procainamide has been researched along with Kidney Failure, Chronic in 22 studies
Procainamide: A class Ia antiarrhythmic drug that is structurally-related to PROCAINE.
procainamide : A benzamide that is 4-aminobenzamide substituted on the amide N by a 2-(diethylamino)ethyl group. It is a pharmaceutical antiarrhythmic agent used for the medical treatment of cardiac arrhythmias.
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fractional hydrolysis and acetylation of procainamide, acetylation of procainamide-derived p-aminobenzoic acid and plasma hydrolysis of procaine were studied in 20 patients with chronic heart failure (CHF), 20 patients with chronic respiratory insufficiency (CRI) and 20 patients with chronic renal failure (RF)." | 7.66 | Metabolism of procainamide in patients with chronic heart failure, chronic respiratory failure and chronic renal failure. ( du Souich, P; Erill, S, 1978) |
| "A patient with chronic renal failure who experienced symptomatic ventricular tachycardia was treated successfully with procainamide (PA) after numerous dosage adjustments to optimize his clinical response and serum PA and NAPA concentrations." | 3.66 | High-dose procainamide in chronic renal failure. ( Batenhorst, RL; Bottorff, MB; Kuo, CS, 1983) |
| "Two patients with chronic renal failure developed transient sinus node dysfunction requiring insertion of a temporary pacemaker while receiving procainamide to control ventricular arrhythmias." | 3.66 | Procainamide-induced sinus node dysfunction in patients with chronic renal failure. ( Friedman, HS; Kim, HG, 1979) |
| "Fractional hydrolysis and acetylation of procainamide, acetylation of procainamide-derived p-aminobenzoic acid and plasma hydrolysis of procaine were studied in 20 patients with chronic heart failure (CHF), 20 patients with chronic respiratory insufficiency (CRI) and 20 patients with chronic renal failure (RF)." | 3.66 | Metabolism of procainamide in patients with chronic heart failure, chronic respiratory failure and chronic renal failure. ( du Souich, P; Erill, S, 1978) |
| "A 66-year-old female with chronic renal failure received five doses of procainamide and developed marked QT interval prolongation and recurrent episodes of torsades de pointes, which were temporally related to high serum n-acetylprocainamide (NAPA) levels and not to procainamide levels." | 1.27 | Torsades de pointes due to n-acetylprocainamide. ( Stevenson, WG; Weiss, J, 1985) |
| " The procainamide elimination half-life ranged from 6." | 1.27 | Procainamide pharmacokinetics in patients on continuous ambulatory peritoneal dialysis. ( Beirne, GJ; Moorthy, AV; Raehl, CL, 1986) |
| "Procainamide was assayed by spectrophotometry and spectrophotofluorometry." | 1.25 | Elimination of procainamide in end stage renal failure. ( Briggs, WA; Gibson, TP; Lowenthal, DT; Nelson, HA, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Raja, R | 1 |
| Kramer, M | 1 |
| Alvis, R | 1 |
| Goldstein, S | 1 |
| DeLosAngeles, A | 1 |
| Basseches, PJ | 1 |
| DiGregorio, GJ | 1 |
| Ochotny, R | 1 |
| Michałowska, D | 1 |
| Lowicki, Z | 1 |
| Chmara, E | 1 |
| Bottorff, MB | 1 |
| Kuo, CS | 1 |
| Batenhorst, RL | 1 |
| Mathui, N | 1 |
| Nakagawa, S | 1 |
| Takeuchi, J | 1 |
| Stec, GP | 1 |
| Atkinson, AJ | 2 |
| Nevin, MJ | 1 |
| Thenot, JP | 1 |
| Ruo, TI | 1 |
| Gibson, TP | 4 |
| Ivanovich, P | 1 |
| del Greco, F | 1 |
| Kim, HG | 1 |
| Friedman, HS | 1 |
| Nattel, S | 1 |
| Ogilvie, RI | 1 |
| Kreeft, J | 1 |
| Sitar, DS | 1 |
| Graham, DN | 1 |
| Rangno, RE | 1 |
| Dufresne, LR | 1 |
| Barre, PE | 1 |
| Dhingra, RC | 1 |
| Rosen, KM | 1 |
| Reidenberg, MM | 2 |
| Drayer, DE | 3 |
| Matusik, E | 1 |
| Nelson, LD | 1 |
| Briggs, WA | 3 |
| du Souich, P | 1 |
| Erill, S | 1 |
| Lowenthal, DT | 3 |
| Woosley, RL | 1 |
| Nies, AS | 1 |
| Schwartz, A | 1 |
| Nelson, HA | 1 |
| Shapiro, B | 1 |
| Kollmann, GJ | 1 |
| Heine, WI | 1 |
| Matusik, EJ | 1 |
| Stevenson, WG | 1 |
| Weiss, J | 1 |
| Braden, GL | 1 |
| Fitzgibbons, JP | 1 |
| Germain, MJ | 1 |
| Ledewitz, HM | 1 |
| Raehl, CL | 1 |
| Moorthy, AV | 1 |
| Beirne, GJ | 1 |
| Sica, DA | 1 |
| Yonce, C | 1 |
| Small, R | 1 |
| Cefali, E | 1 |
| Harford, A | 1 |
| Poynor, W | 1 |
22 other studies available for procainamide and Kidney Failure, Chronic
| Article | Year |
|---|---|
Resin hemoperfusion for severe N-acetylprocainamide toxicity in patients with renal failure.
