probenecid has been researched along with Recrudescence in 23 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The therapeutic efficacy of decloxacillin or flucloxacillin, 1--2 g orally with probenecid twice daily was evaluated in staphylococcal infections." | 7.66 | Dicloxacillin and flucloxacillin twice daily with probenecid in staphylococcal infections. A clinical and pharmakokinetic evaluation. ( Hedström, SA; Kahlmeter, G, 1980) |
| "The therapeutic efficacy of decloxacillin or flucloxacillin, 1--2 g orally with probenecid twice daily was evaluated in staphylococcal infections." | 3.66 | Dicloxacillin and flucloxacillin twice daily with probenecid in staphylococcal infections. A clinical and pharmakokinetic evaluation. ( Hedström, SA; Kahlmeter, G, 1980) |
| "Recurrent pelvic inflammatory disease was associated with an almost 2-fold increase in infertility and more than 4-fold increase in CPP." | 2.76 | Recurrent PID, subsequent STI, and reproductive health outcomes: findings from the PID evaluation and clinical health (PEACH) study. ( Bass, D; Haggerty, C; Ness, RB; Trent, M, 2011) |
| "Women with mild-to-moderate pelvic inflammatory disease were assessed after treatment initiation at 5 days for tenderness (n = 713) and at 30 days for tenderness, cervical infections and endometritis (n = 298)." | 2.73 | Do short-term markers of treatment efficacy predict long-term sequelae of pelvic inflammatory disease? ( Bass, DC; Kip, KE; Nelson, DB; Ness, RB; Peipert, JF; Richter, HE; Schubeck, D; Soper, DE; Trautmann, GM; Trout, W, 2008) |
| " Dose-dependent asymptomatic proteinuria (39%) and serum creatinine elevation (24%) were the most common adverse events thought to be related to cidofovir." | 2.69 | Randomized, controlled study of the safety and efficacy of intravenous cidofovir for the treatment of relapsing cytomegalovirus retinitis in patients with AIDS. ( Hardy, WD; Holland, GN; Ives, DV; Jaffe, HS; Johnson, M; Kemper, CA; Kramer, F; Kuppermann, BD; Lalezari, JP; Lewis, RA; McKinley, GF; Nelson, R; Northfelt, DW; Ruby, AE; Simon, GL; Stagg, RJ; Weinberg, DV; Wolitz, RA; Youle, M, 1998) |
| "probenecid, 109 were followed." | 1.25 | Ampicillin plus probenecid compared with procaine penicillin plus probenecid in the treatment of gonorrhoea. ( Seth, AD; Taylor, PK, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (78.26) | 18.7374 |
| 1990's | 1 (4.35) | 18.2507 |
| 2000's | 3 (13.04) | 29.6817 |
| 2010's | 1 (4.35) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Trent, M | 1 |
| Bass, D | 1 |
| Ness, RB | 2 |
| Haggerty, C | 1 |
| van Vliet, EA | 1 |
| Redeker, S | 1 |
| Aronica, E | 1 |
| Edelbroek, PM | 1 |
| Gorter, JA | 1 |
| Trautmann, GM | 1 |
| Kip, KE | 1 |
| Richter, HE | 1 |
| Soper, DE | 1 |
| Peipert, JF | 1 |
| Nelson, DB | 1 |
| Trout, W | 1 |
| Schubeck, D | 1 |
| Bass, DC | 1 |
| van Praag, HM | 1 |
| de Haan, S | 1 |
| Sandström, E | 1 |
| Jonsson, A | 1 |
| Holterman, M | 1 |
| Wallmark, G | 1 |
| Hedström, SA | 2 |
| Kahlmeter, G | 1 |
| Lalezari, JP | 1 |
| Holland, GN | 1 |
| Kramer, F | 1 |
| McKinley, GF | 1 |
| Kemper, CA | 1 |
| Ives, DV | 1 |
| Nelson, R | 1 |
| Hardy, WD | 1 |
| Kuppermann, BD | 1 |
| Northfelt, DW | 1 |
| Youle, M | 1 |
| Johnson, M | 1 |
| Lewis, RA | 1 |
| Weinberg, DV | 1 |
| Simon, GL | 1 |
| Wolitz, RA | 1 |
| Ruby, AE | 1 |
| Stagg, RJ | 1 |
| Jaffe, HS | 1 |
| Chakrabarti, S | 1 |
| Collingham, KE | 1 |
| Osman, H | 1 |
| Fegan, CD | 1 |
| Milligan, DW | 1 |
| Frank, M | 1 |
| Many, M | 1 |
| Sperling, O | 1 |
| de Koning, GA | 1 |
| Stolz, E | 1 |
| Michel, MF | 1 |
| Taylor, PK | 1 |
| Seth, AD | 2 |
| Malmborg, AS | 1 |
| Molin, L | 1 |
| Nyström, B | 1 |
| Karney, WW | 1 |
| Turck, M | 1 |
| Holmes, KK | 1 |
| Brown, ST | 1 |
| McMinn, T | 1 |
| Savage, GM | 1 |
| Judson, FN | 1 |
| Allaman, J | 1 |
| Dans, PE | 1 |
| Ball, GV | 1 |
| Freeman, D | 1 |
| Rodin, P | 1 |
| Willcox, RR | 1 |
| Lopez, WA | 1 |
| Münnich, D | 1 |
| Békési, S | 1 |
| Lakatos, M | 1 |
| Bardovics, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparative Effectiveness Clinical Early of Transvaginal and Laparoscopic Approaches for Drainage of Tubo -Ovarian Abscess. Randomized Noninferiority[NCT03166982] | 80 participants (Anticipated) | Interventional | 2016-10-26 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 trials available for probenecid and Recrudescence
| Article | Year |
|---|---|
Recurrent PID, subsequent STI, and reproductive health outcomes: findings from the PID evaluation and clinical health (PEACH) study.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Cefoxitin; Chronic Pain; Doxycycline; Female; Follow-Up St | 2011 |
Do short-term markers of treatment efficacy predict long-term sequelae of pelvic inflammatory disease?
