probucol has been researched along with Acute Disease in 4 studies
Probucol: A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
probucol : A dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high levels of cholesterol in blood.
Acute Disease: Disease having a short and relatively severe course.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of the present study was to develop a model of hypertriglyceridemic (HTG) acute pancreatitis and to investigate the effects of probucol in this model." | 7.78 | Development of a novel model of hypertriglyceridemic acute pancreatitis in hamsters: protective effects of probucol. ( Cui, X; Guo, C; Hu, G; Li, H; Liu, G; Liu, L; Liu, Y; Shen, J; Tang, Y; Wang, X; Wang, Y; Yu, Y; Zhao, Y, 2012) |
| "High-fat pancreatitis and hyperlipidemia refer to disorders of blood lipid metabolism caused by abnormally elevated blood lipids, and are risk factors for high-risk diseases such as atherosclerosis, coronary heart disease, and cerebral infarction." | 5.62 | Study on the Mechanism of Probucol Nanosuspension on Hyperlipidemic Pancreatitis and Regulation of Blood Lipid Function. ( Jiang, X; Wang, X; Wu, Z, 2021) |
| "The aim of the present study was to develop a model of hypertriglyceridemic (HTG) acute pancreatitis and to investigate the effects of probucol in this model." | 3.78 | Development of a novel model of hypertriglyceridemic acute pancreatitis in hamsters: protective effects of probucol. ( Cui, X; Guo, C; Hu, G; Li, H; Liu, G; Liu, L; Liu, Y; Shen, J; Tang, Y; Wang, X; Wang, Y; Yu, Y; Zhao, Y, 2012) |
| "We investigated the effect of probucol, a lipid-lowering agent with antioxidant properties, on HCl plus ethanol-induced gastric mucosal injury and on the healing of acetic acid-induced gastric ulcers in rats." | 3.70 | Anti-ulcer effects of antioxidants: effect of probucol. ( Ishihara, M; Ito, M; Suzuki, Y, 1998) |
| "High-fat pancreatitis and hyperlipidemia refer to disorders of blood lipid metabolism caused by abnormally elevated blood lipids, and are risk factors for high-risk diseases such as atherosclerosis, coronary heart disease, and cerebral infarction." | 1.62 | Study on the Mechanism of Probucol Nanosuspension on Hyperlipidemic Pancreatitis and Regulation of Blood Lipid Function. ( Jiang, X; Wang, X; Wu, Z, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, Z | 1 |
| Wang, X | 2 |
| Jiang, X | 1 |
| Hu, G | 1 |
| Zhao, Y | 1 |
| Tang, Y | 1 |
| Wang, Y | 1 |
| Shen, J | 1 |
| Liu, L | 1 |
| Li, H | 1 |
| Liu, Y | 1 |
| Cui, X | 1 |
| Yu, Y | 1 |
| Guo, C | 1 |
| Liu, G | 1 |
| Ito, M | 1 |
| Suzuki, Y | 2 |
| Ishihara, M | 1 |
| Kanaki, T | 1 |
| Saito, Y | 1 |
1 review available for probucol and Acute Disease
| Article | Year |
|---|---|
[Anti-atherogenic drugs].
Topics: Acute Disease; Angioplasty, Balloon, Coronary; Anticholesteremic Agents; Bezafibrate; Coronary Disea | 1998 |
3 other studies available for probucol and Acute Disease
| Article | Year |
|---|---|
Study on the Mechanism of Probucol Nanosuspension on Hyperlipidemic Pancreatitis and Regulation of Blood Lipid Function.
Topics: Acute Disease; Humans; Hyperlipidemias; Lipids; Pancreatitis; Probucol | 2021 |
Development of a novel model of hypertriglyceridemic acute pancreatitis in hamsters: protective effects of probucol.
Topics: Acute Disease; Amylases; Animals; Antioxidants; Biomarkers; Ceruletide; Cricetinae; Diet, High-Fat; | 2012 |
Anti-ulcer effects of antioxidants: effect of probucol.
Topics: Acetic Acid; Acute Disease; Animals; Anti-Ulcer Agents; Antioxidants; Chronic Disease; Cimetidine; D | 1998 |