Volume: 22, Issue:3

    Topics: Acetylation; Antibodies, Antinuclear; Biotransformation; Chemical and Drug Induced Liver Injury; Hum

1977
Drug-induced systemic lupus erythematosus.
    Arizona medicine, 1978, Volume: 35, Issue:1

    Topics: Anticonvulsants; Antihypertensive Agents; Antipsychotic Agents; Antitubercular Agents; Female; Human

1978
[Lupos erythematosus discovered during the course of a toxicodermia (author's transl)].
    Annales de medecine interne, 1979, Volume: 130, Issue:12

    Topics: Adult; Aged; Ampicillin; Aprindine; Drug Eruptions; Female; Humans; Lupus Erythematosus, Systemic; M

1979
Procainamide-induced lupus syndrome in siblings.
    JAMA, 1975, Jun-23, Volume: 232, Issue:12

    Topics: Aged; Antibodies, Antinuclear; Atrial Fibrillation; Bundle-Branch Block; Female; Humans; Lupus Eryth

1975
Effects of long-term treatment with procaine amide. A prospective study with special regard to ANF and SLE in fast and slow acetylators.
    Acta medica Scandinavica, 1975, Volume: 198, Issue:6

    Topics: Acetylation; Adult; Aged; Antibodies, Antinuclear; Arrhythmias, Cardiac; Female; Humans; Lupus Eryth

1975
Drug-induced lupus erythematosus.
    Arizona medicine, 1977, Volume: 34, Issue:3

    Topics: Aged; Antibodies, Antinuclear; Arrhythmias, Cardiac; Humans; Lupus Erythematosus, Systemic; Male; Ne

1977
Lupus erythematosus cells in pleural effusion: the initial manifestation of procainamide-induced lupus erythematosus.
    Chest, 1977, Volume: 72, Issue:5

    Topics: Antibodies, Antinuclear; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Myocardial Infarc

1977
Drug-induced lupus erythematosus with in vivo lupus erythematosus cells in pleural fluid.
    Chest, 1978, Volume: 73, Issue:6

    Topics: Aged; Humans; Lupus Erythematosus, Systemic; Male; Neutrophils; Pleural Effusion; Procainamide

1978
LE cells in pleural fluid.
    Arthritis and rheumatism, 1979, Volume: 22, Issue:8

    Topics: Aged; Female; Humans; Hydralazine; Lupus Erythematosus, Systemic; Neutrophils; Pleural Effusion; Pro

1979
Lymphocyte alteration by procainamide: relation to drug-induced lupus erythematosus syndrome.
    Lancet (London, England), 1979, Oct-20, Volume: 2, Issue:8147

    Topics: Aged; Antibodies, Antinuclear; Antilymphocyte Serum; Cell Membrane; Cytotoxicity, Immunologic; Human

1979
Procainamide, acetylprocainamide, and drug-induced lupus erythematosus.
    Lancet (London, England), 1979, Nov-17, Volume: 2, Issue:8151

    Topics: Acecainide; Humans; Immune Complex Diseases; Lupus Erythematosus, Systemic; Procainamide

1979
Antibodies to nuclear antigens in patients treated with procainamide or acetylprocainamide.
    The New England journal of medicine, 1979, Dec-20, Volume: 301, Issue:25

    Topics: Acecainide; Aged; Antibodies, Antinuclear; Antibody Formation; Cell Nucleus; DNA; DNA, Single-Strand

1979
Procainamide-induced lupus erythematosus-like syndrome in relation to acetylator phenotype and plasma levels of procainamide.
    Acta medica Scandinavica, 1979, Volume: 206, Issue:4

    Topics: Acecainide; Acetylation; Adult; Aged; Antibodies, Antinuclear; Female; Humans; Isoniazid; Lupus Eryt

1979
Procainamide-induced lupus.
    The Johns Hopkins medical journal, 1976, Volume: 138, Issue:6

    Topics: Aged; Arrhythmias, Cardiac; Cardiomegaly; Drainage; Drug Therapy, Combination; Factor XI Deficiency;

1976
Atypical lupus-like syndrome following prolonged pronestyl administration.
    Journal of the American Medical Women's Association (1972), 1975, Volume: 30, Issue:8

    Topics: Aged; Humans; Long-Term Care; Lupus Erythematosus, Systemic; Male; Procainamide

1975
[Clinical and immunological study of 2 homozygotic twins of which 1 had disseminated lupus erythematosus caused by procainamide].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1977, Nov-16, Volume: 53, Issue:39

    Topics: Aged; Autoimmune Diseases; Diseases in Twins; Female; Humans; Lupus Erythematosus, Systemic; Procain

1977
Drug-induced systemic lupus erythematosus.
    The West Virginia medical journal, 1977, Volume: 73, Issue:5

    Topics: Digoxin; Humans; Hydrochlorothiazide; Lupus Erythematosus, Systemic; Male; Middle Aged; Procainamide

1977
Phospholipid monolayers and systemic lupus erythematosus.
    The New Zealand medical journal, 1977, Jul-13, Volume: 86, Issue:591

    Topics: Anesthetics, Local; Humans; Lupus Erythematosus, Systemic; Procainamide; Pulmonary Surfactants; Surf

1977
[Procainamide- and quinidine-induced immunological changes].
    Duodecim; laaketieteellinen aikakauskirja, 1977, Volume: 93, Issue:3

    Topics: Antibodies, Antinuclear; Arrhythmias, Cardiac; Humans; Immunoglobulins; Lupus Erythematosus, Systemi

1977
ANA, DNA, and SLE.
    Arizona medicine, 1977, Volume: 31, Issue:4

    Topics: Animals; Antibodies, Antinuclear; Autoimmune Diseases; DNA; Humans; Hydralazine; Lupus Erythematosus

