procainamide has been researched along with Chronic Disease in 25 studies
Procainamide: A class Ia antiarrhythmic drug that is structurally-related to PROCAINE.
procainamide : A benzamide that is 4-aminobenzamide substituted on the amide N by a 2-(diethylamino)ethyl group. It is a pharmaceutical antiarrhythmic agent used for the medical treatment of cardiac arrhythmias.
Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Seven patients with chronic or recurrent supraventricular tachyarrhythmias were selected for a trial of antazoline therapy because sinus rhythm or a controlled ventricular response could not be achieved with quinidine, procainamide, digitalis or propranolol." | 9.04 | Antazoline therapy of recurrent refractory supraventricular arrhythmias--a preliminary report. ( Downar, E; Waxman, MB, 1975) |
| "Twenty-eight anesthetized mongrel dogs were studied 2 to 74 months after experimental myocardial infarction in order to examine the effects of procainamide, lidocaine and acetylstrophanthidin on conduction within the infarcted region and the way such effects relate to changes in body surface potentials and antiarrhythmic efficacy." | 7.67 | Differential effects of procainamide, lidocaine and acetylstrophanthidin on body surface potentials and epicardial conduction in dogs with chronic myocardial infarction. ( Balke, CW; de Langen, CD; Hanich, RF; Kadish, AH; Levine, JH; Michelson, EL; Moore, EN; Spear, JF, 1988) |
| "The effects of a single intravenous infusion of 750 mg of procainamide was studied in 12 patients with symptomatic chronic recurrent ventricular tachycardia in whom arrhythmias could reproducibly be initiated and terminated by programmed electrical stimulation of the heart." | 7.66 | Procainamide in the induction and perpetuation of ventricular tachycardia in man. ( El-Sherif, N; Gomes, JA; Kang, PS, 1982) |
| "We compared the relationship between plasma levels of procainamide and suppression or prevention of various forms of ventricular arrhythmias in 18 patients, six of whom had premature ventricular complexes (PVCs) during acute myocardial infarction (AMI), six of whom had PVCs in the setting of stable chronic ischemic heart disease (CIHD), and six of whom had recurrent symptomatic ventricular tachycardia (VT) with chronic PVCs between episodes of VT." | 7.66 | Relationship between plasma levels of procainamide, suppression of premature ventricular complexes and prevention of recurrent ventricular tachycardia. ( Castellanos, A; Conde, CA; Cooper, D; Kessler, KM; Kiem, I; Myerburg, RJ; Pefkaros, KC, 1981) |
| "Fractional hydrolysis and acetylation of procainamide, acetylation of procainamide-derived p-aminobenzoic acid and plasma hydrolysis of procaine were studied in 20 patients with chronic heart failure (CHF), 20 patients with chronic respiratory insufficiency (CRI) and 20 patients with chronic renal failure (RF)." | 7.66 | Metabolism of procainamide in patients with chronic heart failure, chronic respiratory failure and chronic renal failure. ( du Souich, P; Erill, S, 1978) |
| "Procainamide was successful in 13 (39%) patients." | 6.66 | Comparative efficacy of oral sotalol and procainamide in patients with chronic ventricular arrhythmias: a multicenter study. ( Lidell, C; Rehnqvist, N; Rønnevik, PK; Sjögren, A; Yli-Uotila, RJ, 1985) |
| "Seven patients with chronic or recurrent supraventricular tachyarrhythmias were selected for a trial of antazoline therapy because sinus rhythm or a controlled ventricular response could not be achieved with quinidine, procainamide, digitalis or propranolol." | 5.04 | Antazoline therapy of recurrent refractory supraventricular arrhythmias--a preliminary report. ( Downar, E; Waxman, MB, 1975) |
