probucol has been researched along with Weight Gain in 3 studies
Probucol: A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
probucol : A dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high levels of cholesterol in blood.
Weight Gain: Increase in BODY WEIGHT over existing weight.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The probucol supplement was very potent in the antioxidative defense system, whereas naringin exhibited a comparable antioxidant capacity based on increasing the gene expressions in the antioxidant enzymes, while also increasing the hepatic SOD and CAT activities, sparing plasma vitamin E, and decreasing the hepatic mitochondrial H(2)O(2) content." | 1.31 | Comparison of antioxidant effects of naringin and probucol in cholesterol-fed rabbits. ( Bok, SH; Choi, MS; Jang, MK; Jeon, SM; Jeong, TS; Kim, YH; Nam, KT; Park, YB, 2002) |
| " Calculated bioavailability following oral administration of cyclosporin A decreased by 33% with the treatment of probucol." | 1.30 | Decrease in oral bioavailability of cyclosporin A by coadministration of probucol in rats. ( Fujimura, A; Sakamoto, K; Sugimoto, K, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zanardo, RC | 1 |
| Cruz, JW | 1 |
| Martinez, LL | 1 |
| de Oliveira, MA | 1 |
| Fortes, ZB | 1 |
| Sugimoto, K | 1 |
| Sakamoto, K | 1 |
| Fujimura, A | 1 |
| Jeon, SM | 1 |
| Bok, SH | 1 |
| Jang, MK | 1 |
| Kim, YH | 1 |
| Nam, KT | 1 |
| Jeong, TS | 1 |
| Park, YB | 1 |
| Choi, MS | 1 |
3 other studies available for probucol and Weight Gain
| Article | Year |
|---|---|
Probucol restores the defective leukocyte-endothelial interaction in experimental diabetes.
Topics: Animals; Antioxidants; Blood Circulation; Blood Glucose; Cell Migration Inhibition; Diabetes Mellitu | 2003 |
Decrease in oral bioavailability of cyclosporin A by coadministration of probucol in rats.
Topics: Administration, Oral; Animals; Anticholesteremic Agents; Biological Availability; Cholesterol; Cross | 1997 |
Comparison of antioxidant effects of naringin and probucol in cholesterol-fed rabbits.
Topics: Animals; Anticholesteremic Agents; Antioxidants; Cholesterol; Dietary Fats; Eating; Enzymes; Flavano | 2002 |