procainamide has been researched along with Lupus Erythematosus, Systemic in 286 studies
Procainamide: A class Ia antiarrhythmic drug that is structurally-related to PROCAINE.
procainamide : A benzamide that is 4-aminobenzamide substituted on the amide N by a 2-(diethylamino)ethyl group. It is a pharmaceutical antiarrhythmic agent used for the medical treatment of cardiac arrhythmias.
Lupus Erythematosus, Systemic: A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Procainamide (PA) has been a mainstay of treatment against acute and chronic supraventricular and ventricular arrhythmias for more than 30 years." | 8.76 | Procainamide: clinical pharmacology and efficacy against ventricular arrhythmias. ( Giardina, EG, 1984) |
| "A 61-year-old man developed clinical lupus syndrome with positive antinuclear antibody, positive lupus erythematosus (LE) cell preparation, and diffuse proliferative glomerulonephritis following 26 months of procainamide therapy." | 8.76 | Glomerulonephritis in procainamide induced lupus erythematosus: report of a case and review of the literature. ( Erickson, DG; Foucar, E; Tung, KS, 1979) |
| "Procainamide hydrochloride-induced thrombocytopenia has infrequently been reported in the past." | 7.67 | Thrombocytopenia following sustained-release procainamide. ( Carlson, RJ; Gottlieb, AJ; Meisner, DJ, 1985) |
| "We report a case of the nephrotic syndrome occurring in a patient with procainamide induced LE." | 7.66 | Nephrotic syndrome in procainamide induced lupus nephritis. ( Bernheim, J; Blanc-Brunat, N; Colon, S; Labeeuw, M; Zech, P, 1979) |
| "A rare case of constrictive pericarditis in procainamide-induced lupus erythematosus syndrome is reported." | 7.65 | Constrictive pericarditis in procainamide-induced lupus erythematosus syndrome. ( Shah, A; Sunder, SK, 1975) |
| "A 63-year-old man developed an asymptomatic pleural effusion following the administration of 500 gm of procainamide hydrochloride over a six-month period." | 7.65 | Lupus erythematosus cells in pleural effusion: the initial manifestation of procainamide-induced lupus erythematosus. ( Carel, RS; Gutman, A; Shapiro, MS; Shoham, D, 1977) |
| "Prednisolone was administered." | 5.30 | [Procainamide-induced lupus in a patient with bilateral pleural effusion]. ( Hisauchi, K; Mitunaga, K; Miyake, S; Ohtani, Y; Sawada, M; Sumi, Y; Yamashita, Y; Yoshizawa, Y, 1998) |
| "Pericarditis has been reported to occur in from 14 to 18 per cent of the cases of procainamide-induced lupus erythematosus, and occasional reports of massive pericardial effusion, pericardial tamponade and constrictive pericarditis have appeared in the literature." | 5.26 | Procainamide-induced lupus erythematosus pericarditis encountered during coronary bypass sugery. ( Goldberg, MJ; Husain, M; Rubenfire, M; Wajszczuk, WJ, 1980) |
| "Procainamide (PA) has been a mainstay of treatment against acute and chronic supraventricular and ventricular arrhythmias for more than 30 years." | 4.76 | Procainamide: clinical pharmacology and efficacy against ventricular arrhythmias. ( Giardina, EG, 1984) |
| "A 61-year-old man developed clinical lupus syndrome with positive antinuclear antibody, positive lupus erythematosus (LE) cell preparation, and diffuse proliferative glomerulonephritis following 26 months of procainamide therapy." | 4.76 | Glomerulonephritis in procainamide induced lupus erythematosus: report of a case and review of the literature. ( Erickson, DG; Foucar, E; Tung, KS, 1979) |
| "Procainamide hydrochloride-induced thrombocytopenia has infrequently been reported in the past." | 3.67 | Thrombocytopenia following sustained-release procainamide. ( Carlson, RJ; Gottlieb, AJ; Meisner, DJ, 1985) |
| "An 82-year-old woman developed symptomatic reactive hypoglycemia in the same year she developed a lupus-like syndrome, probably secondary to the administration of procainamide or hydralazine." | 3.66 | Reactive hypoglycemia and insulin autoantibodies in drug-induced lupus erythematosus. ( Blackshear, PJ; Kahn, CR; Kriauciunas, KA; Rotner, HE, 1983) |
| "We report a case of the nephrotic syndrome occurring in a patient with procainamide induced LE." | 3.66 | Nephrotic syndrome in procainamide induced lupus nephritis. ( Bernheim, J; Blanc-Brunat, N; Colon, S; Labeeuw, M; Zech, P, 1979) |
| "Renal failure secondary to crescentic glomerulonephritis developed in a patient who had typical serologic features of drug-induced systemic lupus erythematosus after two years of therapy with procainamide." | 3.66 | Renal manifestations of drug-induced systemic lupus erythematosus. ( Charron, RC; Katz, A; Sheikh, TK, 1981) |
| "A rare case of constrictive pericarditis in procainamide-induced lupus erythematosus syndrome is reported." | 3.65 | Constrictive pericarditis in procainamide-induced lupus erythematosus syndrome. ( Shah, A; Sunder, SK, 1975) |
| "A 63-year-old man developed an asymptomatic pleural effusion following the administration of 500 gm of procainamide hydrochloride over a six-month period." | 3.65 | Lupus erythematosus cells in pleural effusion: the initial manifestation of procainamide-induced lupus erythematosus. ( Carel, RS; Gutman, A; Shapiro, MS; Shoham, D, 1977) |
| "Further study of drug-induced systemic lupus erythematosus is necessary in order to resolve these problems regarding pathogenesis." | 2.36 | Drug-induced systemic lupus erythematosus. ( Weinstein, A, 1980) |
| "Extensive serologic changes occur in systemic lupus erythematosus (SLE) which are probably secondary to unknow primary cause(s)." | 2.35 | Serologic abnormalities in spontaneous and drug-induced systemic lupus erythematosus. ( Dubois, EL, 1975) |
| "We analysed all ICSRs classified as 'systemic lupus erythematosus' according to the Medical Dictionary for Drug Regulatory Activities term (preferred term level) in VigiBase." | 1.51 | Drug-induced systemic lupus: revisiting the ever-changing spectrum of the disease using the WHO pharmacovigilance database. ( Arnaud, L; Chasset, F; Gavand, PE; Lambert, A; Lebrun-Vignes, B; Martin, T; Mertz, P; Muller, C; Salem, JE; Sibilia, J; Tebacher-Alt, M, 2019) |
| "Procainamide is a competitive DNA methyltransferase (Dnmt) inhibitor, hydralazine inhibits ERK pathway signaling thereby decreasing Dnmt expression, and in lupus T cells decreased ERK pathway signaling causing a similar Dnmt decrease." | 1.33 | Demethylation of the same promoter sequence increases CD70 expression in lupus T cells and T cells treated with lupus-inducing drugs. ( Lu, Q; Richardson, BC; Wu, A, 2005) |
| "Necrosis was induced by heating." | 1.33 | Quinidine and procainamide inhibit murine macrophage uptake of apoptotic and necrotic cells: a novel contributing mechanism of drug-induced-lupus. ( Ablin, J; Metzger, S; Mevorach, D; Trahtemberg, U; Verbovetski, I, 2005) |
| "Procainamide (PA) may cause drug-induced lupus, and its reactive metabolites, hydroxylamine-PA (HAPA) and nitroso-PA, are held responsible for this." | 1.30 | Procainamide, a drug causing lupus, induces prostaglandin H synthase-2 and formation of T cell-sensitizing drug metabolites in mouse macrophages. ( Abel, J; Degen, G; Gleichmann, E; Goebel, C; Mittmann, S; Sachs, B; Schraa, S; Uetrecht, J; Vogel, C; Wulferink, M, 1999) |
| "Prednisolone was administered." | 1.30 | [Procainamide-induced lupus in a patient with bilateral pleural effusion]. ( Hisauchi, K; Mitunaga, K; Miyake, S; Ohtani, Y; Sawada, M; Sumi, Y; Yamashita, Y; Yoshizawa, Y, 1998) |
| " Long term administration of this compound may induce a variety of immunological abnormalities, including antinuclear antibodies." | 1.28 | Pulmonary thromboembolism associated with procainamide induced lupus syndrome and anticardiolipin antibodies. ( Asherson, RA; Hughes, GR; Zulman, J, 1989) |
| "Though there are analogies to the systemic lupus erythematosus, we must take into consideration a diversity of diseases." | 1.27 | [Drug-induced lupus erythematosus syndrome. Pathogenesis and relation to systemic lupus erythematosus]. ( Wollina, U, 1984) |
| "Procainamide has a high propensity for the induction of an autoimmune response." | 1.27 | Autoallergic reactions induced by procainamide. ( Rubin, RL; Tan, EM, 1984) |
| "The sera of patients with systemic lupus erythematosus (SLE) and drug-induced lupus (DIL) were used to study the antigenic regions of histone 1 (H1) that bind antibodies in these sera." | 1.27 | Antibodies in procainamide-induced and systemic lupus erythematosus bind the C-terminus of histone 1 (H1). ( Fritzler, MJ; Gohill, J, 1987) |