1977
[Disseminated lupus erythematosus: etiopathogenic factors].
    Annales de medecine interne, 1977, Volume: 128, Issue:1

    Topics: Animals; Antibodies; Autoantibodies; B-Lymphocytes; Female; Humans; Hydantoins; Hydralazine; Isoniaz

1977
Effect of acetylator phenotype on the rate at which procainamide induces antinuclear antibodies and the lupus syndrome.
    The New England journal of medicine, 1978, May-25, Volume: 298, Issue:21

    Topics: Acetylation; Adult; Aged; Antibodies, Antinuclear; Biotransformation; History, 18th Century; Humans;

1978
Remission of procainamide-induced lupus erythematosus with N-acetylprocainamide therapy.
    Annals of internal medicine, 1979, Volume: 90, Issue:5

    Topics: Antibodies, Antinuclear; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Procainamide

1979
Antibodies to histones in drug-induced and idiopathic lupus erythematosus.
    The Journal of clinical investigation, 1978, Volume: 62, Issue:3

    Topics: Antibodies, Antinuclear; Antibody Specificity; Cell Nucleus; Fluorescent Antibody Technique; Histone

1978
Peripheral blood lymphocytes in systemic lupus erythematosus. Relation to activity.
    Acta haematologica, 1977, Volume: 57, Issue:4

    Topics: Humans; Immunologic Techniques; Lupus Erythematosus, Systemic; Lymphocytes; Mephenytoin; Practolol;

1977
Cryoglobulins in the procainamide-induced lupus syndrome.
    Arthritis and rheumatism, 1979, Volume: 22, Issue:3

    Topics: Aged; Cryoglobulins; Humans; Lupus Erythematosus, Systemic; Male; Paraproteinemias; Procainamide

1979
Drug-induced lupus erythematosus.
    Chest, 1979, Volume: 75, Issue:1

    Topics: Complement System Proteins; Drug-Related Side Effects and Adverse Reactions; Humans; Lupus Erythemat

1979
Nephrotic syndrome in procainamide induced lupus nephritis.
    Clinical nephrology, 1979, Volume: 11, Issue:4

    Topics: Aged; Female; Humans; Kidney; Lupus Erythematosus, Systemic; Nephritis; Nephrotic Syndrome; Predniso

1979
[Drug-induced disorders of lupus erythematosus type (author's transl)].
    Arzneimittel-Forschung, 1977, Volume: 27, Issue:96

    Topics: Animals; Antibody Formation; Anticonvulsants; Chlorpromazine; Drug-Related Side Effects and Adverse

1977
Polyradiculoneuropathy accompanying procainamide-induced lupus erythematosus: evidence for drug-induced enhanced sensitization to peripheral nerve myelin.
    Annals of neurology, 1977, Volume: 1, Issue:4

    Topics: Aged; Angina Pectoris; Animals; Demyelinating Diseases; Drug Hypersensitivity; Humans; Lupus Erythem

1977
Therapy with antiarrhythmic drugs.
    The New England journal of medicine, 1978, May-25, Volume: 298, Issue:21

    Topics: Acetylation; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disopyramide; Heart Failure; Humans; Indo

1978
[New aspects of drug induced lupus erythematosus (author's transl)].
    Zeitschrift fur Hautkrankheiten, 1978, May-15, Volume: 53, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Allopurinol; Aspirin; Humans; Lupus Erythematosus, Systemic; M

1978
[Iatrogenic procaine amide-induced lupus with circulating anticoagulant].
    Annales de medecine interne, 1978, Volume: 129, Issue:4

    Topics: Aged; Blood Coagulation Disorders; Humans; In Vitro Techniques; Lupus Erythematosus, Systemic; Proca

1978
Circulating inhibitors of blood coagulation associated with procainamide-induced lupus erythematosus.
    American journal of hematology, 1978, Volume: 4, Issue:4

    Topics: Blood Coagulation; Blood Coagulation Factors; Blood Coagulation Tests; Factor X; Humans; Immunoglobu

1978
[Lupus erythematosus-like syndrome induced by long-term treatment with procainamide].
    Polskie Archiwum Medycyny Wewnetrznej, 1978, Volume: 59, Issue:2

    Topics: Arrhythmias, Cardiac; Diagnosis, Differential; Humans; Lupus Erythematosus, Systemic; Male; Middle A

1978
Procainamide-induced systemic lupus erythematosus. Renal involvement with deposition of immune complexes.
    Archives of pathology & laboratory medicine, 1976, Volume: 100, Issue:9

    Topics: Autoantibodies; Fluorescent Antibody Technique; Humans; Iatrogenic Disease; Kidney; Lupus Erythemato

1976
Procainamide-induced systemic lupus erythematosus with hypocomplementemia.
    Journal of the American Geriatrics Society, 1977, Volume: 25, Issue:5

    Topics: Aged; Complement System Proteins; Digoxin; Female; Humans; Lupus Erythematosus, Systemic; Prednisone

1977
Lupus syndrome induced by procainamide.
    Medical times, 1977, Volume: 105, Issue:8

    Topics: Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Procainamide

1977
[Drug-induced systemic lupus erythematosus (author's transl)].
    Immunitat und Infektion, 1977, Volume: 5, Issue:4

    Topics: Adolescent; Aged; Anti-Bacterial Agents; Antibody Formation; Autoantibodies; Child; Chlorpromazine;

1977
Circulating anticoagulant in the procainamide-induced lupus syndrome.
    Archives of internal medicine, 1977, Volume: 137, Issue:10

    Topics: Aged; Arrhythmias, Cardiac; Blood Coagulation; Diagnosis, Differential; Factor XI; Fibrin Fibrinogen

