procainamide has been researched along with Cancer of Prostate in 2 studies
Procainamide: A class Ia antiarrhythmic drug that is structurally-related to PROCAINE.
procainamide : A benzamide that is 4-aminobenzamide substituted on the amide N by a 2-(diethylamino)ethyl group. It is a pharmaceutical antiarrhythmic agent used for the medical treatment of cardiac arrhythmias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Human prostate cancer (PCA) cells characteristically contain hypermethylated CpG island sequences encompassing the transcriptional regulatory region of GSTP1, the gene encoding the pi-class glutathione S-transferase (GSTP1), and fail to express GSTP1 as a consequence of transcriptional "silencing." | 1.31 | Reversal of GSTP1 CpG island hypermethylation and reactivation of pi-class glutathione S-transferase (GSTP1) expression in human prostate cancer cells by treatment with procainamide. ( Asgari, K; Cornblatt, BS; De Marzo, AM; DeWeese, TL; Gage, WR; Kumar, A; Lin, X; Nelson, WG; Piantadosi, S; Putzi, MJ; Yu, X, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chuang, JC | 1 |
| Yoo, CB | 1 |
| Kwan, JM | 1 |
| Li, TW | 1 |
| Liang, G | 1 |
| Yang, AS | 1 |
| Jones, PA | 1 |
| Lin, X | 1 |
| Asgari, K | 1 |
| Putzi, MJ | 1 |
| Gage, WR | 1 |
| Yu, X | 1 |
| Cornblatt, BS | 1 |
| Kumar, A | 1 |
| Piantadosi, S | 1 |
| DeWeese, TL | 1 |
| De Marzo, AM | 1 |
| Nelson, WG | 1 |
2 other studies available for procainamide and Cancer of Prostate
| Article | Year |
|---|---|
Comparison of biological effects of non-nucleoside DNA methylation inhibitors versus 5-aza-2'-deoxycytidine.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Transitional Cell; Catechin; Cell Line, Tum | 2005 |
Reversal of GSTP1 CpG island hypermethylation and reactivation of pi-class glutathione S-transferase (GSTP1) expression in human prostate cancer cells by treatment with procainamide.
Topics: Animals; CpG Islands; DNA Methylation; DNA Modification Methylases; Enzyme Activation; Enzyme Inhibi | 2001 |