probucol has been researched along with Anti-Phospholipid Antibody Syndrome in 1 studies
Probucol: A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
probucol : A dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high levels of cholesterol in blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The pathogenesis of antiphospholipid antibody (aPL) related thrombosis is multifactorial and includes, amongst others, enhanced coagulation activation measured as prothrombin fragment 1 + 2 (F1 + 2), elevated plasma levels of von Willebrand factor (vWF), plasminogen activator inhibitor (PAI) and endothelin-1 (ET-1) as well as heightened thromboxane generation and lipid peroxidation." | 5.09 | Antioxidant susceptibility of pathogenic pathways in subjects with antiphospholipid antibodies: a pilot study. ( Alves, J; Ames, PR; Brancaccio, V; Caccavo, F; Caruso, S; Fossati, G; Iannaccone, L; Morrow, JD; Tommasino, C, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ames, PR | 1 |
| Tommasino, C | 1 |
| Alves, J | 1 |
| Morrow, JD | 1 |
| Iannaccone, L | 1 |
| Fossati, G | 1 |
| Caruso, S | 1 |
| Caccavo, F | 1 |
| Brancaccio, V | 1 |
1 trial available for probucol and Anti-Phospholipid Antibody Syndrome
| Article | Year |
|---|---|
Antioxidant susceptibility of pathogenic pathways in subjects with antiphospholipid antibodies: a pilot study.
Topics: Adult; Albuminuria; Antibodies, Antiphospholipid; Anticholesteremic Agents; Anticoagulants; Antioxid | 2000 |