| "Procainamide-induced lupus is a well-recognized syndrome, but the events leading up to clinical symptoms are obscure." | 1.27 | Serologic changes during induction of lupus-like disease by procainamide. ( Curd, JG; Johnson, AD; Nusinow, SR; Rubenson, DS; Rubin, RL; Tan, EM, 1986) |
| "Five drugs associated with systemic lupus erythematosus were studied for their effect on the salt-induced right-handed (B) to left-handed (Z) transition of poly(dG-me5dC) X poly(dG-me5dC)." | 1.27 | Effects of lupus-inducing drugs on the B to Z transition of synthetic DNA. ( Messner, RP; Thomas, TJ, 1986) |
| "Hydralazine was shown to interact with a soluble DNA-histone complex, and the resulting interaction rendered the histone moiety resistant to trypsin digestion." | 1.26 | The role of histones as nuclear autoantigens in drug-related lupus erythematosus. ( Portanova, JP; Tan, EM, 1981) |
| "Procainamide has become the most frequent cause of the drug-induced lupus syndrome." | 1.26 | SLE: idiopathic or drug-induced? ( Condemi, JJ, 1980) |
| "The procainamide group was compared with patients with spontaneous systemic lupus erythematosus (n = 15) and a normal control population (n = 40)." | 1.26 | Immune regulatory abnormalities produced by procainamide. ( Miller, KB; Salem, D, 1982) |
| "Approximately 8% of patients with systemic lupus erythematosus have drug induced disease." | 1.26 | [New aspects of drug induced lupus erythematosus (author's transl)]. ( Robinson, HM, 1978) |
| "Procainamide-induced systemic lupus erythematosus (SLE) is a well recognized clinical syndrome believed to be characterized by normocomplementemia." | 1.26 | Procainamide-induced systemic lupus erythematosus with hypocomplementemia. ( Diaz, R; Quigley, TJ; Rao, KV, 1977) |
| "These data suggest that systemic lupus erythematosus and procainamide-induced lupus may differ in the relative reversibility of a regulatory defect associated with a Con A responsive population of peripheral blood mononuclear (PBM) cells." | 1.26 | Inhibition of Con A mitogenesis by serum from procainamide-treated patients and patients with systemic lupus erythematosus. ( Cunningham-Rundles, S; Tannen, RH, 1982) |
| "To assess the efficacy, plasma drug concentrations and adverse effects of a new sustained release preparation of procainamide, 33 patients with heart disease were studied in an acute dose-ranging protocol and a chronic treatment protocol." | 1.26 | Efficacy, plasma concentrations and adverse effects of a new sustained release procainamide preparation. ( Bigger, JT; Fenster, PE; Giardina, EG; Marcus, FI; Mayersohn, M; Perrier, D, 1980) |
| "Pericarditis has been reported to occur in from 14 to 18 per cent of the cases of procainamide-induced lupus erythematosus, and occasional reports of massive pericardial effusion, pericardial tamponade and constrictive pericarditis have appeared in the literature." | 1.26 | Procainamide-induced lupus erythematosus pericarditis encountered during coronary bypass sugery. ( Goldberg, MJ; Husain, M; Rubenfire, M; Wajszczuk, WJ, 1980) |
| "Treatment with prednisone produced impressive amelioration of the pericarditis with no recurrence of the lupus erythematosis syndrome during a prolonged period of observation following cessation of corticosteroid therapy." | 1.25 | Pericardial tamponade. A presenting manifestation of procainamide-induced lupus erythematosus. ( Ghose, MK, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 235 (82.17) | 18.7374 |
| 1990's | 31 (10.84) | 18.2507 |
| 2000's | 15 (5.24) | 29.6817 |
| 2010's | 4 (1.40) | 24.3611 |
| 2020's | 1 (0.35) | 2.80 |
| Authors | Studies |
|---|---|
| He, Y | 1 |
| Sawalha, AH | 1 |
| Arnaud, L | 1 |
| Mertz, P | 1 |
| Gavand, PE | 1 |
| Martin, T | 1 |
| Chasset, F | 1 |
| Tebacher-Alt, M | 1 |
| Lambert, A | 1 |
| Muller, C | 1 |
| Sibilia, J | 1 |
| Lebrun-Vignes, B | 1 |
| Salem, JE | 1 |
| Pan, Q | 1 |
| Guo, Y | 1 |
| Guo, L | 1 |
| Liao, S | 1 |
| Zhao, C | 1 |
| Wang, S | 1 |
| Liu, HF | 1 |
| Vedove, CD | 1 |
| Del Giglio, M | 1 |
| Schena, D | 1 |
| Girolomoni, G | 1 |
| Marzano, AV | 1 |
| Vezzoli, P | 1 |
| Crosti, C | 1 |
| Katz, U | 1 |
| Zandman-Goddard, G | 1 |
| Wong-Baeza, C | 1 |
| Hernández-Pando, R | 1 |
| Reséndiz, A | 1 |
| Tescucano, A | 1 |
| Bustos, I | 1 |
| Ibáñez, M | 1 |
| Wong, C | 1 |
| Baeza, I | 1 |
| Lu, Q | 5 |
| Kaplan, M | 1 |
| Ray, D | 2 |
| Zacharek, S | 1 |
| Gutsch, D | 1 |
| Richardson, B | 6 |
| Deng, C | 2 |
| Zhang, Z | 1 |
| Rao, T | 1 |
| Attwood, J | 1 |
| Yung, R | 2 |
| LADD, AT | 1 |
| HAHN, AL | 1 |
| KAPLAN, JM | 1 |
| WACHTEL, HL | 1 |
| CZARNECKI, SW | 1 |
| SAMPSON, JJ | 1 |
| KINGERY, FA | 1 |
| COLMAN, RW | 1 |
| STURGILL, BC | 1 |
| Oelke, K | 1 |
| Richardson, D | 1 |
| Wu, A | 2 |
| Hanash, S | 1 |
| Richardson, BC | 4 |
| Suwa, A | 1 |
| Ablin, J | 1 |
| Verbovetski, I | 1 |
| Trahtemberg, U | 1 |
| Metzger, S | 1 |
| Mevorach, D | 1 |
| Ohnishi, A | 1 |
| Nonaka, Y | 1 |
| Takei, S | 1 |
| Zhou, Y | 1 |
| Skipworth, GB | 1 |
| Morris, JB | 1 |
| Goldstein, N | 1 |
| Rosin, JM | 1 |
| Hanlon, TM | 1 |
| Binkiewicz, A | 1 |
| Feingold, M | 1 |
| Necheles, TF | 1 |
| McDevitt, DG | 1 |
| Glascow, JF | 1 |
| Compton-Smith, RN | 1 |
| Fawcett, JW | 1 |
| Siegel, M | 1 |
| Lee, SL | 2 |
| Peress, NS | 1 |
| Giardina, EG | 2 |
| Russell, PJ | 1 |
| Doolan, TJ | 1 |
| Webb, J | 1 |
| Carr, GA | 1 |
| DeSwarte, RD | 1 |
| Ahmad, S | 1 |
| Goldberg, MJ | 1 |
| Husain, M | 1 |
| Wajszczuk, WJ | 1 |
| Rubenfire, M | 1 |
| Fenster, PE | 2 |
| Bigger, JT | 1 |
| Mayersohn, M | 1 |
| Perrier, D | 1 |
| Marcus, FI | 1 |
| González, ER | 1 |
| Reidenberg, MM | 6 |
| Bluestein, HG | 3 |
| Redelman, D | 1 |
| Zvaifler, NJ | 3 |
| Uetrecht, JP | 1 |
| Freeman, RW | 1 |
| Woosley, RL | 2 |
| Edwards, RL | 1 |
| Rick, ME | 1 |
| Wakem, CJ | 1 |
| Tannen, RH | 3 |
| Cunningham-Rundles, S | 1 |
| Miller, KB | 1 |
| Salem, D | 1 |
| Jacobs, RP | 1 |
| Blackshear, PJ | 1 |
| Rotner, HE | 1 |
| Kriauciunas, KA | 1 |
| Kahn, CR | 1 |
| Tan, EM | 10 |
| Rubin, RL | 13 |
| Klajman, A | 4 |
| Kafri, B | 1 |
| Shohat, T | 1 |
| Drucker, I | 1 |
| Moalem, T | 1 |
| Jaretzky, A | 1 |
| Goldberg, SK | 1 |
| Lipschutz, JB | 1 |
| Ricketts, RM | 1 |
| Fein, AM | 1 |
| Browning, CA | 1 |
| Bishop, RL | 1 |
| Heilpern, RJ | 1 |
| Singh, JB | 1 |
| Spodick, DH | 1 |
| Wollina, U | 1 |
| Sanfelippo, MJ | 1 |
| Drayna, CJ | 1 |
| Harmon, CE | 1 |
| Portanova, JP | 3 |
| Schifman, RB | 1 |
| Garewal, H | 1 |
| Shillington, D | 1 |
| van Pham, C | 1 |
| Noguchi, J | 1 |
| Quismorio, FP | 1 |
| Haywood, LJ | 1 |
| Condemi, JJ | 4 |
| Greenspan, AM | 1 |
| Horowitz, LN | 1 |
| Spielman, SR | 1 |
| Josephson, ME | 1 |
| Seligmann, H | 1 |
| Potasman, I | 1 |
| Bassan, H | 1 |
| Weber, WW | 2 |
| Wanner, WR | 1 |
| Irvin, WS | 1 |
| Holborow, EJ | 1 |
| Weinstein, A | 1 |
| Chubick, A | 1 |
| Sheikh, TK | 1 |
| Charron, RC | 1 |
| Katz, A | 1 |
| Schoen, RT | 1 |
| Trentham, DE | 1 |
| Cohen, MN | 1 |
| Hess, EV | 4 |
| Chokron, R | 1 |
| Robert, A | 1 |
| Rozensztajn, L | 1 |
| Abuaf, N | 1 |
| Dumoulin, P | 1 |
| Valty, J | 1 |
| Gupta, AK | 1 |
| Porwal, P | 1 |
| Nuwal, NK | 1 |
| Gagrani, MR | 1 |
| Porwal, K | 1 |
| Healey, LA | 2 |
| Parker, CW | 1 |
| Fontiveros, ES | 1 |
| Cumming, WJ | 1 |
| Hudgson, P | 1 |
| Yung, RL | 3 |
| Quddus, J | 2 |
| Chrisp, CE | 2 |
| Johnson, KJ | 2 |
| Alloway, JA | 1 |
| Salata, MP | 1 |
| Pauls, JD | 3 |
| Edworthy, SM | 1 |
| Fritzler, MJ | 5 |
| Gavalchin, J | 1 |
| Amento, EP | 1 |
| Uetrecht, J | 3 |
| Burlingame, RW | 1 |
| Arnott, JE | 1 |
| Totoritis, MC | 3 |
| McNally, EM | 3 |
| Johnson, AD | 2 |
| Jiang, X | 1 |
| Khursigara, G | 1 |
| Cohen, MG | 1 |
| Adams, LE | 2 |
| Roberts, SM | 2 |
| Donovan-Brand, R | 2 |
| Zimmer, H | 1 |
| McDonald, E | 1 |
| Marino, C | 1 |
| Muramatsu, M | 1 |
| Nakajima, M | 1 |
| Mori, M | 1 |
| Sobashima, H | 1 |
| Sano, H | 1 |
| Katao, K | 1 |
| Miyasaka, N | 1 |
| Kretz-Rommel, A | 2 |
| Duncan, SR | 1 |
| Williams, R | 1 |
| Johnson, K | 1 |
| Phillips, C | 1 |
| Stoolman, L | 1 |
| Chang, S | 1 |
| Ohtani, Y | 1 |
| Sumi, Y | 1 |
| Hisauchi, K | 1 |
| Sawada, M | 1 |
| Miyake, S | 1 |
| Yamashita, Y | 1 |
| Mitunaga, K | 1 |
| Yoshizawa, Y | 1 |
