Page last updated: 2024-11-03

probucol and Aortic Aneurysm, Abdominal

probucol has been researched along with Aortic Aneurysm, Abdominal in 1 studies

Probucol: A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
probucol : A dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high levels of cholesterol in blood.

Aortic Aneurysm, Abdominal: An abnormal balloon- or sac-like dilatation in the wall of the ABDOMINAL AORTA which gives rise to the visceral, the parietal, and the terminal (iliac) branches below the aortic hiatus at the diaphragm.

Research Excerpts

ExcerptRelevanceReference
"Probucol has been widely applied to treat hyperlipidaemia and atherosclerosis in clinic, but whether it can protect against AAA remains unknown."5.56Mechanisms underlying the inhibitory effects of probucol on elastase-induced abdominal aortic aneurysm in mice. ( Anwaier, G; Cao, Y; Chen, C; Qi, R; Wang, Q; Wang, Y; Zhang, Q, 2020)
"Probucol has been widely applied to treat hyperlipidaemia and atherosclerosis in clinic, but whether it can protect against AAA remains unknown."1.56Mechanisms underlying the inhibitory effects of probucol on elastase-induced abdominal aortic aneurysm in mice. ( Anwaier, G; Cao, Y; Chen, C; Qi, R; Wang, Q; Wang, Y; Zhang, Q, 2020)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Chen, C1
Wang, Y1
Cao, Y1
Wang, Q1
Anwaier, G1
Zhang, Q1
Qi, R1

Other Studies

1 other study available for probucol and Aortic Aneurysm, Abdominal

ArticleYear
Mechanisms underlying the inhibitory effects of probucol on elastase-induced abdominal aortic aneurysm in mice.
    British journal of pharmacology, 2020, Volume: 177, Issue:1

    Topics: Animals; Anticholesteremic Agents; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Cells, Cultured; He

2020