probucol has been researched along with Reperfusion Injury in 5 studies
Probucol: A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
probucol : A dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high levels of cholesterol in blood.
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study investigated the effect of probucol, a potent antioxidant, on testicular torsion/detorsion-induced ischemia/reperfusion injury attributable to excess reactive oxygen species released by neutrophils." | 7.85 | Probucol Reduces Testicular Torsion/Detorsion-Induced Ischemia/Reperfusion Injury in Rats. ( Huang, YM; Wei, SM; Zhou, J, 2017) |
| "This study investigated the effect of probucol, a potent antioxidant, on testicular torsion/detorsion-induced ischemia/reperfusion injury attributable to excess reactive oxygen species released by neutrophils." | 3.85 | Probucol Reduces Testicular Torsion/Detorsion-Induced Ischemia/Reperfusion Injury in Rats. ( Huang, YM; Wei, SM; Zhou, J, 2017) |
| "Pretreatment with cariporide in the setting of ischemia-reperfusion injury provides greater protection against the development of diastolic abnormalities than probucol when Celsior solution is used for both arrest and preservation." | 3.73 | Na+/H+ exchange inhibition and antioxidants lack additive protective effects after reperfusion injury in the working heterotopic rat heart isograft. ( Curtis, LJ; Rabkin, DG; Spotnitz, HM; Weinberg, AD, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wei, SM | 1 |
| Huang, YM | 1 |
| Zhou, J | 1 |
| Rabkin, DG | 1 |
| Curtis, LJ | 1 |
| Weinberg, AD | 1 |
| Spotnitz, HM | 1 |
| Dailly, E | 1 |
| Urien, S | 1 |
| Tillement, JP | 1 |
| Simonini, G | 1 |
| Pignone, A | 1 |
| Generini, S | 1 |
| Falcini, F | 1 |
| Cerinic, MM | 1 |
| Gabriele, S | 1 |
| Alberto, P | 1 |
| Sergio, G | 1 |
| Fernanda, F | 1 |
| Marco, MC | 1 |
| Dage, RC | 1 |
| Anderson, BA | 1 |
| Mao, SJ | 1 |
| Koerner, JE | 1 |
1 review available for probucol and Reperfusion Injury
| Article | Year |
|---|---|
Emerging potentials for an antioxidant therapy as a new approach to the treatment of systemic sclerosis.
Topics: Antioxidants; Ascorbic Acid; beta Carotene; Endothelium, Vascular; Humans; In Vitro Techniques; Mela | 2000 |
4 other studies available for probucol and Reperfusion Injury
| Article | Year |
|---|---|
Probucol Reduces Testicular Torsion/Detorsion-Induced Ischemia/Reperfusion Injury in Rats.
Topics: Animals; Anticholesteremic Agents; Male; Probucol; Rats; Rats, Sprague-Dawley; Reperfusion Injury; S | 2017 |
Na+/H+ exchange inhibition and antioxidants lack additive protective effects after reperfusion injury in the working heterotopic rat heart isograft.
Topics: Animals; Anti-Arrhythmia Agents; Antioxidants; Cardiac Volume; Compliance; Disease Models, Animal; D | 2005 |
Chain-breaking antioxidants and ferriheme-bound drugs are synergistic inhibitors of erythrocyte membrane peroxidation.
Topics: Adult; Amidines; Antioxidants; Ascorbic Acid; Chloroquine; Deferoxamine; Drug Synergism; Erythrocyte | 1998 |
Probucol reduces myocardial dysfunction during reperfusion after short-term ischemia in rabbit heart.
Topics: Animals; Electrocardiography; Female; Heart; Hemodynamics; Myocardium; Probucol; Rabbits; Reperfusio | 1991 |