| McLaughlin, K | 1 |
| Gholoum, B | 1 |
| Guiraudon, C | 1 |
| Jevnikar, A | 1 |
| Muirhead, N | 1 |
| Kameda, H | 1 |
| Mimori, T | 1 |
| Kaburaki, J | 1 |
| Fujii, T | 1 |
| Takahashi, T | 1 |
| Akaishi, M | 1 |
| Ikeda, Y | 1 |
| Lau, CC | 1 |
| Clos, TD | 1 |
| Goebel, C | 1 |
| Vogel, C | 1 |
| Wulferink, M | 1 |
| Mittmann, S | 1 |
| Sachs, B | 1 |
| Schraa, S | 1 |
| Abel, J | 1 |
| Degen, G | 1 |
| Gleichmann, E | 1 |
| Amano, K | 1 |
| Takeuchi, T | 1 |
| Mongey, AB | 1 |
| Hess, E | 2 |
| Salomon, DR | 1 |
| Guerrero, RS | 1 |
| Drayer, DE | 4 |
| Jones, WN | 1 |
| Trinca, CE | 1 |
| Walson, PD | 1 |
| Weiller, PJ | 2 |
| Lammy, S | 1 |
| Weiller, M | 1 |
| Gabriel, B | 1 |
| Sayag, J | 1 |
| Mongin, M | 2 |
| Novack, MA | 1 |
| Paine, R | 2 |
| Dubois, EL | 4 |
| CHase, PH | 1 |
| Henningsen, NC | 1 |
| Cederberg, A | 1 |
| Hanson, A | 1 |
| Johansson, BW | 1 |
| Warner, WA | 1 |
| Carel, RS | 2 |
| Shapiro, MS | 2 |
| Shoham, D | 1 |
| Gutman, A | 2 |
| Kaplan, AI | 1 |
| Zakher, F | 1 |
| Sabin, S | 1 |
| Cordoba, O | 1 |
| Taragan, R | 1 |
| Weisman, MH | 1 |
| Shapiro, RF | 1 |
| Bernstein, RE | 1 |
| Lahita, R | 1 |
| Kluger, J | 1 |
| Koffler, D | 1 |
| Sonnhag, C | 1 |
| Karlsson, E | 1 |
| Hed, J | 1 |
| Foucar, E | 1 |
| Erickson, DG | 1 |
| Tung, KS | 1 |
| Geltman, EM | 1 |
| Gelfand, ML | 1 |
| Kahn, MF | 3 |
| Manicacci, M | 1 |
| Segresta, JM | 1 |
| Caulin, C | 1 |
| Montagne, A | 2 |
| Weiss, RB | 1 |
| Simpson, PB | 1 |
| Oppenheim, RC | 1 |
| Oka, M | 1 |
| Räsänen, J | 1 |
| Häkkinen, P | 1 |
| Pinnas, JL | 1 |
| Dandavino, R | 1 |
| Bach, JF | 1 |
| Nies, AS | 1 |
| Carr, K | 1 |
| Oates, JA | 1 |
| Stec, GP | 1 |
| Lertora, JJ | 1 |
| Atkinson, AJ | 1 |
| Nevin, MJ | 1 |
| Kushner, W | 1 |
| Jones, C | 1 |
| Schmid, FR | 1 |
| Askenazi, J | 1 |
| Homma, M | 1 |
| Michalevicz, R | 1 |
| Many, A | 1 |
| Ramot, B | 1 |
| McLain, DA | 1 |
| Hahn, BH | 1 |
| Hoff, BH | 1 |
| Zech, P | 2 |
| Colon, S | 1 |
| Labeeuw, M | 1 |
| Bernheim, J | 1 |
| Blanc-Brunat, N | 1 |
| Schwarz, JA | 1 |
| Sahenk, Z | 1 |
| Mendell, JR | 1 |
| Rossio, JL | 1 |
| Hurtubise, P | 1 |
| Goldman, P | 1 |
| Ingelfinger, JA | 1 |
| Robinson, HM | 1 |
| Nick, J | 1 |
| Combrisson, A | 1 |
| Reignier, A | 1 |
| Verdy, E | 1 |
| Gally, AM | 1 |
| Bakouche, P | 1 |
| Dudognon, P | 1 |
| Dray, C | 1 |
| Davis, S | 1 |
| Furie, BC | 1 |
| Griffin, JH | 1 |
| Furie, B | 1 |
| Willey, R | 1 |
| Wierzchowiecki, M | 1 |
| Rybicka, K | 1 |
| Whittle, TS | 1 |
| Ainsworth, SK | 1 |
| Rao, KV | 1 |
| Diaz, R | 1 |
| Quigley, TJ | 1 |
| Schubothe, H | 1 |
| Maas, D | 1 |
| Bell, WR | 1 |
| Boss, GR | 1 |
| Wolfson, JS | 1 |
| Levo, Y | 1 |
| Pick, AI | 1 |
| Avidor, I | 1 |
| Ben-Bassat, M | 1 |
| Cohmen, G | 1 |
| Ghose, MK | 1 |
| Sunder, SK | 1 |
| Shah, A | 1 |
| Falko, JM | 1 |
| Thomas, FB | 1 |
| Utsinger, PD | 1 |
| Stevens, MB | 2 |
| Zacharias, W | 1 |
| Koopman, WJ | 1 |
| Gohill, J | 3 |
| Smith, PR | 1 |
| Nacht, RI | 1 |
| Sim, E | 2 |
| Sheikh, S | 1 |
| Seggev, JS | 1 |
| Abu-Shakra, M | 1 |
| Shoenfeld, Y | 2 |
| Arndt, RE | 1 |
| Kotzin, BL | 1 |
| Craft, JE | 1 |
| Radding, JA | 1 |
| Harding, MW | 1 |
| Bernstein, RM | 1 |
| Hardin, JA | 1 |
| Clyne, LP | 1 |
| Farber, LR | 1 |
| Chopyk, RL | 1 |
| Asherson, RA | 1 |
| Zulman, J | 1 |
| Hughes, GR | 1 |
| Sanders, CE | 1 |
| Budinsky, RA | 1 |
| Meisner, DJ | 1 |
| Carlson, RJ | 1 |
| Gottlieb, AJ | 1 |
| Vivino, FB | 1 |
| Schumacher, HR | 1 |
| Mohindra, SK | 1 |
| Udeani, GO | 1 |
| Abrahamson, D | 1 |
| Ninos, NP | 1 |
| Tomura, T | 1 |
| van Lancker, JL | 1 |
| Lovisetto, P | 1 |
| Mairano, D | 1 |
| Cargnino, M | 1 |
| Biarese, V | 1 |
| Marchi, L | 1 |
| Lerda, R | 1 |
| Agudelo, CA | 1 |
| Wise, CM | 1 |
| Lyles, MF | 1 |
| Forrester, J | 1 |
| Golbus, J | 1 |
| Brede, D | 1 |
| Hudson, J | 1 |
| Chan, EK | 2 |
| Sullivan, KF | 1 |
| Kucharz, EJ | 1 |
| Nishikai, M | 1 |
| Sugimoto, M | 1 |
| Sato, A | 1 |
| Honda, M | 1 |
| Naito, M | 1 |
| Nagoshi, H | 1 |
| Weisbart, RH | 1 |
| Yee, WS | 1 |
| Colburn, KK | 1 |
| Whang, SH | 1 |
| Heng, MK | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Monitoring the IMmUological TOXicity of Drugs[NCT03480529] | 662 participants (Actual) | Observational [Patient Registry] | 2018-03-01 | Completed | |||
| Fasting Hypoglycemia: Diagnosis and Treatment[NCT00001276] | 1,500 participants (Anticipated) | Observational | 1991-05-21 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
45 reviews available for procainamide and Lupus Erythematosus, Systemic
| Article | Year |
|---|---|
Drug-induced lupus erythematosus: an update on drugs and mechanisms.
Topics: Autoimmunity; Genetic Predisposition to Disease; Humans; Hydralazine; Immunologic Factors; Lupus Ery | 2018 |
Mechanistic Insights of Chemicals and Drugs as Risk Factors for Systemic Lupus Erythematosus.
Topics: Autoimmune Diseases; Female; Humans; Hydralazine; Lupus Erythematosus, Systemic; Procainamide; Risk | 2020 |
Drug-induced lupus erythematosus.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Arrhythmia Agents; Antibodies; Antifungal Ag | 2009 |
Drug-induced lupus: an update on its dermatologic aspects.
Topics: Anti-Arrhythmia Agents; Anti-Bacterial Agents; Antihypertensive Agents; Antitubercular Agents; Autoa | 2009 |
Drug-induced lupus: an update.
Topics: Anti-Arrhythmia Agents; Humans; Hydralazine; Lupus Erythematosus, Systemic; Procainamide; Tumor Necr | 2010 |
DNA methylation and autoimmune disease.
Topics: Animals; Autoimmune Diseases; Autoimmunity; Azacitidine; Cell Communication; DNA Methylation; Humans | 2003 |
[Immunologic tests: Anti-histone antibodies].
Topics: Antibodies, Antinuclear; Biomarkers; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Techniq | 2005 |
[Drug-induced pericarditis].
Topics: Adrenal Cortex Hormones; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Antineopla | 2007 |
[Drug-induced lupus erythematosus].
Topics: Anti-Arrhythmia Agents; Antihypertensive Agents; Drug-Related Side Effects and Adverse Reactions; Hu | 2007 |
DNA methylation in T cells from idiopathic lupus and drug-induced lupus patients.
Topics: Autoantibodies; B-Lymphocytes; CD4-Positive T-Lymphocytes; Cytokines; Cytotoxicity, Immunologic; DNA | 2008 |
Procainamide: clinical pharmacology and efficacy against ventricular arrhythmias.
Topics: Acecainide; Administration, Oral; Animals; Arrhythmias, Cardiac; Electrocardiography; Heart; Humans; | 1984 |
Drug-induced lupus: clinical and serological studies.
Topics: Acetyltransferases; Adult; Antibodies, Antinuclear; Anticonvulsants; Arthritis; Chlorpromazine; Cros | 1982 |
Drug-induced systemic lupus erythematosus.
Topics: Antibodies, Antinuclear; Anticonvulsants; Chlorpromazine; Humans; Hydralazine; Isoniazid; Lupus Eryt | 1980 |
DNA antibodies in systemic lupus erythematosus and pseudolupus syndrome.
Topics: Animals; Antibodies; Antibody Specificity; Antigen-Antibody Complex; Counterimmunoelectrophoresis; C | 1980 |
Drug-induced lupus: an adjuvant disease?
Topics: Adjuvants, Immunologic; Animals; Autoimmune Diseases; Humans; Hydralazine; Lupus Erythematosus, Syst | 1981 |
Role of T cell DNA methylation in lupus syndromes.
Topics: Azacitidine; DNA; Humans; Lupus Erythematosus, Systemic; Lymphocyte Function-Associated Antigen-1; M | 1994 |
Quinidine-induced rheumatic syndromes.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Antinuclear; Atrial Fibrillation; Child; Diagnosis, Diff | 1995 |
Procainamide-induced lupus in the elderly.
Topics: Aged; Antibodies, Antinuclear; Diagnosis, Differential; Female; Humans; Lupus Erythematosus, Systemi | 1993 |
Drug-induced lupus.
Topics: Antibodies, Antinuclear; Anticonvulsants; Ethosuximide; Female; Humans; Hydralazine; Lupus Erythemat | 1996 |
[Drug-induced lupus erythematosus].
Topics: Autoimmunity; Diagnosis, Differential; Drug-Related Side Effects and Adverse Reactions; Humans; Hydr | 2000 |
Serologic abnormalities in spontaneous and drug-induced systemic lupus erythematosus.
Topics: Animals; Anti-Bacterial Agents; Antibodies, Anti-Idiotypic; Antibodies, Antinuclear; Anticonvulsants | 1975 |
Drug-induced systemic lupus erythematosus: a critical review.
Topics: Adult; Allopurinol; Anti-Arrhythmia Agents; Anticonvulsants; Antithyroid Agents; Antitubercular Agen | 1975 |
Glomerulonephritis in procainamide induced lupus erythematosus: report of a case and review of the literature.
