probucol has been researched along with Eyelid Diseases in 4 studies
Probucol: A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
probucol : A dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high levels of cholesterol in blood.
Eyelid Diseases: Diseases involving the EYELIDS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 66-year-old male heterozygous familial hypercholesterolemia (FH) patient with significant coronary atherosclerosis has been treated by us with probucol (1000 mg daily) for eight years." | 5.29 | Long-term probucol treatment results in regression of xanthomas, but in progression of coronary atherosclerosis in a heterozygous patient with familial hypercholesterolemia. ( Kajinami, K; Koizumi, J; Mabuchi, H; Nishitsuji, M; Shimizu, M; Takeda, Y, 1996) |
| "A 66-year-old male heterozygous familial hypercholesterolemia (FH) patient with significant coronary atherosclerosis has been treated by us with probucol (1000 mg daily) for eight years." | 1.29 | Long-term probucol treatment results in regression of xanthomas, but in progression of coronary atherosclerosis in a heterozygous patient with familial hypercholesterolemia. ( Kajinami, K; Koizumi, J; Mabuchi, H; Nishitsuji, M; Shimizu, M; Takeda, Y, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ishihara-Yusa, S | 1 |
| Fujimura, T | 1 |
| Lyu, C | 1 |
| Sugawara, M | 1 |
| Sakamoto, K | 1 |
| Aiba, S | 1 |
| Kajinami, K | 1 |
| Nishitsuji, M | 1 |
| Takeda, Y | 1 |
| Shimizu, M | 1 |
| Koizumi, J | 1 |
| Mabuchi, H | 1 |
| Nakamura, T | 1 |
| Ueyama, Y | 1 |
| Funahashi, T | 1 |
| Yamashita, S | 1 |
| Takemura, KK | 1 |
| Kubo, M | 1 |
| Yamada, K | 1 |
| Matsuzawa, Y | 1 |
| Harris, RS | 1 |
| Gilmore, HR | 1 |
| Bricker, LA | 1 |
| Kiem, IM | 1 |
| Rubin, E | 1 |
1 trial available for probucol and Eyelid Diseases
| Article | Year |
|---|---|
Long-term oral administration of probucol (4,4'-(isopropylidenedithio) bis(2,6-di-t-butylphenol)) (DH-581) in the management of hypercholesterolemia.
Topics: Administration, Oral; Adult; Anticholesteremic Agents; Chemical Phenomena; Chemistry; Clinical Trial | 1974 |
3 other studies available for probucol and Eyelid Diseases
| Article | Year |
|---|---|
Successful treatment of multiple eruptive adult xanthogranuloma concomitant with xanthelasma palpebrarum with probucol.
Topics: Eyelid Diseases; Eyelids; Female; Granuloma; Humans; Middle Aged; Neck; Probucol; Skin; Treatment Ou | 2019 |
Long-term probucol treatment results in regression of xanthomas, but in progression of coronary atherosclerosis in a heterozygous patient with familial hypercholesterolemia.
Topics: Aged; Anticholesteremic Agents; Cholesterol, HDL; Cholesterol, LDL; Coronary Angiography; Coronary A | 1996 |
Non-macrophage-related accumulation of cholesterol during probucol treatment in familial hypercholesterolemia: report of two cases.
Topics: Adult; Cholesterol; Eyelid Diseases; Humans; Hyperlipoproteinemia Type II; Macrophages; Male; Middle | 1992 |