probenecid has been researched along with Staphylococcal Infections in 22 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Staphylococcal Infections: Infections with bacteria of the genus STAPHYLOCOCCUS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The therapeutic efficacy of decloxacillin or flucloxacillin, 1--2 g orally with probenecid twice daily was evaluated in staphylococcal infections." | 7.66 | Dicloxacillin and flucloxacillin twice daily with probenecid in staphylococcal infections. A clinical and pharmakokinetic evaluation. ( Hedström, SA; Kahlmeter, G, 1980) |
| "The therapeutic efficacy of decloxacillin or flucloxacillin, 1--2 g orally with probenecid twice daily was evaluated in staphylococcal infections." | 3.66 | Dicloxacillin and flucloxacillin twice daily with probenecid in staphylococcal infections. A clinical and pharmakokinetic evaluation. ( Hedström, SA; Kahlmeter, G, 1980) |
| "Reduction in the dosage of dicloxacillin from 500 mg to 250 mg 3 times a day would mean lowering of costs and less side-effects in orthopaedic infections." | 2.67 | Should probenecid be used to reduce the dicloxacillin dosage in orthopaedic infections? A study of the dicloxacillin-saving effect of probenecid. ( Hansen, BA; Jensen, P; Krogsgaard, MR; Slotsbjerg, T, 1994) |
| "We treated septic arthritis of the knee in 38 rabbits with cloxacillin i." | 1.28 | Antibiotic treatment insufficient for established septic arthritis. Staphylococcus aureus experiments in rabbits. ( Frimodt-Møller, N; Jensen, JS; Riegels-Nielsen, P; Sørensen, M, 1989) |
| "Extraneous infective endocarditis is most often caused by staphylococci, with Gram-negative bacilli and fungi also quite frequent infecting agents." | 1.25 | The choice of antibiotic for treating infective endocarditis. ( Gray, IR, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (90.91) | 18.7374 |
| 1990's | 2 (9.09) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| KOENIG, MG | 1 |
| ABU-NASSAR, HJ | 1 |
| YOW, EM | 1 |
| ALEXANDER, JK | 1 |
| LEWIS, JM | 1 |
| KLEIN, JO | 1 |
| EICKHOFF, TC | 1 |
| TILLES, JG | 1 |
| FINLAND, M | 1 |
| PLATTNER, HC | 1 |
| SCHERER, J | 1 |
| Records, RE | 1 |
| Barza, M | 1 |
| Kane, A | 1 |
| Baum, J | 1 |
| Szaff, M | 1 |
| Høiby, N | 1 |
| Hedström, SA | 2 |
| Kahlmeter, G | 1 |
| Chayakul, P | 1 |
| Yipintsoi, T | 1 |
| Krogsgaard, MR | 1 |
| Hansen, BA | 1 |
| Slotsbjerg, T | 1 |
| Jensen, P | 1 |
| Gray, IR | 1 |
| Riegels-Nielsen, P | 1 |
| Frimodt-Møller, N | 1 |
| Sørensen, M | 1 |
| Jensen, JS | 1 |
| Tattersall, MH | 1 |
| Spiers, AS | 1 |
| Darrell, JH | 1 |
| Sevitt, S | 1 |
| Stone, P | 1 |
| Jackson, D | 1 |
| Baar, S | 1 |
| Pollock, A | 1 |
| Bell, SM | 1 |
| Ericson, C | 1 |
| Lidgren, L | 1 |
| Lindberg, L | 1 |
| Bartel, J | 1 |
| Legler, F | 1 |
| Maurer, LH | 1 |
| Schneider, TJ | 1 |
| Stammberger, K | 1 |
| Fiehring, H | 1 |
| Heimer, I | 1 |
| Sprössig, M | 1 |
| Hartman, RE | 1 |
| Carleton, J | 1 |
| Lustberg, A | 1 |
| Hamburger, M | 1 |
1 review available for probenecid and Staphylococcal Infections
| Article | Year |
|---|---|
THE TREATMENT OF STAPHYLOCOCCAL INFECTIONS.
Topics: Animals; Anti-Bacterial Agents; Antitoxins; Bacitracin; Carrier State; Erythromycin; Furunculosis; H | 1963 |
3 trials available for probenecid and Staphylococcal Infections
| Article | Year |
|---|---|
Should probenecid be used to reduce the dicloxacillin dosage in orthopaedic infections? A study of the dicloxacillin-saving effect of probenecid.
Topics: Administration, Oral; Biological Availability; Dicloxacillin; Drug Therapy, Combination; Humans; Ort | 1994 |
Cloxacillin in the prophylaxis of postoperative infections of the hip.
Topics: Aged; Bone Nails; Bone Plates; Cloxacillin; Double-Blind Method; Female; Follow-Up Studies; Hip Frac | 1973 |
Gonococcal urethritis in males in Vietnam: three penicillin regimens and one tetracycline regimen.
