probucol has been researched along with Cerebrovascular Disorders in 3 studies
Probucol: A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
probucol : A dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high levels of cholesterol in blood.
Cerebrovascular Disorders: A spectrum of pathological conditions of impaired blood flow in the brain. They can involve vessels (ARTERIES or VEINS) in the CEREBRUM, the CEREBELLUM, and the BRAIN STEM. Major categories include INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; and others.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Probucol is a lipid-lowering agent with potent anti-oxidant properties once commonly used for the treatment of cardiovascular disease." | 1.39 | Probucol prevents blood-brain barrier dysfunction in wild-type mice induced by saturated fat or cholesterol feeding. ( Dhaliwal, SS; Galloway, S; Lam, V; Mamo, JC; Pallebage-Gamarallage, MM; Takechi, R, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Takechi, R | 1 |
| Galloway, S | 1 |
| Pallebage-Gamarallage, MM | 1 |
| Lam, V | 1 |
| Dhaliwal, SS | 1 |
| Mamo, JC | 1 |
| Kimura, Y | 1 |
| Uchiyama, S | 1 |
| Miettinen, TA | 1 |
| Huttunen, JK | 1 |
| Naukkarinen, V | 1 |
| Strandberg, T | 1 |
| Vanhanen, H | 1 |
1 review available for probucol and Cerebrovascular Disorders
| Article | Year |
|---|---|
[Hyperlipidemia and cerebrovascular disease].
Topics: Anticholesteremic Agents; Apolipoproteins; Cerebral Infarction; Cerebrovascular Disorders; Cholester | 2001 |
1 trial available for probucol and Cerebrovascular Disorders
| Article | Year |
|---|---|
Long-term use of probucol in the multifactorial primary prevention of vascular disease.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Cerebrovascular Disorders; Cholesterol, HDL; C | 1986 |
1 other study available for probucol and Cerebrovascular Disorders
| Article | Year |
|---|---|
Probucol prevents blood-brain barrier dysfunction in wild-type mice induced by saturated fat or cholesterol feeding.
Topics: Amyloid beta-Peptides; Animals; Apolipoproteins B; Blood-Brain Barrier; Cerebrovascular Disorders; C | 2013 |