probucol has been researched along with Edema in 2 studies
Probucol: A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
probucol : A dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high levels of cholesterol in blood.
Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Overt pain-like behaviors were determined by the number of abdominal writhings induced by phenyl-p-benzoquinone and acetic acid." | 7.85 | Probucol attenuates overt pain-like behavior and carrageenan-induced inflammatory hyperalgesia and leukocyte recruitment by inhibiting NF-кB activation and cytokine production without antioxidant effects. ( Alves-Filho, JC; Antunes, MM; Casagrande, R; Cunha, FQ; Cunha, TM; Manchope, MF; Menezes, GB; Staurengo-Ferrari, L; Verri, WA; Zucoloto, AZ, 2017) |
| "Overt pain-like behaviors were determined by the number of abdominal writhings induced by phenyl-p-benzoquinone and acetic acid." | 3.85 | Probucol attenuates overt pain-like behavior and carrageenan-induced inflammatory hyperalgesia and leukocyte recruitment by inhibiting NF-кB activation and cytokine production without antioxidant effects. ( Alves-Filho, JC; Antunes, MM; Casagrande, R; Cunha, FQ; Cunha, TM; Manchope, MF; Menezes, GB; Staurengo-Ferrari, L; Verri, WA; Zucoloto, AZ, 2017) |
| "Because atherosclerosis is an inflammatory process involving a series of pathological events such as dyslipidemia, oxidative stress, and blood clotting mechanisms, we hereby report the synthesis and evaluation of novel compounds in which antioxidant, anti-inflammatory, and squalene synthase (SQS) inhibitory/hypolipidemic activities are combined in simple molecules through design." | 1.40 | Design of novel potent antihyperlipidemic agents with antioxidant/anti-inflammatory properties: exploiting phenothiazine's strong antioxidant activity. ( Kourounakis, AP; Matralis, AN, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Matralis, AN | 1 |
| Kourounakis, AP | 1 |
| Zucoloto, AZ | 1 |
| Manchope, MF | 1 |
| Staurengo-Ferrari, L | 1 |
| Alves-Filho, JC | 1 |
| Cunha, TM | 1 |
| Antunes, MM | 1 |
| Menezes, GB | 1 |
| Cunha, FQ | 1 |
| Casagrande, R | 1 |
| Verri, WA | 1 |
2 other studies available for probucol and Edema
| Article | Year |
|---|---|
Design of novel potent antihyperlipidemic agents with antioxidant/anti-inflammatory properties: exploiting phenothiazine's strong antioxidant activity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Atherosclerosis; Biphenyl Compounds; | 2014 |
Probucol attenuates overt pain-like behavior and carrageenan-induced inflammatory hyperalgesia and leukocyte recruitment by inhibiting NF-кB activation and cytokine production without antioxidant effects.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; Benzoquinones; Carrage | 2017 |