Page last updated: 2024-11-03

probenecid and Recrudescence

probenecid has been researched along with Recrudescence in 23 studies

Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.

Research Excerpts

ExcerptRelevanceReference
"The therapeutic efficacy of decloxacillin or flucloxacillin, 1--2 g orally with probenecid twice daily was evaluated in staphylococcal infections."7.66Dicloxacillin and flucloxacillin twice daily with probenecid in staphylococcal infections. A clinical and pharmakokinetic evaluation. ( Hedström, SA; Kahlmeter, G, 1980)
"The therapeutic efficacy of decloxacillin or flucloxacillin, 1--2 g orally with probenecid twice daily was evaluated in staphylococcal infections."3.66Dicloxacillin and flucloxacillin twice daily with probenecid in staphylococcal infections. A clinical and pharmakokinetic evaluation. ( Hedström, SA; Kahlmeter, G, 1980)
"Recurrent pelvic inflammatory disease was associated with an almost 2-fold increase in infertility and more than 4-fold increase in CPP."2.76Recurrent PID, subsequent STI, and reproductive health outcomes: findings from the PID evaluation and clinical health (PEACH) study. ( Bass, D; Haggerty, C; Ness, RB; Trent, M, 2011)
"Women with mild-to-moderate pelvic inflammatory disease were assessed after treatment initiation at 5 days for tenderness (n = 713) and at 30 days for tenderness, cervical infections and endometritis (n = 298)."2.73Do short-term markers of treatment efficacy predict long-term sequelae of pelvic inflammatory disease? ( Bass, DC; Kip, KE; Nelson, DB; Ness, RB; Peipert, JF; Richter, HE; Schubeck, D; Soper, DE; Trautmann, GM; Trout, W, 2008)
" Dose-dependent asymptomatic proteinuria (39%) and serum creatinine elevation (24%) were the most common adverse events thought to be related to cidofovir."2.69Randomized, controlled study of the safety and efficacy of intravenous cidofovir for the treatment of relapsing cytomegalovirus retinitis in patients with AIDS. ( Hardy, WD; Holland, GN; Ives, DV; Jaffe, HS; Johnson, M; Kemper, CA; Kramer, F; Kuppermann, BD; Lalezari, JP; Lewis, RA; McKinley, GF; Nelson, R; Northfelt, DW; Ruby, AE; Simon, GL; Stagg, RJ; Weinberg, DV; Wolitz, RA; Youle, M, 1998)
"probenecid, 109 were followed."1.25Ampicillin plus probenecid compared with procaine penicillin plus probenecid in the treatment of gonorrhoea. ( Seth, AD; Taylor, PK, 1975)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199018 (78.26)18.7374
1990's1 (4.35)18.2507
2000's3 (13.04)29.6817
2010's1 (4.35)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Trent, M1
Bass, D1
Ness, RB2
Haggerty, C1
van Vliet, EA1
Redeker, S1
Aronica, E1
Edelbroek, PM1
Gorter, JA1
Trautmann, GM1
Kip, KE1
Richter, HE1
Soper, DE1
Peipert, JF1
Nelson, DB1
Trout, W1
Schubeck, D1
Bass, DC1
van Praag, HM1
de Haan, S1
Sandström, E1
Jonsson, A1
Holterman, M1
Wallmark, G1
Hedström, SA2
Kahlmeter, G1
Lalezari, JP1
Holland, GN1
Kramer, F1
McKinley, GF1
Kemper, CA1
Ives, DV1
Nelson, R1
Hardy, WD1
Kuppermann, BD1
Northfelt, DW1
Youle, M1
Johnson, M1
Lewis, RA1
Weinberg, DV1
Simon, GL1
Wolitz, RA1
Ruby, AE1
Stagg, RJ1
Jaffe, HS1
Chakrabarti, S1
Collingham, KE1
Osman, H1
Fegan, CD1
Milligan, DW1
Frank, M1
Many, M1
Sperling, O1
de Koning, GA1
Stolz, E1
Michel, MF1
Taylor, PK1
Seth, AD2
Malmborg, AS1
Molin, L1
Nyström, B1
Karney, WW1
Turck, M1
Holmes, KK1
Brown, ST1
McMinn, T1
Savage, GM1
Judson, FN1
Allaman, J1
Dans, PE1
Ball, GV1
Freeman, D1
Rodin, P1
Willcox, RR1
Lopez, WA1
Münnich, D1
Békési, S1
Lakatos, M1
Bardovics, E1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparative Effectiveness Clinical Early of Transvaginal and Laparoscopic Approaches for Drainage of Tubo -Ovarian Abscess. Randomized Noninferiority[NCT03166982]80 participants (Anticipated)Interventional2016-10-26Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