1977
Clinicopathological study of a patient with procainamide-induced systemic lupus erythematosus.
    Annals of the rheumatic diseases, 1976, Volume: 35, Issue:2

    Topics: Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Procainamide; Tachycardia, Paroxysmal

1976
[Drug-induced lupus erythematosus-like syndromes].
    Medizinische Klinik, 1976, May-07, Volume: 71, Issue:19

    Topics: Adolescent; Adult; Aged; Antibodies, Antinuclear; Anticonvulsants; Drug-Related Side Effects and Adv

1976
Pericardial tamponade. A presenting manifestation of procainamide-induced lupus erythematosus.
    The American journal of medicine, 1975, Volume: 58, Issue:4

    Topics: Aged; Cardiac Tamponade; Humans; Lupus Erythematosus, Systemic; Male; Pericardial Effusion; Pericard

1975
Constrictive pericarditis in procainamide-induced lupus erythematosus syndrome.
    The American journal of cardiology, 1975, Volume: 36, Issue:7

    Topics: Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Pericarditis, Constrictive; Prednisone; Pr

1975
Letter: Acute pancreatitis due to procainamide-induced lupus erythematosus.
    Annals of internal medicine, 1975, Volume: 83, Issue:6

    Topics: Acute Disease; Aged; Humans; Lupus Erythematosus, Systemic; Male; Pancreatitis; Procainamide

1975
Hypocomplementemia in procainamide-associated systemic lupus erythematosus.
    Annals of internal medicine, 1976, Volume: 84, Issue:3

    Topics: Antibodies; Complement System Proteins; DNA; Humans; Lupus Erythematosus, Systemic; Male; Middle Age

1976
Drug-induced lupus.
    Hospital practice (Office ed.), 1992, Mar-30, Volume: 27, Issue:3A

    Topics: Acebutolol; Adult; Aged; Antibodies, Antinuclear; Blood Sedimentation; Female; Humans; Lupus Erythem

1992
Autoantibody specificity in drug-induced lupus and neutrophil-mediated metabolism of lupus-inducing drugs.
    Clinical biochemistry, 1992, Volume: 25, Issue:3

    Topics: Antibody Specificity; Autoantibodies; Chromatin; Histones; Humans; Hydralazine; Lupus Erythematosus,

1992
Lupus-inducing drugs alter the structure of supercoiled circular DNA domains.
    Arthritis and rheumatism, 1990, Volume: 33, Issue:3

    Topics: Acecainide; Animals; Antibodies; Canavanine; DNA, Superhelical; Electrophoresis, Agar Gel; Escherich

1990
Antibodies from patients with systemic lupus erythematosus and drug-induced lupus bind determinants on histone 5 (H5).
    Molecular immunology, 1990, Volume: 27, Issue:8

    Topics: Amino Acid Sequence; Animals; Autoantibodies; Chickens; Cross Reactions; Epitopes; Histones; Humans;

1990
Drug-induced lupus pleuritis mimicking pleural space infection.
    Chest, 1992, Volume: 101, Issue:1

    Topics: Acute Disease; Aged; Diagnosis, Differential; Humans; Infections; Lupus Erythematosus, Systemic; Mal

1992
Procainamide-induced pleural fibrosis.
    The American journal of medicine, 1991, Volume: 91, Issue:3

    Topics: Aged; Fibrosis; Humans; Lupus Erythematosus, Systemic; Male; Pleura; Procainamide

1991
Purification of histone H1 polypeptides by high-performance cation-exchange chromatography.
    Journal of chromatography, 1990, Feb-21, Volume: 502, Issue:1

    Topics: Animals; Bromosuccinimide; Cattle; Chromatography, Liquid; Chymotrypsin; Enzyme-Linked Immunosorbent

1990
Anti-histone antibodies in idiopathic and drug-induced lupus recognize distinct intrahistone regions.
    Journal of immunology (Baltimore, Md. : 1950), 1987, Jan-15, Volume: 138, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Autoantibodies; Epitopes; Histones; Humans; H

1987
Procainamide, N-acetylprocainamide, antinuclear antibody and systemic lupus erythematosus.
    Angiology, 1986, Volume: 37, Issue:12 Pt 2

    Topics: Acecainide; Acetylation; Antibodies, Antinuclear; Humans; Lupus Erythematosus, Systemic; Procainamid

1986
Autoantigenic histone epitopes: a comparison between procainamide- and hydralazine-induced lupus.
    Arthritis and rheumatism, 1987, Volume: 30, Issue:6

    Topics: Autoantigens; Epitopes; Histones; Humans; Hydralazine; Lupus Erythematosus, Systemic; Procainamide

1987
Procainamide-induced circulating anticoagulants in a congenitally-deficient factor XI patient.
    Folia haematologica (Leipzig, Germany : 1928), 1989, Volume: 116, Issue:2

    Topics: Aged; Blood Coagulation Factors; Blood Coagulation Tests; Coronary Artery Bypass; Factor XI Deficien

1989
Pulmonary thromboembolism associated with procainamide induced lupus syndrome and anticardiolipin antibodies.
    Annals of the rheumatic diseases, 1989, Volume: 48, Issue:3

    Topics: Aged; Autoantibodies; Blood Coagulation Factors; Cardiolipins; Humans; Lupus Coagulation Inhibitor;

1989
Immunomodulatory effects of procainamide metabolites: their implications in drug-related lupus.
    The Journal of laboratory and clinical medicine, 1989, Volume: 113, Issue:4

    Topics: Adult; Female; Hemoglobins; Humans; Immunoglobulins; Interleukin-1; Latex; Leukocytes, Mononuclear;

1989
Thrombocytopenia following sustained-release procainamide.
    Archives of internal medicine, 1985, Volume: 145, Issue:4

    Topics: Acecainide; Acetylation; Adult; Aged; Antibodies, Antinuclear; Delayed-Action Preparations; Humans;