Topics: Azathioprine; Biopsy; Glomerulonephritis; Humans; Kidney Glomerulus; Lupus Erythematosus, Systemic; | 1979 |
[Antinuclear antibodies in connective tissue diseases (author's transl)].
Topics: Adolescent; Adult; Aged; Animals; Antibodies, Antinuclear; Antigen-Antibody Complex; Autoantigens; C | 1978 |
Drug-induced immune complex disease.
Topics: Amino Acid Sequence; Antigen-Antibody Complex; Complement Activation; Complement C4; Humans; Hydrala | 1991 |
Metabolism of drugs by activated leukocytes: implications for drug-induced lupus and other drug hypersensitivity reactions.
Topics: Antibody Formation; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions; Humans; | 1991 |
Human anti-DNA idiotype (16/6 idiotype): pathogenic role in autoimmunity.
Topics: Animals; Antibodies, Anti-Idiotypic; Antibodies, Antinuclear; Antibodies, Monoclonal; Autoantibodies | 1990 |
Drug-induced immune-complex disease.
Topics: Humans; Hydralazine; Immune Complex Diseases; Isoniazid; Lupus Erythematosus, Systemic; Penicillamin | 1989 |
[Drug-induced lupus].
Topics: Acetylation; Adrenergic beta-Antagonists; Antibodies, Antinuclear; Anticonvulsants; B-Lymphocytes; D | 1985 |
Pure red cell aplasia in procainamide induced systemic lupus erythematosus. Report and review of the literature.
Topics: Aged; Humans; Lupus Erythematosus, Systemic; Male; Procainamide; Red-Cell Aplasia, Pure | 1988 |
Antinuclear antibodies (ANAs): diagnostically specific immune markers and clues toward the understanding of systemic autoimmunity.
Topics: Antibodies, Antinuclear; Autoantigens; Autoimmune Diseases; Cell Nucleus; Connective Tissue Diseases | 1988 |
[Pathogenesis of drug-induced collagenosis-like syndrome].
Topics: Humans; Hydralazine; Lupus Erythematosus, Systemic; Procainamide | 1987 |
Connective tissue disease in the elderly.
Topics: Aged; Connective Tissue Diseases; Dermatomyositis; Female; Giant Cell Arteritis; Humans; Hydralazine | 1986 |
Drug-induced systemic lupus erythematosus. Differentiating it from the real thing.
Topics: Diagnosis, Differential; Female; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Male | 1985 |
Drug-induced lupus: clinical spectrum and pathogenesis.
Topics: Acetylation; Adult; Aged; Antibodies, Antinuclear; Antibody Specificity; Autoimmune Diseases; Black | 1985 |
[Side effects of anti-arrhythmic agents].
Topics: 1-Propanol; Adrenal Cortex Hormones; Agranulocytosis; Anorexia Nervosa; Anti-Arrhythmia Agents; Anti | 1971 |
Systemic lupus erythematosus.
Topics: Antibodies, Antinuclear; Arthritis, Rheumatoid; Female; Hepatitis; Humans; Hydralazine; Immunoglobul | 1973 |
[Iatrogenic lupus: present status of the problem. II. Physiopathology of induced lupus].
Topics: Animals; Antibodies, Antinuclear; Disease Models, Animal; DNA, Viral; Drug-Related Side Effects and | 1972 |
Antinuclear antibodies.
Topics: Animals; Antibodies, Antinuclear; Antibody Formation; Arthritis, Rheumatoid; Autoantigens; Cytotoxic | 1972 |
Lupus-like syndromes induced by drugs.
Topics: Antibodies, Antinuclear; Antibody Formation; Arthritis, Rheumatoid; Chlorpromazine; DNA, Single-Stra | 1974 |
[Generalized lupus erythematosus caused by methyl-phenyl-ethyl-hydantoin].
Topics: Adult; Autoimmune Diseases; Female; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; M | 1967 |
Lupus erythematosus.
Topics: Antibodies, Antinuclear; Contraceptives, Oral; DNA; Female; Fluorescent Antibody Technique; Humans; | 1972 |
A primer of collagen disease.
Topics: Administration, Topical; Adult; Anti-Inflammatory Agents; Antibodies; Central Nervous System Disease | 1974 |
Drug-induced lupus syndromes.
Topics: Antibodies, Antinuclear; Anticonvulsants; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Syste | 1969 |
Procaine amide-induced systemic lupus erythematosus.
Topics: Kidney Diseases; Lupus Erythematosus, Systemic; Lymph Nodes; Procainamide | 1970 |
1 trial available for procainamide and Lupus Erythematosus, Systemic
| Article | Year |
|---|---|
Anti-[(H2A/2B)-DNA]] IgG supports the diagnosis of procainamide-induced arthritis or pleuritis.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Antibodies, Antinuclear; DNA; Enzyme-Linked Immunosorbent Assay | 1999 |
240 other studies available for procainamide and Lupus Erythematosus, Systemic
| Article | Year |
|---|---|
Drug-induced systemic lupus: revisiting the ever-changing spectrum of the disease using the WHO pharmacovigilance database.
Topics: Adalimumab; Adult; Antirheumatic Agents; Databases, Factual; Etanercept; Female; Humans; Hydralazine | 2019 |
Molecular organization of the non-bilayer phospholipid arrangements that induce an autoimmune disease resembling human lupus in mice.
Topics: Animals; Antibodies; Antibodies, Monoclonal; Cardiolipins; Cattle; Chlorpromazine; Kidney Glomerulus | 2012 |
Demethylation of ITGAL (CD11a) regulatory sequences in systemic lupus erythematosus.
Topics: Adult; Autoimmunity; Azacitidine; Cells, Cultured; DNA Methylation; Enzyme Inhibitors; Female; Gene | 2002 |
Hydralazine may induce autoimmunity by inhibiting extracellular signal-regulated kinase pathway signaling.
Topics: Animals; Autoimmunity; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine- | 2003 |
Procainamide-induced lupus erythematosus.
Topics: Humans; Lupus Erythematosus, Systemic; Procainamide | 1962 |
SYSTEMIC LUPUS ERYTHEMATOSUS ASSOCIATED WITH PROCAINAMIDE THERAPY.
Topics: Humans; Lupus Erythematosus, Systemic; Procainamide; Toxicology | 1964 |
LUPUS-LIKE ILLNESS PRECIPITATED BY PROCAINAMIDE HYDROCHLORIDE.
Topics: Arrhythmias, Cardiac; Autoimmune Diseases; Coombs Test; Diagnosis; Digoxin; Drug Therapy; Geriatrics | 1965 |
PROCAINAMIDE AND LUPUS ERYTHEMATOSUS.
Topics: Humans; Lupus Erythematosus, Systemic; Procainamide | 1965 |
LUPUS-LIKE SYNDROME INDUCED BY PROCAINE AMIDE: ASSOCIATION WITH ANTI-DNA ANTIBODY.
Topics: Antibodies; Antibodies, Anti-Idiotypic; Antibodies, Antinuclear; Diagnosis; DNA; Drug Hypersensitivi | 1965 |
Overexpression of CD70 and overstimulation of IgG synthesis by lupus T cells and T cells treated with DNA methylation inhibitors.
Topics: Adult; Aged; Antigens, CD; Azacitidine; B-Lymphocytes; CD27 Ligand; DNA Methylation; Enzyme Inhibito | 2004 |
Demethylation of the same promoter sequence increases CD70 expression in lupus T cells and T cells treated with lupus-inducing drugs.
Topics: 5' Flanking Region; Adult; Antigens, CD; Base Sequence; CD27 Ligand; Cells, Cultured; DNA Methylatio | 2005 |
Quinidine and procainamide inhibit murine macrophage uptake of apoptotic and necrotic cells: a novel contributing mechanism of drug-induced-lupus.
Topics: Animals; Apoptosis; Flow Cytometry; Lupus Erythematosus, Systemic; Macrophages, Peritoneal; Mice; Mi | 2005 |
Bilateral Mondor's disease.
Topics: Adult; Breast Diseases; Female; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Procainami | 1967 |
Vasculitis following procaine amide therapy.
Topics: Autoimmune Diseases; Drug Hypersensitivity; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged | 1967 |
Procainamide HCl-induced lupus syndrome in a child with myotonia congenita.
Topics: Child, Preschool; Female; Humans; Lupus Erythematosus, Systemic; Myotonia Congenita; Procainamide | 1967 |
Lupus-like syndrome induced by procainamide.
Topics: Arrhythmias, Cardiac; Female; Humans; Lupus Erythematosus, Systemic; Middle Aged; Procainamide; Prop | 1967 |
Systemic lupus erythematosus associated with procainamide.
Topics: Aged; Heart Block; Humans; Lupus Erythematosus, Systemic; Male; Myocardial Infarction; Procainamide | 1967 |
The epidemiology of drug-induced systemic lupus erythematosus.
Topics: Adolescent; Adult; Aged; Child; Epilepsy; Female; Heart Diseases; Humans; Hydralazine; Hypertension; | 1967 |
Studies of autologous mixed lymphocyte reactions in patients with systemic lupus erythematosus.
Topics: Adult; Aged; Antibodies; DNA; Female; Humans; Immunosuppressive Agents; Liver Cirrhosis, Biliary; Lu | 1983 |
Drug allergy--problems and strategies.
Topics: Anaphylaxis; Anemia, Hemolytic; Antigen-Antibody Complex; Desensitization, Immunologic; Dose-Respons | 1984 |
Procainamide, NAPA and systemic lupus.
Topics: Acecainide; Animals; Dogs; Humans; Lupus Erythematosus, Systemic; Procainamide | 1980 |
Procainamide-induced lupus erythematosus pericarditis encountered during coronary bypass sugery.
Topics: Biopsy; Coronary Artery Bypass; Humans; Intraoperative Complications; Lupus Erythematosus, Systemic; | 1980 |
Efficacy, plasma concentrations and adverse effects of a new sustained release procainamide preparation.
Topics: Acecainide; Acetylation; Adult; Aged; Anti-Arrhythmia Agents; Antibodies, Antinuclear; Arrhythmias, | 1980 |
Alter drug structure--avert induced lupus.
Topics: Acecainide; Arrhythmias, Cardiac; Female; Humans; Lupus Erythematosus, Systemic; Male; Procainamide; | 1981 |
The chemical induction of systemic lupus erythematosus and lupus-like illnesses.
Topics: Acecainide; Acetylation; Adult; Female; Humans; Hydralazine; Hydrazines; Isoniazid; Lupus Erythemato | 1981 |
Procainamide-lymphocyte reactions. A possible explanation for drug-induced autoimmunity.
Topics: Aged; Animals; Antibody-Producing Cells; Antilymphocyte Serum; Autoimmune Diseases; Epitopes; Female | 1981 |
The implications of procainamide metabolism to its induction of lupus.
Topics: Acecainide; Acetylation; Animals; Antibodies, Antinuclear; Antibody Formation; Humans; Hydroxylamine | 1981 |
Studies on a circulating anticoagulant in procainamide-induced lupus erythematosus.
Topics: Aged; Blood Coagulation; Blood Coagulation Tests; gamma-Globulins; Humans; Immunoglobulin M; Immunog | 1981 |
Inhibition of Con A mitogenesis by serum from procainamide-treated patients and patients with systemic lupus erythematosus.
