probucol has been researched along with Carotid Arteriopathies, Traumatic in 4 studies
Probucol: A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
probucol : A dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high levels of cholesterol in blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Probucol has recently been shown to reduce the incidence of post-angioplasty restenosis in a number of small clinical trials, making it possible to reassess the validity of the rat balloon injury model." | 1.31 | Effects of probucol on rat carotid artery responses to balloon catheter injury. ( Jackson, CL; Pettersson, KS, 2001) |
| "Probucol was given orally 1." | 1.30 | Effect of probucol on smooth muscle cell proliferation and dedifferentiation after vascular injury in rabbits: possible role of PDGF. ( Aikawa, M; Kawai, S; Miyauchi, K; Nagai, R; Nakahara, K; Okada, R; Tani, T; Yamaguchi, H, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ishizaka, N | 1 |
| Kurokawa, K | 1 |
| Taguchi, J | 1 |
| Miki, K | 1 |
| Ohno, M | 1 |
| Miyauchi, K | 1 |
| Aikawa, M | 1 |
| Tani, T | 1 |
| Nakahara, K | 1 |
| Kawai, S | 1 |
| Nagai, R | 1 |
| Okada, R | 1 |
| Yamaguchi, H | 1 |
| Jackson, CL | 1 |
| Pettersson, KS | 1 |
| Shinomiya, M | 1 |
| Shirai, K | 1 |
| Saito, Y | 1 |
| Yoshida, S | 1 |
4 other studies available for probucol and Carotid Arteriopathies, Traumatic
| Article | Year |
|---|---|
Inhibitory effect of a single local probucol administration on neointimal formation in balloon-injured rat carotid artery.
Topics: Administration, Topical; Animals; Anticholesteremic Agents; Carotid Artery Injuries; Carotid Artery, | 1995 |
Effect of probucol on smooth muscle cell proliferation and dedifferentiation after vascular injury in rabbits: possible role of PDGF.
Topics: Angioplasty, Balloon; Animals; Anticholesteremic Agents; Carotid Artery Injuries; Carotid Artery, Co | 1998 |
Effects of probucol on rat carotid artery responses to balloon catheter injury.
Topics: Administration, Oral; Angioplasty, Balloon; Animals; Anticholesteremic Agents; Apoptosis; Carotid Ar | 2001 |
Inhibition of intimal thickening of the carotid artery of rabbits and of outgrowth of explants of aorta by probucol.
Topics: Animals; Aorta; Carotid Arteries; Carotid Artery Injuries; Catheterization; Cell Division; Cell Move | 1992 |