Page last updated: 2024-11-03

probucol and Hypertrophy, Left Ventricular

probucol has been researched along with Hypertrophy, Left Ventricular in 1 studies

Probucol: A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
probucol : A dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high levels of cholesterol in blood.

Hypertrophy, Left Ventricular: Enlargement of the LEFT VENTRICLE of the heart. This increase in ventricular mass is attributed to sustained abnormal pressure or volume loads and is a contributor to cardiovascular morbidity and mortality.

Research Excerpts

ExcerptRelevanceReference
"The lipid-lowering agent probucol may be efficacious, through its antioxidant properties, to limit and reverse the vascular endothelial dysfunction associated with left ventricular hypertrophy (LVH)."7.73Role of probucol on endothelial dysfunction of epicardial coronary arteries associated with left ventricular hypertrophy. ( Aubin, MC; Carrier, M; Perrault, LP; Shi, YF; Tardif, JC, 2006)
"The lipid-lowering agent probucol may be efficacious, through its antioxidant properties, to limit and reverse the vascular endothelial dysfunction associated with left ventricular hypertrophy (LVH)."3.73Role of probucol on endothelial dysfunction of epicardial coronary arteries associated with left ventricular hypertrophy. ( Aubin, MC; Carrier, M; Perrault, LP; Shi, YF; Tardif, JC, 2006)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aubin, MC1
Carrier, M1
Shi, YF1
Tardif, JC1
Perrault, LP1

Other Studies

1 other study available for probucol and Hypertrophy, Left Ventricular

ArticleYear
Role of probucol on endothelial dysfunction of epicardial coronary arteries associated with left ventricular hypertrophy.
    Journal of cardiovascular pharmacology, 2006, Volume: 47, Issue:5

    Topics: Angiotensin II; Animals; Antioxidants; Bradykinin; Coronary Vessels; Cyclic GMP; Endothelium, Vascul

2006