Page last updated: 2024-11-03

procainamide and Cardiac Arrest, Sudden

procainamide has been researched along with Cardiac Arrest, Sudden in 12 studies

Procainamide: A class Ia antiarrhythmic drug that is structurally-related to PROCAINE.
procainamide : A benzamide that is 4-aminobenzamide substituted on the amide N by a 2-(diethylamino)ethyl group. It is a pharmaceutical antiarrhythmic agent used for the medical treatment of cardiac arrhythmias.

Research Excerpts

ExcerptRelevanceReference
" This case report highlights a patient who developed drug-induced Brugada type I pattern after a procainamide infusion for the treatment of new-onset atrial fibrillation (AF) or flutter and discusses the implications for this incidental but potentially lethal finding."8.31Procainamide-Provoked Brugada Pattern in a Patient Presenting with New-Onset Atrial Fibrillation or Flutter: When Does it Matter? ( Balasubramanian, S; Freedman, Z; Katz, A, 2023)
"Brugada syndrome is a clinical and electrocardiographic entity characterized by ST segment elevation in the right precordial ECG leads and sudden death or syncope secondary to malignant ventricular arrhythmia, and has a high recurrence rate."5.32[Recurrent ventricular fibrillation in a patient with Brugada syndrome successfully treated with procainamide]. ( Merino, JL; Peinado, A; Peinado, R; Sánchez-Aquino, RM; Sobrino, JA, 2003)
" This case report highlights a patient who developed drug-induced Brugada type I pattern after a procainamide infusion for the treatment of new-onset atrial fibrillation (AF) or flutter and discusses the implications for this incidental but potentially lethal finding."4.31Procainamide-Provoked Brugada Pattern in a Patient Presenting with New-Onset Atrial Fibrillation or Flutter: When Does it Matter? ( Balasubramanian, S; Freedman, Z; Katz, A, 2023)
"A Brugada syndrome locus distinct from SCN5A is associated with progressive conduction disease, a low sensitivity to procainamide testing, and a relatively good prognosis in a single large pedigree."3.71Clinical and molecular heterogeneity in the Brugada syndrome: a novel gene locus on chromosome 3. ( Angelilli, A; Barmada, MM; Cavlovich, D; Kornblit, CA; London, B; McNamara, DM; Nguyen, T; Seibel, JS; Villanueva, F; Weiss, R, 2002)
"Unexplained cardiac arrest (UCA) may be explained by inherited arrhythmia syndromes."1.43Cardiac Abnormalities in First-Degree Relatives of Unexplained Cardiac Arrest Victims: A Report From the Cardiac Arrest Survivors With Preserved Ejection Fraction Registry. ( Andrade, JG; Angaran, P; Birnie, DH; Champagne, J; Chauhan, VS; Gardner, M; Gerull, B; Healey, JS; Janzen, M; Klein, GJ; Krahn, AD; Leather, R; Padfield, GJ; Roberts, JD; Sanatani, S; Seifer, C; Simpson, CS; Steinberg, C; Talajic, M, 2016)
"Brugada syndrome is a clinical and electrocardiographic entity characterized by ST segment elevation in the right precordial ECG leads and sudden death or syncope secondary to malignant ventricular arrhythmia, and has a high recurrence rate."1.32[Recurrent ventricular fibrillation in a patient with Brugada syndrome successfully treated with procainamide]. ( Merino, JL; Peinado, A; Peinado, R; Sánchez-Aquino, RM; Sobrino, JA, 2003)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (25.00)18.2507
2000's6 (50.00)29.6817
2010's2 (16.67)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Katz, A1
Balasubramanian, S1
Freedman, Z1
Steinberg, C1
Padfield, GJ1
Champagne, J1
Sanatani, S1
Angaran, P1
Andrade, JG1
Roberts, JD1
Healey, JS1
Chauhan, VS1
Birnie, DH1
Janzen, M1
Gerull, B1
Klein, GJ1
Leather, R1
Simpson, CS1
Seifer, C1
Talajic, M1
Gardner, M1
Krahn, AD1
Behr, ER1
Camm, AJ1
De Rosa, F1
Mancuso, P1
Chiatto, M1
Calvelli, A1
De Donato, V1
Mazza, S1
Spadafora, G1
Sánchez-Aquino, RM1
Peinado, R1
Peinado, A1
Merino, JL1
Sobrino, JA1
Junttila, MJ1
Gonzalez, M1
Lizotte, E1
Benito, B1
Vernooy, K1
Sarkozy, A1
Huikuri, HV1
Brugada, P1
Brugada, J1
Brugada, R1
Mélon, P1
Waleffe, A1
Kulbertus, H1
Humphries, JO1
Chen, SM1
Kuo, CT1
Lin, KH1
Chiang, FT1
Sangwatanaroj, S1
Prechawat, S1
Sunsaneewitayakul, B1
Sitthisook, S1
Tosukhowong, P1
Tungsanga, K1
Weiss, R1
Barmada, MM1
Nguyen, T1
Seibel, JS1
Cavlovich, D1
Kornblit, CA1
Angelilli, A1
Villanueva, F1
McNamara, DM1
London, B1
Hallstrom, AP1
Cobb, LA1
Yu, BH1
Weaver, WD1
Fahrenbruch, CE1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Cardiac Arrest Survivors With Preserved Ejection Fraction Registry (CASPER)[NCT00292032]1,529 participants (Actual)Observational2004-05-31Completed
Detection of Electrocardiographic Brugada Patterns Using High Precordial Leads Positioning Among Asymptomatic Upper Egyptian Population[NCT05116488]300 participants (Anticipated)Observational2021-12-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for procainamide and Cardiac Arrest, Sudden

