probucol has been researched along with Neointima in 2 studies
Probucol: A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
probucol : A dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high levels of cholesterol in blood.
Neointima: The new and thickened layer of scar tissue that forms on a PROSTHESIS, or as a result of vessel injury especially following ANGIOPLASTY or stent placement.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this model, stent-based delivery of 1% succinobucol using a polymer-free stent platform increased neointimal formation and inflammation following coronary stenting." | 7.79 | Succinobucol-eluting stents increase neointimal thickening and peri-strut inflammation in a porcine coronary model. ( Agbani, EO; Behnisch, B; Czudaj, P; Kennedy, S; McCormick, C; McPhaden, A; Mullen, A; Oldroyd, KG; Wadsworth, RM; Watt, J, 2013) |
| "In this model, stent-based delivery of 1% succinobucol using a polymer-free stent platform increased neointimal formation and inflammation following coronary stenting." | 3.79 | Succinobucol-eluting stents increase neointimal thickening and peri-strut inflammation in a porcine coronary model. ( Agbani, EO; Behnisch, B; Czudaj, P; Kennedy, S; McCormick, C; McPhaden, A; Mullen, A; Oldroyd, KG; Wadsworth, RM; Watt, J, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yu, M | 1 |
| Xu, B | 1 |
| Kandzari, DE | 1 |
| Wu, Y | 1 |
| Yan, H | 1 |
| Chen, J | 1 |
| Qian, J | 1 |
| Qiao, S | 1 |
| Yang, Y | 1 |
| Gao, RL | 1 |
| Watt, J | 1 |
| Kennedy, S | 1 |
| McCormick, C | 1 |
| Agbani, EO | 1 |
| McPhaden, A | 1 |
| Mullen, A | 1 |
| Czudaj, P | 1 |
| Behnisch, B | 1 |
| Wadsworth, RM | 1 |
| Oldroyd, KG | 1 |
1 trial available for probucol and Neointima
| Article | Year |
|---|---|
First report of a novel polymer-free dual-drug eluting stent in de novo coronary artery disease: results of the first in human BICARE trial.
Topics: Cardiovascular Agents; China; Coronary Angiography; Coronary Restenosis; Coronary Stenosis; Drug Com | 2014 |
1 other study available for probucol and Neointima
| Article | Year |
|---|---|
Succinobucol-eluting stents increase neointimal thickening and peri-strut inflammation in a porcine coronary model.
Topics: Animals; Cardiovascular Agents; Cattle; Cell Survival; Cells, Cultured; Coronary Vessels; Dose-Respo | 2013 |