probucol has been researched along with Mitochondrial Diseases in 2 studies
Probucol: A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
probucol : A dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high levels of cholesterol in blood.
Mitochondrial Diseases: Diseases caused by abnormal function of the MITOCHONDRIA. They may be caused by mutations, acquired or inherited, in mitochondrial DNA or in nuclear genes that code for mitochondrial components. They may also be the result of acquired mitochondria dysfunction due to adverse effects of drugs, infections, or other environmental causes.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Peng, M | 1 |
| Ostrovsky, J | 1 |
| Kwon, YJ | 1 |
| Polyak, E | 1 |
| Licata, J | 1 |
| Tsukikawa, M | 1 |
| Marty, E | 1 |
| Thomas, J | 1 |
| Felix, CA | 1 |
| Xiao, R | 1 |
| Zhang, Z | 2 |
| Gasser, DL | 2 |
| Argon, Y | 1 |
| Falk, MJ | 2 |
| Rappaport, EF | 1 |
2 other studies available for probucol and Mitochondrial Diseases
| Article | Year |
|---|---|
Inhibiting cytosolic translation and autophagy improves health in mitochondrial disease.
Topics: Animals; Autophagy; Cell Survival; Cycloheximide; Cytosol; Disease Models, Animal; Electron Transpor | 2015 |
Cross-platform expression microarray performance in a mouse model of mitochondrial disease therapy.
Topics: Animals; Antioxidants; Computational Biology; Disease Models, Animal; Gene Expression Profiling; Mic | 2010 |