| " The incidence of clinical torsade de pointes (TdP) associated with amiodarone has been reported to be low and the present study compared the proarrhythmic potential of amiodarone with that of a selective IKr channel blocker, sematilide, using a canine chronic atrioventrucular block model." | 3.71 | Comparison of the in vivo electrophysiological and proarrhythmic effects of amiodarone with those of a selective class III drug, sematilide, using a canine chronic atrioventricular block model. ( Hashimoto, K; Ishida, Y; Kugiyama, K; Satoh, Y; Sugiyama, A; Yoneyama, M; Yoshida, H, 2002) |
| "Twenty-eight anesthetized mongrel dogs were studied 2 to 74 months after experimental myocardial infarction in order to examine the effects of procainamide, lidocaine and acetylstrophanthidin on conduction within the infarcted region and the way such effects relate to changes in body surface potentials and antiarrhythmic efficacy." | 3.67 | Differential effects of procainamide, lidocaine and acetylstrophanthidin on body surface potentials and epicardial conduction in dogs with chronic myocardial infarction. ( Balke, CW; de Langen, CD; Hanich, RF; Kadish, AH; Levine, JH; Michelson, EL; Moore, EN; Spear, JF, 1988) |
| "The effects of a single intravenous infusion of 750 mg of procainamide was studied in 12 patients with symptomatic chronic recurrent ventricular tachycardia in whom arrhythmias could reproducibly be initiated and terminated by programmed electrical stimulation of the heart." | 3.66 | Procainamide in the induction and perpetuation of ventricular tachycardia in man. ( El-Sherif, N; Gomes, JA; Kang, PS, 1982) |
| "We compared the relationship between plasma levels of procainamide and suppression or prevention of various forms of ventricular arrhythmias in 18 patients, six of whom had premature ventricular complexes (PVCs) during acute myocardial infarction (AMI), six of whom had PVCs in the setting of stable chronic ischemic heart disease (CIHD), and six of whom had recurrent symptomatic ventricular tachycardia (VT) with chronic PVCs between episodes of VT." | 3.66 | Relationship between plasma levels of procainamide, suppression of premature ventricular complexes and prevention of recurrent ventricular tachycardia. ( Castellanos, A; Conde, CA; Cooper, D; Kessler, KM; Kiem, I; Myerburg, RJ; Pefkaros, KC, 1981) |
| "Fractional hydrolysis and acetylation of procainamide, acetylation of procainamide-derived p-aminobenzoic acid and plasma hydrolysis of procaine were studied in 20 patients with chronic heart failure (CHF), 20 patients with chronic respiratory insufficiency (CRI) and 20 patients with chronic renal failure (RF)." | 3.66 | Metabolism of procainamide in patients with chronic heart failure, chronic respiratory failure and chronic renal failure. ( du Souich, P; Erill, S, 1978) |
| "Procainamide was successful in 13 (39%) patients." | 2.66 | Comparative efficacy of oral sotalol and procainamide in patients with chronic ventricular arrhythmias: a multicenter study. ( Lidell, C; Rehnqvist, N; Rønnevik, PK; Sjögren, A; Yli-Uotila, RJ, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (72.00) | 18.7374 |
| 1990's | 6 (24.00) | 18.2507 |
| 2000's | 1 (4.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yoshida, H | 1 |
| Sugiyama, A | 1 |
| Satoh, Y | 1 |
| Ishida, Y | 1 |
| Yoneyama, M | 1 |
| Kugiyama, K | 1 |
| Hashimoto, K | 1 |
| Zipes, DP | 1 |
| Orgain, ES | 1 |
| Ferlic, RM | 1 |
| Sellers, RD | 1 |
| Lillehei, CW | 1 |
| Eliot, RS | 1 |
| Kang, PS | 1 |
| Gomes, JA | 1 |
| El-Sherif, N | 1 |
