probucol has been researched along with Auricular Fibrillation in 9 studies
Probucol: A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
probucol : A dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high levels of cholesterol in blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| " However, the underlying mechanisms for the increased propensity for AF in the setting of DM and the potential effects of probucol on atrial remodeling remain unclear." | 7.81 | Probucol prevents atrial remodeling by inhibiting oxidative stress and TNF-α/NF-κB/TGF-β signal transduction pathway in alloxan-induced diabetic rabbits. ( Cheng, L; Fu, H; Li, G; Li, J; Liu, C; Liu, T; Wang, X, 2015) |
| "We report a patient who experienced a reversible prolongation of the QT interval and episodes of syncope while receiving probucol." | 7.69 | Probucol-induced QT prolongation and syncope. ( Ito, M; Ohtsuka, E; Oribe, K; Oribe, M; Seita, M; Tamura, M; Ueki, Y, 1994) |
| "Probucol decreased the increase of CRP concentration and attenuated atrial oxidative stress caused by atrial tachypacing." | 5.35 | Probucol attenuates atrial autonomic remodeling in a canine model of atrial fibrillation produced by prolonged atrial pacing. ( Dong, DL; Gong, YT; Li, BX; Li, WM; Li, Y; Liu, W; Shan, HB; Sheng, L; Xue, HJ; Yang, BF; Yang, N; Yang, SS, 2009) |
| " However, the underlying mechanisms for the increased propensity for AF in the setting of DM and the potential effects of probucol on atrial remodeling remain unclear." | 3.81 | Probucol prevents atrial remodeling by inhibiting oxidative stress and TNF-α/NF-κB/TGF-β signal transduction pathway in alloxan-induced diabetic rabbits. ( Cheng, L; Fu, H; Li, G; Li, J; Liu, C; Liu, T; Wang, X, 2015) |
| "We report a patient who experienced a reversible prolongation of the QT interval and episodes of syncope while receiving probucol." | 3.69 | Probucol-induced QT prolongation and syncope. ( Ito, M; Ohtsuka, E; Oribe, K; Oribe, M; Seita, M; Tamura, M; Ueki, Y, 1994) |
| "Probucol decreased the increase of CRP concentration and attenuated atrial oxidative stress caused by atrial tachypacing." | 1.35 | Probucol attenuates atrial autonomic remodeling in a canine model of atrial fibrillation produced by prolonged atrial pacing. ( Dong, DL; Gong, YT; Li, BX; Li, WM; Li, Y; Liu, W; Shan, HB; Sheng, L; Xue, HJ; Yang, BF; Yang, N; Yang, SS, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 6 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, Q | 1 |
| Liu, T | 5 |
| Ng, CY | 1 |
| Li, G | 5 |
| Fu, H | 3 |
| Liu, C | 2 |
| Li, J | 2 |
| Wang, X | 1 |
| Cheng, L | 2 |
| Ziolo, MT | 1 |
| Mohler, PJ | 1 |
| Shao, Q | 1 |
| Korantzopoulos, P | 1 |
| Ye, L | 1 |
| Liu, E | 1 |
| Xu, G | 1 |
| Yang, W | 1 |
| Tse, G | 1 |
| Zhao, J | 1 |
| Gong, YT | 1 |
| Li, WM | 1 |
| Li, Y | 2 |
| Yang, SS | 1 |
| Sheng, L | 2 |
| Yang, N | 1 |
| Shan, HB | 1 |
| Xue, HJ | 1 |
| Liu, W | 2 |
| Yang, BF | 1 |
| Dong, DL | 1 |
| Li, BX | 1 |
| Li, W | 1 |
| Gong, Y | 1 |
| Xue, H | 1 |
| Shan, H | 1 |
| Tamura, M | 1 |
| Ueki, Y | 1 |
| Ohtsuka, E | 1 |
| Oribe, M | 1 |
| Seita, M | 1 |
| Oribe, K | 1 |
| Ito, M | 1 |
1 review available for probucol and Auricular Fibrillation
| Article | Year |
|---|---|
Diabetes mellitus and atrial remodeling: mechanisms and potential upstream therapies.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Atrial Fibrillation; Atr | 2014 |
1 trial available for probucol and Auricular Fibrillation
| Article | Year |
|---|---|
Effects of probucol on left atrial remodeling in patients with paroxysmal atrial fibrillation.
Topics: Aged; Anticholesteremic Agents; Atrial Fibrillation; Atrial Remodeling; Female; Follow-Up Studies; H | 2016 |
7 other studies available for probucol and Auricular Fibrillation
| Article | Year |
|---|---|
Probucol prevents atrial remodeling by inhibiting oxidative stress and TNF-α/NF-κB/TGF-β signal transduction pathway in alloxan-induced diabetic rabbits.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Atrial Fibrillation; Atrial Remodeling; Biomarkers; | 2015 |
Defining the role of oxidative stress in atrial fibrillation and diabetes.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Atrial Fibrillation; Atrial Remodeling; Diabetes Me | 2015 |
Probucol prevents atrial ion channel remodeling in an alloxan-induced diabetes rabbit model.
Topics: Action Potentials; Alloxan; Animals; Anti-Arrhythmia Agents; Antioxidants; Atrial Fibrillation; Atri | 2016 |
Probucol attenuates atrial autonomic remodeling in a canine model of atrial fibrillation produced by prolonged atrial pacing.
Topics: Animals; Antioxidants; Atrial Fibrillation; Blotting, Western; C-Reactive Protein; Cardiac Pacing, A | 2009 |
Probucol and succinobucol in atrial fibrillation: pros and cons.
Topics: Anticholesteremic Agents; Atrial Fibrillation; Humans; Probucol | 2010 |
Probucol attenuates atrial structural remodeling in prolonged pacing-induced atrial fibrillation in dogs.
Topics: Animals; Antioxidants; Apoptosis; Atrial Fibrillation; bcl-2-Associated X Protein; Calpain; Caspase | 2009 |
Probucol-induced QT prolongation and syncope.
Topics: Atrial Fibrillation; Diltiazem; Electrocardiography; Female; Humans; Hypercholesterolemia; Long QT S | 1994 |