probucol has been researched along with Cataract in 3 studies
Probucol: A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
probucol : A dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high levels of cholesterol in blood.
Cataract: Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We examined the effect of probucol, an antihyperlipidemic drug with potent antioxidant properties, on cataract formation in streptozotocin (STZ)-induced hyperglycemic rats that were given 5% D-glucose as drinking water." | 7.91 | Probucol Slows the Progression of Cataracts in Streptozotocin-Induced Hyperglycemic Rats. ( Higashi, K; Ishii, K; Mori, A; Nakahara, T; Sakamoto, K, 2019) |
| "We investigated the effects of long-term treatment with probucol, a hypolipidemic agent with antioxidative action, insulin, or their combination on cataracts of streptozotocin-induced diabetic rats fed a high cholesterol diet." | 7.73 | Combined effect of probucol and insulin on cataracts of diabetic rats fed a high cholesterol diet. ( Ito, M; Kimura, H; Kyuki, K; Yoshida, M, 2005) |
| "We examined the effect of probucol, an antihyperlipidemic drug with potent antioxidant properties, on cataract formation in streptozotocin (STZ)-induced hyperglycemic rats that were given 5% D-glucose as drinking water." | 3.91 | Probucol Slows the Progression of Cataracts in Streptozotocin-Induced Hyperglycemic Rats. ( Higashi, K; Ishii, K; Mori, A; Nakahara, T; Sakamoto, K, 2019) |
| "We investigated the effects of long-term treatment with probucol, a hypolipidemic agent with antioxidative action, insulin, or their combination on cataracts of streptozotocin-induced diabetic rats fed a high cholesterol diet." | 3.73 | Combined effect of probucol and insulin on cataracts of diabetic rats fed a high cholesterol diet. ( Ito, M; Kimura, H; Kyuki, K; Yoshida, M, 2005) |
| "Cataract formation occurred after 13 weeks in diabetic animals compared with 17 weeks for those treated with aminoguanidine, and 16 weeks for those treated with probucol (p < 0." | 3.70 | Effects of inhibition of glycation and oxidative stress on the development of cataract and retinal vessel abnormalities in diabetic rats. ( Agardh, C; Agardh, E; Hultberg, B, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Higashi, K | 1 |
| Mori, A | 1 |
| Sakamoto, K | 1 |
| Ishii, K | 1 |
| Nakahara, T | 1 |
| Yoshida, M | 1 |
| Kimura, H | 1 |
| Kyuki, K | 1 |
| Ito, M | 1 |
| Agardh, E | 1 |
| Hultberg, B | 1 |
| Agardh, C | 1 |
3 other studies available for probucol and Cataract
| Article | Year |
|---|---|
Probucol Slows the Progression of Cataracts in Streptozotocin-Induced Hyperglycemic Rats.
Topics: Animals; Antioxidants; Biomarkers; Blood Glucose; Cataract; Diabetes Mellitus, Experimental; Disease | 2019 |
Combined effect of probucol and insulin on cataracts of diabetic rats fed a high cholesterol diet.
Topics: Animals; Blood Glucose; Body Weight; Cataract; Cholesterol; Cholesterol, Dietary; Diabetes Mellitus, | 2005 |
Effects of inhibition of glycation and oxidative stress on the development of cataract and retinal vessel abnormalities in diabetic rats.
Topics: Animals; Blood Glucose; Body Weight; Cataract; Cysteine; Diabetes Mellitus, Experimental; Diabetic R | 2000 |