probucol and Hyperoxia studies

Probucol: A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
probucol : A dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high levels of cholesterol in blood.

Hyperoxia: An abnormal increase in the amount of oxygen in the tissues and organs.

Research Excerpts

Excerpt	Relevance	Reference
"Probucol treatment significantly decreased both the number of inflammatory cells in the bronchoalveolar lavage fluid and the degree of lung injury in hyperoxia-exposed mice."	5.46	Probucol attenuates hyperoxia-induced lung injury in mice. ( Hamada, N; Harada-Ikeda, C; Kawaguchi, T; Kuwano, K; Maeyama, T; Nakanishi, Y; Suetsugu-Ogata, S; Suzuki, K; Yanagihara, T; Yokoyama, T, 2017)
"Probucol treatment significantly decreased both the number of inflammatory cells in the bronchoalveolar lavage fluid and the degree of lung injury in hyperoxia-exposed mice."	1.46	Probucol attenuates hyperoxia-induced lung injury in mice. ( Hamada, N; Harada-Ikeda, C; Kawaguchi, T; Kuwano, K; Maeyama, T; Nakanishi, Y; Suetsugu-Ogata, S; Suzuki, K; Yanagihara, T; Yokoyama, T, 2017)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (100.00)	24.3611
2020's	0 (0.00)	2.80

probucol and Hyperoxia

Research Excerpts

Research

Studies (1)

Authors

Other Studies

Authors	Studies
Kawaguchi, T	1
Yanagihara, T	1
Yokoyama, T	1
Suetsugu-Ogata, S	1
Hamada, N	1
Harada-Ikeda, C	1
Suzuki, K	1
Maeyama, T	1
Kuwano, K	1
Nakanishi, Y	1