probenecid has been researched along with Rectal Diseases in 9 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Rectal Diseases: Pathological developments in the RECTUM region of the large intestine (INTESTINE, LARGE).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Eighty-six men with uncomplicated gonorrhoea were entered into a study comparing the efficacy of a single oral dose of 250 mg of ciprofloxacin with a single oral dose of ampicillin 2 g and probenecid 1 g for urethral gonorrhoea and a course of ampicillin, 500 mg four times per day for five days in rectal and pharyngeal infection." | 5.06 | Ciprofloxacin versus ampicillin and probenecid in the treatment of uncomplicated gonorrhoea in men. ( McMillan, A; Scott, GR; Young, H, 1987) |
| "5 g orally) in combination with 1 g of probenecid (instant therapy)." | 2.64 | Treatment of urogenital/rectal gonorrhoea in males and females with epicillin in combination with probenecid. ( de Koning, GA; Michel, MF; Schuller, JL; Stolz, E, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (88.89) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Edwards, LD | 1 |
| Gartner, T | 1 |
| Sands, M | 2 |
| Sellers, T | 1 |
| Sherrard, J | 1 |
| Barlow, D | 1 |
| Stolz, E | 1 |
| Schuller, JL | 1 |
| de Koning, GA | 1 |
| Michel, MF | 1 |
| Jefferiss, FJ | 1 |
| Scott, GR | 1 |
| McMillan, A | 1 |
| Young, H | 1 |
| Gottlieb, A | 1 |
| Mills, J | 1 |
| Altaf, SW | 1 |
| Dicaprio, JM | 1 |
5 trials available for probenecid and Rectal Diseases
| Article | Year |
|---|---|
Comparison between bacampicillin and amoxycillin in treating genital and extragenital infection with Neisseria gonorrhoeae and pharyngeal infection with Neisseria meningitidis.
Topics: Amoxicillin; Ampicillin; Anus Diseases; Bacterial Infections; Drug Therapy, Combination; Female; Gen | 1984 |
Treatment of urogenital/rectal gonorrhoea in males and females with epicillin in combination with probenecid.
Topics: Administration, Oral; Ampicillin; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, Combinati | 1978 |
Ciprofloxacin versus ampicillin and probenecid in the treatment of uncomplicated gonorrhoea in men.
Topics: Ampicillin; Ciprofloxacin; Gonorrhea; Humans; Infections; Male; Microbial Sensitivity Tests; Pharyng | 1987 |
Cefuroxime axetil for treatment of uncomplicated gonorrhea.
Topics: Adolescent; Adult; Aged; Amoxicillin; Cefuroxime; Cephalosporins; Drug Therapy, Combination; Gonorrh | 1986 |
Treatment of anorectal gonorrhoea infection in males and females with oral ampicillin.
Topics: Administration, Oral; Adolescent; Adult; Ampicillin; Anus Diseases; Drug Therapy, Combination; Femal | 1986 |
4 other studies available for probenecid and Rectal Diseases
| Article | Year |
|---|---|
Treatment of anorectal gonorrhea infections in men.
Topics: Administration, Oral; Anus Diseases; Gonorrhea; Humans; Injections, Intramuscular; Male; Penicillin | 1980 |
Therapy of anorectal gonorrhea in men. Efficacy of oral antibiotic regimens.
Topics: Administration, Oral; Ampicillin; Drug Combinations; Gonorrhea; Humans; Male; Probenecid; Rectal Dis | 1980 |
Gonorrhoea in men: clinical and diagnostic aspects.
Topics: Adolescent; Adult; Aged; Ampicillin; Anti-Bacterial Agents; Chlamydia Infections; Chlamydia trachoma | 1996 |
Venereal disease and the homosexual.
Topics: Ampicillin; Anus Diseases; Gonorrhea; Homosexuality; Humans; Male; Penicillin G Procaine; Probenecid | 1976 |