probenecid has been researched along with Pyrexia in 7 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fever was induced and maintained for 12 h by injecting Escherichia coli endotoxin (0." | 5.29 | The effect of induced fever on the biokinetics of norfloxacin and its interaction with probenecid in goats. ( Jha, K; Roy, BK; Singh, RC, 1996) |
| "Fever was induced and maintained for 12 h by injecting Escherichia coli endotoxin (0." | 1.29 | The effect of induced fever on the biokinetics of norfloxacin and its interaction with probenecid in goats. ( Jha, K; Roy, BK; Singh, RC, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (71.43) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| van Gelderen, CJ | 1 |
| Jha, K | 1 |
| Roy, BK | 1 |
| Singh, RC | 1 |
| Rao, GS | 1 |
| Ramesh, S | 1 |
| Ahmad, AH | 1 |
| Tripathi, HC | 1 |
| Sharma, LD | 1 |
| Malik, JK | 1 |
| Crawford, IL | 1 |
| Kennedy, JI | 1 |
| Lipton, JM | 1 |
| Ojeda, SR | 1 |
| Sirko, S | 1 |
| Bishai, I | 1 |
| Coceani, F | 1 |
| Tattersall, MH | 2 |
| Spiers, AS | 2 |
| Darrell, JH | 1 |
| Hutchinson, RM | 1 |
| Gaya, H | 1 |
1 trial available for probenecid and Pyrexia
| Article | Year |
|---|---|
'One-visit' therapy for pelvic inflammatory disease.
Topics: Acute Disease; Blood Sedimentation; Drug Therapy, Combination; Escherichia coli; Female; Fever; Huma | 1980 |
6 other studies available for probenecid and Pyrexia
| Article | Year |
|---|---|
The effect of induced fever on the biokinetics of norfloxacin and its interaction with probenecid in goats.
Topics: Analysis of Variance; Animals; Drug Interactions; Endotoxins; Escherichia coli; Female; Fever; Goats | 1996 |
Effects of endotoxin-induced fever and probenecid on disposition of enrofloxacin and its metabolite ciprofloxacin after intravascular administration of enrofloxacin in goats.
Topics: Animals; Anti-Infective Agents; Area Under Curve; Ciprofloxacin; Drug Interactions; Endotoxins; Enro | 2000 |
Effects of central administation of probenecid on fevers produced by leukocytic pyrogen and PGE2 in the rabbit.
Topics: Animals; Body Temperature; Endotoxins; Fever; Injections, Intraventricular; Male; Probenecid; Prosta | 1979 |
Prostaglandin formation in the hypothalamus in vivo: effect of pyrogens.
Topics: Animals; Body Temperature; Cats; Dinoprostone; Endotoxins; Female; Fever; Hypothalamus; Indomethacin | 1989 |
Initial therapy with combination of five antibiotics in febrile patients with leukaemia and neutropenia.
Topics: Administration, Oral; Agranulocytosis; Anemia, Aplastic; Anti-Bacterial Agents; Bacterial Infections | 1972 |
Empirical antibiotic therapy in febrile patients with neutropenia and malignant disease.
Topics: Agranulocytosis; Anti-Bacterial Agents; Bacterial Infections; Carbenicillin; Cephalothin; Clindamyci | 1973 |