Topics: Bacteriological Techniques; Gonorrhea; Humans; Male; Military Medicine; Neisseria gonorrhoeae; Penic | 1969 |
18 other studies available for probenecid and Staphylococcal Infections
| Article | Year |
|---|---|
PRIMARY STAPHYLOCOCCAL PERICARDITIS COMPLICATING CARDIOTOMY: A REPORT OF A CASE WITH A NOTE ON INTRAPERICARDIAL METHICILLIN THERAPY.
Topics: Aspirin; Bacterial Infections; Cardiac Surgical Procedures; Methicillin; Penicillins; Pericarditis; | 1964 |
CEPHALOTHIN: ACTIVITY IN VITRO, ABSORPTION AND EXCRETION IN NORMAL SUBJECTS AND CLINICAL OBSERVATIONS IN 40 PATIENTS.
Topics: Absorption; Anti-Bacterial Agents; Biomedical Research; Blood; Cephalothin; Chemical Phenomena; Chem | 1964 |
[PRESENT STATUS OF THE TREATMENT OF STAPHYLOCOCCAL DISEASES].
Topics: Anti-Bacterial Agents; Cross Infection; Drug Therapy; Humans; Methicillin; Oxacillin; Penicillin G; | 1965 |
Human intraocular penetration of sodium oxacillin.
Topics: Aqueous Humor; Biological Assay; Biological Transport; Cataract Extraction; Eye Diseases; Humans; In | 1967 |
The effects of infection and probenecid on the transport of carbenicillin from the rabbit vitreous humor.
Topics: Animals; Aqueous Humor; Carbenicillin; Choroid; Cornea; Half-Life; Panophthalmitis; Probenecid; Rabb | 1982 |
Antibiotic treatment of Staphylococcus aureus infection in cystic fibrosis.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Child; Child, Preschool; Cystic Fibrosis; Dicloxacillin; F | 1982 |
Dicloxacillin and flucloxacillin twice daily with probenecid in staphylococcal infections. A clinical and pharmakokinetic evaluation.
Topics: Cloxacillin; Dicloxacillin; Drug Combinations; Drug Evaluation; Drug Therapy, Combination; Floxacill | 1980 |
Intravenous followed by oral antimicrobial therapy for staphylococcal endocarditis.
Topics: Administration, Oral; Adult; Aged; Cloxacillin; Dicloxacillin; Drug Administration Schedule; Drug Th | 1993 |
The choice of antibiotic for treating infective endocarditis.
Topics: Adolescent; Adult; Aged; Amoxicillin; Amphotericin B; Aneurysm, Infected; Anti-Bacterial Agents; Bac | 1975 |
Antibiotic treatment insufficient for established septic arthritis. Staphylococcus aureus experiments in rabbits.
Topics: Animals; Arthritis, Infectious; Cloxacillin; Drug Therapy, Combination; Knee Joint; Probenecid; Rabb | 1989 |
Initial therapy with combination of five antibiotics in febrile patients with leukaemia and neutropenia.
Topics: Administration, Oral; Agranulocytosis; Anemia, Aplastic; Anti-Bacterial Agents; Bacterial Infections | 1972 |
Acute Heinz-body anaemia in burned patients.
Topics: Adult; Ampicillin; Anemia, Hemolytic; Aspirin; Burns; Carbenicillin; Cloxacillin; Digoxin; Erythrocy | 1973 |
Oral penicillins in the treatment of chronic staphylococcal osteomyelitis.
Topics: Adolescent; Adult; Child; Cloxacillin; Female; Humans; Male; Middle Aged; Osteomyelitis; Penicillin | 1968 |
[Bacterial heart infections in the child--their relation to sepsis].
Topics: Anti-Bacterial Agents; Child; Child, Preschool; Electrocardiography; Endocarditis, Bacterial; Heart | 1974 |
[The role of ampicillin in antibiotic therapy with special reference to laboratory findings].
Topics: Ampicillin; Biliary Tract Diseases; Escherichia coli Infections; Humans; Klebsiella Infections; Meni | 1966 |
General and local antibiotic treatment of chronic osteomyelitis.
Topics: Administration, Oral; Adolescent; Adult; Aged; Blood Sedimentation; C-Reactive Protein; Child; Chlor | 1969 |
[Clinical-microbiological analysis of 50 patients with bacterial carditis].
Topics: Anti-Bacterial Agents; Endocarditis, Bacterial; Female; Glucocorticoids; Humans; Probenecid; Prognos | 1970 |
Effect of dicloxacillin, oxacillin, and nafcillin upon staphylococcal population and rate of healing of soft-tissue lesions.
Topics: Cloxacillin; Dicloxacillin; Humans; Nafcillin; Oxacillin; Penicillins; Probenecid; Staphylococcal In | 1966 |