probucol has been researched along with Lung Neoplasms in 5 studies
Probucol: A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
probucol : A dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high levels of cholesterol in blood.
Lung Neoplasms: Tumors or cancer of the LUNG.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The directed nanoassembly of probucol results in the "DNP" system, which greatly improves the oral delivery of probucol and subsequently leads to a novel therapeutic efficacy of probucol in the suppression of lung metastasis of breast cancer." | 7.80 | Nanoassembly of probucol enables novel therapeutic efficacy in the suppression of lung metastasis of breast cancer. ( Cao, H; He, X; Jiang, S; Li, Y; Liu, Z; Yu, H; Zhang, Z, 2014) |
| " Furthermore, the oral bioavailability of SCB was greatly improved about 13-fold by SN, and the biodistribution in major organs was evidently enhanced." | 5.42 | Hydrophobic interaction mediating self-assembled nanoparticles of succinobucol suppress lung metastasis of breast cancer by inhibition of VCAM-1 expression. ( Cao, H; Chen, L; Gu, W; He, X; Li, Y; Yin, Q; Yu, H; Zhang, Z; Zhao, S, 2015) |
| " The directed nanoassembly of probucol results in the "DNP" system, which greatly improves the oral delivery of probucol and subsequently leads to a novel therapeutic efficacy of probucol in the suppression of lung metastasis of breast cancer." | 3.80 | Nanoassembly of probucol enables novel therapeutic efficacy in the suppression of lung metastasis of breast cancer. ( Cao, H; He, X; Jiang, S; Li, Y; Liu, Z; Yu, H; Zhang, Z, 2014) |
| "Cancer metastasis is the main cause for the high mortality in breast cancer patients." | 1.43 | pH-Responsive Wormlike Micelles with Sequential Metastasis Targeting Inhibit Lung Metastasis of Breast Cancer. ( Bao, X; Cao, H; He, X; Li, Y; Yin, Q; Yu, H; Zhang, Z, 2016) |
| " Furthermore, the oral bioavailability of SCB was greatly improved about 13-fold by SN, and the biodistribution in major organs was evidently enhanced." | 1.42 | Hydrophobic interaction mediating self-assembled nanoparticles of succinobucol suppress lung metastasis of breast cancer by inhibition of VCAM-1 expression. ( Cao, H; Chen, L; Gu, W; He, X; Li, Y; Yin, Q; Yu, H; Zhang, Z; Zhao, S, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, Z | 5 |
| Cao, H | 4 |
| Jiang, S | 1 |
| Liu, Z | 1 |
| He, X | 4 |
| Yu, H | 4 |
| Li, Y | 4 |
| Zhao, S | 1 |
| Yin, Q | 3 |
| Gu, W | 1 |
| Chen, L | 1 |
| Bao, X | 1 |
| Dan, Z | 1 |
| Zou, L | 1 |
| Zeng, L | 1 |
| Xu, Y | 1 |
| Xu, M | 1 |
| Zhong, D | 1 |
| Shen, Q | 1 |
| Zhang, P | 1 |
| Zarkovic, M | 1 |
| Qin, X | 1 |
| Nakatsuru, Y | 1 |
| Zhang, S | 1 |
| Yamazaki, Y | 1 |
| Oda, H | 1 |
| Ishikawa, T | 2 |
5 other studies available for probucol and Lung Neoplasms
| Article | Year |
|---|---|
Nanoassembly of probucol enables novel therapeutic efficacy in the suppression of lung metastasis of breast cancer.
Topics: Animals; Breast Neoplasms; Female; Humans; Lung Neoplasms; Mice; Microscopy, Electron, Transmission; | 2014 |
Hydrophobic interaction mediating self-assembled nanoparticles of succinobucol suppress lung metastasis of breast cancer by inhibition of VCAM-1 expression.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Apoptosis; Biological Availability; Breast Neo | 2015 |
pH-Responsive Wormlike Micelles with Sequential Metastasis Targeting Inhibit Lung Metastasis of Breast Cancer.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Disease Models, A | 2016 |
A pH-Responsive Host-guest Nanosystem Loading Succinobucol Suppresses Lung Metastasis of Breast Cancer.
Topics: Animals; Antineoplastic Agents; beta-Cyclodextrins; Breast Neoplasms; Cell Movement; Disease Models, | 2016 |
Inhibitory effect of probucol on benzo[a]pyrene induced lung tumorigenesis.
Topics: Animals; Anticarcinogenic Agents; Anticholesteremic Agents; Benzo(a)pyrene; Body Weight; Carcinogens | 1995 |