1985
Synovial fluid characteristics and the lupus erythematosus cell phenomenon in drug-induced lupus. Findings in three patients and review of pertinent literature.
    Arthritis and rheumatism, 1989, Volume: 32, Issue:5

    Topics: Adult; Aged; Female; Humans; Lupus Erythematosus, Systemic; Male; Mephenytoin; Middle Aged; Procaina

1989
Cardiac tamponade associated with drug-induced systemic lupus erythematosus.
    Critical care medicine, 1989, Volume: 17, Issue:9

    Topics: Cardiac Tamponade; Female; Humans; Lupus Erythematosus, Systemic; Middle Aged; Procainamide

1989
Seek and find.
    Critical care medicine, 1989, Volume: 17, Issue:9

    Topics: Cardiac Tamponade; Humans; Lupus Erythematosus, Systemic; Procainamide

1989
Procainamide-DNA interaction.
    The Journal of rheumatology, 1988, Volume: 15, Issue:1

    Topics: Animals; Darkness; DNA; DNA Damage; DNA Polymerase I; DNA Repair; Endonucleases; Light; Lupus Erythe

1988
Association of antibody to histone complex H2A-H2B with symptomatic procainamide-induced lupus.
    The New England journal of medicine, 1988, Jun-02, Volume: 318, Issue:22

    Topics: Aged; Aged, 80 and over; Antibodies, Antinuclear; Cardiolipins; Enzyme-Linked Immunosorbent Assay; F

1988
Drug-related lupus.
    The New England journal of medicine, 1988, Jun-02, Volume: 318, Issue:22

    Topics: Antibodies, Antinuclear; Histones; Humans; Lupus Erythematosus, Systemic; Procainamide

1988
Drug-induced lupus.
    Journal of the Tennessee Medical Association, 1988, Volume: 81, Issue:9

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Antinuclear; Humans; Lupus Erythematosus,

1988
B cell activation in patients with active procainamide induced lupus.
    The Journal of rheumatology, 1988, Volume: 15, Issue:9

    Topics: Aged; B-Lymphocytes; Cells, Cultured; Female; Humans; Lupus Erythematosus, Systemic; Lymphocyte Acti

1988
Antibodies in procainamide-induced and systemic lupus erythematosus bind the C-terminus of histone 1 (H1).
    Molecular immunology, 1987, Volume: 24, Issue:3

    Topics: Amino Acids; Antibodies, Antinuclear; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbe

1987
[Procainamide- and hydralazine-induced antinuclear antibodies in Japanese].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1987, Volume: 76, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Antinuclear; Asian People; Female; Humans; Hydralazine;

1987
Antiguanosine antibodies: a new marker for procainamide-induced systemic lupus erythematosus.
    Annals of internal medicine, 1986, Volume: 104, Issue:3

    Topics: Adult; Aged; Antibodies, Antinuclear; DNA, Single-Stranded; Female; Fluorescent Antibody Technique;

1986
Increased presence of common systemic lupus erythematosus (SLE) anti-DNA idiotypes (16/6 Id, 32/15 Id) is induced by procainamide.
    Journal of clinical immunology, 1987, Volume: 7, Issue:5

    Topics: Antibodies, Viral; Antibody Formation; Antigen-Antibody Complex; DNA; Enzyme-Linked Immunosorbent As

1987
Serologic changes during induction of lupus-like disease by procainamide.
    The American journal of medicine, 1986, Volume: 80, Issue:5

    Topics: Aged; Antibodies; Complement Activation; Histones; Humans; Lupus Erythematosus, Systemic; Male; Panc

1986
[A erythematosus-like syndrome caused by procainamide].
    Lijecnicki vjesnik, 1986, Volume: 108, Issue:4

    Topics: Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Procainamide

1986
Effects of lupus-inducing drugs on the B to Z transition of synthetic DNA.
    Arthritis and rheumatism, 1986, Volume: 29, Issue:5

    Topics: Canavanine; Circular Dichroism; DNA; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Nucleic

1986
IgG subclasses of autoantibodies in systemic lupus erythematosus, Sjogren's syndrome, and drug-induced autoimmunity.
    Journal of immunology (Baltimore, Md. : 1950), 1986, Oct-15, Volume: 137, Issue:8

    Topics: Antibodies, Monoclonal; Autoantibodies; Autoimmune Diseases; DNA; Enzyme-Linked Immunosorbent Assay;

1986
[Systemic lupus erythematosus diagnosed after 12 years' treatment with procainamide].
    Annales de medecine interne, 1986, Volume: 137, Issue:7

    Topics: Female; Humans; Lupus Erythematosus, Systemic; Middle Aged; Procainamide; Time Factors

1986
Anti-histones.
    Scandinavian journal of rheumatology. Supplement, 1985, Volume: 56

    Topics: Antibodies, Monoclonal; Arthritis, Rheumatoid; Autoantibodies; Binding Sites, Antibody; Binding, Com

1985
IgG antibodies to the histone complex H2A-H2B characterize procainamide-induced lupus.
    Clinical immunology and immunopathology, 1985, Volume: 36, Issue:1

    Topics: Adult; Aged; Antibodies, Anti-Idiotypic; Antibody Specificity; Autoantibodies; Female; Histones; Hum

1985
Drug-induced lupus. Genetic, clinical, and laboratory features.
    Postgraduate medicine, 1985, Sep-01, Volume: 78, Issue:3

    Topics: Aged; Antibodies, Antinuclear; Diagnosis, Differential; Humans; Hydralazine; Immunoglobulins; Lupus

1985
The diagnostic value of antihistone antibodies in drug-induced lupus erythematosus.
    Arthritis and rheumatism, 1985, Volume: 28, Issue:2

