probucol has been researched along with Heart Diseases in 6 studies
Probucol: A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
probucol : A dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high levels of cholesterol in blood.
Heart Diseases: Pathological conditions involving the HEART including its structural and functional abnormalities.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Probucol has been reported to completely prevent DOX-induced cardiomyopathy." | 1.32 | New aspects in probucol cardioprotection against doxorubicin-induced cardiotoxicity. ( Ali, AA; El-Demerdash, E; Osman, AM; Sayed-Ahmed, MM, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Saleem, MT | 1 |
| Chetty, MC | 1 |
| Kavimani, S | 1 |
| Stix, G | 1 |
| El-Demerdash, E | 1 |
| Ali, AA | 1 |
| Sayed-Ahmed, MM | 1 |
| Osman, AM | 1 |
| Recio-Mayoral, A | 1 |
| Kaski, JC | 1 |
| McMurray, JJ | 1 |
| Horowitz, J | 1 |
| van Veldhuisen, DJ | 1 |
| Remme, WJ | 1 |
| Marshall, FN | 1 |
| Miettinen, TA | 1 |
| Huttunen, JK | 1 |
| Kuusi, T | 1 |
| Kumlin, T | 1 |
| Mattila, S | 1 |
| Naukkarinen, V | 1 |
| Strandberg, T | 1 |
1 review available for probucol and Heart Diseases
| Article | Year |
|---|---|
Pharmacology and toxicology of probucol.
Topics: Animals; Arteriosclerosis; Cholesterol; Dogs; Feces; Heart Diseases; Macaca fascicularis; Macaca mul | 1982 |
5 other studies available for probucol and Heart Diseases
| Article | Year |
|---|---|
Antioxidants and tumor necrosis factor alpha-inhibiting activity of sesame oil against doxorubicin-induced cardiotoxicity.
Topics: Administration, Oral; Animals; Antibiotics, Antineoplastic; Antioxidants; Dose-Response Relationship | 2014 |
Signal jammer. An academic experiment leads to a new class of drug for attacking heart disease.
Topics: Anticholesteremic Agents; Antioxidants; Arteriosclerosis; Clinical Trials as Topic; Drug Industry; H | 2003 |
New aspects in probucol cardioprotection against doxorubicin-induced cardiotoxicity.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Algorithms; Animals; Antibiotics, Antineoplastic; Ant | 2003 |
Clinical trials update from the European Society of Cardiology Congress in Vienna, 2007: PROSPECT, EVEREST, ARISE, ALOFT, FINESSE, Prague-8, CARESS in MI and ACUITY.
Topics: Abciximab; Acute Coronary Syndrome; Amides; Antibodies, Monoclonal; Benzazepines; Clinical Trials as | 2007 |
Clinical experience with probucol with special emphasis on mode of action and long-term treatment.
Topics: Cholesterol; Coronary Disease; Electrocardiography; Heart Diseases; Humans; Hypercholesterolemia; Ph | 1982 |