5 trials available for probenecid and Recrudescence

ArticleYear
Recurrent PID, subsequent STI, and reproductive health outcomes: findings from the PID evaluation and clinical health (PEACH) study.
    Sexually transmitted diseases, 2011, Volume: 38, Issue:9

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Cefoxitin; Chronic Pain; Doxycycline; Female; Follow-Up St

2011
Do short-term markers of treatment efficacy predict long-term sequelae of pelvic inflammatory disease?
    American journal of obstetrics and gynecology, 2008, Volume: 198, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; Cefoxitin; Dose-Response Relationship, Drug; Doxycycline; D

2008
Randomized, controlled study of the safety and efficacy of intravenous cidofovir for the treatment of relapsing cytomegalovirus retinitis in patients with AIDS.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1998, Apr-01, Volume: 17, Issue:4

    Topics: Adolescent; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Creatinine; C

1998
Single-dose oral therapy for uncomplicated gonorrhea: comparison of amoxicillin and ampicillin given with and without probenecid.
    The Journal of infectious diseases, 1974, Volume: 129, Issue:0

    Topics: Administration, Oral; Amines; Ampicillin; Anal Canal; Cervix Uteri; Clinical Trials as Topic; Drug T

1974
Treatment of gonorrhea. Comparison of penicillin G procaine, doxycycline, spectinomycin, and ampicillin.
    JAMA, 1974, Nov-04, Volume: 230, Issue:5

    Topics: Adolescent; Adult; Ampicillin; Anti-Bacterial Agents; Doxycycline; Drug Therapy, Combination; Female

1974

Other Studies

18 other studies available for probenecid and Recrudescence

ArticleYear
Expression of multidrug transporters MRP1, MRP2, and BCRP shortly after status epilepticus, during the latent period, and in chronic epileptic rats.
    Epilepsia, 2005, Volume: 46, Issue:10

    Topics: Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Casse

2005
Chemoprophylaxis of depressions. An attempt to compare lithium with 5-hydroxytryptophan.
    Acta psychiatrica Scandinavica. Supplementum, 1981, Volume: 290

    Topics: 5-Hydroxytryptophan; Adult; Depressive Disorder; Female; Humans; Hydroxyindoleacetic Acid; Lithium;

1981
Detection of repeated gonorrhea by a modified follow-up method.
    Acta dermato-venereologica, 1982, Volume: 62, Issue:5

    Topics: Ampicillin; Coitus; Drug Therapy, Combination; Female; Follow-Up Studies; Gonorrhea; Humans; Intervi

1982
Dicloxacillin and flucloxacillin twice daily with probenecid in staphylococcal infections. A clinical and pharmakokinetic evaluation.
    Scandinavian journal of infectious diseases, 1980, Volume: 12, Issue:3

    Topics: Cloxacillin; Dicloxacillin; Drug Combinations; Drug Evaluation; Drug Therapy, Combination; Floxacill

1980
Cidofovir as primary pre-emptive therapy for post-transplant cytomegalovirus infections.
    Bone marrow transplantation, 2001, Volume: 28, Issue:9

