probucol has been researched along with Atheroma in 7 studies
Probucol: A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
probucol : A dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high levels of cholesterol in blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To observe the effects of combination of Lumbrukinase Capsule (LC) and Probucol Tablet (PT) in treating cerebral infarction (CI) patients' unstable atheromatous plaque of the carotid artery." | 9.15 | [Efficacy observation of combination of Lumbrukinase Capsule and Probucol Tablet in treating cerebral infarction patients' unstable atheromatous plaque of the carotid artery]. ( Chen, GH; Pan, XF; Shao, W, 2011) |
| "We have investigated the possible effects and mechanism of atorvastatin, a statin, and/or probucol, a powerful antioxidant used to lower cholesterol before 1995, on the atherosclerosis development." | 7.91 | Effects of atorvastatin and/or probucol on recovery of atherosclerosis in high-fat-diet-fed apolipoprotein E-deficient mice. ( Guo, X; Li, X; Wang, L; Wang, P; Xia, X, 2019) |
| "Activation of Na(+)/H(+) exchanger 1 (NHE1) by lipopolysaccharide (LPS) via Ca(2+)/calpain is responsible in vascular smooth muscle cell (VSMC) apoptosis and to the process of atherosclerosis." | 7.80 | Probucol via inhibition of NHE1 attenuates LPS-accelerated atherosclerosis and promotes plaque stability in vivo. ( Chen, S; Feng, JD; Li, JF; Liu, XX; Zhang, MY, 2014) |
| "Probucol and statin are often prescribed for treating atherosclerosis." | 7.79 | Probucol inhibits the initiation of atherosclerosis in cholesterol-fed rabbits. ( Fan, J; Keyamura, Y; Kohashi, M; Koyama, T; Niimi, M; Nozako, M; Yasufuku, R; Yoshikawa, T, 2013) |
| "To observe the effects of combination of Lumbrukinase Capsule (LC) and Probucol Tablet (PT) in treating cerebral infarction (CI) patients' unstable atheromatous plaque of the carotid artery." | 5.15 | [Efficacy observation of combination of Lumbrukinase Capsule and Probucol Tablet in treating cerebral infarction patients' unstable atheromatous plaque of the carotid artery]. ( Chen, GH; Pan, XF; Shao, W, 2011) |
| "We have investigated the possible effects and mechanism of atorvastatin, a statin, and/or probucol, a powerful antioxidant used to lower cholesterol before 1995, on the atherosclerosis development." | 3.91 | Effects of atorvastatin and/or probucol on recovery of atherosclerosis in high-fat-diet-fed apolipoprotein E-deficient mice. ( Guo, X; Li, X; Wang, L; Wang, P; Xia, X, 2019) |
| "Activation of Na(+)/H(+) exchanger 1 (NHE1) by lipopolysaccharide (LPS) via Ca(2+)/calpain is responsible in vascular smooth muscle cell (VSMC) apoptosis and to the process of atherosclerosis." | 3.80 | Probucol via inhibition of NHE1 attenuates LPS-accelerated atherosclerosis and promotes plaque stability in vivo. ( Chen, S; Feng, JD; Li, JF; Liu, XX; Zhang, MY, 2014) |
| "Probucol and statin are often prescribed for treating atherosclerosis." | 3.79 | Probucol inhibits the initiation of atherosclerosis in cholesterol-fed rabbits. ( Fan, J; Keyamura, Y; Kohashi, M; Koyama, T; Niimi, M; Nozako, M; Yasufuku, R; Yoshikawa, T, 2013) |
| "Probucol is a lipid-lowering drug that is often prescribed for the treatment of familial hypercholesterolemia." | 1.40 | Probucol suppresses macrophage infiltration and MMP expression in atherosclerotic plaques of WHHL rabbits. ( Bilal Waqar, A; Fan, J; Kang, D; Koike, T; Li, S; Liang, J; Niimi, M; Shiomi, M; Wang, Y, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guo, X | 1 |
| Wang, L | 1 |
| Xia, X | 1 |
| Wang, P | 1 |
| Li, X | 1 |
| Niimi, M | 2 |
| Keyamura, Y | 1 |
| Nozako, M | 1 |
| Koyama, T | 1 |
| Kohashi, M | 1 |
| Yasufuku, R | 1 |
| Yoshikawa, T | 1 |
| Fan, J | 2 |
| Li, S | 1 |
| Liang, J | 1 |
| Bilal Waqar, A | 1 |
| Kang, D | 1 |
| Koike, T | 1 |
| Wang, Y | 1 |
| Shiomi, M | 1 |
| Li, JF | 1 |
| Chen, S | 1 |
| Feng, JD | 1 |
| Zhang, MY | 1 |
| Liu, XX | 1 |
| Yakushiji, E | 1 |
| Ayaori, M | 1 |
| Nishida, T | 1 |
| Shiotani, K | 1 |
| Takiguchi, S | 1 |
| Nakaya, K | 1 |
| Uto-Kondo, H | 1 |
| Ogura, M | 1 |
| Sasaki, M | 1 |
| Yogo, M | 1 |
| Komatsu, T | 1 |
| Lu, R | 1 |
| Yokoyama, S | 1 |
| Ikewaki, K | 1 |
| Li, T | 1 |
| Chen, W | 1 |
| An, F | 1 |
| Tian, H | 1 |
| Zhang, J | 1 |
| Peng, J | 1 |
| Zhang, Y | 1 |
| Guo, Y | 1 |
| Pan, XF | 1 |
| Shao, W | 1 |
| Chen, GH | 1 |
1 trial available for probucol and Atheroma
| Article | Year |
|---|---|
[Efficacy observation of combination of Lumbrukinase Capsule and Probucol Tablet in treating cerebral infarction patients' unstable atheromatous plaque of the carotid artery].
Topics: Adult; Aged; Animals; Biological Products; Carotid Artery Diseases; Cerebral Infarction; Female; Hum | 2011 |
6 other studies available for probucol and Atheroma
| Article | Year |
|---|---|
Effects of atorvastatin and/or probucol on recovery of atherosclerosis in high-fat-diet-fed apolipoprotein E-deficient mice.
Topics: Animals; Antioxidants; Apolipoproteins E; Atherosclerosis; Atorvastatin; Cholesterol; Cytokines; Die | 2019 |
Probucol inhibits the initiation of atherosclerosis in cholesterol-fed rabbits.
Topics: Animals; Anticholesteremic Agents; Aorta; Atherosclerosis; Atorvastatin; Cell Adhesion; Cholesterol; | 2013 |
Probucol suppresses macrophage infiltration and MMP expression in atherosclerotic plaques of WHHL rabbits.
Topics: Animals; Anticholesteremic Agents; Atorvastatin; Cells, Cultured; Disease Models, Animal; Heptanoic | 2014 |
Probucol via inhibition of NHE1 attenuates LPS-accelerated atherosclerosis and promotes plaque stability in vivo.
Topics: Animals; Atherosclerosis; Calcium; Calpain; Cation Transport Proteins; Humans; Lipopolysaccharides; | 2014 |
Probucol-Oxidized Products, Spiroquinone and Diphenoquinone, Promote Reverse Cholesterol Transport in Mice.
Topics: Androstadienes; Animals; Anticholesteremic Agents; Aorta; Aortic Diseases; Apolipoprotein A-I; Apoli | 2016 |
Probucol attenuates inflammation and increases stability of vulnerable atherosclerotic plaques in rabbits.
Topics: Animals; Aorta, Abdominal; Biomarkers; Chemokine CCL2; Enzyme-Linked Immunosorbent Assay; Gene Expre | 2011 |