probenecid has been researched along with Retinal Perforations in 2 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Retinal Perforations: Perforations through the whole thickness of the retina including the macula as the result of inflammation, trauma, degeneration, etc. The concept includes retinal breaks, tears, dialyses, and holes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Outward and inward permeability of carboxyfluorescein across the blood-retinal barrier were measured fluorophotometrically in seven cynomolgus monkey eyes with experimental rhegmatogenous retinal detachment." | 7.67 | Permeability of the blood-retinal barrier to carboxyfluorescein in eyes with rhegmatogenous retinal detachment. ( Pederson, JE; Tsuboi, S, 1987) |
| "Outward and inward permeability of carboxyfluorescein across the blood-retinal barrier were measured fluorophotometrically in seven cynomolgus monkey eyes with experimental rhegmatogenous retinal detachment." | 3.67 | Permeability of the blood-retinal barrier to carboxyfluorescein in eyes with rhegmatogenous retinal detachment. ( Pederson, JE; Tsuboi, S, 1987) |
| "Fluorescein transport was inhibited by probenecid." | 1.27 | Experimental retinal detachment. VI. The permeability of the blood-retinal barrier. ( Cantrill, HL; Pederson, JE, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cantrill, HL | 1 |
| Pederson, JE | 2 |
| Tsuboi, S | 1 |
2 other studies available for probenecid and Retinal Perforations
| Article | Year |
|---|---|
Experimental retinal detachment. VI. The permeability of the blood-retinal barrier.
Topics: Animals; Anterior Chamber; Capillary Permeability; Female; Fluorescein; Fluoresceins; Kinetics; Maca | 1984 |
Permeability of the blood-retinal barrier to carboxyfluorescein in eyes with rhegmatogenous retinal detachment.
Topics: Animals; Biological Transport; Blood-Retinal Barrier; Capillary Permeability; Eye; Fluoresceins; Inj | 1987 |