Topics: Acecainide; Antibodies; Binding, Competitive; Concanavalin A; Humans; Immunoglobulin G; In Vitro Tec | 1982 |
Aromatic amines and the pathogenesis of lupus erythematosus.
Topics: Acecainide; Acetylation; Amines; Anti-Arrhythmia Agents; Humans; Hydrazines; Lupus Erythematosus, Sy | 1983 |
Immune regulatory abnormalities produced by procainamide.
Topics: Adolescent; Adult; Aged; Antibodies, Antinuclear; Autoantibodies; Concanavalin A; DNA, Single-Strand | 1982 |
Drug-induced rheumatic diseases.
Topics: Adrenal Cortex Hormones; Anticonvulsants; Antineoplastic Agents; Diuretics; Gout; Heparin; Humans; H | 1984 |
Reactive hypoglycemia and insulin autoantibodies in drug-induced lupus erythematosus.
Topics: Aged; Autoantibodies; Autoimmune Diseases; Female; Glucose Tolerance Test; Humans; Hydralazine; Hypo | 1983 |
Autoallergic reactions induced by procainamide.
Topics: Acetylation; Antibodies, Antinuclear; Antibody Formation; Antibody Specificity; Autoantibodies; Auto | 1984 |
The prevalence of antibodies to histones induced by procainamide in old people, in cancer patients, and in rheumatoid-like disease.
Topics: Adolescent; Adult; Aged; Aging; Antibodies, Antinuclear; Arthritis; Female; Histones; Humans; Lupus | 1983 |
Procainamide-induced lupus lung disease characterized by neutrophil alveolitis.
Topics: Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Neutrophils; Pneumonia; Procainamide; Pulm | 1984 |
Accelerated constrictive pericarditis in procainamide-induced systemic lupus erythematosus.
Topics: Cardiac Catheterization; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Pericarditis, Con | 1984 |
[Drug-induced lupus erythematosus syndrome. Pathogenesis and relation to systemic lupus erythematosus].
Topics: Diagnosis, Differential; Drug-Related Side Effects and Adverse Reactions; Humans; Hydralazine; Lupus | 1984 |
Prekallikrein inhibition associated with the lupus anticoagulant: a mechanism of thrombosis.
Topics: Adolescent; Adult; Autoimmune Diseases; Blood Coagulation Factors; Female; Femoral Vein; Fibrinolysi | 1982 |
Reticulocytopenic, coombs' positive anemia induced by procainamide.
Topics: Anemia, Hemolytic; Coombs Test; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Procainami | 1983 |
Low-dose procainamide: low risk of complications with long-term use.
Topics: Adult; Aged; Coronary Disease; Female; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Pro | 1983 |
SLE: idiopathic or drug-induced?
Topics: Adult; Aged; Antibodies, Antinuclear; Autoantibodies; Central Nervous System Diseases; DNA; Drug-Rel | 1980 |
Large dose procainamide therapy for ventricular tachyarrhythmia.
Topics: Adult; Aged; Anorexia; Antibodies, Antinuclear; Arrhythmias, Cardiac; Dose-Response Relationship, Dr | 1980 |
[Procainamide-induced lupus erythematosus].
Topics: Adult; Aged; Antibodies, Antinuclear; Female; Humans; Lupus Erythematosus, Systemic; Male; Middle Ag | 1980 |
Antinuclear antibodies related to acetylator phenotype in mice.
Topics: Acetylation; Acetyltransferases; Animals; Antibodies, Antinuclear; Female; Lupus Erythematosus, Syst | 1980 |
Disopyramide and antinuclear antibodies.
Topics: Adult; Aged; Antibodies, Antinuclear; Disopyramide; Female; Humans; Lupus Erythematosus, Systemic; M | 1981 |
Drug effects on autoantibodies and immune complexes.
Topics: Acetylation; Antibodies, Antinuclear; Antigen-Antibody Complex; Arthritis, Rheumatoid; Autoantibodie | 1980 |
Pharmacokinetic studies on the drug-related lupus syndrome. Differences in antinuclear antibody development and drug-induced DNA damage in rapid and slow acetylator animal models.
Topics: Acetylation; Animals; Antibodies, Antinuclear; Antibody Formation; Disease Models, Animal; DNA Repai | 1981 |
Renal manifestations of drug-induced systemic lupus erythematosus.
Topics: Biopsy; Fluorescent Antibody Technique; Glomerulonephritis; Humans; Kidney; Lupus Erythematosus, Sys | 1981 |
The role of histones as nuclear autoantigens in drug-related lupus erythematosus.
Topics: Animals; Antibodies, Antinuclear; Antibody Formation; Antibody Specificity; Antigens; Autoantigens; | 1981 |
Update on quinidine and procainamide.
Topics: Arrhythmias, Cardiac; Digestive System; Drug Interactions; Heart; Humans; Lupus Erythematosus, Syste | 1982 |
Drug-related lupus.
Topics: Humans; Hydralazine; Lupus Erythematosus, Systemic; Procainamide | 1982 |
[Procainamide-induced lupus with circulating anticoagulant].
Topics: Blood Coagulation; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Procainamide | 1982 |
Systemic lupus erythematosus during treatment with procainamide.
Topics: Female; Humans; Lupus Erythematosus, Systemic; Procainamide | 1982 |
Drug history is important.
Topics: Adult; Female; Humans; Lupus Erythematosus, Systemic; Medical History Taking; Procainamide; Tachycar | 1981 |
Introduction to drug-related lupus.
Topics: Acetylation; Acetyltransferases; Animals; Anticonvulsants; Autoimmune Diseases; Child; Chlorpromazin | 1981 |
Hapten immunology and allergic reactions in humans.
Topics: Animals; Autoimmune Diseases; Carrier Proteins; Drug Hypersensitivity; Environmental Health; Haptens | 1981 |
Procainamide-induced myositis.
Topics: Aged; Humans; Lupus Erythematosus, Systemic; Male; Muscles; Myositis; Procainamide | 1980 |
Mechanism of drug-induced lupus. I. Cloned Th2 cells modified with DNA methylation inhibitors in vitro cause autoimmunity in vivo.
Topics: Animals; Autoantibodies; Azacitidine; Cell Line; Cytokines; Cytotoxicity, Immunologic; DNA; Enzyme-L | 1995 |
Epitope mapping of histone 5 (H5) with systemic lupus erythematosus, procainamide-induced lupus and hydralazine-induced lupus sera.
Topics: Amino Acid Sequence; Antibody Specificity; Autoantibodies; Blotting, Western; Epitopes; Histones; Hu | 1993 |
Treating activated CD4+ T cells with either of two distinct DNA methyltransferase inhibitors, 5-azacytidine or procainamide, is sufficient to cause a lupus-like disease in syngeneic mice.
Topics: Animals; Antigen-Presenting Cells; Azacitidine; CD4-Positive T-Lymphocytes; DNA (Cytosine-5-)-Methyl | 1993 |
Arty-crafty fact of life?
Topics: Acetaminophen; Cytotoxins; Humans; Lupus Erythematosus, Systemic; Neutrophils; Pharmaceutical Prepar | 1995 |
IgG but not other classes of anti-[(H2A-H2B)-DNA] is an early sign of procainamide-induced lupus.
Topics: Antibodies, Antinuclear; Arrhythmias, Cardiac; B-Lymphocytes; DNA; Histones; Humans; Immunoglobulin | 1995 |
Transformation of lupus-inducing drugs to cytotoxic products by activated neutrophils.
Topics: Animals; Biological Assay; Biotransformation; Cell Death; Chlorpromazine; Humans; Hydralazine; Hydro | 1994 |
Antibodies to dsDNA in drug induced lupus erythematosus.
Topics: Antibodies, Antinuclear; Artifacts; DNA; Humans; Hydralazine; Lupus Erythematosus, Systemic; Nucleic | 1994 |
Study of procainamide hapten-specific antibodies in rabbits and humans.
Topics: Adult; Aged; Aged, 80 and over; Animals; Antibody Specificity; Autoantibodies; Collagen; Female; Hap | 1993 |
[A case of primary antiphospholipid antibody syndrome associated with procainamide induced systemic lupus erythematosus].
Topics: Aged; Anti-Arrhythmia Agents; Antibodies, Antiphospholipid; Antiphospholipid Syndrome; Female; Human | 1995 |
Autoimmunity caused by disruption of central T cell tolerance. A murine model of drug-induced lupus.
Topics: Adoptive Transfer; Animals; Antibodies, Antinuclear; Autoimmunity; Disease Models, Animal; Female; H | 1997 |
A metabolite of the lupus-inducing drug procainamide prevents anergy induction in T cell clones.
Topics: Animals; Clonal Anergy; Immune Tolerance; Lupus Erythematosus, Systemic; Lymphocyte Activation; Mice | 1997 |
Mechanisms of drug-induced lupus. III. Sex-specific differences in T cell homing may explain increased disease severity in female mice.
Topics: Adoptive Transfer; Animals; Antibodies, Antinuclear; Autoantibodies; Autoimmune Diseases; Chemical a | 1997 |
[Procainamide-induced lupus in a patient with bilateral pleural effusion].
Topics: Aged; Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Autoantibodies; Enzyme-Linked Immunosorbent | 1998 |
Rapid development of drug-induced lupus nephritis in the absence of extrarenal disease in a patient receiving procainamide.
Topics: Aged; Anti-Arrhythmia Agents; Biopsy; Diagnosis, Differential; Humans; Kidney; Lupus Erythematosus, | 1998 |
Systemic sclerosis complicated by procainamide-induced lupus and antiphospholipid syndrome.
Topics: Anti-Arrhythmia Agents; Antiphospholipid Syndrome; Arrhythmias, Cardiac; Foot Diseases; Gangrene; Hu | 1998 |
Procainamide, a drug causing lupus, induces prostaglandin H synthase-2 and formation of T cell-sensitizing drug metabolites in mouse macrophages.
Topics: Animals; Arylamine N-Acetyltransferase; Enzyme Induction; Female; Isoenzymes; Lupus Erythematosus, S | 1999 |
In vitro production of antibodies to histones in patients receiving chronic procainamide therapy.
Topics: Adult; Aged; Antibodies, Antinuclear; Arrhythmias, Cardiac; Autoantibodies; Autoimmunity; Cells, Cul | 2001 |
Thymus function in drug-induced lupus.
Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Autoantibodies; Base Sequence; Chromatin; Female | 2001 |
Clinical consequences of polymorphic acetylation of basic drugs.
Topics: Acetylation; Antibodies, Antinuclear; Biotransformation; Chemical and Drug Induced Liver Injury; Hum | 1977 |
Drug-induced systemic lupus erythematosus.
Topics: Anticonvulsants; Antihypertensive Agents; Antipsychotic Agents; Antitubercular Agents; Female; Human | 1978 |
[Lupos erythematosus discovered during the course of a toxicodermia (author's transl)].
Topics: Adult; Aged; Ampicillin; Aprindine; Drug Eruptions; Female; Humans; Lupus Erythematosus, Systemic; M | 1979 |
Procainamide-induced lupus syndrome in siblings.
