procainamide has been researched along with Aging in 13 studies
Procainamide: A class Ia antiarrhythmic drug that is structurally-related to PROCAINE.
procainamide : A benzamide that is 4-aminobenzamide substituted on the amide N by a 2-(diethylamino)ethyl group. It is a pharmaceutical antiarrhythmic agent used for the medical treatment of cardiac arrhythmias.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twenty Caucasian adult patients with ventricular tachycardia were treated with intravenous procainamide." | 7.67 | Influence of age, renal function and heart failure on procainamide clearance and n-acetylprocainamide serum concentrations. ( Bauer, LA; Black, D; Gensler, A; Sprinkle, J, 1989) |
| " Thus, the dosage of procainamide must be individualized for both overall renal function (GFR) and the age-related variations in renal tubular secretion that are of most note in children and the elderly." | 5.26 | Aging and renal clearance of procainamide and acetylprocainamide. ( Camacho, M; Drayer, DE; Kluger, J; Reidenberg, MM, 1980) |
| "Twenty Caucasian adult patients with ventricular tachycardia were treated with intravenous procainamide." | 3.67 | Influence of age, renal function and heart failure on procainamide clearance and n-acetylprocainamide serum concentrations. ( Bauer, LA; Black, D; Gensler, A; Sprinkle, J, 1989) |
| "Procainamide hydrochloride is a Class 1A antiarrhythmic agent administered intravenously or orally for treatment of symptomatic ventricular premature depolarizations (VPD), nonsustained ventricular tachycardia, and life-threatening ventricular arrhythmias." | 1.30 | Effect of age, gender, and race on steady state procainamide pharmacokinetics after administration of procanbid sustained-release tablets. ( Abel, RB; de Vries, TM; Eldon, MA; Koup, JR; Smithers, JA, 1998) |
| " At 3, 6, and 12 months of age, the half-life values of N-acetylprocainamide were 1." | 1.27 | Age-related pharmacokinetics of N-acetylprocainamide in rats. ( Kamath, BL; Lai, CM; Look, ZM; Stampfli, HF; Yacobi, A, 1983) |
| " Thus, the dosage of procainamide must be individualized for both overall renal function (GFR) and the age-related variations in renal tubular secretion that are of most note in children and the elderly." | 1.26 | Aging and renal clearance of procainamide and acetylprocainamide. ( Camacho, M; Drayer, DE; Kluger, J; Reidenberg, MM, 1980) |
| "Cortisone treatment thus accelerates development of adult permeability characteristics in the pulmonary epithelium." | 1.26 | Effect of cortisone on permeability of the neonatal rat lung to drugs. ( Hemberger, JA; Schanker, LS, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (84.62) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, PS | 1 |
| Chou, CC | 1 |
| Tan, AY | 1 |
| Zhou, S | 1 |
| Fishbein, MC | 1 |
| Hwang, C | 1 |
| Karagueuzian, HS | 1 |
| Lin, SF | 1 |
| Reidenberg, MM | 1 |
| Camacho, M | 1 |
| Kluger, J | 1 |
| Drayer, DE | 1 |
| Yacobi, A | 1 |
| Kamath, BL | 1 |
| Stampfli, HF | 1 |
| Look, ZM | 1 |
| Lai, CM | 1 |
| Balazs, T | 1 |
| Robinson, CJ | 1 |
| Klajman, A | 1 |
| Kafri, B | 1 |
| Shohat, T | 1 |
| Drucker, I | 1 |
| Moalem, T | 1 |
| Jaretzky, A | 1 |
| Williams, BJ | 1 |
| Abreu, ME | 1 |
| Hemberger, JA | 1 |
| Schanker, LS | 1 |
| Lowenthal, DT | 1 |
| Affrime, MB | 1 |
| Koup, JR | 1 |
| Abel, RB | 1 |
| Smithers, JA | 1 |
| Eldon, MA | 1 |
| de Vries, TM | 1 |
| Bauer, LA | 1 |
| Black, D | 1 |
| Gensler, A | 1 |
| Sprinkle, J | 1 |
| Gordon, P | 2 |
| Robelli, F | 1 |
| De Vita, C | 1 |
| Cadel, A | 1 |
3 reviews available for procainamide and Aging
| Article | Year |
|---|---|
The mechanisms of atrial fibrillation.
Topics: Aging; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Biological Clocks; Electrophysiologic T | 2006 |
Diphenylhydantoin and procainamide: normalization of suboptimal learning behavior.
Topics: Aging; Amino Acids; Animals; Brain; Learning; Male; Phenytoin; Procainamide; Rats; RNA | 1968 |
Molecular approaches to the drug enhancement of deteriorated functioning in the aged.
Topics: 1-Propanol; Aging; Amino Alcohols; Amphetamine; Animals; Brain; Cognition; Deoxyribonucleases; DNA; | 1971 |
10 other studies available for procainamide and Aging
| Article | Year |
|---|---|
Aging and renal clearance of procainamide and acetylprocainamide.
Topics: Acecainide; Adult; Aged; Aging; Child; Creatinine; Humans; Metabolic Clearance Rate; Middle Aged; Pr | 1980 |
Age-related pharmacokinetics of N-acetylprocainamide in rats.
Topics: Acecainide; Administration, Oral; Aging; Animals; Injections, Intravenous; Kinetics; Procainamide; R | 1983 |
Procainamide-induced antinuclear antibodies in beagle dogs.
Topics: Aging; Animals; Antibodies, Antinuclear; Dogs; Female; Fluorescent Antibody Technique; Male; Procain | 1983 |
The prevalence of antibodies to histones induced by procainamide in old people, in cancer patients, and in rheumatoid-like disease.
Topics: Adolescent; Adult; Aged; Aging; Antibodies, Antinuclear; Arthritis; Female; Histones; Humans; Lupus | 1983 |
Cardiotoxicity of perinatal lead exposure.
Topics: Adenylyl Cyclases; Aging; Animals; Animals, Newborn; Arrhythmias, Cardiac; Calcium; Drug Interaction | 1983 |
Effect of cortisone on permeability of the neonatal rat lung to drugs.
Topics: Aging; Aminohippuric Acids; Animals; Animals, Newborn; Cell Membrane Permeability; Cortisone; Female | 1981 |
Cardiovascular drugs for the geriatric patient.
Topics: Aged; Aging; Antihypertensive Agents; Cardiovascular Agents; Cardiovascular Physiological Phenomena; | 1981 |
Effect of age, gender, and race on steady state procainamide pharmacokinetics after administration of procanbid sustained-release tablets.
Topics: Acecainide; Administration, Oral; Adult; Aged; Aging; Anti-Arrhythmia Agents; Asian People; Black Pe | 1998 |
Influence of age, renal function and heart failure on procainamide clearance and n-acetylprocainamide serum concentrations.
Topics: Acecainide; Aged; Aging; Creatinine; Female; Heart Failure; Humans; Kidney; Kidney Diseases; Male; M | 1989 |
[Therapy of acute myocardial infarct with particular reference to arrhythmia and myocardial contractibility disorders].
Topics: Adult; Aged; Aging; Arrhythmias, Cardiac; Atropine; Cardiac Glycosides; Cortisone; Electric Counters | 1971 |