    Topics: Adolescent; Adult; Aged; Antibodies, Antinuclear; Autoantibodies; Child; Disopyramide; Female; Fluor

1985
Antinuclear antibodies as indicators for the procainamide-induced systemic lupus erythematosus-like syndrome and its clinical presentations.
    Journal of the American Academy of Dermatology, 1985, Volume: 12, Issue:2 Pt 1

    Topics: Antibodies, Antinuclear; Antibody Specificity; Antigens; Antigens, Nuclear; Arrhythmias, Cardiac; De

1985
Procainamide, quinidine, and lupus erythematosus.
    Annals of internal medicine, 1985, Volume: 102, Issue:3

    Topics: Aged; Female; Humans; Lupus Erythematosus, Systemic; Procainamide; Quinidine

1985
Quinidine induced lupus syndrome.
    Seminars in arthritis and rheumatism, 1985, Volume: 15, Issue:1

    Topics: Aged; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Procainamide; Quinidine; Thrombocyto

1985
Procainamide-induced lupus-like syndrome.
    The Medical journal of Australia, 1970, Oct-17, Volume: 2, Issue:16

    Topics: Aged; Antibodies, Antinuclear; Arrhythmias, Cardiac; Female; Humans; Lupus Erythematosus, Systemic;

1970
Systemic lupus erythematosus induced by procaine amide.
    Australasian annals of medicine, 1970, Volume: 19, Issue:4

    Topics: Aged; Antibodies, Antinuclear; Arrhythmias, Cardiac; Blood Proteins; Blood Sedimentation; Humans; Im

1970
Occurrence, immunoglobulin pattern and specificity of antinuclear antibodies in sera of procaine amide treated patients.
    Clinical and experimental immunology, 1970, Volume: 7, Issue:5

    Topics: Adolescent; Adult; Aged; Antibodies, Antinuclear; Antibody Formation; Arrhythmias, Cardiac; Coronary

1970
Failure of procainamide to induce a systemic lupus erythematosus-like disease in animals.
    Toxicology and applied pharmacology, 1972, Volume: 21, Issue:2

    Topics: Animals; Antibodies, Antinuclear; Blood Cell Count; Blood Volume Determination; Body Weight; Criceti

1972
[Drug-induced lupus erythematosus disseminatus].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1972, Apr-10, Volume: 92, Issue:10

    Topics: Anti-Arrhythmia Agents; Anti-Bacterial Agents; Anti-Inflammatory Agents; Anticonvulsants; Antihypert

1972
The frequency of procainamide-induced systemic lupus erythematosus.
    The Medical journal of Australia, 1972, Aug-05, Volume: 2, Issue:6

    Topics: Adult; Aged; Antibodies, Antinuclear; Arrhythmias, Cardiac; Coombs Test; Female; Hemagglutination Te

1972
Current status of the LE cell test.
    Seminars in arthritis and rheumatism, 1971, Volume: 1, Issue:2

    Topics: Animals; Antibodies, Antinuclear; Complement System Proteins; Guinea Pigs; Humans; Immunoglobulin G;

1971
Complement-fixing activity of antinuclear antibodies induced by procaine amide treatment.
    Israel journal of medical sciences, 1973, Volume: 9, Issue:5

    Topics: Animals; Antibodies, Antinuclear; Cattle; Complement Fixation Tests; Complement System Proteins; Flu

1973
Connective-tissue effects of drugs causing lupoid syndrome.
    Acta dermato-venereologica, 1974, Volume: 54, Issue:1

    Topics: Animals; Carbon Radioisotopes; Chick Embryo; Chlorpromazine; Collagen; Depression, Chemical; Glucosa

1974
Drug-induced autoimmune disease.
    Federation proceedings, 1974, Volume: 33, Issue:8

    Topics: Acetyltransferases; Antibodies, Antinuclear; Antibody Specificity; Autoimmune Diseases; Binding Site

1974
Drug-induced lupus erythematosus syndrome. Immuno-pathological, electronmicroscopical and serological studies.
    Acta dermato-venereologica, 1974, Volume: 54, Issue:5

    Topics: Adult; Animals; Antibodies, Antinuclear; Biopsy; Complement Fixation Tests; Female; Fluorescent Anti

1974
Letter: Aetiology of systemic lupus erythematosus.
    Lancet (London, England), 1974, Dec-28, Volume: 2, Issue:7896

    Topics: Acetylation; Antibody Formation; DNA; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic;

1974
Case report: lupus-like syndrome with positive Hargrave phenomenon induced by pronestyl therapy: analysis of the test.
    Journal of the Tennessee Medical Association, 1965, Volume: 58, Issue:9

    Topics: Diagnosis, Differential; Female; Humans; Lupus Erythematosus, Systemic; Middle Aged; Neutrophils; Pr

1965
Procainamide hydrochloride and lupus erythematosus.
    JAMA, 1965, Oct-04, Volume: 194, Issue:1

    Topics: Aged; Dexamethasone; Diagnosis, Differential; Electrocardiography; Female; Humans; Joint Diseases; L

1965
Lupus-like syndrome induced by procainamide.
    The American journal of cardiology, 1967, Volume: 20, Issue:3

    Topics: Adult; Aged; Antibodies, Antinuclear; Atrial Fibrillation; Atrial Flutter; Autoantibodies; Fluoresce

1967
A familial study of procainamide-induced systemic lupus erythematosus. A question of pharmacogenetic polymorphism.
    The American journal of medicine, 1968, Volume: 45, Issue:6

    Topics: Antibodies, Antinuclear; Arthritis; Autoantibodies; Female; Fluorescent Antibody Technique; Humans;

1968
Procainamide-induced systemic lupus erythematosus.
    Proceedings of the Royal Society of Medicine, 1969, Volume: 62, Issue:2

