probenecid has been researched along with Purine Pyrimidine Metabolism, Inborn Errors in 8 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "An existing generalized mass action system model of human uric acid (UA) metabolism was used to formulate the fuzzy optimization method for detecting two types of enzymopathies: hyperuricemia caused by phosphoribosylpyrophosphate synthetase (PRPPS) overactivity and Lesch-Nyhan syndrome." | 3.79 | Fuzzy optimization for detecting enzyme targets of human uric acid metabolism. ( Hsu, KC; Wang, FS, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (87.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hsu, KC | 1 |
| Wang, FS | 1 |
| Stapleton, FB | 1 |
| Nyhan, WL | 1 |
| Borden, M | 1 |
| Kaufman, IA | 1 |
| Boss, GR | 1 |
| Seegmiller, JE | 1 |
| Sperling, O | 1 |
| Weinberger, A | 1 |
| Benjamin, D | 1 |
| Pinkhas, J | 1 |
| de Vries, A | 1 |
| de Gery, A | 1 |
| Auscher, C | 1 |
| Saporta, L | 1 |
| Delbarre, F | 1 |
| Simkin, PA | 1 |
| Skeith, MD | 1 |
| Healey, LA | 1 |
| Holmes, EW | 1 |
| Kelley, WN | 1 |
| Manzke, H | 1 |
| Harms, D | 1 |
| Dörner, K | 1 |
1 review available for probenecid and Purine Pyrimidine Metabolism, Inborn Errors
| Article | Year |
|---|---|
Hyperuricemia and gout. Classification, complications and management.
Topics: Acute Disease; Allopurinol; Arthritis; Aspirin; Colchicine; Coronary Disease; Diuretics; Gout; Human | 1979 |
1 trial available for probenecid and Purine Pyrimidine Metabolism, Inborn Errors
| Article | Year |
|---|---|
Treatment of gout and hyperuricaemia by benzbromarone, ethyl 2 (dibromo-3,5 hydroxy-4 benzoyl)-3 benzofuran.
Topics: Benzoates; Bromine; Clinical Trials as Topic; Creatinine; Gout; Humans; Hypoxanthines; Probenecid; P | 1974 |
6 other studies available for probenecid and Purine Pyrimidine Metabolism, Inborn Errors
| Article | Year |
|---|---|
Fuzzy optimization for detecting enzyme targets of human uric acid metabolism.
Topics: Algorithms; Diet; Drug Design; Drug Discovery; Fuzzy Logic; Humans; Hyperuricemia; Kinetics; Lesch-N | 2013 |
Renal pathogenesis of familial hyperuricemia: studies in two kindreds.
Topics: Adolescent; Ascorbic Acid; Humans; Kidney; Kidney Tubules; Male; Probenecid; Protein Binding; Purine | 1981 |
Hereditary renal hypouricemia: heterogeneity of tubular abnormality.
Topics: Adult; Calcium; Female; Humans; Male; Middle Aged; Probenecid; Purine-Pyrimidine Metabolism, Inborn | 1978 |
Suppression of uric acid secretion in a patient with renal hypouricemia.
Topics: Circadian Rhythm; Creatinine; Female; Humans; Kidney Diseases; Middle Aged; Probenecid; Purine-Pyrim | 1974 |
Reevaluation of the pyrazinamide suppression test.
Topics: Evaluation Studies as Topic; Glomerular Filtration Rate; Male; Methods; Probenecid; Purine-Pyrimidin | 1974 |
[Treatment of congenital hyperuricemia].
Topics: Adolescent; Allopurinol; Athetosis; Child; Humans; Hypoxanthines; Intellectual Disability; Lesch-Nyh | 1971 |