| Sonnhag, C | 1 |
| Michelson, EL | 2 |
| Spear, JF | 2 |
| Moore, EN | 2 |
| Myerburg, RJ | 1 |
| Kessler, KM | 1 |
| Kiem, I | 1 |
| Pefkaros, KC | 1 |
| Conde, CA | 1 |
| Cooper, D | 1 |
| Castellanos, A | 1 |
| Kulakowski, P | 1 |
| Bashir, Y | 1 |
| Heald, S | 1 |
| Paul, V | 1 |
| Anderson, MH | 1 |
| Gibson, S | 1 |
| Malik, M | 1 |
| Camm, AJ | 1 |
| Erdem, S | 1 |
| Freimer, ML | 1 |
| O'Dorisio, T | 1 |
| Mendell, JR | 1 |
| Hsieh, MH | 1 |
| Chen, SA | 1 |
| Wen, ZC | 1 |
| Tai, CT | 1 |
| Chiang, CE | 1 |
| Ding, YA | 1 |
| Chang, MS | 1 |
| Agius, MA | 1 |
| Zhu, S | 1 |
| Fairclough, RH | 1 |
| du Souich, P | 2 |
| Erill, S | 2 |
| Reddy, CP | 1 |
| Gettes, LS | 1 |
| Wolf, PS | 1 |
| Downar, E | 1 |
| Waxman, MB | 1 |
| Wellens, HJ | 1 |
| Grosu, AA | 1 |
| Shevchenko, NM | 1 |
| Schmidt, SB | 1 |
| de Langen, CD | 1 |
| Hanich, RF | 1 |
| Kadish, AH | 1 |
| Levine, JH | 1 |
| Balke, CW | 1 |
| Lidell, C | 1 |
| Rehnqvist, N | 1 |
| Sjögren, A | 1 |
| Yli-Uotila, RJ | 1 |
| Rønnevik, PK | 1 |
| Justin-Besançon, L | 1 |
| Lortat-Jacob, JL | 1 |
| Cornet, A | 1 |
| Grivaux, M | 1 |
| Blanc, L | 1 |
| Bousser, F | 1 |
| Pavel, I | 1 |
| Pieptea, R | 1 |
| Percek, A | 1 |
| Ulmeanu, D | 1 |
| Dimich, I | 1 |
| Steinfeld, L | 1 |
| Richman, R | 1 |
| Lasser, R | 1 |
| Mertens, HG | 1 |
| Lützenkirchen, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Non-invasive Programmed Stimulation to Identify High-risk Patients With Implanted Cardioverter-defibrillator[NCT02373306] | 150 participants (Anticipated) | Interventional | 2013-11-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for procainamide and Chronic Disease
| Article | Year |
|---|---|
Effects of antiarrhythmic drugs on variability of ventricular rate and exercise performance in chronic atrial fibrillation complicated with ventricular arrhythmias.
Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Blood Pressure; Chi-Square | 1998 |
Antazoline therapy of recurrent refractory supraventricular arrhythmias--a preliminary report.
Topics: Adolescent; Adult; Aged; Antazoline; Arrhythmias, Cardiac; Chronic Disease; Clinical Trials as Topic | 1975 |
Comparative efficacy of oral sotalol and procainamide in patients with chronic ventricular arrhythmias: a multicenter study.
Topics: Adult; Aged; Arrhythmias, Cardiac; Chronic Disease; Clinical Trials as Topic; Dose-Response Relation | 1985 |
22 other studies available for procainamide and Chronic Disease
| Article | Year |
|---|---|
Comparison of the in vivo electrophysiological and proarrhythmic effects of amiodarone with those of a selective class III drug, sematilide, using a canine chronic atrioventricular block model.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chronic Disease; Dogs; Dose-Respo | 2002 |
Refractory paroxysmal ventricular tachycardia.
Topics: Atrial Fibrillation; Chronic Disease; Digoxin; Electrocardiography; Heart Ventricles; Humans; Hydroc | 1967 |
Cardioversion as an adjunct to cardiac surgery.
Topics: Adult; Anticoagulants; Atrial Fibrillation; Atrial Flutter; Cardiac Surgical Procedures; Chronic Dis | 1967 |
Procainamide in the induction and perpetuation of ventricular tachycardia in man.
Topics: Aged; Cardiac Pacing, Artificial; Cardiomyopathies; Chronic Disease; Coronary Disease; Dose-Response | 1982 |
Efficacy and tolerance of tocainide during acute and long-term treatment of chronic ventricular arrhythmias.
Topics: Adult; Aged; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chronic Disease; Electrocardiog | 1980 |
Effects of procainamide on strength-interval relations in normal and chronically infarcted canine myocardium.
