probenecid has been researched along with Retinal Detachment in 2 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Retinal Detachment: Separation of the inner layers of the retina (neural retina) from the pigment epithelium. Retinal detachment occurs more commonly in men than in women, in eyes with degenerative myopia, in aging and in aphakia. It may occur after an uncomplicated cataract extraction, but it is seen more often if vitreous humor has been lost during surgery. (Dorland, 27th ed; Newell, Ophthalmology: Principles and Concepts, 7th ed, p310-12).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Outward and inward permeability of carboxyfluorescein across the blood-retinal barrier were measured fluorophotometrically in seven cynomolgus monkey eyes with experimental rhegmatogenous retinal detachment." | 7.67 | Permeability of the blood-retinal barrier to carboxyfluorescein in eyes with rhegmatogenous retinal detachment. ( Pederson, JE; Tsuboi, S, 1987) |
| "Outward and inward permeability of carboxyfluorescein across the blood-retinal barrier were measured fluorophotometrically in seven cynomolgus monkey eyes with experimental rhegmatogenous retinal detachment." | 3.67 | Permeability of the blood-retinal barrier to carboxyfluorescein in eyes with rhegmatogenous retinal detachment. ( Pederson, JE; Tsuboi, S, 1987) |
| "Fluorescein transport was inhibited by probenecid." | 1.27 | Experimental retinal detachment. VI. The permeability of the blood-retinal barrier. ( Cantrill, HL; Pederson, JE, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cantrill, HL | 1 |
| Pederson, JE | 2 |
| Tsuboi, S | 1 |
2 other studies available for probenecid and Retinal Detachment
| Article | Year |
|---|---|
Experimental retinal detachment. VI. The permeability of the blood-retinal barrier.
Topics: Animals; Anterior Chamber; Capillary Permeability; Female; Fluorescein; Fluoresceins; Kinetics; Maca | 1984 |
Permeability of the blood-retinal barrier to carboxyfluorescein in eyes with rhegmatogenous retinal detachment.
Topics: Animals; Biological Transport; Blood-Retinal Barrier; Capillary Permeability; Eye; Fluoresceins; Inj | 1987 |