Page last updated: 2024-11-03

procainamide and Brugada ECG Pattern

procainamide has been researched along with Brugada ECG Pattern in 34 studies

Procainamide: A class Ia antiarrhythmic drug that is structurally-related to PROCAINE.
procainamide : A benzamide that is 4-aminobenzamide substituted on the amide N by a 2-(diethylamino)ethyl group. It is a pharmaceutical antiarrhythmic agent used for the medical treatment of cardiac arrhythmias.

Research Excerpts

ExcerptRelevanceReference
" This case report highlights a patient who developed drug-induced Brugada type I pattern after a procainamide infusion for the treatment of new-onset atrial fibrillation (AF) or flutter and discusses the implications for this incidental but potentially lethal finding."8.31Procainamide-Provoked Brugada Pattern in a Patient Presenting with New-Onset Atrial Fibrillation or Flutter: When Does it Matter? ( Balasubramanian, S; Freedman, Z; Katz, A, 2023)
"This study aimed to investigate the predictive value of T-peak to T-end interval and corrected T-peak to T-end interval for predicting the positive response of the ajmaline challenge test in suspected Brugada syndrome patients."8.12T-Peak to T-End Interval for Prediction of Positive Response to Ajmaline Challenge Test in Suspected Brugada Syndrome Patients. ( Chokesuwattanaskul, R; Leelapatana, P; Prechawat, S; Rungpradubvong, V; Thapanasuta, M, 2022)
" This case report highlights a patient who developed drug-induced Brugada type I pattern after a procainamide infusion for the treatment of new-onset atrial fibrillation (AF) or flutter and discusses the implications for this incidental but potentially lethal finding."4.31Procainamide-Provoked Brugada Pattern in a Patient Presenting with New-Onset Atrial Fibrillation or Flutter: When Does it Matter? ( Balasubramanian, S; Freedman, Z; Katz, A, 2023)
" When DL was applied to consecutive 10-second, clean ECGs from 24-hour 12-lead Holters, spontaneous Brugada type 1 was detected in 48% of patients with procainamide-induced Brugada syndrome and in 33% with suspected Brugada syndrome."4.12Use of Wearable Technology and Deep Learning to Improve the Diagnosis of Brugada Syndrome. ( Bokhari, M; Chakraborty, P; Chauhan, VS; Gollob, M; Jones, G; Liao, S; Spears, D; Suszko, A; Wang, B; Zhang, Z, 2022)
"This study aimed to investigate the predictive value of T-peak to T-end interval and corrected T-peak to T-end interval for predicting the positive response of the ajmaline challenge test in suspected Brugada syndrome patients."4.12T-Peak to T-End Interval for Prediction of Positive Response to Ajmaline Challenge Test in Suspected Brugada Syndrome Patients. ( Chokesuwattanaskul, R; Leelapatana, P; Prechawat, S; Rungpradubvong, V; Thapanasuta, M, 2022)
"Irrespective of the baseline ECG, procainamide testing provoked a Brugada pattern in a significant proportion of subjects with UCA or a FHSD, thereby facilitating a diagnosis of Brugada syndrome, and is recommended in the workup of UCA."3.80Procainamide infusion in the evaluation of unexplained cardiac arrest: from the Cardiac Arrest Survivors with Preserved Ejection Fraction Registry (CASPER). ( Angaran, P; Birnie, DH; Chakrabarti, S; Champagne, J; Chauhan, VS; Gardner, M; Gerull, B; Gollob, MH; Gow, RM; Gula, LJ; Healey, JS; Klein, GJ; Krahn, AD; Leong-Sit, P; Sanatani, S; Simpson, CS; Skanes, AC; Somani, R; Talajic, M; Yee, R, 2014)
"Procainamide is known to prolong PR, QRS, and QTc intervals in adults and is utilized to unmask the distinct electrocardiographic signatures, including right bundle branch block pattern and right precordial ST segment elevation seen with Brugada syndrome."3.80Universal ECG changes in pediatric patients undergoing procainamide challenge. ( Berul, CI; Greene, EA; Jordan, CP; Moak, JP, 2014)
"Procainamide is a sodium channel blocker used to diagnose BrS."1.62The clinical utility of procainamide-induced late potentials on the signal averaged ECG. ( Alqarawi, W; Krahn, AD; Laksman, Z; Larsen, JM; Leach, E; Pearman, CM; Walia, J, 2021)
"The Brugada syndrome is a heterogeneous genetic disease that predisposes to life-threatening ventricular tachyarrhythmias and sudden cardiac death (SCD)."1.39Positive Brugada challenge test in V1 R-V3 R as a predictor of malignant prognosis in Brugada patients. ( Aslani, A; Emkanjoo, Z; Hashemi, A; Saber, S; Shahrzad, S; Taban, S, 2013)
"The ECG features of Brugada syndrome are dynamic and frequently concealed."1.36Sensitivity and specificity of sodium channel blocking test in the diagnosis of Brugada syndrome. ( Efremidis, M; Gavrielatos, G; Kardaras, F; Letsas, KP; Pappas, LK; Sideris, A, 2010)
" Log dose-response curves were plotted for quinidine, papaverine, procaine, dibenamine and procaine amide."1.24A comparison of tests for antifibrillatory action. ( SZEKERES, L; WILLIAMS, EM, 1961)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199019 (55.88)18.7374
1990's0 (0.00)18.2507
2000's4 (11.76)29.6817
2010's7 (20.59)24.3611
2020's4 (11.76)2.80

