Page last updated: 2024-11-03

probucol and Degenerative Diseases, Central Nervous System

probucol has been researched along with Degenerative Diseases, Central Nervous System in 1 studies

Probucol: A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
probucol : A dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high levels of cholesterol in blood.

Research Excerpts

ExcerptRelevanceReference
"To enhance the bioavailability and brain uptake of probucol and examine whether it attenuates neuroinflammation and neurodegeneration by utilizing a sodium alginate nanoencapsulation technique."7.88Sodium alginate capsulation increased brain delivery of probucol and suppressed neuroinflammation and neurodegeneration. ( Al-Salami, H; Brook, E; D'Alonzo, Z; Fimognari, N; Graneri, L; Lam, V; Mamo, JC; Mooranian, A; Nesbit, M; Stephenson, A; Takechi, R, 2018)
"To enhance the bioavailability and brain uptake of probucol and examine whether it attenuates neuroinflammation and neurodegeneration by utilizing a sodium alginate nanoencapsulation technique."3.88Sodium alginate capsulation increased brain delivery of probucol and suppressed neuroinflammation and neurodegeneration. ( Al-Salami, H; Brook, E; D'Alonzo, Z; Fimognari, N; Graneri, L; Lam, V; Mamo, JC; Mooranian, A; Nesbit, M; Stephenson, A; Takechi, R, 2018)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mamo, JC1
Lam, V1
Al-Salami, H1
Brook, E1
Mooranian, A1
Nesbit, M1
Graneri, L1
D'Alonzo, Z1
Fimognari, N1
Stephenson, A1
Takechi, R1

Other Studies

1 other study available for probucol and Degenerative Diseases, Central Nervous System

ArticleYear
Sodium alginate capsulation increased brain delivery of probucol and suppressed neuroinflammation and neurodegeneration.
    Therapeutic delivery, 2018, Volume: 9, Issue:10

    Topics: Alginates; Animals; Biological Availability; Blood-Brain Barrier; Capsules; Diet, High-Fat; Disease

2018