    Topics: Adult; Antiviral Agents; Cidofovir; Cyclosporine; Cytomegalovirus; Cytomegalovirus Infections; Cytos

2001
Familial renal hypouricaemia: two additional cases with uric acid lithiasis.
    British journal of urology, 1979, Volume: 51, Issue:2

    Topics: Adult; Calcium; Humans; Jews; Kidney Calculi; Kidney Diseases; Male; Pedigree; Probenecid; Pyrazinam

1979
[Oral treatment of uncomplicated, urogenital and/or rectal gonorrhea with amoxicillin and probenecid].
    Nederlands tijdschrift voor geneeskunde, 1978, Mar-25, Volume: 122, Issue:12

    Topics: Administration, Oral; Amoxicillin; Ampicillin; Drug Therapy, Combination; Female; Gonorrhea; Humans;

1978
Ampicillin plus probenecid compared with procaine penicillin plus probenecid in the treatment of gonorrhoea.
    The British journal of venereal diseases, 1975, Volume: 51, Issue:3

    Topics: Adolescent; Adult; Ampicillin; Drug Therapy, Combination; Gonorrhea; Humans; Microbial Sensitivity T

1975
Pivampicillin combined with probenecid in the treatment of acute uncomplicated gonorrhoea.
    Acta dermato-venereologica, 1973, Volume: 53, Issue:6

    Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Ampicillin; Drug Therapy, Combination; Femal

1973
Treatment of acute gonococcal urethritis in Bangkok, Thailand.
    The British journal of venereal diseases, 1974, Volume: 50, Issue:4

    Topics: Acute Disease; Ampicillin; Drug Therapy, Combination; Gonorrhea; Humans; Injections, Intramuscular;

1974
Spectinomycin related to the chemotherapy of gonorrhea.
    Infection, 1973, Volume: 1, Issue:4

    Topics: Administration, Oral; Ampicillin; Doxycycline; Female; Gonorrhea; Humans; Injections; Kanamycin; Mal

1973
Management of chronic and recurrent gout.
    Modern treatment, 1971, Volume: 8, Issue:4

    Topics: Adrenocorticotropic Hormone; Allopurinol; Chronic Disease; Colchicine; Dexamethasone; Diet Therapy;

1971
Treatment of gonorrhoea with cotrimoxazole, procaine penicillin alone, and procaine penicillin plus probenecid.
    The British journal of venereal diseases, 1972, Volume: 48, Issue:6

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Drug Combinations; Folic Acid Antagonists; Follow-Up Studi

1972
Amoxycillin in the treatment of gonorrhoea.
    The British journal of venereal diseases, 1972, Volume: 48, Issue:6

    Topics: Acute Disease; Amines; Ampicillin; Benzyl Compounds; Cephalosporins; Gonorrhea; Humans; Male; Penici

1972
The management of gonorrhoea and syphilis.
    The Medical journal of Australia, 1973, Feb-10, Volume: 1, Issue:6

    Topics: Female; Gonorrhea; Humans; Male; Penicillin G Benzathine; Penicillin G Procaine; Probenecid; Recurre

1973
Treatment of typhoid carriers with amoxycillin and in combination with probenecid.
    Chemotherapy, 1974, Volume: 20, Issue:1

    Topics: Adult; Aged; Bile; Carrier State; Drug Combinations; Feces; Female; Humans; Male; Microbial Sensitiv

1974
Current therapy of gonorrhea.
    JAMA, 1971, Nov-01, Volume: 218, Issue:5

    Topics: Administration, Oral; Adult; Anti-Bacterial Agents; Arthritis; Cervix Mucus; Female; Gonorrhea; Huma

1971
General and local antibiotic treatment of chronic osteomyelitis.
    Scandinavian journal of infectious diseases, 1969, Volume: 1, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Aged; Blood Sedimentation; C-Reactive Protein; Child; Chlor

1969