Authors

AuthorsStudies
Pearman, CM1
Walia, J1
Alqarawi, W1
Larsen, JM1
Leach, E1
Krahn, AD3
Laksman, Z1
Liao, S1
Bokhari, M1
Chakraborty, P1
Suszko, A1
Jones, G1
Spears, D1
Gollob, M1
Zhang, Z1
Wang, B1
Chauhan, VS3
Thapanasuta, M1
Chokesuwattanaskul, R1
Leelapatana, P1
Rungpradubvong, V1
Prechawat, S1
Katz, A1
Balasubramanian, S1
Freedman, Z1
Cheung, CC1
Mellor, G1
Deyell, MW1
Ensam, B1
Batchvarov, V1
Papadakis, M1
Roberts, JD1
Leather, R1
Sanatani, S2
Healey, JS2
Birnie, DH2
Champagne, J2
Angaran, P2
Klein, GJ2
Yee, R2
Simpson, CS2
Talajic, M2
Gardner, M2
Yeung-Lai-Wah, JA1
Chakrabarti, S2
Laksman, ZW1
Sharma, S1
Behr, ER2
Sun, AY1
Hashemi, A1
Shahrzad, S2
Saber, S1
Taban, S1
Aslani, A1
Emkanjoo, Z1
Somani, R1
Gow, RM1
Gerull, B1
Skanes, AC1
Gula, LJ1
Leong-Sit, P1
Gollob, MH1
Jordan, CP1
Berul, CI1
Moak, JP1
Greene, EA1
Camm, AJ1
Gavrielatos, G1
Letsas, KP1
Pappas, LK1
Efremidis, M1
Sideris, A1
Kardaras, F1
Reiffel, JA1
ZURN, L1
KLOPPE, W1
CONTI, A1
DANESE, C1
HAEGER, K2
JOHANSSON, B2
SJOSTROM, B2
VOIT, K1
SECKFORT, H1
EICHLER, O1
CATINAT, J1
CASASSUS, P1
LIPOVETSKII, BM1
ROZIN, MZ1
WILLIAMS, EM1
SZEKERES, L1
KEMPEN, RR1
VAN HORN, G1
TERNOVA, TI1
BRANCADORO, G1
URSINI, M1
WINBURY, MM1
HEMMER, ML1
SANABRIA, A1
CARBONELL, LM1
SOTO, R1
MORRIS, LE1
HAID, B1
McCORD, MC1
TAGUCHI, JT1
BERRY, K1
GARLETT, EL1
BELLET, S1
GEFTER, WI1
MARTELLI, A1
COMISIONERU, N1
Joshi, S1
Raiszadeh, F1
Pierce, W1
Steinberg, JS1
Otten, RF1
Dusa, AC1
Das, MK1
Junttila, MJ1
Gonzalez, M1
Lizotte, E1
Benito, B1
Vernooy, K1
Sarkozy, A1
Huikuri, HV1
Brugada, P1
Brugada, J1
Brugada, R1

Reviews

1 review available for procainamide and Brugada ECG Pattern

ArticleYear
Induced Brugada-type electrocardiogram, a sign for imminent malignant arrhythmias.
    Circulation, 2008, Apr-08, Volume: 117, Issue:14

    Topics: Adult; Age of Onset; Anesthetics; Antidepressive Agents, Tricyclic; Brugada Syndrome; Cocaine; Death

2008

Other Studies

33 other studies available for procainamide and Brugada ECG Pattern

ArticleYear
The clinical utility of procainamide-induced late potentials on the signal averaged ECG.
    Pacing and clinical electrophysiology : PACE, 2021, Volume: 44, Issue:12

    Topics: Adult; Brugada Syndrome; Electrocardiography; Female; Humans; Male; Middle Aged; Procainamide; Volta

