procainamide has been researched along with Chemical and Drug Induced Liver Injury in 12 studies
Procainamide: A class Ia antiarrhythmic drug that is structurally-related to PROCAINE.
procainamide : A benzamide that is 4-aminobenzamide substituted on the amide N by a 2-(diethylamino)ethyl group. It is a pharmaceutical antiarrhythmic agent used for the medical treatment of cardiac arrhythmias.
Chemical and Drug Induced Liver Injury: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Trovafloxacin (Trovan) is a fluoroquinolone antibiotic drug with a long half-life and broad-spectrum activity." | 1.35 | In vitro metabolism of a model cyclopropylamine to reactive intermediate: insights into trovafloxacin-induced hepatotoxicity. ( Foss, FW; Macdonald, TL; Sun, Q; Zhu, R, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (41.67) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 5 (41.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fourches, D | 1 |
| Barnes, JC | 1 |
| Day, NC | 1 |
| Bradley, P | 1 |
| Reed, JZ | 1 |
| Tropsha, A | 1 |
| Morgan, RE | 2 |
| Trauner, M | 1 |
| van Staden, CJ | 2 |
| Lee, PH | 1 |
| Ramachandran, B | 1 |
| Eschenberg, M | 1 |
| Afshari, CA | 2 |
| Qualls, CW | 1 |
| Lightfoot-Dunn, R | 1 |
| Hamadeh, HK | 2 |
| Liu, Z | 1 |
| Shi, Q | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Fang, H | 1 |
| Tong, W | 2 |
| Chen, Y | 1 |
| Kalyanaraman, N | 1 |
| Kalanzi, J | 1 |
| Dunn, RT | 1 |
| Chen, M | 1 |
| Suzuki, A | 1 |
| Thakkar, S | 1 |
| Yu, K | 1 |
| Hu, C | 1 |
| Sun, Q | 1 |
| Zhu, R | 1 |
| Foss, FW | 1 |
| Macdonald, TL | 1 |
| Rotmensch, HH | 2 |
| Weintraub, M | 1 |
| Sofferman, G | 1 |
| Livni, E | 1 |
| Klejman, A | 1 |
| Liron, M | 2 |
| Yung, R | 1 |
| Williams, R | 1 |
| Johnson, K | 1 |
| Phillips, C | 1 |
| Stoolman, L | 1 |
| Chang, S | 1 |
| Richardson, B | 1 |
| Drayer, DE | 1 |
| Reidenberg, MM | 1 |
| Yust, I | 1 |
| Siegman-Igra, Y | 1 |
| Ilie, B | 1 |
| Vardinon, N | 1 |
| Reuning, RH | 1 |
| Schanker, LS | 1 |
| Farber, HI | 1 |
1 review available for procainamide and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr | 2016 |
11 other studies available for procainamide and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters | 2010 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily | 2013 |
In vitro metabolism of a model cyclopropylamine to reactive intermediate: insights into trovafloxacin-induced hepatotoxicity.
Topics: Aldehydes; Anti-Bacterial Agents; Chemical and Drug Induced Liver Injury; Cross-Linking Reagents; Cy | 2008 |
Experience with immunological tests in drug-induced hepatitis.
Topics: Aged; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Female; Fluorescent Antibody Te | 1981 |
Mechanisms of drug-induced lupus. III. Sex-specific differences in T cell homing may explain increased disease severity in female mice.
Topics: Adoptive Transfer; Animals; Antibodies, Antinuclear; Autoantibodies; Autoimmune Diseases; Chemical a | 1997 |
Clinical consequences of polymorphic acetylation of basic drugs.
Topics: Acetylation; Antibodies, Antinuclear; Biotransformation; Chemical and Drug Induced Liver Injury; Hum | 1977 |
Granulomatous hepatitis: a hypersensitivity response to procainamide.
Topics: Acute Disease; Administration, Oral; Aged; Biopsy; Chemical and Drug Induced Liver Injury; Drug Hype | 1978 |
Effect of carbon tetrachloride-induced liver damage on organic ion transport in rat liver.
Topics: Aminohippuric Acids; Animals; Bile; Biological Transport, Active; Carbon Tetrachloride Poisoning; Ch | 1972 |
Fever, vomiting, and liver dysfunction with procainamide therapy.
Topics: Ampicillin; Blood; Chemical and Drug Induced Liver Injury; Digitalis; Drug Hypersensitivity; Female; | 1974 |