probucol has been researched along with Malaria in 3 studies
Probucol: A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
probucol : A dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high levels of cholesterol in blood.
Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study demonstrated that probucol has some impact on malaria by oxidative stress through the induction of host plasma vitamin E deficiency." | 7.83 | Probucol dramatically enhances dihydroartemisinin effect in murine malaria. ( Anh, DT; Ishida, N; Kume, A; Shichiri, M; Suzuki, H, 2016) |
| "Probucol pre-treatment for 2 weeks and treatment throughout the infection rescued from death of mice infected with Plasmodium yoelii XL-17 or P." | 5.42 | Probucol-Induced α-Tocopherol Deficiency Protects Mice against Malaria Infection. ( Hagihara, Y; Herbas, MS; Ishida, N; Kume, A; Shichiri, M; Suzuki, H; Yoshida, Y, 2015) |
| "This study demonstrated that probucol has some impact on malaria by oxidative stress through the induction of host plasma vitamin E deficiency." | 3.83 | Probucol dramatically enhances dihydroartemisinin effect in murine malaria. ( Anh, DT; Ishida, N; Kume, A; Shichiri, M; Suzuki, H, 2016) |
| "Probucol pre-treatment for 2 weeks and treatment throughout the infection rescued from death of mice infected with Plasmodium yoelii XL-17 or P." | 1.42 | Probucol-Induced α-Tocopherol Deficiency Protects Mice against Malaria Infection. ( Hagihara, Y; Herbas, MS; Ishida, N; Kume, A; Shichiri, M; Suzuki, H; Yoshida, Y, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Herbas, MS | 2 |
| Shichiri, M | 3 |
| Ishida, N | 3 |
| Kume, A | 3 |
| Hagihara, Y | 1 |
| Yoshida, Y | 1 |
| Suzuki, H | 3 |
| Anh, DT | 1 |
3 other studies available for probucol and Malaria
| Article | Year |
|---|---|
Probucol-Induced α-Tocopherol Deficiency Protects Mice against Malaria Infection.
Topics: alpha-Tocopherol; Animals; Antimalarials; Antioxidants; Artemisinins; Drug Administration Schedule; | 2015 |
Effect of anti-hyperlipidemia drugs on the alpha-tocopherol concentration and their potential for murine malaria infection.
Topics: alpha-Tocopherol; Animals; Anticholesteremic Agents; Antimalarials; Berberine; Cholestyramine Resin; | 2016 |
Probucol dramatically enhances dihydroartemisinin effect in murine malaria.
Topics: Animals; Antimalarials; Artemisinins; Chemoprevention; Disease Models, Animal; Malaria; Male; Mice, | 2016 |