2021
Use of Wearable Technology and Deep Learning to Improve the Diagnosis of Brugada Syndrome.
    JACC. Clinical electrophysiology, 2022, Volume: 8, Issue:8

    Topics: Brugada Syndrome; Deep Learning; Electrocardiography; Humans; Procainamide; Wearable Electronic Devi

2022
T-Peak to T-End Interval for Prediction of Positive Response to Ajmaline Challenge Test in Suspected Brugada Syndrome Patients.
    Medical sciences (Basel, Switzerland), 2022, 12-19, Volume: 10, Issue:4

    Topics: Ajmaline; Brugada Syndrome; Flecainide; Humans; Procainamide; Sodium Channel Blockers

2022
Procainamide-Provoked Brugada Pattern in a Patient Presenting with New-Onset Atrial Fibrillation or Flutter: When Does it Matter?
    The Journal of emergency medicine, 2023, Volume: 65, Issue:3

    Topics: Atrial Fibrillation; Brugada Syndrome; China; Death, Sudden, Cardiac; Electrocardiography; Humans; M

2023
Comparison of Ajmaline and Procainamide Provocation Tests in the Diagnosis of Brugada Syndrome.
    JACC. Clinical electrophysiology, 2019, Volume: 5, Issue:4

    Topics: Adult; Ajmaline; Brugada Syndrome; Cohort Studies; Electrocardiography; Female; Humans; Male; Middle

2019
Drug Provocation Testing in Brugada Syndrome: A Test of Uncertain Significance.
    JACC. Clinical electrophysiology, 2019, Volume: 5, Issue:4

    Topics: Ajmaline; Anti-Arrhythmia Agents; Brugada Syndrome; Humans; NAV1.5 Voltage-Gated Sodium Channel; Pro

2019
Positive Brugada challenge test in V1 R-V3 R as a predictor of malignant prognosis in Brugada patients.
    Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2013, Volume: 18, Issue:5

    Topics: Adolescent; Adult; Anti-Arrhythmia Agents; Brugada Syndrome; Electrocardiography; Female; Flecainide

2013
Procainamide infusion in the evaluation of unexplained cardiac arrest: from the Cardiac Arrest Survivors with Preserved Ejection Fraction Registry (CASPER).
    Heart rhythm, 2014, Volume: 11, Issue:6

    Topics: Adolescent; Adult; Aged; Brugada Syndrome; Female; Heart Arrest; Humans; Male; Middle Aged; Procaina

2014
Universal ECG changes in pediatric patients undergoing procainamide challenge.
    Pacing and clinical electrophysiology : PACE, 2014, Volume: 37, Issue:9

    Topics: Brugada Syndrome; Child; Diagnosis, Differential; Electrocardiography; Female; Humans; Male; Procain

2014
Letter by Behr and Camm regarding article, "Induced Brugada-type electrocardiogram, a sign for imminent malignant arrhythmias".
    Circulation, 2008, Nov-18, Volume: 118, Issue:21

    Topics: Adult; Age of Onset; Anesthetics; Antidepressive Agents, Tricyclic; Brugada Syndrome; Cocaine; Death

2008
Sensitivity and specificity of sodium channel blocking test in the diagnosis of Brugada syndrome.
    International journal of cardiology, 2010, May-28, Volume: 141, Issue:2

    Topics: Aged; Anti-Arrhythmia Agents; Brugada Syndrome; Echocardiography; Electrocardiography; Humans; Male;

2010
Does a Brugada pattern ECG precipitated by excessive-dose flecainide provide a diagnosis of a Brugada syndrome patient and/or contraindicate its use? A case study.
    Circulation. Arrhythmia and electrophysiology, 2011, Volume: 4, Issue:4

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Brugada Syndrome; Catheter Ablation; Contraindications;

2011
[Autonomic block with novocaine and novocaine amide; prevention and therapy of cardiac arrhythmia during narcosis].
    Thoraxchirurgie, 1953, Volume: 1, Issue:3

    Topics: Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Heart Conduction System;

1953
[Auricular flutter and fibrillation and their response to novocamide].
    Arztliche Wochenschrift, 1954, Feb-26, Volume: 9, Issue:9

    Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Brugada Syndrome; Cardiac Conduction Syst

1954
[Procaine amide therapy of postoperative cardiac arrhythmia].
    Minerva medica, 1954, Feb-28, Volume: 45, Issue:17

    Topics: Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Electrocardiography; Hear

1954
Electrocardiographic studies on fibrillating and nonfibrillating hypothermic dogs with or without previous treatment with acetylcholine or procaine amide.
    American heart journal, 1957, Volume: 53, Issue:1

    Topics: Acetylcholine; Animals; Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; D