Topics: Acecainide; Aged; Arrhythmias, Cardiac; Female; Hemoperfusion; Humans; Kidney Failure, Chronic; Male | 1984 |
Excretion of procainamide into bile and saliva in rats with chronic renal failure.
Topics: Acecainide; Animals; Bile; Kidney Failure, Chronic; Male; Procainamide; Rats; Rats, Inbred Strains; | 1982 |
[Procainamide in renal failure].
Topics: Adult; Female; Half-Life; Humans; Kidney Failure, Chronic; Kinetics; Male; Middle Aged; Procainamide | 1983 |
High-dose procainamide in chronic renal failure.
Topics: Adult; Humans; Kidney Failure, Chronic; Male; Procainamide; Tachycardia | 1983 |
[Procainamide-induced bleeding tendencies in hemodialysis patients (author's transl)].
Topics: Adult; Blood Platelet Disorders; Humans; Iatrogenic Disease; Kidney Failure, Chronic; Male; Middle A | 1982 |
N-Acetylprocainamide pharmacokinetics in functionally anephric patients before and after perturbation by hemodialysis.
Topics: Acecainide; Adult; Computers; Female; Humans; Kidney Failure, Chronic; Kinetics; Male; Middle Aged; | 1979 |
Procainamide-induced sinus node dysfunction in patients with chronic renal failure.
Topics: Acecainide; Aged; Angina Pectoris; Arrhythmia, Sinus; Arrhythmias, Cardiac; Bradycardia; Female; Hea | 1979 |
Procainamide acetylation and disposition in dialysis patients.
Topics: Acetylation; Administration, Oral; Adult; Aged; Arrhythmias, Cardiac; Biological Availability; Femal | 1979 |
Procainamide and the sinus node.
Topics: Aged; Arrhythmia, Sinus; Humans; Kidney Failure, Chronic; Lidocaine; Procainamide; Sinoatrial Node | 1979 |
Drug metabolism and active drug metabolites in renal failure.
Topics: Allopurinol; Biotransformation; Clofibrate; Dose-Response Relationship, Drug; Humans; Kidney Failure | 1977 |
Kinetics of procainamide and N-acetylprocainamide in renal failure.
Topics: Adult; Female; Half-Life; Humans; Kidney Failure, Chronic; Kinetics; Male; Metabolic Clearance Rate; | 1977 |
Metabolism of procainamide in patients with chronic heart failure, chronic respiratory failure and chronic renal failure.
Topics: Acetylation; Adult; Aged; Chronic Disease; Female; Half-Life; Heart Failure; Humans; Hydrolysis; Kid | 1978 |
Active drug metabolites and renal failure.
Topics: Acetylation; Biotransformation; Clofibrate; Humans; Kidney Failure, Chronic; Meperidine; Methyldopa; | 1977 |
Pharmacokinetics of propranolol, quinidine, procainamide and lidocaine in chronic renal disease.
Topics: Biotransformation; Dose-Response Relationship, Drug; Humans; Kidney; Kidney Failure, Chronic; Lidoca | 1977 |
Cumulation of N-acetylprocainamide, an active metabolite of procainamide, in patients with impaired renal function.
Topics: Acetylation; Aged; Arrhythmias, Cardiac; Humans; Kidney Failure, Chronic; Male; Middle Aged; Procain | 1977 |
Elimination of procainamide in end stage renal failure.
Topics: Acetylation; Female; Half-Life; Humans; Kidney Failure, Chronic; Male; Procainamide; Renal Dialysis; | 1975 |
Pitfalls in the application of digoxin determinations.
Topics: Administration, Oral; Aged; Biopharmaceutics; Calcium; Digoxin; Drug Interactions; Female; Heart Dis | 1975 |
N-Acetylprocainamide levels in patients with end-stage renal failure.
Topics: Acetylation; Half-Life; Humans; Kidney Failure, Chronic; Kinetics; Metabolic Clearance Rate; Procain | 1976 |
Torsades de pointes due to n-acetylprocainamide.
Topics: Acecainide; Aged; Female; Humans; Kidney Failure, Chronic; Procainamide; Renal Dialysis; Tachycardia | 1985 |
Hemoperfusion for treatment of N-acetylprocainamide intoxication.
Topics: Acecainide; Hemoperfusion; Humans; Kidney Failure, Chronic; Kinetics; Male; Middle Aged; Procainamid | 1986 |
Procainamide pharmacokinetics in patients on continuous ambulatory peritoneal dialysis.
Topics: Acecainide; Adult; Aged; Half-Life; Humans; Kidney Failure, Chronic; Kinetics; Male; Middle Aged; Pe | 1986 |
Pharmacokinetics of procainamide in continuous ambulatory peritoneal dialysis.
Topics: Acecainide; Adult; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Peritoneal Dialysis, | 1988 |