probucol has been researched along with Intermittent Claudication in 1 studies
Probucol: A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
probucol : A dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high levels of cholesterol in blood.
Intermittent Claudication: A symptom complex characterized by pain and weakness in SKELETAL MUSCLE group associated with exercise, such as leg pain and weakness brought on by walking. Such muscle limpness disappears after a brief rest and is often relates to arterial STENOSIS; muscle ISCHEMIA; and accumulation of LACTATE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A total of 335 patients (206 men; mean age 72+/-9 years) with intermittent claudication were randomized according to a 2x2 factorial design to 1 of the 4 groups: probucol, placebo, EVBT, and EVBT+probucol." | 5.11 | Effects of probucol versus aspirin and versus brachytherapy on restenosis after femoropopliteal angioplasty: the PAB randomized multicenter trial. ( Alerci, M; Amann-Vesti, B; Aschwanden, M; Baumgartner, I; Bernier, J; Canevascini, R; Cozzi, L; Do, DD; Gallino, A; Greiner, R; Jacob, AL; Jäger, K; Kann, R; Kellner, F; Mahler, F; Schneider, E; Segatto, JM; Studer, G; Triller, J; Tutta, P, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gallino, A | 1 |
| Do, DD | 1 |
| Alerci, M | 1 |
| Baumgartner, I | 1 |
| Cozzi, L | 1 |
| Segatto, JM | 1 |
| Bernier, J | 1 |
| Tutta, P | 1 |
| Kellner, F | 1 |
| Triller, J | 1 |
| Schneider, E | 1 |
| Amann-Vesti, B | 1 |
| Studer, G | 1 |
| Jäger, K | 1 |
| Aschwanden, M | 1 |
| Canevascini, R | 1 |
| Jacob, AL | 1 |
| Kann, R | 1 |
| Greiner, R | 1 |
| Mahler, F | 1 |
1 trial available for probucol and Intermittent Claudication
| Article | Year |
|---|---|
Effects of probucol versus aspirin and versus brachytherapy on restenosis after femoropopliteal angioplasty: the PAB randomized multicenter trial.
Topics: Aged; Aged, 80 and over; Analysis of Variance; Angioplasty, Balloon; Arterial Occlusive Diseases; As | 2004 |