1957
Electrocardiographic studies on fibrillating and nonfibrillating hypothermic dogs with or without previous treatment with acetylcholine or procaine amide.
    American heart journal, 1957, Volume: 53, Issue:1

    Topics: Acetylcholine; Animals; Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; D

1957
Electrocardiographic studies on fibrillating and nonfibrillating hypothermic dogs with or without previous treatment with acetylcholine or procaine amide.
    American heart journal, 1957, Volume: 53, Issue:1

    Topics: Acetylcholine; Animals; Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; D

1957
Electrocardiographic studies on fibrillating and nonfibrillating hypothermic dogs with or without previous treatment with acetylcholine or procaine amide.
    American heart journal, 1957, Volume: 53, Issue:1

    Topics: Acetylcholine; Animals; Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; D

1957
[A new combined quinidine preparation for therapy of cardiac arrhythmia].
    Munchener medizinische Wochenschrift (1950), 1957, Jun-07, Volume: 99, Issue:23

    Topics: Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Heart Conduction System;

1957
[Clinical use of procaine amide in the treatment of cardiac arrhythmia].
    Therapie, 1957, Volume: 12, Issue:4

    Topics: Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Heart Conduction System;

1957
[Therapy of cardiac rhythm disorders by procaine amide; preliminary communication].
    Sovetskaia meditsina, 1959, Volume: 23, Issue:4

    Topics: Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Communication; Heart Cond

1959
[Use of novocaine amide in the permanent form of cardiac fibrillation].
    Zdravookhranenie Belorussii, 1963, Volume: 9

    Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Brugada Syndrome; Cardiac Conduction System Disease; Hear

1963
A comparison of tests for antifibrillatory action.
    British journal of pharmacology and chemotherapy, 1961, Volume: 17

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Complexes, Prematur

1961
Effects of antiarrhythmic drugs on external fibrillation and defibrillation thresholds.
    Cardiovascular Research Center bulletin, 1963, Volume: 1

    Topics: Anti-Allergic Agents; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduc

1963
[APROPOS OF THE USE OF NOVOCAINAMIDE IN CARDIAC ARRHYTHMIA IN CHILDREN].
    Voprosy okhrany materinstva i detstva, 1964, Volume: 9

    Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Brugada Syndrome; Cardiac Complexes, Premature; Cardiac C

1964
[Prevention of various cardiac rhythm disorders experimentally induced].
    Minerva anestesiologica, 1954, Volume: 20, Issue:11

    Topics: Arrhythmias, Cardiac; Autonomic Agents; Brugada Syndrome; Cardiac Conduction System Disease; Heart C

1954
Action of quinidine, procaine amide and other compounds on experimental atrial and ventricular arrhythmias in the dog.
    The Journal of pharmacology and experimental therapeutics, 1955, Volume: 113, Issue:4

    Topics: Animals; Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Dogs; Heart Cond

1955
Action of procainamide, quinidine and chloroquine upon the conduction system of the dog's heart (histochemical study).
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1959, Volume: 7

    Topics: Animals; Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Chloroquine; Dog

1959
Effects of procaine amide on cardiac irregularities during cyclopropane anesthesia.
    Anesthesiology, 1951, Volume: 12, Issue:3

    Topics: Anesthesia; Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Cyclopropanes

1951
A study of the effect of procaine amide hydrochloride in supraventricular arrhythmias.
    Circulation, 1951, Volume: 4, Issue:3

    Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Brugada Syndrome; Cardiac Conduction System Disease; Hear

1951
Use of pronestyl in the treatment of ectopic rhythms; treatment of 98 episodes in 78 patients.
    The American journal of medicine, 1951, Volume: 11, Issue:4

    Topics: Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Heart Conduction System;

1951
[Effect of procaine amide monohydrochloride in cardiac arrhythmia of extrasystolic origin].
    Minerva medica, 1951, Nov-17, Volume: 42, Issue:78

    Topics: Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Heart Conduction System;

1951
[Procaine amide therapy of extra-systolic ventricular arrhythmia].
    Concours medical, 1952, Mar-01, Volume: 74, Issue:9

    Topics: Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Heart Conduction System;

1952
Antiarrhythmic induced electrical storm in Brugada syndrome: a case report.
    Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2007, Volume: 12, Issue:3

    Topics: Adrenergic beta-Agonists; Amiodarone; Anti-Arrhythmia Agents; Brugada Syndrome; Defibrillators, Impl

2007
Brugada syndrome in the presence of coronary artery disease and parasympathomimetic drug therapy.
    Pacing and clinical electrophysiology : PACE, 2007, Volume: 30, Issue:8

    Topics: Anti-Arrhythmia Agents; Atropine; Brugada Syndrome; Cardiotonic Agents; Cholinesterase Inhibitors; C

2007