Page last updated: 2024-11-03

probucol and Ischemia

probucol has been researched along with Ischemia in 5 studies

Probucol: A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
probucol : A dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high levels of cholesterol in blood.

Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.

Research Excerpts

ExcerptRelevanceReference
"Probucol and antioxidant vitamins rescue cigarette smoke-dependent impairment of ischemia-induced neovascularization."7.76Probucol and antioxidant vitamins rescue ischemia-induced neovascularization in mice exposed to cigarette smoke: potential role of endothelial progenitor cells. ( Dussault, S; Groleau, J; Haddad, P; Maingrette, F; Ménard, C; Michaud, SE; Rivard, A; Turgeon, J, 2010)
"Probucol and antioxidant vitamins rescue cigarette smoke-dependent impairment of ischemia-induced neovascularization."3.76Probucol and antioxidant vitamins rescue ischemia-induced neovascularization in mice exposed to cigarette smoke: potential role of endothelial progenitor cells. ( Dussault, S; Groleau, J; Haddad, P; Maingrette, F; Ménard, C; Michaud, SE; Rivard, A; Turgeon, J, 2010)
"The effects of antioxidant therapy with probucol were evaluated in rats subjected to 1 h renal ischemia and to 24 h reperfusion."3.67Ischemic acute renal failure and antioxidant therapy in the rat. The relation between glomerular and tubular dysfunction. ( Bird, JE; Blantz, RC; Milhoan, K; Mundy, CA; Parthasarathy, S; Wilson, CB; Young, SG, 1988)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Turgeon, J1
Dussault, S1
Haddad, P1
Groleau, J1
Ménard, C1
Michaud, SE1
Maingrette, F1
Rivard, A1
Veryard, C1
Batra, S1
Srivastava, S1
Singh, K1
Chander, R1
Khanna, AK1
Bhaduri, AP1
Bird, JE2
Evan, AP1
Peterson, OW1
Blantz, RC2
Milhoan, K1
Wilson, CB1
Young, SG1
Mundy, CA1
Parthasarathy, S1

Other Studies

5 other studies available for probucol and Ischemia

ArticleYear
Probucol and antioxidant vitamins rescue ischemia-induced neovascularization in mice exposed to cigarette smoke: potential role of endothelial progenitor cells.
    Atherosclerosis, 2010, Volume: 208, Issue:2

    Topics: Animals; Antioxidants; Cells, Cultured; Endothelial Cells; Flow Cytometry; Ischemia; Mice; Mice, Inb

2010
American Heart Association - Scientific Sessions 2006. Cell therapies for ischemic tissues and treatments for lipid metabolism disorders.
    IDrugs : the investigational drugs journal, 2007, Volume: 10, Issue:1

    Topics: Animals; Cell- and Tissue-Based Therapy; Cholesterol, LDL; Coronary Disease; Endothelial Cells; Eryt

2007
Syntheses and biological evaluation of 3-substituted amino-1-aryl-6-hydroxy-hex-2-ene-1-ones as antioxidant and hypolipidemic agents.
    Bioorganic & medicinal chemistry, 2000, Volume: 8, Issue:8

    Topics: Alkenes; Animals; Antioxidants; Cholesterol; Cholesterol, LDL; Commiphora; Copper; Ethylamines; Hype

2000
Early events in ischemic renal failure in the rat: effects of antioxidant therapy.
    Kidney international, 1989, Volume: 35, Issue:6

    Topics: Animals; Antioxidants; Glomerular Filtration Rate; Ischemia; Kidney; Kidney Tubules, Proximal; Male;

1989
Ischemic acute renal failure and antioxidant therapy in the rat. The relation between glomerular and tubular dysfunction.
    The Journal of clinical investigation, 1988, Volume: 81, Issue:5

    Topics: Acute Kidney Injury; Animals; Chemical Phenomena; Chemistry; Glomerular Filtration Rate; Inulin; Isc

1988