probucol has been researched along with Liver Neoplasms in 4 studies
Probucol: A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
probucol : A dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high levels of cholesterol in blood.
Liver Neoplasms: Tumors or cancer of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Probucol did not increase human SR-BI protein in the liver of transgenic mice carrying the entire human SR-BI genome." | 1.33 | Probucol enhances the expression of human hepatic scavenger receptor class B type I, possibly through a species-specific mechanism. ( Hirano, K; Ikegami, C; Koseki, M; Maruyama, T; Masuda, D; Matsuura, F; Nakagawa-Toyama, Y; Shimomura, I; Tsujii, K; Ueda, Y; Yamashita, S; Zhang, Z, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jendralla, H | 1 |
| Granzer, E | 1 |
| von Kerekjarto, B | 1 |
| Krause, R | 1 |
| Schacht, U | 1 |
| Baader, E | 1 |
| Bartmann, W | 1 |
| Beck, G | 1 |
| Bergmann, A | 1 |
| Kesseler, K | 1 |
| Hirano, K | 1 |
| Ikegami, C | 1 |
| Tsujii, K | 1 |
| Zhang, Z | 1 |
| Matsuura, F | 1 |
| Nakagawa-Toyama, Y | 1 |
| Koseki, M | 1 |
| Masuda, D | 1 |
| Maruyama, T | 1 |
| Shimomura, I | 1 |
| Ueda, Y | 1 |
| Yamashita, S | 1 |
| Pico, I | 1 |
| Myara, I | 1 |
| Pech-Amsellem, MA | 1 |
| Vedie, B | 1 |
| Chappey, B | 1 |
| Moatti, N | 1 |
| Pfeuffer, MA | 1 |
| Richard, BM | 1 |
| Pittman, RC | 1 |
4 other studies available for probucol and Liver Neoplasms
| Article | Year |
|---|---|
Synthesis and biological activity of new HMG-CoA reductase inhibitors. 3. Lactones of 6-phenoxy-3,5-dihydroxyhexanoic acids.
Topics: Animals; Anticholesteremic Agents; Caproates; Carcinoma, Hepatocellular; Cholesterol; Dogs; Humans; | 1991 |
Probucol enhances the expression of human hepatic scavenger receptor class B type I, possibly through a species-specific mechanism.
Topics: Adult; Animals; Anticholesteremic Agents; Atherosclerosis; Carcinoma, Hepatocellular; Cell Line, Tum | 2005 |
Oxidative modification of low-density lipoprotein by the human hepatoma cell line HepG2.
Topics: Antioxidants; Butylated Hydroxytoluene; Chromatography, Ion Exchange; Electrophoresis, Agar Gel; Ele | 1996 |
Probucol increases the selective uptake of HDL cholesterol esters by Hep G2 human hepatoma cells.
Topics: Carcinoma, Hepatocellular; Cell Membrane; Cholesterol Esters; Cholesterol, HDL; Cholesterol, LDL; Do | 1992 |