probenecid has been researched along with Spinal Cord Injuries in 3 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Spinal Cord Injuries: Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Probenecid was well-tolerated by all subjects." | 2.87 | Oral probenecid improves sperm motility in men with spinal cord injury. ( Aballa, TC; Brackett, NL; Ibrahim, E; Lynne, CM, 2018) |
| "Oral treatment with probenecid - 500 mg per day for one week, then 500 mg twice daily [1000 mg total] per day for three weeks." | 1.62 | Proteomic insight of seminal plasma in spinal cord injured men submitted to oral probenecid treatment for improved motility. ( Aballa, TC; Bertolla, RP; Brackett, NL; Camargo, M; Cardozo, KHM; Carvalho, VM; Ibrahim, E; Lynne, CM, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Camargo, M | 1 |
| Ibrahim, E | 2 |
| Aballa, TC | 2 |
| Cardozo, KHM | 1 |
| Carvalho, VM | 1 |
| Lynne, CM | 2 |
| Brackett, NL | 2 |
| Bertolla, RP | 1 |
| Garelis, E | 1 |
| Young, SN | 1 |
| Lal, S | 1 |
| Sourkes, TL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Miami Project Male Fertility Program[NCT01467869] | 100 participants (Anticipated) | Observational | 1991-01-31 | Recruiting | |||
| Improvement of Reproductive Function in Men With Spinal Cord Injury (SCI)[NCT05903859] | Phase 3 | 90 participants (Anticipated) | Interventional | 2024-01-01 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for probenecid and Spinal Cord Injuries
| Article | Year |
|---|---|
Monoamine metabolites in lumbar CSF: the question of their origin in relation to clinical studies.
Topics: Animals; Biological Transport, Active; Brain; Cats; Cerebral Ventricles; Cerebrospinal Fluid; Choroi | 1974 |
1 trial available for probenecid and Spinal Cord Injuries
| Article | Year |
|---|---|
Oral probenecid improves sperm motility in men with spinal cord injury.
Topics: Administration, Oral; Adult; Humans; Infertility, Male; Male; Middle Aged; Probenecid; Sperm Motilit | 2018 |
Oral probenecid improves sperm motility in men with spinal cord injury.
Topics: Administration, Oral; Adult; Humans; Infertility, Male; Male; Middle Aged; Probenecid; Sperm Motilit | 2018 |
Oral probenecid improves sperm motility in men with spinal cord injury.
Topics: Administration, Oral; Adult; Humans; Infertility, Male; Male; Middle Aged; Probenecid; Sperm Motilit | 2018 |
Oral probenecid improves sperm motility in men with spinal cord injury.
Topics: Administration, Oral; Adult; Humans; Infertility, Male; Male; Middle Aged; Probenecid; Sperm Motilit | 2018 |
1 other study available for probenecid and Spinal Cord Injuries
| Article | Year |
|---|---|
Proteomic insight of seminal plasma in spinal cord injured men submitted to oral probenecid treatment for improved motility.
Topics: Chromatography, Liquid; Humans; Male; Probenecid; Prospective Studies; Proteomics; Semen; Sperm Moti | 2021 |