probucol has been researched along with Tachyarrhythmia in 3 studies
Probucol: A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
probucol : A dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high levels of cholesterol in blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We examined whether antioxidant and antiinflammatory treatment with probucol decreases myocardial oxidative stress and inflammation and attenuates the progression of left ventricular (LV) dysfunction and remodeling (dilatation) in tachycardia-induced HF." | 7.71 | Probucol attenuates left ventricular dysfunction and remodeling in tachycardia-induced heart failure: roles of oxidative stress and inflammation. ( Egashira, K; Hayashidani, S; Machida, Y; Nakamura, R; Takeshita, A; Takeya, M; Tsutsui, H; Utsumi, H, 2002) |
| "From published articles and adverse reactions reports filed with the FDA (available through the Freedom of Information Act), we analyzed occurrences of tachyarrhythmias and the magnitude of QTc prolongation associated with probucol therapy." | 4.79 | Probucol-associated tachyarrhythmic events and QT prolongation: importance of gender. ( Baga, JJ; Frankovich, D; Fromm, BS; Kawasaki, R; Lehmann, MH; Machado, C; Pires, LA; Reinoehl, J; Steinman, RT, 1996) |
| " We examined whether antioxidant and antiinflammatory treatment with probucol decreases myocardial oxidative stress and inflammation and attenuates the progression of left ventricular (LV) dysfunction and remodeling (dilatation) in tachycardia-induced HF." | 3.71 | Probucol attenuates left ventricular dysfunction and remodeling in tachycardia-induced heart failure: roles of oxidative stress and inflammation. ( Egashira, K; Hayashidani, S; Machida, Y; Nakamura, R; Takeshita, A; Takeya, M; Tsutsui, H; Utsumi, H, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nakamura, R | 1 |
| Egashira, K | 1 |
| Machida, Y | 1 |
| Hayashidani, S | 1 |
| Takeya, M | 1 |
| Utsumi, H | 1 |
| Tsutsui, H | 1 |
| Takeshita, A | 1 |
| Reinoehl, J | 1 |
| Frankovich, D | 1 |
| Machado, C | 1 |
| Kawasaki, R | 1 |
| Baga, JJ | 1 |
| Pires, LA | 1 |
| Steinman, RT | 1 |
| Fromm, BS | 1 |
| Lehmann, MH | 1 |
| Dage, RC | 1 |
| Anderson, BA | 1 |
| Mao, SJ | 1 |
| Koerner, JE | 1 |
1 review available for probucol and Tachyarrhythmia
| Article | Year |
|---|---|
Probucol-associated tachyarrhythmic events and QT prolongation: importance of gender.
Topics: Adult; Aged; Anticholesteremic Agents; Female; Humans; Long QT Syndrome; Male; Middle Aged; Patient | 1996 |
2 other studies available for probucol and Tachyarrhythmia
| Article | Year |
|---|---|
Probucol attenuates left ventricular dysfunction and remodeling in tachycardia-induced heart failure: roles of oxidative stress and inflammation.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cardiac Pacing, Artificial; Cardiomyopathy, Dilated | 2002 |
Probucol reduces myocardial dysfunction during reperfusion after short-term ischemia in rabbit heart.
Topics: Animals; Electrocardiography; Female; Heart; Hemodynamics; Myocardium; Probucol; Rabbits; Reperfusio | 1991 |