Topics: Animals; Anti-Arrhythmia Agents; Chronic Disease; Dogs; Electrophysiology; Heart; Myocardial Infarct | 1981 |
Relationship between plasma levels of procainamide, suppression of premature ventricular complexes and prevention of recurrent ventricular tachycardia.
Topics: Acute Disease; Aged; Chronic Disease; Coronary Disease; Dose-Response Relationship, Drug; Electrocar | 1981 |
Effects of procainamide on the signal-averaged electrocardiogram in relation to the results of programmed ventricular stimulation in patients with sustained monomorphic ventricular tachycardia.
Topics: Aged; Cardiac Pacing, Artificial; Chronic Disease; Electrocardiography; Humans; Male; Middle Aged; P | 1993 |
Procainamide-induced chronic inflammatory demyelinating polyradiculoneuropathy.
Topics: Aged; Anti-Arrhythmia Agents; Chronic Disease; Demyelinating Diseases; Humans; Male; Neural Conducti | 1998 |
Antirapsyn antibodies in chronic procainamide-associated myopathy (CPAM).
Topics: Aged; Aged, 80 and over; Animals; Autoantibodies; Chronic Disease; Electric Organ; Enzyme-Linked Imm | 1998 |
Metabolism of procainamide and p-aminobenzoic acid in patients with chronic liver disease.
Topics: 4-Aminobenzoic Acid; Acetylation; Adult; Aged; Aminobenzoates; Chronic Disease; Female; Half-Life; H | 1977 |
Use of isoproterenol as an aid to electric induction of chronic recurrent ventricular tachycardia.
Topics: Adolescent; Adult; Aged; Chronic Disease; Electric Stimulation; Exercise Test; Female; Heart Rate; H | 1979 |
Arrhythmias in chronic pulmonary disease.
Topics: Arrhythmias, Cardiac; Chronic Disease; Digoxin; Humans; Hypokalemia; Hypoxia; Lidocaine; Lung Diseas | 1979 |
Metabolism of procainamide in patients with chronic heart failure, chronic respiratory failure and chronic renal failure.
Topics: Acetylation; Adult; Aged; Chronic Disease; Female; Half-Life; Heart Failure; Humans; Hydrolysis; Kid | 1978 |
Pathophysiology of ventricular tachycardia in man.
Topics: Chronic Disease; Electric Stimulation; Electrocardiography; Heart Ventricles; Humans; Myocardial Inf | 1975 |
[The potentials for curing atrial flutter by the combined use of transesophageal electrical stimulation and anti-arrhythmia preparations].
Topics: Adult; Aged; Anti-Arrhythmia Agents; Atrial Flutter; Cardiac Pacing, Artificial; Chronic Disease; Co | 1990 |
Survey of physician practices in managing patients with chronic ventricular arrhythmias.
Topics: Arrhythmias, Cardiac; Chronic Disease; Humans; Practice Patterns, Physicians'; Procainamide; Quinidi | 1990 |
Differential effects of procainamide, lidocaine and acetylstrophanthidin on body surface potentials and epicardial conduction in dogs with chronic myocardial infarction.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chronic Disease; Dogs; Electrocardiography; E | 1988 |
[Chronic digestive disorders of vagotomized patients].
Topics: Adult; Aged; Chronic Disease; Deglutition Disorders; Digestive System; Dyspepsia; Female; Gastroente | 1967 |
[Apropos of the functional origin of certain types of chronic jaundice].
Topics: Adult; Chronic Disease; Hepatomegaly; Humans; Hyperbilirubinemia; Jaundice; Male; Procainamide; Sple | 1967 |
Treatment of recurrent paroxysmal ventricular tachycardia.
Topics: Child; Chronic Disease; Electrocardiography; Humans; Male; Phenytoin; Procainamide; Propranolol; Tac | 1970 |
[Neuropsychotropic drugs in the treatment of so-called pain syndromes].
Topics: Aminobutyrates; Benperidol; Chronic Disease; Diazepam; Humans; Hydantoins; Neuralgia; Pain; Procaina | 1970 |