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probucol and Hypertrophy, Right Ventricular

probucol has been researched along with Hypertrophy, Right Ventricular in 1 studies

Probucol: A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
probucol : A dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high levels of cholesterol in blood.

Hypertrophy, Right Ventricular: Enlargement of the RIGHT VENTRICLE of the heart. This increase in ventricular mass is often attributed to PULMONARY HYPERTENSION and is a contributor to cardiovascular morbidity and mortality.

Research Excerpts

ExcerptRelevanceReference
" In this work, we studied the effect of treatment with a 1% probucol diet on pulmonary hypertension induced by monocrotaline (MCT) in rats."7.70Chronic treatment with probucol effectively inhibits progression of pulmonary hypertension in rats. ( Irukayama-Tomobe, Y; Miyauchi, T; Sakai, S, 2000)
" In this work, we studied the effect of treatment with a 1% probucol diet on pulmonary hypertension induced by monocrotaline (MCT) in rats."3.70Chronic treatment with probucol effectively inhibits progression of pulmonary hypertension in rats. ( Irukayama-Tomobe, Y; Miyauchi, T; Sakai, S, 2000)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Irukayama-Tomobe, Y1
Sakai, S1
Miyauchi, T1

Other Studies

1 other study available for probucol and Hypertrophy, Right Ventricular

ArticleYear
Chronic treatment with probucol effectively inhibits progression of pulmonary hypertension in rats.
    Life sciences, 2000, Sep-08, Volume: 67, Issue:16

    Topics: Animals; Anticholesteremic Agents; Blood Pressure; Diet; Disease Progression; Hypertension, Pulmonar

2000