probucol has been researched along with Retinal Degeneration in 1 studies
Probucol: A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
probucol : A dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high levels of cholesterol in blood.
Retinal Degeneration: A retrogressive pathological change in the retina, focal or generalized, caused by genetic defects, inflammation, trauma, vascular disease, or aging. Degeneration affecting predominantly the macula lutea of the retina is MACULAR DEGENERATION. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p304)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Probucol treatment prevented diabetes-induced lesions." | 1.56 | Probucol Prevents Diabetes-Induced Retinal Neuronal Degeneration through Upregulating Nrf2. ( Chen, ZP; Liu, HW; Luo, Y; Zhou, YF, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, HW | 1 |
| Luo, Y | 1 |
| Zhou, YF | 1 |
| Chen, ZP | 1 |
1 other study available for probucol and Retinal Degeneration
| Article | Year |
|---|---|
Probucol Prevents Diabetes-Induced Retinal Neuronal Degeneration through Upregulating Nrf2.
Topics: Animals; Antioxidants; Diabetic Retinopathy; Mice; Mice, Inbred C57BL; Neurons; NF-E2-Related Factor | 2020 |