    Topics: Antibodies, Antinuclear; Female; Humans; Lupus Erythematosus, Systemic; Middle Aged; Neutrophils; Pr

1969
Antinuclear antibody induced by procainamide. A prospective study.
    The New England journal of medicine, 1969, Jul-10, Volume: 281, Issue:2

    Topics: Adult; Aged; Antibodies, Antinuclear; Arrhythmias, Cardiac; Autoantibodies; Complement System Protei

1969
[The reversible procaine amide-induced lupus-erythromatosus syndrome].
    Deutsche medizinische Wochenschrift (1946), 1969, Nov-07, Volume: 94, Issue:45

    Topics: Aged; Antibodies; Antibodies, Antinuclear; Biopsy; Corticosterone; Female; Histocytochemistry; Human

1969
[Procaine-induced lupus erythematosus].
    Nordisk medicin, 1970, Apr-09, Volume: 83, Issue:15

    Topics: Aged; Antibodies, Antinuclear; Arthritis; Blood Sedimentation; Female; Heart Diseases; Humans; Lupus

1970
Procainamide-induced systemic lupus erythematosus.
    Annals of the rheumatic diseases, 1970, Volume: 29, Issue:3

    Topics: Aged; Angina Pectoris; Antibodies, Anti-Idiotypic; Antibodies, Antinuclear; Arrhythmias, Cardiac; Bl

1970
Procainamide induced lupus diathesis.
    Arizona medicine, 1968, Volume: 25, Issue:6

    Topics: Adult; Aged; Cardiac Complexes, Premature; Humans; Lupus Erythematosus, Systemic; Male; Procainamide

1968
When a drug is the culprit.
    Geriatrics, 1973, Volume: 28, Issue:9

    Topics: Adult; Aged; Angina Pectoris; Arrhythmias, Cardiac; Clofibrate; Depression; Drug-Related Side Effect

1973
The interaction of lupus-inducing drugs with deoxyribonucleic acid.
    Clinical immunology and immunopathology, 1974, Volume: 3, Issue:2

    Topics: Adult; Animals; Cattle; Child; DNA; DNA, Single-Stranded; Hot Temperature; Humans; Hydralazine; Immu

1974
The chest roentgenographic manifestations of Pronestyl-induced lupus erythematosus.
    Radiology, 1973, Volume: 109, Issue:2

    Topics: Aged; Antibodies, Antinuclear; Arrhythmias, Cardiac; Cardiomegaly; Cardiomyopathies; Female; Heart;

1973
[Experimental approach to the pathogenesis of systemic lupus erythematosus].
    Journal d'urologie et de nephrologie, 1972, Volume: 78, Issue:12

    Topics: Animals; Antigen-Antibody Complex; Autoantibodies; Cyclophosphamide; Disease Models, Animal; DNA; Fe

1972
[Acute lupus erythematosus induced by procainamide].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1973, Nov-26, Volume: 49, Issue:48

    Topics: Age Factors; Antibodies, Antinuclear; Arthritis; Fever; Heart Diseases; Humans; Lupus Erythematosus,

1973
Morphologic effects of procaine amide on mouse kidney as observed by scanning and by transmission electron microscopy.
    Laboratory investigation; a journal of technical methods and pathology, 1974, Volume: 31, Issue:4

    Topics: Animals; Basement Membrane; Disease Models, Animal; Female; Kidney Glomerulus; Lupus Erythematosus,

1974
[Drug induced lupus erythematosus disseminatus syndrome].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1974, Oct-10, Volume: 94, Issue:28

    Topics: Female; Humans; Lupus Erythematosus, Systemic; Male; Procainamide; Registries

1974
Drug-induced arthritis.
    Current medical research and opinion, 1974, Volume: 2, Issue:9

    Topics: Acute Disease; Anticoagulants; Antihypertensive Agents; Arteritis; Arthritis; Barbiturates; Contrace

1974
Procainamide-induced systemic lupus erythematosus.
    Rheumatology and rehabilitation, 1973, Volume: 12, Issue:2

    Topics: Diagnosis, Differential; Feeding and Eating Disorders; Fever; Heart Diseases; Humans; Lupus Erythema

1973
Procainamide-induced lupus erythematosus.
    South Dakota journal of medicine, 1974, Volume: 27, Issue:3

    Topics: Aged; Arrhythmias, Cardiac; Female; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Procai

1974
Procainamide-induced lupus erythematosus. Clinical and laboratory observations.
    The American journal of medicine, 1972, Volume: 52, Issue:3

    Topics: Animals; Antibodies, Antinuclear; Antibody Formation; Autoimmune Diseases; Cattle; Complement Fixati

1972
Lupus-like syndrome, with persistent immunological abnormalities, related to procainamide therapy.
    Canadian Medical Association journal, 1972, Aug-19, Volume: 107, Issue:4

    Topics: Adult; Antibodies, Antinuclear; Blood Protein Electrophoresis; Female; Humans; Immune System Disease

1972
Antinuclear antibody response to procainamide in man and laboratory animals.
    American heart journal, 1972, Volume: 84, Issue:2

    Topics: Adult; Aged; Animals; Antibodies, Antinuclear; Antibody Formation; Female; Guinea Pigs; Humans; Lupu

1972
[Iatrogenic lupus: current status of the question. I. Clinical study and main drugs responsible].
    La Nouvelle presse medicale, 1972, Dec-02, Volume: 1, Issue:43

    Topics: Antibodies, Antinuclear; Contraceptives, Oral; Diagnosis, Differential; Humans; Hydralazine; Iatroge

1972
Procainamide and lupus erythematosus.
    The Journal of the Maine Medical Association, 1973, Volume: 64, Issue:3

    Topics: Adult; Aged; Antibodies, Antinuclear; Female; Humans; Lupus Erythematosus, Systemic; Male; Middle Ag