Topics: Administration, Oral; Adolescent; Adult; Cefoxitin; Dose-Response Relationship, Drug; Doxycycline; D | 2008 |
Randomized, controlled study of the safety and efficacy of intravenous cidofovir for the treatment of relapsing cytomegalovirus retinitis in patients with AIDS.
Topics: Adolescent; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Creatinine; C | 1998 |
Single-dose oral therapy for uncomplicated gonorrhea: comparison of amoxicillin and ampicillin given with and without probenecid.
Topics: Administration, Oral; Amines; Ampicillin; Anal Canal; Cervix Uteri; Clinical Trials as Topic; Drug T | 1974 |
Treatment of gonorrhea. Comparison of penicillin G procaine, doxycycline, spectinomycin, and ampicillin.
Topics: Adolescent; Adult; Ampicillin; Anti-Bacterial Agents; Doxycycline; Drug Therapy, Combination; Female | 1974 |
18 other studies available for probenecid and Recrudescence
| Article | Year |
|---|---|
Expression of multidrug transporters MRP1, MRP2, and BCRP shortly after status epilepticus, during the latent period, and in chronic epileptic rats.
Topics: Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Casse | 2005 |
Chemoprophylaxis of depressions. An attempt to compare lithium with 5-hydroxytryptophan.
Topics: 5-Hydroxytryptophan; Adult; Depressive Disorder; Female; Humans; Hydroxyindoleacetic Acid; Lithium; | 1981 |
Detection of repeated gonorrhea by a modified follow-up method.
Topics: Ampicillin; Coitus; Drug Therapy, Combination; Female; Follow-Up Studies; Gonorrhea; Humans; Intervi | 1982 |
Dicloxacillin and flucloxacillin twice daily with probenecid in staphylococcal infections. A clinical and pharmakokinetic evaluation.
Topics: Cloxacillin; Dicloxacillin; Drug Combinations; Drug Evaluation; Drug Therapy, Combination; Floxacill | 1980 |
Cidofovir as primary pre-emptive therapy for post-transplant cytomegalovirus infections.
Topics: Adult; Antiviral Agents; Cidofovir; Cyclosporine; Cytomegalovirus; Cytomegalovirus Infections; Cytos | 2001 |
Familial renal hypouricaemia: two additional cases with uric acid lithiasis.
Topics: Adult; Calcium; Humans; Jews; Kidney Calculi; Kidney Diseases; Male; Pedigree; Probenecid; Pyrazinam | 1979 |
[Oral treatment of uncomplicated, urogenital and/or rectal gonorrhea with amoxicillin and probenecid].
Topics: Administration, Oral; Amoxicillin; Ampicillin; Drug Therapy, Combination; Female; Gonorrhea; Humans; | 1978 |
Ampicillin plus probenecid compared with procaine penicillin plus probenecid in the treatment of gonorrhoea.
Topics: Adolescent; Adult; Ampicillin; Drug Therapy, Combination; Gonorrhea; Humans; Microbial Sensitivity T | 1975 |
Pivampicillin combined with probenecid in the treatment of acute uncomplicated gonorrhoea.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Ampicillin; Drug Therapy, Combination; Femal | 1973 |
Treatment of acute gonococcal urethritis in Bangkok, Thailand.
Topics: Acute Disease; Ampicillin; Drug Therapy, Combination; Gonorrhea; Humans; Injections, Intramuscular; | 1974 |
Spectinomycin related to the chemotherapy of gonorrhea.
Topics: Administration, Oral; Ampicillin; Doxycycline; Female; Gonorrhea; Humans; Injections; Kanamycin; Mal | 1973 |
Management of chronic and recurrent gout.
Topics: Adrenocorticotropic Hormone; Allopurinol; Chronic Disease; Colchicine; Dexamethasone; Diet Therapy; | 1971 |
Treatment of gonorrhoea with cotrimoxazole, procaine penicillin alone, and procaine penicillin plus probenecid.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Drug Combinations; Folic Acid Antagonists; Follow-Up Studi | 1972 |
Amoxycillin in the treatment of gonorrhoea.
Topics: Acute Disease; Amines; Ampicillin; Benzyl Compounds; Cephalosporins; Gonorrhea; Humans; Male; Penici | 1972 |
The management of gonorrhoea and syphilis.
Topics: Female; Gonorrhea; Humans; Male; Penicillin G Benzathine; Penicillin G Procaine; Probenecid; Recurre | 1973 |
Treatment of typhoid carriers with amoxycillin and in combination with probenecid.
Topics: Adult; Aged; Bile; Carrier State; Drug Combinations; Feces; Female; Humans; Male; Microbial Sensitiv | 1974 |
Current therapy of gonorrhea.
Topics: Administration, Oral; Adult; Anti-Bacterial Agents; Arthritis; Cervix Mucus; Female; Gonorrhea; Huma | 1971 |
General and local antibiotic treatment of chronic osteomyelitis.
Topics: Administration, Oral; Adolescent; Adult; Aged; Blood Sedimentation; C-Reactive Protein; Child; Chlor | 1969 |