ArticleYear
[Ventricular preexcitation: is risk stratification feasible?].
    Giornale italiano di cardiologia (2006), 2010, Volume: 11, Issue:4

    Topics: Adolescent; Adult; Age Distribution; Ajmaline; Atrioventricular Node; Catheter Ablation; Child; Chil

2010
Induced Brugada-type electrocardiogram, a sign for imminent malignant arrhythmias.
    Circulation, 2008, Apr-08, Volume: 117, Issue:14

    Topics: Adult; Age of Onset; Anesthetics; Antidepressive Agents, Tricyclic; Brugada Syndrome; Cocaine; Death

2008
Unexpected instant death following successful coronary artery bypass graft surgery (and other clinical settings): atrial fibrillation, quinidine, procainamide, et cetera, and instant death.
    Clinical cardiology, 1998, Volume: 21, Issue:10

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Clinical Trials as Topic; Coronary Artery B

1998

Other Studies

9 other studies available for procainamide and Cardiac Arrest, Sudden

ArticleYear
Procainamide-Provoked Brugada Pattern in a Patient Presenting with New-Onset Atrial Fibrillation or Flutter: When Does it Matter?
    The Journal of emergency medicine, 2023, Volume: 65, Issue:3

    Topics: Atrial Fibrillation; Brugada Syndrome; China; Death, Sudden, Cardiac; Electrocardiography; Humans; M

2023
Cardiac Abnormalities in First-Degree Relatives of Unexplained Cardiac Arrest Victims: A Report From the Cardiac Arrest Survivors With Preserved Ejection Fraction Registry.
    Circulation. Arrhythmia and electrophysiology, 2016, Volume: 9, Issue:9

    Topics: Adult; Anti-Arrhythmia Agents; Canada; Death, Sudden, Cardiac; Diagnostic Imaging; Electrocardiograp

2016
Letter by Behr and Camm regarding article, "Induced Brugada-type electrocardiogram, a sign for imminent malignant arrhythmias".
    Circulation, 2008, Nov-18, Volume: 118, Issue:21

    Topics: Adult; Age of Onset; Anesthetics; Antidepressive Agents, Tricyclic; Brugada Syndrome; Cocaine; Death

2008
[Recurrent ventricular fibrillation in a patient with Brugada syndrome successfully treated with procainamide].
    Revista espanola de cardiologia, 2003, Volume: 56, Issue:11

    Topics: Anti-Arrhythmia Agents; Bundle-Branch Block; Death, Sudden, Cardiac; Defibrillators, Implantable; El

2003
[Wolff-Parkinson-White syndrome accompanying rapid conduction atrial fibrillation].
    Revue medicale de Liege, 1997, Volume: 52, Issue:11

    Topics: Adult; Anti-Arrhythmia Agents; Atrial Fibrillation; Catheter Ablation; Death, Sudden, Cardiac; Elect

1997
Brugada syndrome without mutation of the cardiac sodium channel gene in a Taiwanese patient.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2000, Volume: 99, Issue:11

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac;

2000
New electrocardiographic leads and the procainamide test for the detection of the Brugada sign in sudden unexplained death syndrome survivors and their relatives.
    European heart journal, 2001, Volume: 22, Issue:24

    Topics: Anti-Arrhythmia Agents; Asian People; Bundle-Branch Block; Death, Sudden, Cardiac; Electrocardiograp

2001
Clinical and molecular heterogeneity in the Brugada syndrome: a novel gene locus on chromosome 3.
    Circulation, 2002, Feb-12, Volume: 105, Issue:6

    Topics: Adult; Age Factors; Aged; Bundle-Branch Block; Chromosomes, Human, Pair 3; Comorbidity; Death, Sudde

2002
An antiarrhythmic drug experience in 941 patients resuscitated from an initial cardiac arrest between 1970 and 1985.
    The American journal of cardiology, 1991, Oct-15, Volume: 68, Issue:10

    Topics: Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Death, Sudden, Cardiac; Heart Arrest; Humans;

1991