1973
Drug-induced pulmonary disease.
    Annals of internal medicine, 1973, Volume: 78, Issue:4

    Topics: Antibodies, Antinuclear; Arrhythmias, Cardiac; Humans; Lung Diseases; Lupus Erythematosus, Systemic;

1973
Medical grand rounds--from the Medical College of Virginia. Drug-induced lupus erythematosus.
    Virginia medical monthly, 1974, Volume: 101, Issue:4

    Topics: Antibodies, Anti-Idiotypic; Antibodies, Antinuclear; Disease Susceptibility; DNA; DNA, Single-Strand

1974
[Etilogy of SLE in connection with induction of antinuclear factors by various drugs].
    Verhandlungen der Deutschen Gesellschaft fur Rheumatologie, 1974, Volume: 3, Issue:0

    Topics: Antibodies, Antinuclear; DNA; DNA Repair; Humans; Isoniazid; Lupus Erythematosus, Systemic; Phenylbu

1974
Studies on drug induced lupus erythematosus in mice. I. Drug induced antinuclear antibodies (ANA).
    Clinical and experimental immunology, 1972, Volume: 11, Issue:2

    Topics: Administration, Oral; Animals; Antibodies, Antinuclear; Antibody Formation; Chlorthalidone; Coombs T

1972
Biologic false-positive FTA-ABS test in drug-induced lupus erythematosus.
    JAMA, 1973, May-14, Volume: 224, Issue:7

    Topics: Arrhythmias, Cardiac; False Positive Reactions; Fluorescent Antibody Technique; Humans; Lupus Erythe

1973
Studies on drug-induced lupus erythematosus in mice. II. Drug-induced smooth muscle and skeletal muscle antibodies.
    Clinical and experimental immunology, 1973, Volume: 15, Issue:3

    Topics: Animals; Antibody Formation; Autoantibodies; Cell Membrane; Chlorthalidone; Fluorescent Antibody Tec

1973
[Drugs as cause of diseases].
    Der Internist, 1974, Volume: 15, Issue:1

    Topics: Abnormalities, Drug-Induced; Berlin; Contraceptives, Oral; Cortisone; Drug-Related Side Effects and

1974
In-vivo nuclear localization of immunoglobulins in clinically normal skin in systemic and procainamide-induced lupus erythematosus.
    The Netherlands journal of medicine, 1974, Volume: 17, Issue:2

    Topics: Adolescent; Adult; Cell Nucleus; Female; Fluorescent Antibody Technique; Humans; Immunoglobulin G; I

1974
Skin immunofluorescence studies on lupus erythematosus and other antinuclear-antibody-positive diseases.
    Annals of internal medicine, 1974, Volume: 80, Issue:4

    Topics: Antibodies, Antinuclear; Arthritis, Rheumatoid; Biopsy; Connective Tissue Diseases; Fluorescent Anti

1974
[Iatrogenic lupus syndromes].
    Les Cahiers de medecine, 1973, Volume: 14, Issue:1

    Topics: Adult; Female; Humans; Isoniazid; Lupus Erythematosus, Systemic; Male; Middle Aged; Procainamide; Sy

1973
[S-thalassemia. Apropos of 40 case reports in Lebanon].
    Le Journal medical libanais. The Lebanese medical journal, 1973, Volume: 26, Issue:5

    Topics: Electrocardiography; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Myocardial Infarction

1973
Drug-induced lupus syndrome presenting as pericardia effusion.
    Le Journal medical libanais. The Lebanese medical journal, 1973, Volume: 26, Issue:5

    Topics: Electrocardiography; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Myocardial Infarction

1973
Drug-induced lupus erythematosus.
    Seminars in hematology, 1973, Volume: 10, Issue:4

    Topics: Antibodies; Cell Membrane; DNA; Drug Hypersensitivity; Humans; Hydralazine; Isoniazid; Lupus Erythem

1973
Procainamide-induced SLE and lymphoreticular disorders.
    Canadian Medical Association journal, 1974, Feb-02, Volume: 110, Issue:3

    Topics: Aortic Diseases; Autopsy; Blindness; Bone Marrow; Digoxin; Drug Therapy, Combination; Heart Diseases

1974
[Medicaments as iatrogenic factors in the onset of lupoid syndromes].
    Medicina interna, 1974, Volume: 26, Issue:1

    Topics: Adolescent; Adult; Anticonvulsants; Humans; Hydralazine; Iatrogenic Disease; Isoniazid; Lupus Erythe

1974
Drug-induced lupus syndrome.
    The Medical letter on drugs and therapeutics, 1974, Apr-12, Volume: 16, Issue:8

    Topics: Acetylation; Anticonvulsants; Female; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic;

1974
[Systemic lupus erythematosus induced by procain amide].
    Archives des maladies du coeur et des vaisseaux, 1968, Volume: 61, Issue:11

    Topics: Arthritis; Female; Fluorescent Antibody Technique; Heart Ventricles; Humans; Lupus Erythematosus, Sy

1968
Immunoglobulin G subclass of human antinuclear antibodies.
    Clinical and experimental immunology, 1970, Volume: 6, Issue:1

    Topics: Antibodies, Antinuclear; Complement Fixation Tests; DNA; Immunodiffusion; Immunoglobulin G; Lupus Er

1970
Procainamide induced systemic lupus erythematosus.
    Military medicine, 1971, Volume: 136, Issue:7

    Topics: Arrhythmias, Cardiac; Female; Humans; Lupus Erythematosus, Systemic; Male; Procainamide

1971
Systemic lupus erythematosus during treatment with procainamide.
    British heart journal, 1972, Volume: 34, Issue:3