Topics: Aged; Antibodies, Antinuclear; Atrial Fibrillation; Bundle-Branch Block; Female; Humans; Lupus Eryth | 1975 |
Effects of long-term treatment with procaine amide. A prospective study with special regard to ANF and SLE in fast and slow acetylators.
Topics: Acetylation; Adult; Aged; Antibodies, Antinuclear; Arrhythmias, Cardiac; Female; Humans; Lupus Eryth | 1975 |
Drug-induced lupus erythematosus.
Topics: Aged; Antibodies, Antinuclear; Arrhythmias, Cardiac; Humans; Lupus Erythematosus, Systemic; Male; Ne | 1977 |
Lupus erythematosus cells in pleural effusion: the initial manifestation of procainamide-induced lupus erythematosus.
Topics: Antibodies, Antinuclear; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Myocardial Infarc | 1977 |
Drug-induced lupus erythematosus with in vivo lupus erythematosus cells in pleural fluid.
Topics: Aged; Humans; Lupus Erythematosus, Systemic; Male; Neutrophils; Pleural Effusion; Procainamide | 1978 |
LE cells in pleural fluid.
Topics: Aged; Female; Humans; Hydralazine; Lupus Erythematosus, Systemic; Neutrophils; Pleural Effusion; Pro | 1979 |
Lymphocyte alteration by procainamide: relation to drug-induced lupus erythematosus syndrome.
Topics: Aged; Antibodies, Antinuclear; Antilymphocyte Serum; Cell Membrane; Cytotoxicity, Immunologic; Human | 1979 |
Procainamide, acetylprocainamide, and drug-induced lupus erythematosus.
Topics: Acecainide; Humans; Immune Complex Diseases; Lupus Erythematosus, Systemic; Procainamide | 1979 |
Antibodies to nuclear antigens in patients treated with procainamide or acetylprocainamide.
Topics: Acecainide; Aged; Antibodies, Antinuclear; Antibody Formation; Cell Nucleus; DNA; DNA, Single-Strand | 1979 |
Procainamide-induced lupus erythematosus-like syndrome in relation to acetylator phenotype and plasma levels of procainamide.
Topics: Acecainide; Acetylation; Adult; Aged; Antibodies, Antinuclear; Female; Humans; Isoniazid; Lupus Eryt | 1979 |
Procainamide-induced lupus.
Topics: Aged; Arrhythmias, Cardiac; Cardiomegaly; Drainage; Drug Therapy, Combination; Factor XI Deficiency; | 1976 |
Atypical lupus-like syndrome following prolonged pronestyl administration.
Topics: Aged; Humans; Long-Term Care; Lupus Erythematosus, Systemic; Male; Procainamide | 1975 |
[Clinical and immunological study of 2 homozygotic twins of which 1 had disseminated lupus erythematosus caused by procainamide].
Topics: Aged; Autoimmune Diseases; Diseases in Twins; Female; Humans; Lupus Erythematosus, Systemic; Procain | 1977 |
Drug-induced systemic lupus erythematosus.
Topics: Digoxin; Humans; Hydrochlorothiazide; Lupus Erythematosus, Systemic; Male; Middle Aged; Procainamide | 1977 |
Phospholipid monolayers and systemic lupus erythematosus.
Topics: Anesthetics, Local; Humans; Lupus Erythematosus, Systemic; Procainamide; Pulmonary Surfactants; Surf | 1977 |
[Procainamide- and quinidine-induced immunological changes].
Topics: Antibodies, Antinuclear; Arrhythmias, Cardiac; Humans; Immunoglobulins; Lupus Erythematosus, Systemi | 1977 |
ANA, DNA, and SLE.
Topics: Animals; Antibodies, Antinuclear; Autoimmune Diseases; DNA; Humans; Hydralazine; Lupus Erythematosus | 1977 |
[Disseminated lupus erythematosus: etiopathogenic factors].
Topics: Animals; Antibodies; Autoantibodies; B-Lymphocytes; Female; Humans; Hydantoins; Hydralazine; Isoniaz | 1977 |
Effect of acetylator phenotype on the rate at which procainamide induces antinuclear antibodies and the lupus syndrome.
Topics: Acetylation; Adult; Aged; Antibodies, Antinuclear; Biotransformation; History, 18th Century; Humans; | 1978 |
Remission of procainamide-induced lupus erythematosus with N-acetylprocainamide therapy.
Topics: Antibodies, Antinuclear; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Procainamide | 1979 |
Antibodies to histones in drug-induced and idiopathic lupus erythematosus.
Topics: Antibodies, Antinuclear; Antibody Specificity; Cell Nucleus; Fluorescent Antibody Technique; Histone | 1978 |
Peripheral blood lymphocytes in systemic lupus erythematosus. Relation to activity.
Topics: Humans; Immunologic Techniques; Lupus Erythematosus, Systemic; Lymphocytes; Mephenytoin; Practolol; | 1977 |
Cryoglobulins in the procainamide-induced lupus syndrome.
Topics: Aged; Cryoglobulins; Humans; Lupus Erythematosus, Systemic; Male; Paraproteinemias; Procainamide | 1979 |
Drug-induced lupus erythematosus.
Topics: Complement System Proteins; Drug-Related Side Effects and Adverse Reactions; Humans; Lupus Erythemat | 1979 |
Nephrotic syndrome in procainamide induced lupus nephritis.
Topics: Aged; Female; Humans; Kidney; Lupus Erythematosus, Systemic; Nephritis; Nephrotic Syndrome; Predniso | 1979 |
[Drug-induced disorders of lupus erythematosus type (author's transl)].
Topics: Animals; Antibody Formation; Anticonvulsants; Chlorpromazine; Drug-Related Side Effects and Adverse | 1977 |
Polyradiculoneuropathy accompanying procainamide-induced lupus erythematosus: evidence for drug-induced enhanced sensitization to peripheral nerve myelin.
Topics: Aged; Angina Pectoris; Animals; Demyelinating Diseases; Drug Hypersensitivity; Humans; Lupus Erythem | 1977 |
Therapy with antiarrhythmic drugs.
Topics: Acetylation; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disopyramide; Heart Failure; Humans; Indo | 1978 |
[New aspects of drug induced lupus erythematosus (author's transl)].
Topics: Adrenal Cortex Hormones; Adult; Aged; Allopurinol; Aspirin; Humans; Lupus Erythematosus, Systemic; M | 1978 |
[Iatrogenic procaine amide-induced lupus with circulating anticoagulant].
Topics: Aged; Blood Coagulation Disorders; Humans; In Vitro Techniques; Lupus Erythematosus, Systemic; Proca | 1978 |
Circulating inhibitors of blood coagulation associated with procainamide-induced lupus erythematosus.
Topics: Blood Coagulation; Blood Coagulation Factors; Blood Coagulation Tests; Factor X; Humans; Immunoglobu | 1978 |
[Lupus erythematosus-like syndrome induced by long-term treatment with procainamide].
Topics: Arrhythmias, Cardiac; Diagnosis, Differential; Humans; Lupus Erythematosus, Systemic; Male; Middle A | 1978 |
Procainamide-induced systemic lupus erythematosus. Renal involvement with deposition of immune complexes.
Topics: Autoantibodies; Fluorescent Antibody Technique; Humans; Iatrogenic Disease; Kidney; Lupus Erythemato | 1976 |
Procainamide-induced systemic lupus erythematosus with hypocomplementemia.
Topics: Aged; Complement System Proteins; Digoxin; Female; Humans; Lupus Erythematosus, Systemic; Prednisone | 1977 |
Lupus syndrome induced by procainamide.
Topics: Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Procainamide | 1977 |
[Drug-induced systemic lupus erythematosus (author's transl)].
Topics: Adolescent; Aged; Anti-Bacterial Agents; Antibody Formation; Autoantibodies; Child; Chlorpromazine; | 1977 |
Circulating anticoagulant in the procainamide-induced lupus syndrome.
Topics: Aged; Arrhythmias, Cardiac; Blood Coagulation; Diagnosis, Differential; Factor XI; Fibrin Fibrinogen | 1977 |
Clinicopathological study of a patient with procainamide-induced systemic lupus erythematosus.
Topics: Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Procainamide; Tachycardia, Paroxysmal | 1976 |
[Drug-induced lupus erythematosus-like syndromes].
Topics: Adolescent; Adult; Aged; Antibodies, Antinuclear; Anticonvulsants; Drug-Related Side Effects and Adv | 1976 |
Pericardial tamponade. A presenting manifestation of procainamide-induced lupus erythematosus.
Topics: Aged; Cardiac Tamponade; Humans; Lupus Erythematosus, Systemic; Male; Pericardial Effusion; Pericard | 1975 |
Constrictive pericarditis in procainamide-induced lupus erythematosus syndrome.
Topics: Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Pericarditis, Constrictive; Prednisone; Pr | 1975 |
Letter: Acute pancreatitis due to procainamide-induced lupus erythematosus.
Topics: Acute Disease; Aged; Humans; Lupus Erythematosus, Systemic; Male; Pancreatitis; Procainamide | 1975 |
Hypocomplementemia in procainamide-associated systemic lupus erythematosus.
Topics: Antibodies; Complement System Proteins; DNA; Humans; Lupus Erythematosus, Systemic; Male; Middle Age | 1976 |
Drug-induced lupus.
Topics: Acebutolol; Adult; Aged; Antibodies, Antinuclear; Blood Sedimentation; Female; Humans; Lupus Erythem | 1992 |
Autoantibody specificity in drug-induced lupus and neutrophil-mediated metabolism of lupus-inducing drugs.
Topics: Antibody Specificity; Autoantibodies; Chromatin; Histones; Humans; Hydralazine; Lupus Erythematosus, | 1992 |
Lupus-inducing drugs alter the structure of supercoiled circular DNA domains.
Topics: Acecainide; Animals; Antibodies; Canavanine; DNA, Superhelical; Electrophoresis, Agar Gel; Escherich | 1990 |
Antibodies from patients with systemic lupus erythematosus and drug-induced lupus bind determinants on histone 5 (H5).
Topics: Amino Acid Sequence; Animals; Autoantibodies; Chickens; Cross Reactions; Epitopes; Histones; Humans; | 1990 |
Drug-induced lupus pleuritis mimicking pleural space infection.
Topics: Acute Disease; Aged; Diagnosis, Differential; Humans; Infections; Lupus Erythematosus, Systemic; Mal | 1992 |
Procainamide-induced pleural fibrosis.
Topics: Aged; Fibrosis; Humans; Lupus Erythematosus, Systemic; Male; Pleura; Procainamide | 1991 |
Purification of histone H1 polypeptides by high-performance cation-exchange chromatography.
Topics: Animals; Bromosuccinimide; Cattle; Chromatography, Liquid; Chymotrypsin; Enzyme-Linked Immunosorbent | 1990 |
Anti-histone antibodies in idiopathic and drug-induced lupus recognize distinct intrahistone regions.
Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Autoantibodies; Epitopes; Histones; Humans; H | 1987 |
Procainamide, N-acetylprocainamide, antinuclear antibody and systemic lupus erythematosus.
