Page last updated: 2024-11-03

probucol and Brain Vascular Disorders

probucol has been researched along with Brain Vascular Disorders in 3 studies

Probucol: A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
probucol : A dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high levels of cholesterol in blood.

Research Excerpts

ExcerptRelevanceReference
"Probucol is a lipid-lowering agent with potent anti-oxidant properties once commonly used for the treatment of cardiovascular disease."1.39Probucol prevents blood-brain barrier dysfunction in wild-type mice induced by saturated fat or cholesterol feeding. ( Dhaliwal, SS; Galloway, S; Lam, V; Mamo, JC; Pallebage-Gamarallage, MM; Takechi, R, 2013)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Takechi, R1
Galloway, S1
Pallebage-Gamarallage, MM1
Lam, V1
Dhaliwal, SS1
Mamo, JC1
Kimura, Y1
Uchiyama, S1
Miettinen, TA1
Huttunen, JK1
Naukkarinen, V1
Strandberg, T1
Vanhanen, H1

Reviews

1 review available for probucol and Brain Vascular Disorders

ArticleYear
[Hyperlipidemia and cerebrovascular disease].
    Nihon rinsho. Japanese journal of clinical medicine, 2001, Volume: 59 Suppl 2

    Topics: Anticholesteremic Agents; Apolipoproteins; Cerebral Infarction; Cerebrovascular Disorders; Cholester

2001

Trials

1 trial available for probucol and Brain Vascular Disorders

ArticleYear
Long-term use of probucol in the multifactorial primary prevention of vascular disease.
    The American journal of cardiology, 1986, Jun-27, Volume: 57, Issue:16

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Cerebrovascular Disorders; Cholesterol, HDL; C

1986

Other Studies

1 other study available for probucol and Brain Vascular Disorders

ArticleYear
Probucol prevents blood-brain barrier dysfunction in wild-type mice induced by saturated fat or cholesterol feeding.
    Clinical and experimental pharmacology & physiology, 2013, Volume: 40, Issue:1

    Topics: Amyloid beta-Peptides; Animals; Apolipoproteins B; Blood-Brain Barrier; Cerebrovascular Disorders; C

2013