probucol has been researched along with Peptic Ulcer in 1 studies
Probucol: A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
probucol : A dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high levels of cholesterol in blood.
Peptic Ulcer: Ulcer that occurs in the regions of the GASTROINTESTINAL TRACT which come into contact with GASTRIC JUICE containing PEPSIN and GASTRIC ACID. It occurs when there are defects in the MUCOSA barrier. The common forms of peptic ulcers are associated with HELICOBACTER PYLORI and the consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pretreatment with probucol (500 mg/kg, p." | 1.31 | Oxygen radicals mediate the final exacerbation of endothelin-1-induced gastric ulcer in rat. ( Goto, K; Irukayama-Tomobe, Y; Lazaratos, S; Miyauchi, T; Nakahara, A, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lazaratos, S | 1 |
| Irukayama-Tomobe, Y | 1 |
| Miyauchi, T | 1 |
| Goto, K | 1 |
| Nakahara, A | 1 |
1 other study available for probucol and Peptic Ulcer
| Article | Year |
|---|---|
Oxygen radicals mediate the final exacerbation of endothelin-1-induced gastric ulcer in rat.
Topics: Adenosine Triphosphate; Aldehydes; Allopurinol; Animals; Catalase; Deferoxamine; Disease Progression | 2001 |