    Topics: Adult; Aged; Arrhythmias, Cardiac; Female; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged;

1972
Cardiac tamponade in procainamide induced lupus erythematosus.
    Chest, 1972, Volume: 61, Issue:7

    Topics: Cardiac Tamponade; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Myocardial Infarction;

1972
A morphologic study on the occurrence and distribution of structures resembling viral nucleocapsids in collagen diseases.
    The American journal of medicine, 1972, Volume: 53, Issue:2

    Topics: Arthritis, Rheumatoid; Collagen Diseases; Humans; Inclusion Bodies, Viral; Kidney; Kidney Glomerulus

1972
Procainamide-induced pericardial effusion.
    American heart journal, 1972, Volume: 83, Issue:6

    Topics: Aged; Arrhythmias, Cardiac; Female; Humans; Lupus Erythematosus, Systemic; Pericardial Effusion; Per

1972
Cardiac arrhythmias and the orthopaedic surgeon.
    Clinical orthopaedics and related research, 1972, Volume: 88

    Topics: Acetylcholine; Adult; Aged; Arrhythmias, Cardiac; Carbon Dioxide; Central Nervous System; Chlorides;

1972
Procainamide-induced systemic lupus erythematosus.
    The New Zealand medical journal, 1968, Volume: 68, Issue:437

    Topics: Aged; Female; Humans; Lupus Erythematosus, Systemic; Middle Aged; Procainamide

1968
Procainamide and the systemic lupus erythematosus-like syndrome.
    North Carolina medical journal, 1971, Volume: 32, Issue:2

    Topics: Adult; Aged; Arrhythmias, Cardiac; Female; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged;

1971
Natural antibody to procainamide and procainamide-induced systematic lupus erythematosus.
    Annals of the rheumatic diseases, 1969, Volume: 28, Issue:3

    Topics: Animals; Antibodies, Antinuclear; Arthritis, Rheumatoid; Autoantibodies; Cricetinae; Dogs; Humans; I

1969
[Procainamid induced "LED" with high ANF-titer].
    Lakartidningen, 1970, Aug-19, Volume: 67, Issue:34

    Topics: Adult; Antibodies, Antinuclear; Female; Humans; Lupus Erythematosus, Systemic; Procainamide

1970
[2 cases of systemic lupus erythematosus caused by procaine amide].
    Acta cardiologica, 1970, Volume: 25, Issue:4

    Topics: Aged; Arrhythmias, Cardiac; Female; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Procai

1970
[Lupus erythematosus in the course of treatment with procaine amide: report of a case].
    Kardiologia polska, 1971, Volume: 14, Issue:3

    Topics: Antibodies, Antinuclear; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Procainamide; Tim

1971
[Lupus erythematosus syndrome in the course of procainamide treatment].
    Kardiologia polska, 1971, Volume: 14, Issue:3

    Topics: Antibodies; Antibodies, Antinuclear; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Muscl

1971
[Disseminated lupus erythomatodes in the course of procaine amide treatment].
    Nederlands tijdschrift voor geneeskunde, 1970, Jan-17, Volume: 114, Issue:3

    Topics: Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Procainamide

1970
Drug-induced lupus syndromes.
    British medical journal, 1970, Apr-25, Volume: 2, Issue:5703

    Topics: Anticonvulsants; Drug Hypersensitivity; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemi

1970
Procainamide induced systemic lupus erythematous-like syndrome. Report of one case and review of the literature.
    Le Journal medical libanais. The Lebanese medical journal, 1971, Volume: 24, Issue:1

    Topics: Aged; Humans; Lupus Erythematosus, Systemic; Male; Procainamide

1971
Procainamide-induced L. E. phenomenon.
    Texas medicine, 1968, Volume: 64, Issue:5

    Topics: Aged; Humans; Lupus Erythematosus, Systemic; Male; Procainamide

1968
[Lupus nephropathy. Diagnosis, evolution and treatment].
    Lyon medical, 1968, Sep-15, Volume: 220, Issue:37

    Topics: Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Female; Humans; Kidney Diseases; Lupu

1968
[The lupus erythematosus diseminatus syndrome induced by procaine amide].
    Ugeskrift for laeger, 1968, Dec-05, Volume: 130, Issue:49

    Topics: Blood Sedimentation; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Procainamide; Radiogr

1968
Natural antibodies to procaine amide.
    Clinical and experimental immunology, 1968, Volume: 3, Issue:9

    Topics: Animals; Antibodies; Antibody Formation; Arthritis, Juvenile; Arthritis, Rheumatoid; Cricetinae; Dia

1968
Procainamide induction of a systemic lupus erythematosus-like syndrome. Presentation of six cases, review of the literature, and analysis and followup of reported cases.
    Medicine, 1969, Volume: 48, Issue:3

    Topics: Adult; Aged; Child, Preschool; Female; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Pro

1969
Pulmonary sequelae in procaine amide induced lupus-like syndrome.
    Diseases of the chest, 1969, Volume: 55, Issue:2

    Topics: Adult; Diagnosis, Differential; Drug Hypersensitivity; Humans; Lung Diseases; Lupus Erythematosus, S

1969
Drug-induced systemic lupus erythematosus.
    JAMA, 1969, Apr-21, Volume: 208, Issue:3

    Topics: Humans; Hydralazine; Lupus Erythematosus, Systemic; Procainamide

1969
Myotonia, procaine amide, and lupus-like syndrome.
    Archives of neurology, 1966, Volume: 14, Issue:3

    Topics: Adult; Aged; Female; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Myotonic Dystrophy; P

1966
Ventricular tachycardia: treatment with very large doses of procaine amide.
    The Medical clinics of North America, 1966, Volume: 50, Issue:1

    Topics: Arthritis; Electrocardiography; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Procainami

1966