Topics: Acecainide; Acetylation; Antibodies, Antinuclear; Humans; Lupus Erythematosus, Systemic; Procainamid | 1986 |
Autoantigenic histone epitopes: a comparison between procainamide- and hydralazine-induced lupus.
Topics: Autoantigens; Epitopes; Histones; Humans; Hydralazine; Lupus Erythematosus, Systemic; Procainamide | 1987 |
Procainamide-induced circulating anticoagulants in a congenitally-deficient factor XI patient.
Topics: Aged; Blood Coagulation Factors; Blood Coagulation Tests; Coronary Artery Bypass; Factor XI Deficien | 1989 |
Pulmonary thromboembolism associated with procainamide induced lupus syndrome and anticardiolipin antibodies.
Topics: Aged; Autoantibodies; Blood Coagulation Factors; Cardiolipins; Humans; Lupus Coagulation Inhibitor; | 1989 |
Immunomodulatory effects of procainamide metabolites: their implications in drug-related lupus.
Topics: Adult; Female; Hemoglobins; Humans; Immunoglobulins; Interleukin-1; Latex; Leukocytes, Mononuclear; | 1989 |
Thrombocytopenia following sustained-release procainamide.
Topics: Acecainide; Acetylation; Adult; Aged; Antibodies, Antinuclear; Delayed-Action Preparations; Humans; | 1985 |
Synovial fluid characteristics and the lupus erythematosus cell phenomenon in drug-induced lupus. Findings in three patients and review of pertinent literature.
Topics: Adult; Aged; Female; Humans; Lupus Erythematosus, Systemic; Male; Mephenytoin; Middle Aged; Procaina | 1989 |
Cardiac tamponade associated with drug-induced systemic lupus erythematosus.
Topics: Cardiac Tamponade; Female; Humans; Lupus Erythematosus, Systemic; Middle Aged; Procainamide | 1989 |
Seek and find.
Topics: Cardiac Tamponade; Humans; Lupus Erythematosus, Systemic; Procainamide | 1989 |
Procainamide-DNA interaction.
Topics: Animals; Darkness; DNA; DNA Damage; DNA Polymerase I; DNA Repair; Endonucleases; Light; Lupus Erythe | 1988 |
Association of antibody to histone complex H2A-H2B with symptomatic procainamide-induced lupus.
Topics: Aged; Aged, 80 and over; Antibodies, Antinuclear; Cardiolipins; Enzyme-Linked Immunosorbent Assay; F | 1988 |
Drug-related lupus.
Topics: Antibodies, Antinuclear; Histones; Humans; Lupus Erythematosus, Systemic; Procainamide | 1988 |
Drug-induced lupus.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Antinuclear; Humans; Lupus Erythematosus, | 1988 |
B cell activation in patients with active procainamide induced lupus.
Topics: Aged; B-Lymphocytes; Cells, Cultured; Female; Humans; Lupus Erythematosus, Systemic; Lymphocyte Acti | 1988 |
Antibodies in procainamide-induced and systemic lupus erythematosus bind the C-terminus of histone 1 (H1).
Topics: Amino Acids; Antibodies, Antinuclear; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbe | 1987 |
[Procainamide- and hydralazine-induced antinuclear antibodies in Japanese].
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Antinuclear; Asian People; Female; Humans; Hydralazine; | 1987 |
Antiguanosine antibodies: a new marker for procainamide-induced systemic lupus erythematosus.
Topics: Adult; Aged; Antibodies, Antinuclear; DNA, Single-Stranded; Female; Fluorescent Antibody Technique; | 1986 |
Increased presence of common systemic lupus erythematosus (SLE) anti-DNA idiotypes (16/6 Id, 32/15 Id) is induced by procainamide.
Topics: Antibodies, Viral; Antibody Formation; Antigen-Antibody Complex; DNA; Enzyme-Linked Immunosorbent As | 1987 |
Serologic changes during induction of lupus-like disease by procainamide.
Topics: Aged; Antibodies; Complement Activation; Histones; Humans; Lupus Erythematosus, Systemic; Male; Panc | 1986 |
[A erythematosus-like syndrome caused by procainamide].
Topics: Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Procainamide | 1986 |
Effects of lupus-inducing drugs on the B to Z transition of synthetic DNA.
Topics: Canavanine; Circular Dichroism; DNA; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Nucleic | 1986 |
IgG subclasses of autoantibodies in systemic lupus erythematosus, Sjogren's syndrome, and drug-induced autoimmunity.
Topics: Antibodies, Monoclonal; Autoantibodies; Autoimmune Diseases; DNA; Enzyme-Linked Immunosorbent Assay; | 1986 |
[Systemic lupus erythematosus diagnosed after 12 years' treatment with procainamide].
Topics: Female; Humans; Lupus Erythematosus, Systemic; Middle Aged; Procainamide; Time Factors | 1986 |
Anti-histones.
Topics: Antibodies, Monoclonal; Arthritis, Rheumatoid; Autoantibodies; Binding Sites, Antibody; Binding, Com | 1985 |
IgG antibodies to the histone complex H2A-H2B characterize procainamide-induced lupus.
Topics: Adult; Aged; Antibodies, Anti-Idiotypic; Antibody Specificity; Autoantibodies; Female; Histones; Hum | 1985 |
Drug-induced lupus. Genetic, clinical, and laboratory features.
Topics: Aged; Antibodies, Antinuclear; Diagnosis, Differential; Humans; Hydralazine; Immunoglobulins; Lupus | 1985 |
The diagnostic value of antihistone antibodies in drug-induced lupus erythematosus.
Topics: Adolescent; Adult; Aged; Antibodies, Antinuclear; Autoantibodies; Child; Disopyramide; Female; Fluor | 1985 |
Antinuclear antibodies as indicators for the procainamide-induced systemic lupus erythematosus-like syndrome and its clinical presentations.
Topics: Antibodies, Antinuclear; Antibody Specificity; Antigens; Antigens, Nuclear; Arrhythmias, Cardiac; De | 1985 |
Procainamide, quinidine, and lupus erythematosus.
Topics: Aged; Female; Humans; Lupus Erythematosus, Systemic; Procainamide; Quinidine | 1985 |
Quinidine induced lupus syndrome.
Topics: Aged; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Procainamide; Quinidine; Thrombocyto | 1985 |
Procainamide-induced lupus-like syndrome.
Topics: Aged; Antibodies, Antinuclear; Arrhythmias, Cardiac; Female; Humans; Lupus Erythematosus, Systemic; | 1970 |
Systemic lupus erythematosus induced by procaine amide.
Topics: Aged; Antibodies, Antinuclear; Arrhythmias, Cardiac; Blood Proteins; Blood Sedimentation; Humans; Im | 1970 |
Occurrence, immunoglobulin pattern and specificity of antinuclear antibodies in sera of procaine amide treated patients.
Topics: Adolescent; Adult; Aged; Antibodies, Antinuclear; Antibody Formation; Arrhythmias, Cardiac; Coronary | 1970 |
Failure of procainamide to induce a systemic lupus erythematosus-like disease in animals.
Topics: Animals; Antibodies, Antinuclear; Blood Cell Count; Blood Volume Determination; Body Weight; Criceti | 1972 |
[Drug-induced lupus erythematosus disseminatus].
Topics: Anti-Arrhythmia Agents; Anti-Bacterial Agents; Anti-Inflammatory Agents; Anticonvulsants; Antihypert | 1972 |
The frequency of procainamide-induced systemic lupus erythematosus.
Topics: Adult; Aged; Antibodies, Antinuclear; Arrhythmias, Cardiac; Coombs Test; Female; Hemagglutination Te | 1972 |
Current status of the LE cell test.
Topics: Animals; Antibodies, Antinuclear; Complement System Proteins; Guinea Pigs; Humans; Immunoglobulin G; | 1971 |
Complement-fixing activity of antinuclear antibodies induced by procaine amide treatment.
Topics: Animals; Antibodies, Antinuclear; Cattle; Complement Fixation Tests; Complement System Proteins; Flu | 1973 |
Connective-tissue effects of drugs causing lupoid syndrome.
Topics: Animals; Carbon Radioisotopes; Chick Embryo; Chlorpromazine; Collagen; Depression, Chemical; Glucosa | 1974 |
Drug-induced autoimmune disease.
Topics: Acetyltransferases; Antibodies, Antinuclear; Antibody Specificity; Autoimmune Diseases; Binding Site | 1974 |
Drug-induced lupus erythematosus syndrome. Immuno-pathological, electronmicroscopical and serological studies.
Topics: Adult; Animals; Antibodies, Antinuclear; Biopsy; Complement Fixation Tests; Female; Fluorescent Anti | 1974 |
Letter: Aetiology of systemic lupus erythematosus.
Topics: Acetylation; Antibody Formation; DNA; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; | 1974 |
Case report: lupus-like syndrome with positive Hargrave phenomenon induced by pronestyl therapy: analysis of the test.
Topics: Diagnosis, Differential; Female; Humans; Lupus Erythematosus, Systemic; Middle Aged; Neutrophils; Pr | 1965 |
Procainamide hydrochloride and lupus erythematosus.
Topics: Aged; Dexamethasone; Diagnosis, Differential; Electrocardiography; Female; Humans; Joint Diseases; L | 1965 |
Lupus-like syndrome induced by procainamide.
Topics: Adult; Aged; Antibodies, Antinuclear; Atrial Fibrillation; Atrial Flutter; Autoantibodies; Fluoresce | 1967 |
A familial study of procainamide-induced systemic lupus erythematosus. A question of pharmacogenetic polymorphism.
Topics: Antibodies, Antinuclear; Arthritis; Autoantibodies; Female; Fluorescent Antibody Technique; Humans; | 1968 |
Procainamide-induced systemic lupus erythematosus.
Topics: Antibodies, Antinuclear; Female; Humans; Lupus Erythematosus, Systemic; Middle Aged; Neutrophils; Pr | 1969 |
Antinuclear antibody induced by procainamide. A prospective study.
Topics: Adult; Aged; Antibodies, Antinuclear; Arrhythmias, Cardiac; Autoantibodies; Complement System Protei | 1969 |
[The reversible procaine amide-induced lupus-erythromatosus syndrome].
Topics: Aged; Antibodies; Antibodies, Antinuclear; Biopsy; Corticosterone; Female; Histocytochemistry; Human | 1969 |
[Procaine-induced lupus erythematosus].
Topics: Aged; Antibodies, Antinuclear; Arthritis; Blood Sedimentation; Female; Heart Diseases; Humans; Lupus | 1970 |
Procainamide-induced systemic lupus erythematosus.
Topics: Aged; Angina Pectoris; Antibodies, Anti-Idiotypic; Antibodies, Antinuclear; Arrhythmias, Cardiac; Bl | 1970 |
Procainamide induced lupus diathesis.
Topics: Adult; Aged; Cardiac Complexes, Premature; Humans; Lupus Erythematosus, Systemic; Male; Procainamide | 1968 |
When a drug is the culprit.
Topics: Adult; Aged; Angina Pectoris; Arrhythmias, Cardiac; Clofibrate; Depression; Drug-Related Side Effect | 1973 |
The interaction of lupus-inducing drugs with deoxyribonucleic acid.
