probucol has been researched along with Cerebral Infarction in 4 studies
Probucol: A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
probucol : A dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high levels of cholesterol in blood.
Cerebral Infarction: The formation of an area of NECROSIS in the CEREBRUM caused by an insufficiency of arterial or venous blood flow. Infarcts of the cerebrum are generally classified by hemisphere (i.e., left vs. right), lobe (e.g., frontal lobe infarction), arterial distribution (e.g., INFARCTION, ANTERIOR CEREBRAL ARTERY), and etiology (e.g., embolic infarction).
| Excerpt | Relevance | Reference |
|---|---|---|
| "To observe the effects of combination of Lumbrukinase Capsule (LC) and Probucol Tablet (PT) in treating cerebral infarction (CI) patients' unstable atheromatous plaque of the carotid artery." | 9.15 | [Efficacy observation of combination of Lumbrukinase Capsule and Probucol Tablet in treating cerebral infarction patients' unstable atheromatous plaque of the carotid artery]. ( Chen, GH; Pan, XF; Shao, W, 2011) |
| "The family members had episodes of cerebral infarction and apparently had atherosclerosis of the internal carotid artery, but no coronary heart disease due to their almost normal level of cholesterol." | 5.28 | A family of familial hypercholesterolemia with cerebral infarction and without coronary heart disease. An unusual case with corneal opacity, polyneuropathy and carpal tunnel syndrome in the family: therapy with probucol and tocopherol nicotinate. ( Fujita, H; Ihara, Y; Kajinami, K; Kamisaka, K; Kibata, M; Mabuchi, H; Namba, R; Nobukuni, K; Ohshima, K; Shirabe, T, 1991) |
| "To observe the effects of combination of Lumbrukinase Capsule (LC) and Probucol Tablet (PT) in treating cerebral infarction (CI) patients' unstable atheromatous plaque of the carotid artery." | 5.15 | [Efficacy observation of combination of Lumbrukinase Capsule and Probucol Tablet in treating cerebral infarction patients' unstable atheromatous plaque of the carotid artery]. ( Chen, GH; Pan, XF; Shao, W, 2011) |
| "The family members had episodes of cerebral infarction and apparently had atherosclerosis of the internal carotid artery, but no coronary heart disease due to their almost normal level of cholesterol." | 1.28 | A family of familial hypercholesterolemia with cerebral infarction and without coronary heart disease. An unusual case with corneal opacity, polyneuropathy and carpal tunnel syndrome in the family: therapy with probucol and tocopherol nicotinate. ( Fujita, H; Ihara, Y; Kajinami, K; Kamisaka, K; Kibata, M; Mabuchi, H; Namba, R; Nobukuni, K; Ohshima, K; Shirabe, T, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pan, XF | 1 |
| Shao, W | 1 |
| Chen, GH | 1 |
| Park, SY | 1 |
| Lee, JH | 1 |
| Kim, CD | 1 |
| Rhim, BY | 1 |
| Hong, KW | 1 |
| Lee, WS | 1 |
| Kimura, Y | 1 |
| Uchiyama, S | 1 |
| Ihara, Y | 1 |
| Nobukuni, K | 1 |
| Namba, R | 1 |
| Kamisaka, K | 1 |
| Kibata, M | 1 |
| Kajinami, K | 1 |
| Fujita, H | 1 |
| Mabuchi, H | 1 |
| Shirabe, T | 1 |
| Ohshima, K | 1 |
1 review available for probucol and Cerebral Infarction
| Article | Year |
|---|---|
[Hyperlipidemia and cerebrovascular disease].
Topics: Anticholesteremic Agents; Apolipoproteins; Cerebral Infarction; Cerebrovascular Disorders; Cholester | 2001 |
1 trial available for probucol and Cerebral Infarction
| Article | Year |
|---|---|
[Efficacy observation of combination of Lumbrukinase Capsule and Probucol Tablet in treating cerebral infarction patients' unstable atheromatous plaque of the carotid artery].
Topics: Adult; Aged; Animals; Biological Products; Carotid Artery Diseases; Cerebral Infarction; Female; Hum | 2011 |
2 other studies available for probucol and Cerebral Infarction
| Article | Year |
|---|---|
Beneficial synergistic effects of concurrent treatment with cilostazol and probucol against focal cerebral ischemic injury in rats.
Topics: Animals; Antioxidants; Apoptosis; Biomarkers; Brain Ischemia; Caspase 3; Cerebral Infarction; Chemot | 2007 |
A family of familial hypercholesterolemia with cerebral infarction and without coronary heart disease. An unusual case with corneal opacity, polyneuropathy and carpal tunnel syndrome in the family: therapy with probucol and tocopherol nicotinate.
Topics: Arteriosclerosis; Axons; Carpal Tunnel Syndrome; CD4-CD8 Ratio; Cerebral Infarction; Corneal Opacity | 1991 |