Page last updated: 2024-11-03

probucol and Cirrhosis, Liver

probucol has been researched along with Cirrhosis, Liver in 2 studies

Probucol: A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
probucol : A dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high levels of cholesterol in blood.

Research Excerpts

ExcerptRelevanceReference
"Probucol has antioxidant effects and inhibits inflammation."1.51Probucol ameliorates hepatic stellate cell activation and autophagy is associated with farnesoid X receptor. ( Hu, Z; Shen, X; Song, Z; Wei, Z; Wu, S; Yang, R; Zhang, P, 2019)
"1."1.40Probucol attenuates ethanol-induced liver fibrosis in rats by inhibiting oxidative stress, extracellular matrix protein accumulation and cytokine production. ( Lin, Y; Su, X; Wang, Y; Yang, X; Yu, R; Zheng, C; Zhou, G, 2014)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yang, R1
Hu, Z1
Zhang, P1
Wu, S1
Song, Z1
Shen, X1
Wei, Z1
Su, X1
Wang, Y1
Zhou, G1
Yang, X1
Yu, R1
Lin, Y1
Zheng, C1

Other Studies

2 other studies available for probucol and Cirrhosis, Liver

ArticleYear
Probucol ameliorates hepatic stellate cell activation and autophagy is associated with farnesoid X receptor.
    Journal of pharmacological sciences, 2019, Volume: 139, Issue:2

    Topics: Animals; Antioxidants; Autophagy; Cell Line; Cells, Cultured; Hepatic Stellate Cells; Liver; Liver C

2019
Probucol attenuates ethanol-induced liver fibrosis in rats by inhibiting oxidative stress, extracellular matrix protein accumulation and cytokine production.
    Clinical and experimental pharmacology & physiology, 2014, Volume: 41, Issue:1

    Topics: Actins; Animals; Anticholesteremic Agents; Blotting, Western; Carbon Tetrachloride Poisoning; Centra

2014