probucol has been researched along with Kidney Neoplasms in 2 studies
Probucol: A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
probucol : A dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high levels of cholesterol in blood.
Kidney Neoplasms: Tumors or cancers of the KIDNEY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Probucol fed diet pretreatment also resulted a significant and dose dependent inhibition of Fe-NTA induced renal ornithine decarboxylase (ODC) activity." | 1.34 | Probucol modulates iron nitrilotriacetate (Fe-NTA)-dependent renal carcinogenesis and hyperproliferative response: diminution of oxidative stress. ( Iqbal, M; Okada, S; Okazaki, Y, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Iqbal, M | 1 |
| Okazaki, Y | 1 |
| Okada, S | 1 |
| Qin, X | 1 |
| Zhang, S | 1 |
| Zarkovic, M | 1 |
| Yamazaki, Y | 1 |
| Oda, H | 1 |
| Nakatsuru, Y | 1 |
| Ishikawa, T | 2 |
2 other studies available for probucol and Kidney Neoplasms
| Article | Year |
|---|---|
Probucol modulates iron nitrilotriacetate (Fe-NTA)-dependent renal carcinogenesis and hyperproliferative response: diminution of oxidative stress.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Carcinogens; Cell Proliferation; Drug Evaluation, Pr | 2007 |
Inhibitory effect of probucol on nephrotoxicity induced by ferric nitrilotriacetate (Fe-NTA) in rats.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Diet; Ferric Compounds; Kidney; Kidney Cortex; Kidney | 1995 |