probucol has been researched along with Cardiac Remodeling, Ventricular in 3 studies
Probucol: A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
probucol : A dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high levels of cholesterol in blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We examined whether antioxidant and antiinflammatory treatment with probucol decreases myocardial oxidative stress and inflammation and attenuates the progression of left ventricular (LV) dysfunction and remodeling (dilatation) in tachycardia-induced HF." | 7.71 | Probucol attenuates left ventricular dysfunction and remodeling in tachycardia-induced heart failure: roles of oxidative stress and inflammation. ( Egashira, K; Hayashidani, S; Machida, Y; Nakamura, R; Takeshita, A; Takeya, M; Tsutsui, H; Utsumi, H, 2002) |
| " We examined whether antioxidant and antiinflammatory treatment with probucol decreases myocardial oxidative stress and inflammation and attenuates the progression of left ventricular (LV) dysfunction and remodeling (dilatation) in tachycardia-induced HF." | 3.71 | Probucol attenuates left ventricular dysfunction and remodeling in tachycardia-induced heart failure: roles of oxidative stress and inflammation. ( Egashira, K; Hayashidani, S; Machida, Y; Nakamura, R; Takeshita, A; Takeya, M; Tsutsui, H; Utsumi, H, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nakamura, R | 1 |
| Egashira, K | 1 |
| Machida, Y | 1 |
| Hayashidani, S | 1 |
| Takeya, M | 1 |
| Utsumi, H | 1 |
| Tsutsui, H | 1 |
| Takeshita, A | 1 |
| Betge, S | 1 |
| Lutz, K | 1 |
| Roskos, M | 1 |
| Figulla, HR | 1 |
| Sia, YT | 1 |
| Lapointe, N | 1 |
| Parker, TG | 1 |
| Tsoporis, JN | 1 |
| Deschepper, CF | 1 |
| Calderone, A | 1 |
| Pourdjabbar, A | 1 |
| Jasmin, JF | 1 |
| Sarrazin, JF | 1 |
| Liu, P | 1 |
| Adam, A | 1 |
| Butany, J | 1 |
| Rouleau, JL | 1 |
3 other studies available for probucol and Cardiac Remodeling, Ventricular
| Article | Year |
|---|---|
Probucol attenuates left ventricular dysfunction and remodeling in tachycardia-induced heart failure: roles of oxidative stress and inflammation.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cardiac Pacing, Artificial; Cardiomyopathy, Dilated | 2002 |
Oral treatment with probucol in a pharmacological dose has no beneficial effects on mortality in chronic ischemic heart failure after large myocardial infarction in rats.
Topics: Administration, Oral; Animals; Antioxidants; Chronic Disease; Collagen; Heart Failure; Male; Myocard | 2007 |
Beneficial effects of long-term use of the antioxidant probucol in heart failure in the rat.
Topics: Animals; Antioxidants; Apoptosis; Atrial Natriuretic Factor; Chronic Disease; Disease Models, Animal | 2002 |