Topics: Adult; Animals; Cattle; Child; DNA; DNA, Single-Stranded; Hot Temperature; Humans; Hydralazine; Immu | 1974 |
The chest roentgenographic manifestations of Pronestyl-induced lupus erythematosus.
Topics: Aged; Antibodies, Antinuclear; Arrhythmias, Cardiac; Cardiomegaly; Cardiomyopathies; Female; Heart; | 1973 |
[Experimental approach to the pathogenesis of systemic lupus erythematosus].
Topics: Animals; Antigen-Antibody Complex; Autoantibodies; Cyclophosphamide; Disease Models, Animal; DNA; Fe | 1972 |
[Acute lupus erythematosus induced by procainamide].
Topics: Age Factors; Antibodies, Antinuclear; Arthritis; Fever; Heart Diseases; Humans; Lupus Erythematosus, | 1973 |
Morphologic effects of procaine amide on mouse kidney as observed by scanning and by transmission electron microscopy.
Topics: Animals; Basement Membrane; Disease Models, Animal; Female; Kidney Glomerulus; Lupus Erythematosus, | 1974 |
[Drug induced lupus erythematosus disseminatus syndrome].
Topics: Female; Humans; Lupus Erythematosus, Systemic; Male; Procainamide; Registries | 1974 |
Drug-induced arthritis.
Topics: Acute Disease; Anticoagulants; Antihypertensive Agents; Arteritis; Arthritis; Barbiturates; Contrace | 1974 |
Procainamide-induced systemic lupus erythematosus.
Topics: Diagnosis, Differential; Feeding and Eating Disorders; Fever; Heart Diseases; Humans; Lupus Erythema | 1973 |
Procainamide-induced lupus erythematosus.
Topics: Aged; Arrhythmias, Cardiac; Female; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Procai | 1974 |
Procainamide-induced lupus erythematosus. Clinical and laboratory observations.
Topics: Animals; Antibodies, Antinuclear; Antibody Formation; Autoimmune Diseases; Cattle; Complement Fixati | 1972 |
Lupus-like syndrome, with persistent immunological abnormalities, related to procainamide therapy.
Topics: Adult; Antibodies, Antinuclear; Blood Protein Electrophoresis; Female; Humans; Immune System Disease | 1972 |
Antinuclear antibody response to procainamide in man and laboratory animals.
Topics: Adult; Aged; Animals; Antibodies, Antinuclear; Antibody Formation; Female; Guinea Pigs; Humans; Lupu | 1972 |
[Iatrogenic lupus: current status of the question. I. Clinical study and main drugs responsible].
Topics: Antibodies, Antinuclear; Contraceptives, Oral; Diagnosis, Differential; Humans; Hydralazine; Iatroge | 1972 |
Procainamide and lupus erythematosus.
Topics: Adult; Aged; Antibodies, Antinuclear; Female; Humans; Lupus Erythematosus, Systemic; Male; Middle Ag | 1973 |
Drug-induced pulmonary disease.
Topics: Antibodies, Antinuclear; Arrhythmias, Cardiac; Humans; Lung Diseases; Lupus Erythematosus, Systemic; | 1973 |
Medical grand rounds--from the Medical College of Virginia. Drug-induced lupus erythematosus.
Topics: Antibodies, Anti-Idiotypic; Antibodies, Antinuclear; Disease Susceptibility; DNA; DNA, Single-Strand | 1974 |
[Etilogy of SLE in connection with induction of antinuclear factors by various drugs].
Topics: Antibodies, Antinuclear; DNA; DNA Repair; Humans; Isoniazid; Lupus Erythematosus, Systemic; Phenylbu | 1974 |
Studies on drug induced lupus erythematosus in mice. I. Drug induced antinuclear antibodies (ANA).
Topics: Administration, Oral; Animals; Antibodies, Antinuclear; Antibody Formation; Chlorthalidone; Coombs T | 1972 |
Biologic false-positive FTA-ABS test in drug-induced lupus erythematosus.
Topics: Arrhythmias, Cardiac; False Positive Reactions; Fluorescent Antibody Technique; Humans; Lupus Erythe | 1973 |
Studies on drug-induced lupus erythematosus in mice. II. Drug-induced smooth muscle and skeletal muscle antibodies.
Topics: Animals; Antibody Formation; Autoantibodies; Cell Membrane; Chlorthalidone; Fluorescent Antibody Tec | 1973 |
[Drugs as cause of diseases].
Topics: Abnormalities, Drug-Induced; Berlin; Contraceptives, Oral; Cortisone; Drug-Related Side Effects and | 1974 |
In-vivo nuclear localization of immunoglobulins in clinically normal skin in systemic and procainamide-induced lupus erythematosus.
Topics: Adolescent; Adult; Cell Nucleus; Female; Fluorescent Antibody Technique; Humans; Immunoglobulin G; I | 1974 |
Skin immunofluorescence studies on lupus erythematosus and other antinuclear-antibody-positive diseases.
Topics: Antibodies, Antinuclear; Arthritis, Rheumatoid; Biopsy; Connective Tissue Diseases; Fluorescent Anti | 1974 |
[Iatrogenic lupus syndromes].
Topics: Adult; Female; Humans; Isoniazid; Lupus Erythematosus, Systemic; Male; Middle Aged; Procainamide; Sy | 1973 |
[S-thalassemia. Apropos of 40 case reports in Lebanon].
Topics: Electrocardiography; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Myocardial Infarction | 1973 |
Drug-induced lupus syndrome presenting as pericardia effusion.
Topics: Electrocardiography; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Myocardial Infarction | 1973 |
Drug-induced lupus erythematosus.
Topics: Antibodies; Cell Membrane; DNA; Drug Hypersensitivity; Humans; Hydralazine; Isoniazid; Lupus Erythem | 1973 |
Procainamide-induced SLE and lymphoreticular disorders.
Topics: Aortic Diseases; Autopsy; Blindness; Bone Marrow; Digoxin; Drug Therapy, Combination; Heart Diseases | 1974 |
[Medicaments as iatrogenic factors in the onset of lupoid syndromes].
Topics: Adolescent; Adult; Anticonvulsants; Humans; Hydralazine; Iatrogenic Disease; Isoniazid; Lupus Erythe | 1974 |
Drug-induced lupus syndrome.
Topics: Acetylation; Anticonvulsants; Female; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; | 1974 |
[Systemic lupus erythematosus induced by procain amide].
Topics: Arthritis; Female; Fluorescent Antibody Technique; Heart Ventricles; Humans; Lupus Erythematosus, Sy | 1968 |
Immunoglobulin G subclass of human antinuclear antibodies.
Topics: Antibodies, Antinuclear; Complement Fixation Tests; DNA; Immunodiffusion; Immunoglobulin G; Lupus Er | 1970 |
Procainamide induced systemic lupus erythematosus.
Topics: Arrhythmias, Cardiac; Female; Humans; Lupus Erythematosus, Systemic; Male; Procainamide | 1971 |
Systemic lupus erythematosus during treatment with procainamide.
Topics: Adult; Aged; Arrhythmias, Cardiac; Female; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; | 1972 |
Cardiac tamponade in procainamide induced lupus erythematosus.
Topics: Cardiac Tamponade; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Myocardial Infarction; | 1972 |
A morphologic study on the occurrence and distribution of structures resembling viral nucleocapsids in collagen diseases.
Topics: Arthritis, Rheumatoid; Collagen Diseases; Humans; Inclusion Bodies, Viral; Kidney; Kidney Glomerulus | 1972 |
Procainamide-induced pericardial effusion.
Topics: Aged; Arrhythmias, Cardiac; Female; Humans; Lupus Erythematosus, Systemic; Pericardial Effusion; Per | 1972 |
Cardiac arrhythmias and the orthopaedic surgeon.
Topics: Acetylcholine; Adult; Aged; Arrhythmias, Cardiac; Carbon Dioxide; Central Nervous System; Chlorides; | 1972 |
Procainamide-induced systemic lupus erythematosus.
Topics: Aged; Female; Humans; Lupus Erythematosus, Systemic; Middle Aged; Procainamide | 1968 |
Procainamide and the systemic lupus erythematosus-like syndrome.
Topics: Adult; Aged; Arrhythmias, Cardiac; Female; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; | 1971 |
Natural antibody to procainamide and procainamide-induced systematic lupus erythematosus.
Topics: Animals; Antibodies, Antinuclear; Arthritis, Rheumatoid; Autoantibodies; Cricetinae; Dogs; Humans; I | 1969 |
[Procainamid induced "LED" with high ANF-titer].
Topics: Adult; Antibodies, Antinuclear; Female; Humans; Lupus Erythematosus, Systemic; Procainamide | 1970 |
[2 cases of systemic lupus erythematosus caused by procaine amide].
Topics: Aged; Arrhythmias, Cardiac; Female; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Procai | 1970 |
[Lupus erythematosus in the course of treatment with procaine amide: report of a case].
Topics: Antibodies, Antinuclear; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Procainamide; Tim | 1971 |
[Lupus erythematosus syndrome in the course of procainamide treatment].
Topics: Antibodies; Antibodies, Antinuclear; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Muscl | 1971 |
[Disseminated lupus erythomatodes in the course of procaine amide treatment].
Topics: Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Procainamide | 1970 |
Drug-induced lupus syndromes.
Topics: Anticonvulsants; Drug Hypersensitivity; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemi | 1970 |
Procainamide induced systemic lupus erythematous-like syndrome. Report of one case and review of the literature.
Topics: Aged; Humans; Lupus Erythematosus, Systemic; Male; Procainamide | 1971 |
Procainamide-induced L. E. phenomenon.
Topics: Aged; Humans; Lupus Erythematosus, Systemic; Male; Procainamide | 1968 |
[Lupus nephropathy. Diagnosis, evolution and treatment].
Topics: Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Female; Humans; Kidney Diseases; Lupu | 1968 |
[The lupus erythematosus diseminatus syndrome induced by procaine amide].
Topics: Blood Sedimentation; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Procainamide; Radiogr | 1968 |
Natural antibodies to procaine amide.
Topics: Animals; Antibodies; Antibody Formation; Arthritis, Juvenile; Arthritis, Rheumatoid; Cricetinae; Dia | 1968 |
Procainamide induction of a systemic lupus erythematosus-like syndrome. Presentation of six cases, review of the literature, and analysis and followup of reported cases.
Topics: Adult; Aged; Child, Preschool; Female; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Pro | 1969 |
Pulmonary sequelae in procaine amide induced lupus-like syndrome.
Topics: Adult; Diagnosis, Differential; Drug Hypersensitivity; Humans; Lung Diseases; Lupus Erythematosus, S | 1969 |
Drug-induced systemic lupus erythematosus.
Topics: Humans; Hydralazine; Lupus Erythematosus, Systemic; Procainamide | 1969 |
Myotonia, procaine amide, and lupus-like syndrome.
Topics: Adult; Aged; Female; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Myotonic Dystrophy; P | 1966 |
Ventricular tachycardia: treatment with very large doses of procaine amide.
Topics: Arthritis; Electrocardiography; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Procainami | 1966 |